Dcra003117.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila cracens
Gene Symbol
ftz-f1
Assembly
GCA_035042505.1
Location
JAWNLF010000188.1:4275710-4288416[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 2 1.8e+04 -13.8 29.3 43 160 26 158 4 168 0.44
2 4 0.79 7e+03 -4.0 15.9 44 136 92 170 76 205 0.41
3 4 2.2e-19 2e-15 57.1 0.8 1 78 332 408 332 429 0.73
4 4 3.5e-72 3.1e-68 231.0 1.7 157 408 531 775 497 777 0.91

Sequence Information

Coding Sequence
ATGTTATTAGAAATGGATCAACAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTGTCGCCGTTTAGCATGCAACTCGAACAACAGCAGCCCGCGAGTCCGGCGCACAGCAACACTAACAacgctaacaacaacaacaacagtaccaacagcaacaacaacaacagcagcagtaatagcaacaacaacaacagcaataacaacgatAACGATACAAATGCATTGAGCAATTCCGATAACGATTACAGTGCATACACTCTGCAACTGGGcagtcatcagcagcagcagcagcagcaacactcacATCACCcacatcaccagcagcagcagcagcaacaacaacagcagcattaccaacaacaacaacaacagaatattgccaacaacaatgcgaatgCAGCGGCGAATCAATTCAATGCTTCCTCCTATtcgtatatatacaatttcgATTCACAATACATATTCCCGACAGGCTATCAGGAAACGAACTCATCGCATTCGCAGCAAAGTGCAAATGGAGCCGGCAATgccgcagcagctggcaactcTGGCCAGCTCCTGaacggtggcagcagcagctcgacAGGTAATAGTTACATGCTGTTGCCACCGGGCGCTGGTGGCacctctgctgctgccgctgcccatATGTCCGGCAATGTGGGCGGCAATCCGGCCGCGGGCGTAAGTGGAACCGCTGCCGGCGGTGGTCATCATGGCGGCACCAGCGCCAGTTCTGGCGGCGGCGAAGCCATCGATTTTAAGCATCTGTTCGAGGAGCTGTGCCCCGTCTGCGGAGACAAGGTGAGCGGCTATCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACcgttcaaaacaaaaaggtCTACACTTGCGTGGCGGAGCGCTCCTGCCACATCGACAAGACGCAGCGCAAACGTTGTCCATATTGTCGATTCCAGAAGTGCCTAGAGGTGGGCATGAAACTAGAGGCGGTTCGAGCGGATCGGATGCGTGGCGGTCGCAATAAATTTGGACCCATGTACAAACGGGATCGGGCGCGAAAACTGCAAGTGATGCGTCAGCGGCAACTGGCGCTGCAGGCGTTGCGCAGTTCGATGGGCACGGACATAAAGCCGACGCCTCTCTCGCCGGGCTATCAGCAAGCATAtccaaatatgaatattaagcAAGAAATTCAAATACCTCAGgtATCCTCACTCACACAATCGCCAGACTCATCACCCAGCCCCATTGCTATTGCCTTGGGTCAGGTGAATGCGAGCGGGGGCGGTGTGATAGCCACGCCGATCAATgccggcaatggcaacggtgGCTCCTCACTTGGCAATggcggcaatggcaacaacaacaacaccaacaacaacggcacAGGCAGTGGaagcggaggaggaggaggaggggctGGTGGAGGAGGTAACAATACTGGTGGCAACAACACCGATGGCCTGCAACGCAAtggaaacagcagcaatagcaacagcaacagcagttgccacGAAATCGGCACTGGATCTCTACAGAACTCAGCCGAAGCGAAATTGTGCTTCGATTCTGGCACACATCCATCGAGCACAGCCGACGCGCTTATTGAGCCACTCAGggTCTCACCAATGATACGCGAATTTGTGCAATCGATCGATGATCGGGAATGGCAAACGCAACTTTTTGCGCTACTGCAGAAGCAGACGTACAATCAAGTTGAAGTGGATCTCTTTGAGTTAATGTGTAAAGTGCTTGATCAGAATCTATTCTCACAAGTGGATTGGGCAAGAAACACCGTCTTCTTTAAGGATTTAAAGGTTGACGATCAGATGAAGCTGCTTCAGCATTCTTGGTCCGATATGCTCGTGCTGGATCATTTGCATCATCGCATTCACAACGGTCTGCCCGATGAGACTCAGCTGAATAACGGTCAGGTCTTCAATTTGATGAGTCTTGGTCTGCTGGGTGTGCCACAGCTGGGTGACTATTTCAACGAGCTGCAGAATAAGCTGCAGGAACTGAAGTTCGATATGGGCGACTATGTTTGCATGAAATTCCTAATACTGCTAAATCCAGATGTGCGAGGCATTGTTAACAAGAAGACCGTCTTGGAGGGACATGAGAATGTTCAGGCCGCGCTACTGGATTACACACTGACCTGTTATCCCTCAGTTAATGACAAATTCAGGAGGCTACTTAACATCCTTCCGGAAATACACGCAATGGCCGCACGAGGCGAGGAGCACCTCTACTCAAAGCATTGTGCTGGCAGTGCACCCACACAGACGCTGCTCATGGAGATGCTGCATGCCAAGCGGAAAGTGTAA
Protein Sequence
MLLEMDQQQATVQFISSLNLSPFSMQLEQQQPASPAHSNTNNANNNNNSTNSNNNNSSSNSNNNNSNNNDNDTNALSNSDNDYSAYTLQLGSHQQQQQQQHSHHPHHQQQQQQQQQQHYQQQQQQNIANNNANAAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSANGAGNAAAAGNSGQLLNGGSSSSTGNSYMLLPPGAGGTSAAAAAHMSGNVGGNPAAGVSGTAAGGGHHGGTSASSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSMGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGGGVIATPINAGNGNGGSSLGNGGNGNNNNTNNNGTGSGSGGGGGGAGGGGNNTGGNNTDGLQRNGNSSNSNSNSSCHEIGTGSLQNSAEAKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQELKFDMGDYVCMKFLILLNPDVRGIVNKKTVLEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00485910;
90% Identity
iTF_00508363;
80% Identity
iTF_00497439;