Dcog013011.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila cognata
Gene Symbol
ftz-f1
Assembly
GCA_035041535.1
Location
JAWNLC010000688.1:4640262-4653518[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 2 1.8e+04 -14.4 31.4 42 153 25 157 4 172 0.38
2 4 1.4 1.3e+04 -4.8 18.5 43 125 96 174 76 213 0.42
3 4 1.9e-19 1.7e-15 57.4 0.5 1 78 338 414 338 438 0.74
4 4 2.6e-72 2.3e-68 231.5 1.3 157 408 538 782 502 784 0.91

Sequence Information

Coding Sequence
ATGTTATTAGAAATGGATCAACAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTGTCGCCGTTTAGCATGCAACTCGAACAACAGCAGCCCGCGAGTCCGGCGCACAGCAACACTAACAacgctaacaacaacaacaacaacaacaacagtagcaacagcaacaacaacaataacagcagcagtaatagcaacaacaacaacactaacaatgATAACGATACAAATGCATTGAGCAATTCCGATAACGATTACAGTGCATACACGCTGCAACTGGGGagtcatcagcagcagcagcagcagcaacacccaCATCATAcacatcaccagcagcagcagcaacaacaacagcaacagcagcagcagcattaccaacagcaacaacaacagaatattgccaacaacaatgcgaatgCAGCGGCGAATCAATTCAATGCTTCCTCCTATtcgtatatatacaatttcgATTCACAGTACATATTCCCGACAGGCTATCAGGAAACGAACTCATCGCATTCGCAGCAAAGTGCAAATGGAGCCGGCAATgccgcagcagctggcaactcTGGCCAGCTCCTGaacggtggcagcagcagctcgacaGGTAATAGTTACATGCTGTTGCCACCGGGCGCTGGTGGCacctctgctgctgccgctgcccatATGTCCGGCAATGTGGGCGGCAATCCGGCCGCGGGCGTAAGTGGAACCGCTGCCGGCGGTGGTCATCATGGCGGCACCAGCGCCAGTTCTGGCGGCGGCGAAGCCATCGATTTTAAGCATCTGTTCGAGGAGCTGTGCCCCGTCTGCGGAGACAAGGTGAGCGGCTATCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACcgttcaaaacaaaaaggtCTACACTTGCGTGGCGGAGCGCTCCTGCCACATCGACAAGACGCAGCGCAAACGTTGTCCATATTGTCGATTCCAGAAGTGCCTAGAGGTGGGCATGAAACTAGAGGCGGTTCGAGCGGACCGGATGCGTGGCGGTCGCAATAAATTTGGACCCATGTACAAACGGGATCGGGCGCGAAAACTGCAAGTGATGCGTCAGCGGCAACTGGCGCTGCAGGCGTTGCGCAGTTCGATGGGCACGGACATAAAGCCGACGCCTCTCTCGCCGGGCTATCAGCAAGCATAtccaaatatgaatattaagcAAGAAATTCAAATACCTCAGgtATCCTCACTCACACAATCGCCAGACTCATCGCCCAGCCCCATTGCTATTGCCTTGGGTCAGGTGAATGCGAGCGGGGGCGGTGTGATAGCCACGCCGATCAATgccggcaatggcaatggtgGCTCCTCACTTGGCAAtggcggcaatggcaacaacaacaccaacaacagcggcaCAGGCAGCGGaagcggaggaggaggaggaggggcTGGTGGGGGAGGCAACAATActggtggcaacaacaacatcaccgATGGCCTGCAACGCAAtggaaacagcagcaatagcaacagcaacagcagttgccacGAAATCGGCACTGGATCTCTACAGAACTCAGCCGAAGCGAAATTGTGCTTCGATTCTGGCACACATCCATCGAGCACAGCCGACGCGCTTATTGAGCCACTCAGggTATCACCAATGATACGCGAATTTGTGCAATCGATCGATGATCGGGAATGGCAAACGCAACTTTTTGCGCTACTGCAGAAGCAGACGTACAATCAAGTTGAAGTGGATCTCTTTGAGTTAATGTGTAAAGTGCTTGATCAGAATCTATTCTCACAAGTGGATTGGGCAAGAAACACCGTCTTCTTTAAGGATTTAAAGGTTGACGATCAGATGAAGCTGCTTCAGCATTCTTGGTCCGATATGCTCGTGCTGGATCATTTGCATCATCGCATTCACAACGGTCTGCCCGATGAGACTCAGCTGAATAACGGTCAGGTCTTCAATTTGATGAGTCTTGGTCTGCTGGGTGTGCCACAGCTGGGTGACTATTTCAACGAGCTGCAGAATAAGCTGCAGGAACTGAAGTTCGATATGGGCGACTATGTTTGCATGAAATTCCTAATACTGCTAAATCCAGATGTGCGAGGCATTGTTAACAAGAAGACCGTCTTGGAGGGACATGAGAATGTTCAGGCCGCGCTACTGGATTACACACTGACCTGTTATCCCTCAGTTAATGACAAATTCAGGAGGCTACTTAACATCCTTCCGGAAATACACGCAATGGCCGCACGAGGCGAGGAGCACCTCTACTCAAAGCATTGTGCTGGCAGTGCACCCACACAGACGCTGCTCATGGAGATGCTGCATGCCAAGCGGAAAGTGTAA
Protein Sequence
MLLEMDQQQATVQFISSLNLSPFSMQLEQQQPASPAHSNTNNANNNNNNNNSSNSNNNNNSSSNSNNNNTNNDNDTNALSNSDNDYSAYTLQLGSHQQQQQQQHPHHTHHQQQQQQQQQQQQQHYQQQQQQNIANNNANAAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSANGAGNAAAAGNSGQLLNGGSSSSTGNSYMLLPPGAGGTSAAAAAHMSGNVGGNPAAGVSGTAAGGGHHGGTSASSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSMGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGGGVIATPINAGNGNGGSSLGNGGNGNNNTNNSGTGSGSGGGGGGAGGGGNNTGGNNNITDGLQRNGNSSNSNSNSSCHEIGTGSLQNSAEAKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQELKFDMGDYVCMKFLILLNPDVRGIVNKKTVLEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00485910;
90% Identity
iTF_00508363;
80% Identity
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