Basic Information

Insect: Drosophila carrolli
Gene Symbol: -
Assembly: GCA_018152295.1
Location: JAECXJ010000001.1:10875197-10877581[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.058 4.4 7.9 5.9 3 23 255 275 253 275 0.96

2 12 0.0069 0.52 10.9 0.5 1 23 281 306 281 306 0.93

3 12 0.0023 0.17 12.4 0.7 1 23 313 338 313 338 0.94

4 12 0.00017 0.013 16.0 2.4 1 23 347 369 347 369 0.97

5 12 7.8e-05 0.0059 17.0 0.1 1 23 376 398 376 398 0.97

6 12 0.0063 0.48 11.0 0.5 1 23 404 426 404 426 0.97

7 12 0.024 1.8 9.2 1.3 1 23 432 455 432 455 0.97

8 12 0.01 0.78 10.3 4.5 1 23 461 483 461 483 0.96

9 12 0.00029 0.022 15.2 2.4 2 23 490 511 489 511 0.96

10 12 1.3e-05 0.001 19.4 1.5 1 23 584 607 584 607 0.96

11 12 0.037 2.8 8.6 7.1 1 23 613 635 613 635 0.94

12 12 3e-06 0.00023 21.4 2.3 1 23 641 663 641 663 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.058	4.4	7.9	5.9	3	23	255	275	253	275	0.96
2	12	0.0069	0.52	10.9	0.5	1	23	281	306	281	306	0.93
3	12	0.0023	0.17	12.4	0.7	1	23	313	338	313	338	0.94
4	12	0.00017	0.013	16.0	2.4	1	23	347	369	347	369	0.97
5	12	7.8e-05	0.0059	17.0	0.1	1	23	376	398	376	398	0.97
6	12	0.0063	0.48	11.0	0.5	1	23	404	426	404	426	0.97
7	12	0.024	1.8	9.2	1.3	1	23	432	455	432	455	0.97
8	12	0.01	0.78	10.3	4.5	1	23	461	483	461	483	0.96
9	12	0.00029	0.022	15.2	2.4	2	23	490	511	489	511	0.96
10	12	1.3e-05	0.001	19.4	1.5	1	23	584	607	584	607	0.96
11	12	0.037	2.8	8.6	7.1	1	23	613	635	613	635	0.94
12	12	3e-06	0.00023	21.4	2.3	1	23	641	663	641	663	0.99

Sequence Information

Coding Sequence: ATGAACGAGGGGAGCCAGTACTCCATCCACACGGTGTGCCGCACCTGCCTATCCACACTGGACAATGCGGCGGCCTACGATCTGTTCCGAGTGCCCGGTCTGGCCAAAAAGCTATGCGTGTGCACCTCGTTATCCGTGGAACAGGCGGATGGCTTTCCTAAGAACCTATGCACCGTGTGCTTTTTCAAGCTGAACGACCTGCACGACTTCCAGAAGCAGTGCGTAGACTCAGTGCAGAAGTTCCAGGACATGGTGGCCAGCAACGCCTTCGCCTGCCAAACCAGCTTCGATGTTCTGGATCCAAGTTCTGCCGTCGCGGACCTGCCCGGCGAGGAGGAGGACAACGTCCACTTTGATCCGTTGCTCAACTCCAAGATCGAAATCATCGAGAACGAGGAAGATGTCTTTAAGATGCTGGAATCCGTCGAAAAGGAGGTCGAGGAGGTGGAGATGGAGCTGGAGCAGCCCTTTGGCGACGAATCGCAGGACGACTCCTTTGAGAGCGGCAACGACAACGACCTGGACGCAGACTTTCAGCTCAACAGCAGCGATGATGACGTTCCGTTGGCCCAGCGTAGTCGGCGCGGTTCTGGCCGCGGTTCCAAGGCCAAGGCCAAGCTAAAGGCGGTCGCCAAGCGGCAGGAGGAGGAGGAGGACTCCGAGGATTCTAGCTCTTCGGAGGATTCGGATGGCAATCCCAAAGATAAGCCCAAGCGTAAGAGGATTCCCGCAACGGAGCGGGATCGTCACCGGCTGATCGACTGCCACATCTGCCACCAGAAGTTCAAGAAGGCAATACGCTACGAGGAGCACATGAAGCACCACAACGACCTGCTACCGTTCCAGTGCACCGTCGAGAGTTGCAGGAAAGGCTTCACCACAGCCAACGGGTTGCGCGTCCACGTGGAACACGCCCACACGGAGACGTCGGCCATGCATCCGTGCACATATGAAGGCTGCAACAAGTCCTTTGCCCGACCCGTTCTGCTTAGCTTCCACATGAAACGGGTGCACAAGGTGGACACACCGCAGAGGGACTTCCCCTGCACCGAATGCGAGAAGGTCTTCCGCTGCCCCACCGCCCTCAAGAAGCATATGTACAAGCATACCGGCGAGGAGCTGCCCTTCGCCTGCGAGATCTGCGGCAAGCGCTTCCCGATCAACAGTGTGCTGCGCGATCATCTGCTTCGGCATGCAGGCATCAAGAACCATGTGTGTCCCTACTGCGGAGTGGGCAAGACTACGCGCCAGGAGTGGAACAAGCACATCCTGACCCACACCAAGGAAAAGAAGTACGAGTGCCGGCAGTGCGACCACGCCTCCCACAACAAACAGGCGCTGGCCAACCACGTGAAGGTGGTCCACGAAAAGCGCAAGGACTTCGCCTGCCAGTACTGTGGAAAGACCTTTGGGAAGTCGCACGCCTGCAAGATCCACGAGAGGAGTCACACCGGGGAGAAGTGTTGTGAGTGCAAGATCTGTGGAAAGGTGTTCCTCTTTGAGAAGGGCCTTACCAAGCATTTGAAGACGCACGAGAAGAGGGATCTTCCCAAGACGCAGGGGGCCAATCCCTTGATGGGCGACGGTGCCAGTGGTTCTTCGACAATTGCCAAGCCCAGTCCGCATCTGCGAGGTCGCGTCGAACGGGTGGACATTGCCCAGCTAGCGGGAACGGTGGCCAATCCGATTCCCTCGGTGAACCTGCCCTCGTGGTCGCCGCAGGTGAATTTCACCAAGAAGGAGGGCCAGCACATCTGTCCGGATTGCGGCAAGGGTTTCAACCATGTTAGCAACATGAAACTGCACTATAAGGTGGTTCACCAAAAGGTTAAGGACTTCTGTTGCCGCTTCTGCCCGAAGAGATTCGCCAAGAAGCAATACCTGCGGCACCATGAGTACATTCACACTGGAGAGAAGCCGTACGAGTGCAAGGTGTGCGGCAAGCACTTCCGCCAGGAGCAGGTTCTCAAGACGCACATGAAGGTGCACGACAAGCCGCCCCGTCCTCCGGGCAAGCCAAAGGAGCCGACGGGACCGAAGGCGGAGAGCAGTACCACGGTGAAGCGCCAGCAGCCGAAGAACTTCGAGCAGTACCAGGATCCGGCCGCGGAACGGGCGGCGGCCACTGCTGAGCTGTTGGCCTACCAGATCGAAGAGAACGAGACCAAGCGCAAGGCGGAGGCGGAACTCCGAAAGATCCAGGAGGCGGCCTTCGAACAGCTCAACAAGCTCCAGAAGCAGACGAACACGTACGACGGCTTTTACGCCCAAAAGGCGGAGGCCGAAGGCACTTCCGTTGACGCACTGAAGCTGGATCATGTTTGA
Protein Sequence: MNEGSQYSIHTVCRTCLSTLDNAAAYDLFRVPGLAKKLCVCTSLSVEQADGFPKNLCTVCFFKLNDLHDFQKQCVDSVQKFQDMVASNAFACQTSFDVLDPSSAVADLPGEEEDNVHFDPLLNSKIEIIENEEDVFKMLESVEKEVEEVEMELEQPFGDESQDDSFESGNDNDLDADFQLNSSDDDVPLAQRSRRGSGRGSKAKAKLKAVAKRQEEEEDSEDSSSSEDSDGNPKDKPKRKRIPATERDRHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVESCRKGFTTANGLRVHVEHAHTETSAMHPCTYEGCNKSFARPVLLSFHMKRVHKVDTPQRDFPCTECEKVFRCPTALKKHMYKHTGEELPFACEICGKRFPINSVLRDHLLRHAGIKNHVCPYCGVGKTTRQEWNKHILTHTKEKKYECRQCDHASHNKQALANHVKVVHEKRKDFACQYCGKTFGKSHACKIHERSHTGEKCCECKICGKVFLFEKGLTKHLKTHEKRDLPKTQGANPLMGDGASGSSTIAKPSPHLRGRVERVDIAQLAGTVANPIPSVNLPSWSPQVNFTKKEGQHICPDCGKGFNHVSNMKLHYKVVHQKVKDFCCRFCPKRFAKKQYLRHHEYIHTGEKPYECKVCGKHFRQEQVLKTHMKVHDKPPRPPGKPKEPTGPKAESSTTVKRQQPKNFEQYQDPAAERAAATAELLAYQIEENETKRKAEAELRKIQEAAFEQLNKLQKQTNTYDGFYAQKAEAEGTSVDALKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487459;
90% Identity: iTF_00588331; iTF_00529748; iTF_00512190; iTF_00548260; iTF_00536968; iTF_00581726; iTF_00578739; iTF_00605772; iTF_00602801; iTF_00486755; iTF_00605031; iTF_00505586; iTF_00565557; iTF_00543254; iTF_00596830; iTF_00504863; iTF_00619327; iTF_00591873;
80% Identity: -