Basic Information

Insect: Drosophila melanogaster
Gene Symbol: -
Assembly: GCA_000001215.4
Location: JANZWZ010001362.1:265384-267767[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.048 5.2 8.0 5.9 3 23 255 275 253 275 0.96

2 12 3 3.3e+02 2.4 0.1 8 23 286 302 282 302 0.87

3 12 0.0019 0.2 12.5 0.7 1 23 309 334 309 334 0.94

4 12 0.84 92 4.1 0.2 8 23 336 351 335 351 0.89

5 12 6.4e-05 0.007 17.1 0.1 1 23 358 380 358 380 0.97

6 12 0.0052 0.57 11.1 0.5 1 23 386 408 386 408 0.97

7 12 0.02 2.2 9.2 1.3 1 23 414 437 414 437 0.97

8 12 0.0085 0.93 10.4 4.5 1 23 443 465 443 465 0.96

9 12 0.00024 0.026 15.3 2.4 2 23 472 493 471 493 0.96

10 12 1.1e-05 0.0012 19.5 1.5 1 23 566 589 566 589 0.96

11 12 0.031 3.3 8.6 7.1 1 23 595 617 595 617 0.94

12 12 0.011 1.2 10.1 0.8 1 12 623 634 623 636 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.048	5.2	8.0	5.9	3	23	255	275	253	275	0.96
2	12	3	3.3e+02	2.4	0.1	8	23	286	302	282	302	0.87
3	12	0.0019	0.2	12.5	0.7	1	23	309	334	309	334	0.94
4	12	0.84	92	4.1	0.2	8	23	336	351	335	351	0.89
5	12	6.4e-05	0.007	17.1	0.1	1	23	358	380	358	380	0.97
6	12	0.0052	0.57	11.1	0.5	1	23	386	408	386	408	0.97
7	12	0.02	2.2	9.2	1.3	1	23	414	437	414	437	0.97
8	12	0.0085	0.93	10.4	4.5	1	23	443	465	443	465	0.96
9	12	0.00024	0.026	15.3	2.4	2	23	472	493	471	493	0.96
10	12	1.1e-05	0.0012	19.5	1.5	1	23	566	589	566	589	0.96
11	12	0.031	3.3	8.6	7.1	1	23	595	617	595	617	0.94
12	12	0.011	1.2	10.1	0.8	1	12	623	634	623	636	0.91

Sequence Information

Coding Sequence: ATGAATGAGGAGAGCCAGTACTCCATACACACGGTGTGCCGCACCTGCCTGTCCACGGTGGACGACTCGGCGGCCTACGATCTGTTCCGAGTGCCCGGTCTGGCCAAAAAGCTGTGCGTGTGCACCTCCTTGTCCGTGGAGCAGGCGGATGGCTTTCCCAAGAACCTGTGCAATGTCTGCTTCTCCAAGCTGAACGACCTGCACGACTTTCAGAAGCAGTGCGTCGATTCCGTTCAAAAGTTCCAAGATCTGGTGGCCAGCAACGCGTTCGCCTGCCAAACAAACTTCGATGTTCTGGACACCAGTGCCGCTGTGGCGGATCTGCCGGGCGAGGAAGAGGACAACGTGCACTTCGATCCGCTGCTCAACTCCAAGATCGAGATCATTGAGAACGAGGAGGACGTCTTCAAGATGCTCGAGTCCGTCGAAAAGGAGGTCGAAGAGGTGGAGATGGAGATGGAACAGCCGTTTGGCCGAGTATCTCAGGATGACTCCTTTGAGAGCGGCAACGACAACGACCTCGACGCAGACTTCCAAATCAGTAGTGACGACGACATTCCACTGGCCCAGCGCAGCCGGCGTGGAGCCACTCGTGGTTCCAAGGCGAAGGGCAAGCCGAAGTCGGCTGCCAAGCGACAGGAGGAGGAATCCGAGGAGTCCGAGGAGACCAGCTCATCAGACGACTCCGATGGCAATCCCAAGGACAAGCCCAAACGCAAGAGGATTCCTGCTACGGAGCGGGATCGCCACCGCCTGATTGACTGCCACATCTGCCACCAGAAGTTCAAGAAGGCGATTCGCTACGAGGAGCACATGAAGCATCACAACGACTTGCTACCCTTCCAGTGCACAGTCGAGAGCTTTACCACCGCCAATGGACTGCGCGTCCATGTGGAGCACGCCCACACGGAGACATCGGCTATGCATCCGTGCACCTACGAGGGCTGCAACAAGTCCTTTGCCCGGCCCGTGCTGCTCAGCTTCCACATGAAACGCGTGCACAAGAAGGTCTTCCGCTGCCCCACTGCCCTCAAGAAGCACATGTACAAGCACACGGGCGAGGAGCTGCCCTTCGCATGTGAAATTTGCGGCAAGCGCTTCCCCATCAATAGTGTGCTGCGCGACCATCTGCTGCGCCATGCGGGCATCAAGAACCATGTGTGCCCGTATTGCGGAGTGGGCAAGACGACGCGCCAGGAGTGGAACAAGCACATCCTCACCCACACGAAGGAGAAGAAGTACGAGTGCCGGCAGTGCGACCATGCCTCCCACAACAAACAGGCGCTGGCCAACCACGTGAAGGTGGTGCACGAGAAGCGCAAGGACTTTGCCTGCCAGTACTGCGGAAAGACCTTTGGCAAGTCGCACGCCTGCAAGATTCACGAGAGAAGTCATACCGGCGAAAAGTGCTGCGAGTGCAAGATCTGCGGCAAGGTGTTCCTCTTCGAGAAGGGCCTAACCAAGCATTTGAAGACGCACGAGAAGCGTGATTTGCCCAAGACGCAGGGGACCAATGCCTTAATGGGCGACGGGGCCAGTGGATCCTCGACAATAGCCAAGCCCAGTCCGCACCTGCGTGGTCGCGTCGAGCGGGTGGACATTGCTCAGTTGGCGGGAACGGTGGCTAATCCAATTCCATCGGTCAACCTGCCCTCGTGGTCGCCGCAAGTGAACTTCACCAAGAAGGAGGGCCAGCATATCTGCCCGGACTGCGGCAAGGGCTTCAATCACGTGAGCAACATGAAGCTGCACTACAAGGTGGTGCATCAAAAGGTCAAAGACTTCTGCTGCCGCTTCTGCCCGAAGAGATTCGCCAAGAAGCAGTACCTGCGGCACCACGAGTACATACACACTGGCGAAAAGCCTTACGAGTGCAAGGTGTGCGGCAAGCATTTCCGGCAGGAGCAGCCCAAGGAGCCGGCTGGACCCAAGGCGGAGTCCAGCACCGCGGTGAAGCGCCAGCAGCCGAAGAATTTCGAGCAGTACCAGGATCCGGCGGCGGAAAGGGCAGCGGCCACCGCCGAGCTGCTGGCCTACCAGATCGAGGAGAACGAGGCCAAGCGCAAGGCGGAGGCGGAGCTCCGGAAGATCCAGGAGGCTGCCTTCGAGCAGCTAAACAAGCTGCAGAAGCAGTCGAACACTTACGACGGCTTCTACGCGCAGAAGGCGGAGGCGGAGGGCACCTCAGTGGACGCACTGAAGTTGGATCATGTTTGA
Protein Sequence: MNEESQYSIHTVCRTCLSTVDDSAAYDLFRVPGLAKKLCVCTSLSVEQADGFPKNLCNVCFSKLNDLHDFQKQCVDSVQKFQDLVASNAFACQTNFDVLDTSAAVADLPGEEEDNVHFDPLLNSKIEIIENEEDVFKMLESVEKEVEEVEMEMEQPFGRVSQDDSFESGNDNDLDADFQISSDDDIPLAQRSRRGATRGSKAKGKPKSAAKRQEEESEESEETSSSDDSDGNPKDKPKRKRIPATERDRHRLIDCHICHQKFKKAIRYEEHMKHHNDLLPFQCTVESFTTANGLRVHVEHAHTETSAMHPCTYEGCNKSFARPVLLSFHMKRVHKKVFRCPTALKKHMYKHTGEELPFACEICGKRFPINSVLRDHLLRHAGIKNHVCPYCGVGKTTRQEWNKHILTHTKEKKYECRQCDHASHNKQALANHVKVVHEKRKDFACQYCGKTFGKSHACKIHERSHTGEKCCECKICGKVFLFEKGLTKHLKTHEKRDLPKTQGTNALMGDGASGSSTIAKPSPHLRGRVERVDIAQLAGTVANPIPSVNLPSWSPQVNFTKKEGQHICPDCGKGFNHVSNMKLHYKVVHQKVKDFCCRFCPKRFAKKQYLRHHEYIHTGEKPYECKVCGKHFRQEQPKEPAGPKAESSTAVKRQQPKNFEQYQDPAAERAAATAELLAYQIEENEAKRKAEAELRKIQEAAFEQLNKLQKQSNTYDGFYAQKAEAEGTSVDALKLDHV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00487459;
90% Identity: iTF_00494575;
80% Identity: -