Basic Information

Insect: Drosophila bocki
Gene Symbol: -
Assembly: GCA_008042715.1
Location: VNJY01000667.1:170073-173671[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.012 0.89 10.0 2.6 3 23 326 347 324 347 0.95

2 17 0.22 15 6.1 0.1 1 23 354 379 354 379 0.94

3 17 0.065 4.7 7.8 4.0 2 23 390 411 390 411 0.93

4 17 0.038 2.7 8.5 0.1 3 23 452 473 451 473 0.95

5 17 0.0036 0.26 11.7 0.4 3 23 481 501 479 501 0.95

6 17 0.0049 0.35 11.3 0.2 1 23 509 532 509 532 0.98

7 17 0.0054 0.39 11.2 0.3 2 23 537 558 536 558 0.97

8 17 0.0001 0.0075 16.5 0.7 1 22 606 627 606 630 0.91

9 17 0.31 22 5.6 1.4 3 21 637 655 637 656 0.90

10 17 0.0031 0.23 11.9 0.6 1 23 675 700 675 700 0.97

11 17 0.2 15 6.2 1.3 2 23 718 740 717 740 0.93

12 17 0.0065 0.47 10.9 0.5 2 23 746 768 745 768 0.92

13 17 0.016 1.1 9.7 0.2 2 23 772 794 771 794 0.95

14 17 6.7e-05 0.0048 17.2 0.6 1 23 800 822 800 822 0.97

15 17 0.0076 0.55 10.7 0.9 1 23 826 849 826 849 0.93

16 17 1.3e-05 0.00091 19.4 1.4 1 23 855 878 855 878 0.97

17 17 3.1e-05 0.0022 18.2 0.1 4 23 885 910 882 910 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.012	0.89	10.0	2.6	3	23	326	347	324	347	0.95
2	17	0.22	15	6.1	0.1	1	23	354	379	354	379	0.94
3	17	0.065	4.7	7.8	4.0	2	23	390	411	390	411	0.93
4	17	0.038	2.7	8.5	0.1	3	23	452	473	451	473	0.95
5	17	0.0036	0.26	11.7	0.4	3	23	481	501	479	501	0.95
6	17	0.0049	0.35	11.3	0.2	1	23	509	532	509	532	0.98
7	17	0.0054	0.39	11.2	0.3	2	23	537	558	536	558	0.97
8	17	0.0001	0.0075	16.5	0.7	1	22	606	627	606	630	0.91
9	17	0.31	22	5.6	1.4	3	21	637	655	637	656	0.90
10	17	0.0031	0.23	11.9	0.6	1	23	675	700	675	700	0.97
11	17	0.2	15	6.2	1.3	2	23	718	740	717	740	0.93
12	17	0.0065	0.47	10.9	0.5	2	23	746	768	745	768	0.92
13	17	0.016	1.1	9.7	0.2	2	23	772	794	771	794	0.95
14	17	6.7e-05	0.0048	17.2	0.6	1	23	800	822	800	822	0.97
15	17	0.0076	0.55	10.7	0.9	1	23	826	849	826	849	0.93
16	17	1.3e-05	0.00091	19.4	1.4	1	23	855	878	855	878	0.97
17	17	3.1e-05	0.0022	18.2	0.1	4	23	885	910	882	910	0.84

Sequence Information

Coding Sequence: ATGTCggaaaaccagaaaaacacaaatagcTGCCTGCATTGTACTGTTTTCAATACGAAATACCAGTACCAGGAGATCTTCGATGAGTTTGGCAGGGAACTGGGCCTCCAAACGCTGCTGGCCAAGCATTTCCAGCTGGATGTGGCGCCCGATCCGCTCCAGCGTCAGCTCCTGTGCGAGGTGTGCATCAACACACTCATCCGGCTGTTTGATATCGATGAACTGCAGCGGCAACAGGATGCGGCGAGGGCTAGGCTCAAGGATTCAAGTCCTGAAACTGTTGTCATCCTGGATTCAGTCGAGCCTGAAGTTAAGCCTGcgccagctgctgccgctcccAAGAAGGAAAAGgttgttgctcctcctcctcctcccttaAGGGAACCAAGTGCACGGATCAGTAAGAGAGTTCAGCCACCTCTGGTAGTGCCTGTTCCATCTAAATCGTCGGAAAGAGCCAAGGAGACGGTCAAACCCGAAAAGGAAGCATTGCCCGCCAAGCCAAAGGATGCAGATCAGGAGCATATCAGTGTGCTCATACAAAACCTTCTTGATGAAGACGAGGTCACGAGCGAGGAAGTGGCCGACGAAGCTGAGTCCTTTTGTGAGGAAGTAGAAGCAATAGAAGCTGTTCCCATTCCAGAGGAGCCGCAAACCCAAAGGAAAATTGTCTTGTTGAACAAGAAAGCTGCGCGGCAGCCTAGTCTAGATGAAGATATTTACATATACGAGCATGAGGATATCTTGGAGCCAGCTGTAAAGAAGGTAAAGGTCGAAGTCAAGGCTCGATCTTTAGCTAAGGAACAAGTTCAAGCGGAGGAGAGCCAAAGCGAGGGTGAAACCGAGGAGAGTCATGTGGTGCTCTTTGACTTTGTTATGATCAAAGAAAAGGATGACATTGCTGACATTGCCGAGTACTTGTCCACGGTGGTAAAGACCAGCTTTGAAAAGCTAACCTTTGAATGGACCACGGCTTGCAAACACTGTTCCCAGAAGTTTCCCAACTTTGAGAGCCTTTTGAGTCACACACTAAAGTCGCATAAATCTCGAGGCAATGTCTACAAGTGTCCCATTGATGGCTGCACCAAGGAGTTGAAGGGCAGCAAATTTCTGGCCATGCATTTGGTTGTCTTACATGCTCCCGTAGCTGAAATACCCATTTATGGCAGCTGTCCGGAGTGCAAAATGactttttcaaatattttgcattacaACAAACACTCTTGTGCTCATATGATTAAAAAGAAGCGCGGTGTTCGCTTATTTTGTGAAATGTGTGCTCAGGAATTTCCCTCCTGGAAGCGTTTTAACTTTCACAATCAATTCCATTTGGAGAAGCATAGGCCTCGTGCCTGCTTTGTCTGTGATTatgccagcagcaacattgaTGAGCTGTTTCAGCACTTGAACTACTCCCATGAGCCTGTGGGCACTTTATTTTGCGACCTtTGCGATCGCACTTTTCGGGATCCCGGGGTATTCATGGAGCACAATAAGTCGCATGCCAATGTGAGCAGCACTACTTATTCTTGCGGCGAATGCATGGCAGTATTTGAGTCACGAAGTCGCCTAAATGGACACATGCGCTCTATGCATGGCAGCATTATAAGCTGCGAGCTCTGTTCCCGCGAGTTTGGCAGCGAGGCCACCTACAGCATTCACATGAAGAAGCATCTGATTATCGAGCGAGATCTGCACGTTTGCCACAATTGCGGCCTGCTGAACGATAGCCAAGAAAAGATGGCTGAACATGCAGAAACCAAGAATTCACCGTGTTTTAAGGCCAAAATATACACAGAGATGCTACGCGATGCCTATGTCTGTGAATACTGTTCCTCGTACTTTAAGCAAAAGTCCGATTTACAGGCACATCGCCAGTCGGGAATCCATAAGAATGGCTTGTTTTGGTGTCAGCCGTGTGGCAAGGATTTTCCCCACATGAAACTGTATCGCCATCACCTGCGTAACTATCAGAAATTGCGTTCGGATTCAACGCATCGTAAGCTAGAGATTTGTGTCTTCTACATGTGCGATCAGCAGGACTGCACGGAGGCCTATGTAAACTGGAACTCGTTGTACACGCACAAGCGACGCACTCACGAATCGTCGGACAAGCAGACTGAGAAGGCCTCAAAGTCTGCTCAGGATTGGATTTGCCAGTTCTGCTTAAAGGAGTGCCGCTCAAAGATGTCCTTGTCTGTTCATGTGGCTAGAAGTCATAATAATGACAACGTCTCCTGTTCCTTGTGCAATGCCTCTTATAAAAGCCAGGATGCTTTGGACAAGCACCATGCCTACTGGCATGAGCCCATCGAGTGCCCGCAATGCTTTAAGATAGTCAAAAATCGTCGAAATTACGACACTCATGTTAATGTTGTGCATTCAAACAAGAAGCGCTATGCCTGCGGTGTTTGCGAAAAGGGTTTCTATCATAAAAGCGAAATGGAGGCTCATCAAAAGCTCCATGGTCAGTTATACAGCTGCGAGCAATGCAGTTTTACCACAAGGAACAAAAAGTCCTTGTCGGTTCATGTCCTGGGTCAGCACTACAAGCGTTTTGCCTTCGAGTGCAAGGTGTGCAACAAGAGATTCGGACGTCGTCAGGGTCTGACTACGCACATACAGCGGTCTCATGGCTCCAAGTACATTTGCCGTGACTACTTTGAGGCAGGCTGCGGGCGCACCTTTGTCAGCAGTTCCCAGCTTAATGTTCATGTGCGGAAAGTCCACGAAGGCAGCATTTTTctacaggaggaggaggaggaagaagagGACAGCGATGGGCCATCCACATCCAAGAAGACCTGCTATAACATCGATGATGATAGCAATATTGAGTTTGTAGAAATTGGCGAAggcgaggatgaggaggagatggtggaggaagaggaggaagaaTTTATTGACGATCCCAATTTGGATACTAAACATTAA
Protein Sequence: MSENQKNTNSCLHCTVFNTKYQYQEIFDEFGRELGLQTLLAKHFQLDVAPDPLQRQLLCEVCINTLIRLFDIDELQRQQDAARARLKDSSPETVVILDSVEPEVKPAPAAAAPKKEKVVAPPPPPLREPSARISKRVQPPLVVPVPSKSSERAKETVKPEKEALPAKPKDADQEHISVLIQNLLDEDEVTSEEVADEAESFCEEVEAIEAVPIPEEPQTQRKIVLLNKKAARQPSLDEDIYIYEHEDILEPAVKKVKVEVKARSLAKEQVQAEESQSEGETEESHVVLFDFVMIKEKDDIADIAEYLSTVVKTSFEKLTFEWTTACKHCSQKFPNFESLLSHTLKSHKSRGNVYKCPIDGCTKELKGSKFLAMHLVVLHAPVAEIPIYGSCPECKMTFSNILHYNKHSCAHMIKKKRGVRLFCEMCAQEFPSWKRFNFHNQFHLEKHRPRACFVCDYASSNIDELFQHLNYSHEPVGTLFCDLCDRTFRDPGVFMEHNKSHANVSSTTYSCGECMAVFESRSRLNGHMRSMHGSIISCELCSREFGSEATYSIHMKKHLIIERDLHVCHNCGLLNDSQEKMAEHAETKNSPCFKAKIYTEMLRDAYVCEYCSSYFKQKSDLQAHRQSGIHKNGLFWCQPCGKDFPHMKLYRHHLRNYQKLRSDSTHRKLEICVFYMCDQQDCTEAYVNWNSLYTHKRRTHESSDKQTEKASKSAQDWICQFCLKECRSKMSLSVHVARSHNNDNVSCSLCNASYKSQDALDKHHAYWHEPIECPQCFKIVKNRRNYDTHVNVVHSNKKRYACGVCEKGFYHKSEMEAHQKLHGQLYSCEQCSFTTRNKKSLSVHVLGQHYKRFAFECKVCNKRFGRRQGLTTHIQRSHGSKYICRDYFEAGCGRTFVSSSQLNVHVRKVHEGSIFLQEEEEEEEDSDGPSTSKKTCYNIDDDSNIEFVEIGEGEDEEEMVEEEEEEFIDDPNLDTKH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00593985;
90% Identity: iTF_00527478;
80% Identity: -