Basic Information

Insect: Drosophila basisetae
Gene Symbol: zfh1
Assembly: GCA_035041595.1
Location: JAWNLB010000070.1:1301779-1307568[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.8e-05 0.0017 18.5 1.0 1 23 152 174 152 174 0.97

2 15 0.00086 0.053 13.9 1.2 3 23 182 202 180 202 0.94

3 15 9.4e-05 0.0058 16.9 0.1 1 23 369 391 369 391 0.98

4 15 0.00032 0.02 15.2 0.9 1 23 397 419 397 419 0.98

5 15 0.00012 0.0071 16.6 2.3 1 23 451 474 451 474 0.94

6 15 0.74 45 4.6 4.3 1 23 519 541 519 541 0.87

7 15 0.0042 0.26 11.7 0.4 1 23 547 570 547 570 0.98

8 15 0.027 1.7 9.1 0.4 3 19 579 595 578 596 0.95

9 15 0.00016 0.01 16.1 5.6 1 23 605 627 605 627 0.97

10 15 0.042 2.6 8.5 1.2 2 23 633 654 632 654 0.96

11 15 9.6e-06 0.00059 20.0 1.0 1 23 663 685 663 685 0.98

12 15 0.0011 0.067 13.5 0.1 3 23 693 713 691 713 0.97

13 15 5.8e-05 0.0036 17.5 0.5 1 23 719 741 719 742 0.95

14 15 0.049 3 8.3 0.4 1 23 752 774 752 774 0.97

15 15 0.00052 0.032 14.5 0.8 1 23 1281 1303 1281 1303 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.8e-05	0.0017	18.5	1.0	1	23	152	174	152	174	0.97
2	15	0.00086	0.053	13.9	1.2	3	23	182	202	180	202	0.94
3	15	9.4e-05	0.0058	16.9	0.1	1	23	369	391	369	391	0.98
4	15	0.00032	0.02	15.2	0.9	1	23	397	419	397	419	0.98
5	15	0.00012	0.0071	16.6	2.3	1	23	451	474	451	474	0.94
6	15	0.74	45	4.6	4.3	1	23	519	541	519	541	0.87
7	15	0.0042	0.26	11.7	0.4	1	23	547	570	547	570	0.98
8	15	0.027	1.7	9.1	0.4	3	19	579	595	578	596	0.95
9	15	0.00016	0.01	16.1	5.6	1	23	605	627	605	627	0.97
10	15	0.042	2.6	8.5	1.2	2	23	633	654	632	654	0.96
11	15	9.6e-06	0.00059	20.0	1.0	1	23	663	685	663	685	0.98
12	15	0.0011	0.067	13.5	0.1	3	23	693	713	691	713	0.97
13	15	5.8e-05	0.0036	17.5	0.5	1	23	719	741	719	742	0.95
14	15	0.049	3	8.3	0.4	1	23	752	774	752	774	0.97
15	15	0.00052	0.032	14.5	0.8	1	23	1281	1303	1281	1303	0.98

Sequence Information

Coding Sequence: ATGAACAATCCGAACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAGCGCCGTCGTCGACGATAGCGAATCAGAGATGACAGCAGCATATTTGGTCAACGCTGACGCCAATGGAAGCATTTCCAACGATGACGATCTCGATCATATGGCAGCCGAGAATCTCATCTTTATGGCACGCGACGGCCAACTCAGCGAAATCATCGCCGCCAATGAGGCAaatggcggcagcagcacagTGCTAATCACGGAAAGCGATGGAAATACCGGTGTCGAGTACGCCGAGTCCTTTGAAGATGATGCCCAAGTCGTCACCGAGGAGATCATCACGGATGATTGGGTCCAGCATCAGGGTGCAGAGCGagTGGAAATTGCCGCTGAGCAAATCGCTGGCAACGGCAGCTCCCAGGAGCTGTTGGACATGCAACAGAATGAGTATATGGCGATGCGTCCCTATCCCTGTGACTTTTGCAGTCGACGGTTTCGGAAGAAGGCCAGCCTCAACAATCATATGCTGGCGCATCAGAATGATCGTCCCCATCTCTGCAAGCTGTGCGGGGCGCGTTTCTCGCGTCGCGCGGAGCTCATCAGCCACTTCAAGGCGCACGCGGATGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATAAAATTtgagccacaacagcagcagcaacagcagcgacaaattGAGGATCATTTCTGTGAGCAGGAATGGCCGCTGTatcaggaacaggaacaggagcaggtcgaacagcagctggagcagatcgaggaggaggagcagcagcagcagcagttggaacagcatcagcagctgttgcaacaaTTGGTGGCACCACCAACCGCTGCCCGGGGACGCATCAGTCGCTTAAAGCTCAAGGAGGAGAGTTCGCAATATATTGTGATTGCCTCCGATAAACCTGAagcggagacggagacggagtcGCCTCAATACATGCATTGCGAGGCGAATTGCGATCAATCActtgccaccaacaacaaccaactcCAATCAACGTCCAACAATGATGTTGATGGAGCAGAGGAGCAGGGGCACGCAACGCTGCGTTTTCCCGTGCTCGACGAGAGCAAACCCTTCGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCTCTCGTCTCGCACATCAAGAATCATCGCGTCGATTCGCCGTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAACTACAGTCTACAGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAACTCGGAATATGATCCGGCATCGGCGGGCGATGAGGATACGGCAAGCGAATCCGAAGCGGAACAGCTTTACGGTAATTTCTACTGCGGCGAATGCGGCATCTCCTTTCACCGGCAGGATTTGTTGCGGCgccacagcaaacagcagcacatCAAGCAGCTgcctgcaacaacagctggtaacaacaacaacaacaacaacaacagtgtggcaactgcaacaacaacggatgcagatgcagctccaactgatgccgatgctgatgatgcCAAAGATGCGCCACATTGTTGCCACACGTGCGGCAAATCATTTCTCAGCGTACTCAAACTGCTCGCCCATACCGAAATCCACAAACGCTTCCCGCCATTCAAATGTGTCCTGTGCGGTGTCAGTTTCTACGAGGAGCAGGCCATAAAGCGGCACCTGAATACGCGGCATCCGCATGAGCTGAAGCCCAAttcgtgtgtgttgtgtggcaAGGAGTGTCGAGATCGGAAGGCGCTGATCAAACATGCGTGGGATCATTCACGGGAGAAGTGCCACTCGTGCTCCAAGTGTGGCAAGAATTTCCACAACAAGGCGCGCCTGAAACGACACATGGCATCGCATCGCGACAAGTCCGTTGTGTGCGAAGTGTGCCATGAGGAGTTCCCAGATGGACGCACCTTGTCCAATCATCGGCATTCCCATAGCACAACGTCGCCGGGCAAACTGTTTCCCTGCCACGAGTGTGGCAAGACTTTTGGGTCGCGCAGCTCGCAACAGATTCATGTGCGCATCCATACGGGTGAAAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCCGATGGCGGCACTCTCCGCAAACACGAACGCATCCACACGGGCGAGAAGCCCTATGCCTGCTCCGTCTGTCCGCGTGCCTTCAATCAGCGTGTCGTGTTGCGGGAACACATTCGGTCGCATCATTCCGCTCTGGATGCGGCACGTGGCACGTATCATTGCACGGTCTGCTCCGCGGATTTGAGCTCATCGAATGACCTCATCCAGCATCTCATCCAGCACAGTGATACGAACACAGCCAAACAGCGACAGCCAATTaCTGGTCCACGTAAATATAAACGTCGCCGGAAACTGCAGCCGCATGAGATTGCGCACATGCGCGCAGAGCACAAGGCTGGCGGGGGCGAAGGCGAGGAGGAGGATTATGGCAGCGACTTGGACTACTGCGATCTGGATGTGGAGAATGTGGATGAACTGCTGCAGGAGGCAGCCGCagagccaccaccaccagccacaaaaaaagcgaaacgcaaacgcaaagcGCCAAATAAAACCGACGATGAGCAAAGATTGTGGGATGAGAAATTCCTGCAGCAGGCGAGCAATGGGAACAGCGATGAGGCCTACAAGAATTTCTTTCAAATGGACTCGCTGGTCGTGGTCAATGATCAAACGTTGCAGCCCGTTGATGCTGGTGGTGCCACGACCAAGTTGCAGCAGGCAGAGATTAAGGAGCAAAAACTCAAAACAGTCaatcgcagcagcaaaagaaggGCAGGCAAATCTGggggaggagcagcaggaggaacAGCAGGAGTAGTagaagctgttgctgctccacGTCCCCGCATGATACACACGTCCAAGTCGCAGCAGACAACGTCAAGGAAATCCCGCACAAGGAGTTATGCCACACGCACCAGCACcaatgaacagcagcagcagcagcatcagcagccagGAGGAGGAGCAAGCCTCATCAAATCGCGCATTGTGGATGACTACGAGATCATCTCACCGGCCACACAGCCACCCAATCAGATCAGCTCCAGTCCGCTGCACATCAAACAGGAGCAGgaacatcaacagcatcatcagcaacagcagcagctgcagcatcagcagcgagTCCAACTGCTCTTCGATGACAGCCATCTGCTCATCGATGCGGGCCTGTTGCGTGAGAAGACCTACGAGAAATATAATCCCAGCATTGTCCAAGATCTCGAGGAGATTTTGCGTAGTCCTCCCAAGCATGAGCGAAACGATCGACGGCTGCGCTTCATCAGCGAATCGTCGACGACGCCACAATTTCTGCCCGGCGAGGACGAGGAACAGCATCTCATCAAGATCGAGCCAACGTCACCGGATCTACGCGAAATGGTTGAGAGCCAGCAACCAGCCACACTGTCTACATCCTCCTCCGCCGTCTGCTCAACGGCGGCACGCACTTCCCGCCACCTGCGACAGCTGACTGCCAATGGTTCCAGTTCCATTTCTACTGCCACTTCCAGTTCGAGTGCCGCTGCCAGCACGCGAGCCGCTGCCAAGCGCAATGCCAGCAAGCAGCTTGCAAAGAAATCCACTTCCAATAGCAGCAAAGCCAACTCATCATCGTCTTATCTCAGCTATGGCGTCGACTCCTAtaatgtgggcgtggcagccaGTGCCAGTGGCTCCTCGGATGTCAGTTCCGgtttcttttccatttccgAGGTCGTCTCGGCAGCGGATGCTGCCGATGCAGCTGCgaaggcggcggcggcagcagccagcaaaacgGAGCGAAGAACGCGCTGCTTTGAATGCGAAATGTGCTCGTCCAATTTTCCAGATCGCTCACAGCTGCTGGagcacatgcacatacacatctaG
Protein Sequence: MNNPNYGGIQWIQQESSAVVDDSESEMTAAYLVNADANGSISNDDDLDHMAAENLIFMARDGQLSEIIAANEANGGSSTVLITESDGNTGVEYAESFEDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNEYMAMRPYPCDFCSRRFRKKASLNNHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHADAQVAADEEAAAAAIKFEPQQQQQQQRQIEDHFCEQEWPLYQEQEQEQVEQQLEQIEEEEQQQQQLEQHQQLLQQLVAPPTAARGRISRLKLKEESSQYIVIASDKPEAETETESPQYMHCEANCDQSLATNNNQLQSTSNNDVDGAEEQGHATLRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGDEDTASESEAEQLYGNFYCGECGISFHRQDLLRRHSKQQHIKQLPATTAGNNNNNNNNSVATATTTDADAAPTDADADDAKDAPHCCHTCGKSFLSVLKLLAHTEIHKRFPPFKCVLCGVSFYEEQAIKRHLNTRHPHELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSALDAARGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGGEGEEEDYGSDLDYCDLDVENVDELLQEAAAEPPPPATKKAKRKRKAPNKTDDEQRLWDEKFLQQASNGNSDEAYKNFFQMDSLVVVNDQTLQPVDAGGATTKLQQAEIKEQKLKTVNRSSKRRAGKSGGGAAGGTAGVVEAVAAPRPRMIHTSKSQQTTSRKSRTRSYATRTSTNEQQQQQHQQPGGGASLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHHQQQQQLQHQQRVQLLFDDSHLLIDAGLLREKTYEKYNPSIVQDLEEILRSPPKHERNDRRLRFISESSTTPQFLPGEDEEQHLIKIEPTSPDLREMVESQQPATLSTSSSAVCSTAARTSRHLRQLTANGSSSISTATSSSSAAASTRAAAKRNASKQLAKKSTSNSSKANSSSSYLSYGVDSYNVGVAASASGSSDVSSGFFSISEVVSAADAADAAAKAAAAAASKTERRTRCFECEMCSSNFPDRSQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00542584;
90% Identity: iTF_00499722;
80% Identity: -