Basic Information

Insect: Drosophila atroscutellata
Gene Symbol: zfh1
Assembly: GCA_035041605.1
Location: JAWNLA010000059.1:676924-681740[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2.1e-05 0.0014 18.9 1.3 1 23 152 174 152 174 0.97

2 15 0.00089 0.057 13.8 1.2 3 23 182 202 180 202 0.94

3 15 9.6e-05 0.0061 16.9 0.1 1 23 375 397 375 397 0.98

4 15 0.00033 0.021 15.2 0.9 1 23 403 425 403 425 0.98

5 15 0.00012 0.0076 16.6 2.3 1 23 457 480 457 480 0.94

6 15 0.025 1.6 9.3 1.5 1 23 526 548 526 548 0.93

7 15 0.0043 0.27 11.7 0.4 1 23 554 577 554 577 0.98

8 15 0.028 1.8 9.1 0.4 3 19 586 602 585 603 0.95

9 15 0.00017 0.011 16.1 5.6 1 23 612 634 612 634 0.97

10 15 0.044 2.8 8.5 1.2 2 23 640 661 639 661 0.96

11 15 9.8e-06 0.00063 20.0 1.0 1 23 670 692 670 692 0.98

12 15 0.0011 0.071 13.5 0.1 3 23 700 720 698 720 0.97

13 15 6e-05 0.0038 17.5 0.5 1 23 726 748 726 749 0.95

14 15 0.05 3.2 8.3 0.4 1 23 759 781 759 781 0.97

15 15 0.0039 0.25 11.8 0.5 1 23 1294 1316 1294 1316 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2.1e-05	0.0014	18.9	1.3	1	23	152	174	152	174	0.97
2	15	0.00089	0.057	13.8	1.2	3	23	182	202	180	202	0.94
3	15	9.6e-05	0.0061	16.9	0.1	1	23	375	397	375	397	0.98
4	15	0.00033	0.021	15.2	0.9	1	23	403	425	403	425	0.98
5	15	0.00012	0.0076	16.6	2.3	1	23	457	480	457	480	0.94
6	15	0.025	1.6	9.3	1.5	1	23	526	548	526	548	0.93
7	15	0.0043	0.27	11.7	0.4	1	23	554	577	554	577	0.98
8	15	0.028	1.8	9.1	0.4	3	19	586	602	585	603	0.95
9	15	0.00017	0.011	16.1	5.6	1	23	612	634	612	634	0.97
10	15	0.044	2.8	8.5	1.2	2	23	640	661	639	661	0.96
11	15	9.8e-06	0.00063	20.0	1.0	1	23	670	692	670	692	0.98
12	15	0.0011	0.071	13.5	0.1	3	23	700	720	698	720	0.97
13	15	6e-05	0.0038	17.5	0.5	1	23	726	748	726	749	0.95
14	15	0.05	3.2	8.3	0.4	1	23	759	781	759	781	0.97
15	15	0.0039	0.25	11.8	0.5	1	23	1294	1316	1294	1316	0.98

Sequence Information

Coding Sequence: ATGAACAATCCGGACTATGGCGGCATCCAGTGGATACAGCAGGAAAGCAGCGCCGTCGTCGACGACAGCGAAGCAGAGATGACAGCAGCCTATTTGGTCAACGCTGCCGCCAATGGAAGCATTTCCAACGATGACGAGCTCGATCATATTGCAGCCGAGAATCTCATCTTTATGGCACGCGACCGCCAACTGAGCGAAATCATCGCCGCAAATGAGGCAAATGGCGGCAGCACCACAGTGCTAATCACGGAGAGAGACGGAAATAACGGAGTGGAATACGCCGAGTCCTTTGACGATGATGCCCAAGTCGTCACCGAGGAGATCATCACGGATGATTGGGTCCAGCATCAGGGCGCAGAGCGtgtGGAAATTGCAGCAGAGCAAATCGCTGGCAACGGCAGCTCCCAGGAGCTGTTGGACATGCAACAGaatcaatatatatcgatGCGTCCATATCCCTGTGACTTTTGCAGTCGACGCTTTCGCAAGAAGGCCAGCCTCAACAATCATATGCAGGCGCATCAGAATGCTCGTCCCCATCTCTGCAAACTGTGCGGGGCGCGTTTCTCGCGACGTGCGGAGCTTATCAGTCACTTCAAGGCTCATGCGGAGGCCCAGGTGGCCGCCGATGAAGAGGCAGCTGCGGCAGCCATTAAATTtgagccacaacagcagctgcaaccgctgcaacagcagcagcagcagcagcggccaaTTGATGATCATTTCTATGAGCAGGAATGGCCGCTGTATCAGGAACATGAACAGGAGCAGGTCGAGGAGCAGTTGGAGCAGatcgaggagcagcagcaacagcagctggatcAGTTTCAGCAGCGGTTGCAACATTTGGTTGCACCACCAACCGCTGCTCGTGGACGTATCAGTCGATTGAAACTCAAGGAGGAGAGCTCCCAATATATTGTGATTGCCTCCGATAAACCGGAGGCGGAGTTGCCTCAATACATGCATTGCGAGGCGAATGGCGATCAATCActtgccaccaacaacagccaagTCCAATCAACATCATCCAACGATGTGggaactgcagctgctgcagctgatgggGCAGAGGGGCAGGCAACGCAGCGCTTTCCCGTGCTCGACGAGAGCAAACCGTTCGTCTGTCAGCAGTGCGGATTGGCCTTTGCCCGCGAGAAGGCGCTCGTCTCCCACATCAAGAATCATCGCGTGGATTCGCCTTTTGAATGCAATCAGTGCCAGGAGATGTTCTGGGACAACTACAGTCTGCAGGAGCATCAGAAGACGCATCAGTTCGAGGAGAGCAATTCGGAATATGATCCCGCATCGGCGGGCGAGGAGGATACGGCGAGTGAATCGGAAGCGGAACAGCTTTACGGTAATTTTTACTGTGGAGAATGCGGCATCTCCTTTCACCGTCAGGATTTGTTGCGGCgccacagcaaacagcagcacagTAAGCAGctagctgcaacaacagctggcaacaacaacaacaacagtgtggcaactgcaacagcaacggatGCAATGGGTGCCGCagatgcaactgcaactgatgccgatgctgatgatTCCAAAGATGCGACACATTGTTGCCGCACGTGCGGCAAATCATTTCCCAGCGTACTCAAACTGCTCGCCCATGCCGAAATCCACAAACGCTTCCCGCCATTCAAATGTGTGCTGTGCGGAGTCAGCTTCTACGAGGAGCAGGCGATAAAGCGGCACCTGAACACGCGGCATCCGCAAGAGCTGAAGCCCAattcgtgtgtgttgtgtggcaAGGAGTGTCGCGATCGAAAGGCGCTGATCAAACATGCGTGGGATCATTCGCGAGAGAAGTGCCACTCGTGCTCCAAGTGTGGCAAGAATTTCCACAATAAGGCGCGCCTGAAGCGACACATGGCATCGCATCGCGACAAGTCCGTCGTGTGCGAAGTGTGCCACGAGGAGTTCCCCGATGGACGCACTTTGTCCAATCATCGGCATTCCCACAGCACAACGTCGCCGGGCAAACTCTTTCCCTGCCACGAGTGTGGCAAGACTTTTGGGTCACGCAGCTCGCAACAGATTCATGTGCGCATCCACACGGGTGAAAGGCCCTACGGTTGTCGCTACTGCTGGAAGGCCTTCGCCGACGGCGGCACTCTCCGCAAACACGAACGCATCCATACGGGCGAGAAGCCCTATGCGTGCTCCGTCTGCCCGCGAGCCTTCAATCAGCGTGTCGTCTTGCGGGAACACATCCGGTCGCATCATTCCGGTCTGGATGCGGCACGTGGCACGTATCACTGCACGGTGTGCTCGGCGGATTTGAGCTCATCGAATGACCTCATCCAGCATCTCATCCAGCACAGTGATACGAACACAGCCAAACAGCGACAGCCAATTACTGGCCCACGTAAATACAAACGTCGCCGGAAACTGCAGCCGCATGAGATTGCGCACATGCGCGCCGAGCACAAGGCTGGCGGCGGCGATGGCGAGGCtggcgaggaggaggaggattaTGCCAGCGACTTGGACTACTGCCATCTGGATGTGGAGAATGTGGATGAACTGCTGCAGGAGGCAACGGCAGAGCCACCATCACCCGCCAAAAAAGCGaaacgcaaacgcaaagcGCCAACTAAAACCGGTGATGAGCAAAGATTGTGGGATGAGAAATTCGCGCAGCAGGCGAGCAATGGGAATAGCGATGAGGCCTACAAGAGTTTCTTCCAGATGGACTCAATGGTCGTGGTCAATGATCAAACGTTGCAGCCCGTTGATGCTGGTGTTGCCTCGACCAAGTTGCAGCAGGCGGAGATTGAGAAGCAAACACTGAAGACAGGCAATCGCAGTAGCAAAAGAAGGGCAGGTAAAGCTgggggaggaggagcaggcgcaccaggaggaggaggaggagctgctgctactactgctgctgctccacgtCCCCGGATGATACACACGGCCAAGTCGCAGCAGACAACCGCAAGGAAATCCCGCACAAGGAGTTATGTCACACGCACCAGCAccaatgagcagcagcaggggggAGGAGCAAGTGGAGGAAGCCTAATCAAATCCCGGATTGTAGATGACTACGAGATCATCTCCCCGGCCACACAGCCACCCAATCAGATCAGCTCCAGTCCGCTGCACATCaaacaggagcaggaacatcaacagcatcatcatcatcatcagcatcagcatcatcagcagcagcaccagagaGTCCAACTGCTCTTCGATGACAGCCATCTGCTCATCGATGCGGGCCTATTGCGTGAGAAGACCTACGAGAAATATAATCCCAGCATTGTCCAAGATCTCGAAGAGATTTTGCGTAGTCCCCCGAAGCATGAGCGGAACGATCGACGGCTGCGCTTCACCAGCGAATCGTCGACGACTCCACAATTTCTGCCCggcgaggaggaggaacagCATCTCATCAAGATCGAGCCCACGTCGCCGGATCTCCGCGAAATGGTCGAGagccagcagccagcggcACTGCCCACATCTTCCTCCGCCTGCTCAACGGCAGCACGCACTTCACGCCACCTGCGACAACTGACTGCCAATGGTTCCAGTTCCATTTCCACTGCCACATCCAGTTCCAGTGGCGCTCCAAGTACGCGAGCCGCTTCCAGGCGCAATGCCAGCAAACAGCTCTCCAAGAAATCCActtccaacagcaacaaaggcaacgcATCATCGTCTTATCTCAGCTATGGCGTCGACTCCTAtaatgtgggcgtggcaaccaGTGCTAATAGCTCCTCGGATGTCAGTTCCGgtttcttttccatttccgAGGTCGTCTCGGCGGCGGATGCAGCCGATGCAGCTGCgaaggcggcggcggcagcagccagcaaaacgGAGCGAAGAACGCGCTGCTTTGAGTGCGAAATGTGCTCGTCCTATTTCCCAGATCGCGCCCAGCTGCTGgaacacatgcacatacacatctaG
Protein Sequence: MNNPDYGGIQWIQQESSAVVDDSEAEMTAAYLVNAAANGSISNDDELDHIAAENLIFMARDRQLSEIIAANEANGGSTTVLITERDGNNGVEYAESFDDDAQVVTEEIITDDWVQHQGAERVEIAAEQIAGNGSSQELLDMQQNQYISMRPYPCDFCSRRFRKKASLNNHMQAHQNARPHLCKLCGARFSRRAELISHFKAHAEAQVAADEEAAAAAIKFEPQQQLQPLQQQQQQQRPIDDHFYEQEWPLYQEHEQEQVEEQLEQIEEQQQQQLDQFQQRLQHLVAPPTAARGRISRLKLKEESSQYIVIASDKPEAELPQYMHCEANGDQSLATNNSQVQSTSSNDVGTAAAAADGAEGQATQRFPVLDESKPFVCQQCGLAFAREKALVSHIKNHRVDSPFECNQCQEMFWDNYSLQEHQKTHQFEESNSEYDPASAGEEDTASESEAEQLYGNFYCGECGISFHRQDLLRRHSKQQHSKQLAATTAGNNNNNSVATATATDAMGAADATATDADADDSKDATHCCRTCGKSFPSVLKLLAHAEIHKRFPPFKCVLCGVSFYEEQAIKRHLNTRHPQELKPNSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCHEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDAARGTYHCTVCSADLSSSNDLIQHLIQHSDTNTAKQRQPITGPRKYKRRRKLQPHEIAHMRAEHKAGGGDGEAGEEEEDYASDLDYCHLDVENVDELLQEATAEPPSPAKKAKRKRKAPTKTGDEQRLWDEKFAQQASNGNSDEAYKSFFQMDSMVVVNDQTLQPVDAGVASTKLQQAEIEKQTLKTGNRSSKRRAGKAGGGGAGAPGGGGGAAATTAAAPRPRMIHTAKSQQTTARKSRTRSYVTRTSTNEQQQGGGASGGSLIKSRIVDDYEIISPATQPPNQISSSPLHIKQEQEHQQHHHHHQHQHHQQQHQRVQLLFDDSHLLIDAGLLREKTYEKYNPSIVQDLEEILRSPPKHERNDRRLRFTSESSTTPQFLPGEEEEQHLIKIEPTSPDLREMVESQQPAALPTSSSACSTAARTSRHLRQLTANGSSSISTATSSSSGAPSTRAASRRNASKQLSKKSTSNSNKGNASSSYLSYGVDSYNVGVATSANSSSDVSSGFFSISEVVSAADAADAAAKAAAAAASKTERRTRCFECEMCSSYFPDRAQLLEHMHIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00542584;
90% Identity: iTF_00499722;
80% Identity: -