Dath007128.1
Basic Information
- Insect
- Drosophila athabasca
- Gene Symbol
- -
- Assembly
- GCA_008121215.1
- Location
- CM017796.1:42604592-42607845[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 4.6 3.1e+02 1.9 0.9 2 23 125 147 124 147 0.92 2 13 0.045 3 8.2 6.9 2 23 170 192 169 192 0.95 3 13 0.0004 0.027 14.6 3.1 3 23 200 221 199 221 0.97 4 13 0.0092 0.63 10.4 9.1 2 23 458 479 458 479 0.97 5 13 1e-06 7.1e-05 22.8 1.2 1 23 485 508 485 508 0.96 6 13 0.00054 0.037 14.3 0.3 1 23 513 536 513 536 0.93 7 13 5.2e-05 0.0036 17.4 5.5 1 23 554 576 554 576 0.96 8 13 0.00088 0.06 13.6 1.1 1 23 581 603 581 603 0.97 9 13 2.7e-05 0.0019 18.3 1.7 1 23 609 631 609 631 0.95 10 13 2e-05 0.0013 18.8 0.7 1 23 637 659 637 659 0.98 11 13 2.9e-07 1.9e-05 24.6 2.7 3 23 667 687 666 687 0.99 12 13 5.1e-08 3.4e-06 26.9 1.9 1 23 693 715 693 715 0.99 13 13 0.32 22 5.5 3.4 1 19 720 738 720 743 0.89
Sequence Information
- Coding Sequence
- ATGGCCGCGTCAGCCCAACCAGTGCCGGCGGGCGGTAGCTTCGATTTCGATGCTGAGATTGTCTGCCGGATTTGCCTGCGCAGTGTGGCGGTGGGCGAGGAGATGCACTTCATCTACGACGAGGCGCCTGTGGAGCAAGGAGCCAATCTCGTCCAGATACTGAACGAGTGCACGCGCTACACCTGCGACCGATTCGACGACAAGATGCCGCATAAAATGTGCGATCTGTGCATCAAGGCGGCCCGCCACGCCTACCGTTTCAAGCTTGACGCGGAAAAGTCCTATAGCTCCCTGATGGCACTGCTGGGACGCACGCTTAACAGCAGCATAACCATCGATGTGTGCACTCAAACAGATCAGGTGGCCCTCCTGCCCTGCGAAATGTGCCACGACCAGTTTCTGAACAGCCTGGAGCTGCGACTGCATCGGAATAGGGTGCACAAAACAAGAGACAGCGGCAATAGTGCTAGTCCTAGTGATGGGGGAGTGGCGGTGGTCCAGCAACTCAAGTGTAAGTTCTGCACGCAGCATTTCCCGCATCTGCGCCAGCTCCGAGCGCATCTAGCACGGTGTCATAACCAAACGGAGCGTCTTCTGTGTCCCCACTGCCAGTCACCCTTCACCCGCAGGGATCATATGCTTCGTCACATACGCAACATACACAAAAAGGAGCCAGATAGCACCTGGCCTCTGCAGGACGAGGCCACAATGCCGAGTTCTGCCGGCGATGAGCTCGTTTCGGCCGAGGTCTTGCTCAACGAGGACGAGAATGATGAGGGCGATGCCTATCTGTGCAATATCAATCCCATATCCAGCAATGAGGAAGAGGACGAGGTCAATGACGAGGCCAAGAAAGAGCTGTGGCTGCACATTAAGCCGGAGCCCTGCCTGGAAGCCGAGGATATTGATCTGAAGCTGGAAAAGAAACTCCGACGGCGGAAAGAGAAGACTGAAACCGAGGAGCGGGAAACCTCTACCGATACCGCCCCTGTCAAAGATGAACCTTTGCCCAGCACAGAACCCGCTCAGACGACGCTGCACATCAAAGAGGAAAGCCAGCCGACAGCTGGCAGCGTGGATGAGCATGAAGGACGGGATGAAGATGACTTCATAGAAGACCCTAACCAGCCCGGGGGAGAGGAGGATTTGCCTCTCAGTGATGAAGAGGAGGGGGAGGACGAAGAGCAATACGATGAGGAGAGCGACCTGGATGACGAGGACAACGATGAGGATGATGGAGAAGAGGATGATGCCCCTCCAGAAGGCGTCGACAAATCCAATATGGATGTCGTGAGTGAATATCTGAGAAAATCGAAGCCGACGAAGCGACGGCGTCGCAACAAACAGAGCAGCGAACCCAATCCGGAGAATCGCTGCGATGTCTGTCAGCGGACATTCTCCCGCCACTGCCACCTGCTGCGGCATAAGCTCTCCCACCTCGAGAAGAAGCCGCACAGCTGCCCGCAGTGCCCCAAGGCATTTGCACGCAGCGACCATCTGAAGGCCCATGTCCAGAGCCTGCACAGCAACAAGGAGCACAAATGTACCCTATGCGAGGCCGCCTTTGCTCGTCCCGAGGCTCTCGAGCGGCACAAGGTGAGCAAGCATAATGGCGAGGGCCTGGAGGCGGGCAGCGAACTGAAACTCCAACTGGCGGAGCACACTTGCGAATACTGCTCGAAGCGTTTCTCCAGCAAGACGTACCTGCGCAAGCACACGCTGCTCCACACCGATTTTCTGTACGCCTGCAAGAGCTGCGAGGAGACCTTCAAGGAGCGCCAGCAGCTGCGCGAGCATGAGAAGAGCCACACTGGGCAGCGCAATTTCCTGTGCTGCATCTGTGGCGATAGCTTTGCCCGCAACGATTACCTGCGGGTGCATATGCGGCGGCATAATGGCGAGAAGCCGTACAAGTGCCGCTACTGTGTGAAGGCCTTTCCCCGGGCCACCGATCTCAAGGTGCACGAGCGGTATCACACGGGCACCAAGCCCAATCTGTGCAATACGTGCGGCAAGAGCTTCCATCGGGCCTACAATCTAACCATCCACATGCGCACCCACACGGGCGAGCGGCCGTACAAGTGTGACCAGTGCCAGAAGAGCTTCACCCAGAGCAATGACCTCAAGGCCCACATACGTCGGCACACGGGCGAGCGGTACAAGTGTCCGCACTGCGATGCCTACTTCCTGCAGCTGTACAACATGAGGAACCACTGCCTGAGTGCCCACAACAAGCATATCGAAACGAAGACGGGTCGCCTGCAGCGTACAGGTCTCCTCGAGGATGGCACTCAATCCCATCTGACTACCGTCGTGATGCCCCCCGTTCGCTatcagtcgtcgtcgtctgggCAGGATCCCAACCAAATGGAGCCACAAATGGTGGCTGTAATGGGTACGGGGATCGAGAACTCCTCAACCACCATCATTCATAATCATTCGCCGCCAGAGCCCGCCTCGGAGTACCATGCCTCGCCCGTGACTACAGGGGCTGTGCCCACAACATCGTCATCGACCACTCTAGATGGTGCTGCCTATGCACCGGCGCCGGCTCCGCCAACGCCTGTGAATGCAGCACCATTTGGCGCCTTCAATTTCCCCCCCGTCGTTATGGCGCATCTAATGTACAATCATGCTGGTGGCAGCCAGCACAGTCAGAGCGGCAGTGAGACTGGTAAATAG
- Protein Sequence
- MAASAQPVPAGGSFDFDAEIVCRICLRSVAVGEEMHFIYDEAPVEQGANLVQILNECTRYTCDRFDDKMPHKMCDLCIKAARHAYRFKLDAEKSYSSLMALLGRTLNSSITIDVCTQTDQVALLPCEMCHDQFLNSLELRLHRNRVHKTRDSGNSASPSDGGVAVVQQLKCKFCTQHFPHLRQLRAHLARCHNQTERLLCPHCQSPFTRRDHMLRHIRNIHKKEPDSTWPLQDEATMPSSAGDELVSAEVLLNEDENDEGDAYLCNINPISSNEEEDEVNDEAKKELWLHIKPEPCLEAEDIDLKLEKKLRRRKEKTETEERETSTDTAPVKDEPLPSTEPAQTTLHIKEESQPTAGSVDEHEGRDEDDFIEDPNQPGGEEDLPLSDEEEGEDEEQYDEESDLDDEDNDEDDGEEDDAPPEGVDKSNMDVVSEYLRKSKPTKRRRRNKQSSEPNPENRCDVCQRTFSRHCHLLRHKLSHLEKKPHSCPQCPKAFARSDHLKAHVQSLHSNKEHKCTLCEAAFARPEALERHKVSKHNGEGLEAGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCEETFKERQQLREHEKSHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCQKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLEDGTQSHLTTVVMPPVRYQSSSSGQDPNQMEPQMVAVMGTGIENSSTTIIHNHSPPEPASEYHASPVTTGAVPTTSSSTTLDGAAYAPAPAPPTPVNAAPFGAFNFPPVVMAHLMYNHAGGSQHSQSGSETGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00474649;
- 90% Identity
- iTF_00471785; iTF_00536201; iTF_00574988; iTF_00580909; iTF_00517875; iTF_00473947; iTF_00484571;
- 80% Identity
- -