Dlow013103.1
Basic Information
- Insect
- Drosophila lowei
- Gene Symbol
- -
- Assembly
- GCA_008121275.1
- Location
- CM017781.1:27434586-27437518[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 4.7 3.5e+02 1.8 0.9 2 23 123 145 122 145 0.92 2 13 0.011 0.8 10.2 5.8 2 23 178 200 177 200 0.95 3 13 5.8e-05 0.0043 17.3 3.1 2 23 207 229 206 229 0.96 4 13 0.0093 0.7 10.3 9.1 2 23 473 494 473 494 0.97 5 13 1.1e-06 7.8e-05 22.8 1.2 1 23 500 523 500 523 0.96 6 13 0.00055 0.041 14.2 0.3 1 23 528 551 528 551 0.93 7 13 5.3e-05 0.004 17.4 5.5 1 23 569 591 569 591 0.96 8 13 0.0009 0.067 13.5 1.1 1 23 596 618 596 618 0.97 9 13 2.8e-05 0.0021 18.3 1.7 1 23 624 646 624 646 0.95 10 13 2e-05 0.0015 18.7 0.7 1 23 652 674 652 674 0.98 11 13 2.9e-07 2.2e-05 24.5 2.7 3 23 682 702 681 702 0.99 12 13 2.1e-08 1.6e-06 28.1 1.1 1 23 708 730 708 730 0.99 13 13 0.32 24 5.5 3.4 1 19 735 753 735 758 0.89
Sequence Information
- Coding Sequence
- ATGGCCGCCTCAGCCCAACCAGTGCCACCGGGCTGCAGCTTCGATTTCGATGCTGAGATTGTCTGCCGAATTTGCCTGCGCAGTGTGGCGGTGGGCGAGGAGATGCACTTCATCTACGACGAGGCGCCTGTGGAGCAGGGAGCCAATCTCGTCCAGATACTAAACGAGTGCACGCGCTACACCTGCGACCGATTCGACGACAAGATGCCGCATAAAATGTGCGATCTGTGCATCAAGGCGGCCCGCCACGCCTACCGTTTCAAGCGCGACGCGGAAAAGTCCTATTGCTCACTGATGGCACTACTGGGGCGCacgatcagcagcagcagcgatgtGTGCACTCAAACAGAGCAGGTGGCCCTCCTGCCCTGCGAAATGTGCCACGACCAGTTTTTGAACAGCCTGGAGCTGCGACTGCACAGGAATAGGGTGCACAAAACAAGAGACagcggcaccggcaccggcaccggcaccggcaccagcACCAATGTTAGTGCTAGTGAAGGGGTGGCGGCGGTGGTCCAGCAGCTCAAGTGTAAGTTCTGCCCGCAACATTTCCCGCATCTGCGCCAGCTCAGAGCGCATCTAGCTCGGTGTCATAACCAAACGGAGCGTCTCCAGTGTCCCCACTGCCAGTCAGCCTTCACCCGCAGGGATCATATGCTTCGTCACATACGCAACATACACAAACAAGAGTCAGACAGCACCTGGCCGCTGGAGGACGAGGCAACAATGCAGAGTTCTGCCGGCGATGAGCTCGTTTCGGCCGAGGTCTTGCTGAACGAGGACGAGAATGATGAGGGCGATGCCTATCAGTGCAATATCAATCCCATATCCAGCAATGAGGAAGAGGACGAGGTCAACGACGAGGCCAAGAAAGAGCTGTGGCTGCACATTAAGCCGGAGCCCTGCCTGGAAGCCGAGGATCTTGACCTGAAGCTCGAGAAGAAGCTTCGCCGGCGGAAAGAGAAGACTGAAACCGAGGAGCGGCAAACCTCTACCGATGCCGCCGCTGTTAAAGATGAACCTTTGCCTAGCACAGACCCAGCCCAGACGACGCTGCACATTAAAGAGGAAAGCCAGCCGGCGGCTGGCAGCGTGGATGAGCCTGAAGGACGGGATGAAGAGGAGTTCATAAAAGAACCCAGCCGCCCTGCGGGGGAGGAGGATTTGCCTCTCAGTGatgaagaggaggaggaggaggaggacgaagaGCAATACGActatggggatggggatgaggaGAGCGACCTGGATGACGAGGACAACGATGAGGATGATGGAGAAGACGATGATGCCCCTCCAGGAGGCGTGGACAAATCCAATTTGGATATCATGAGGGATTATCTGAGAAAATCCAAGCCCATAAAGCGACGACGTCGCAACAAACAGAGCGGCGAACCCAATCCGGAGAATCGCTGCGATGTCTGTCAGAGGACGTTCTCCCGCCACTGCCACCTGCTGCGGCACAAGCTCTCTCACCTGGAGAAGAAGCCGCACAGCTGCCCGCAGTGCCCCAAGGCATTTGCACGCAGCGACCATCTCAAGGCCCATGTACAGAGCCTGCACAGCAACAAGGAGCACAAATGTACCCTATGCGAAGCAGCCTTTGCTCGCCCCGAGGCTCTCGAGCGGCACAAGGTGAGCAAGCATAATGGCGAGGGCCTGGAGGCGGGCAGCGAACTGAAGCTCCAGCTGGCGGAGCACACCTGCGAATACTGCTCAAAGCGTTTCTCCAGCAAAACGTACCTGCGCAAGCACACGCTGCTCCACACCGATTTTCTGTACGCCTGCAAGAGCTGCGAGGAAACCTTCAAGGAGCGCCAGCAGCTGCGCGAGCATGAGAAGAGCCACACTGGGCAGCGCAATTTCCTGTGCTGCATCTGTGGCGATAGCTTTGCCCGCAACGATTACCTACGGGTGCACATGCGGCGGCATAATGGCGAGAAACCGTACAAGTGTCGCTACTGTGTGAAGGCCTTTCCCCGGGCCACCGATCTCAAGGTGCACGAGCGGTATCACACGGGCACCAAGCCCAATCTGTGCAATACGTGCGGCAAGAGCTTCCATCGGGCCTACAATCTAACCATCCACATGCGCACCCACACGGGCGAGCGGCCGTACAAGTGCGACCAGTGCCCGAAGAGCTTCACACAGAGCAATGACCTCAAGGCCCACATACGTCGGCACACGGGCGAGCGGTACAAGTGTCCGCACTGCGATGCCTACTTCCTGCAGCTATACAACATGAGGAACCACTGCCTAAGTGCCCACAACAAGCATATCGAAACGAAGACGGGTCGGCTGCAGCGTACAGGTCTCCTCGAGGATGGCACCCAATCGCATCTGACCACTGTCGTGATGCCCCCCGTTCGCTatcagtcgtcgtcgtcgtccggGCAGGATCCCAACCAAATGGAGCAACAAATGGGAGGCCCGGTGTCTGCAATGGGTACGGGAATCGAGAGCTCGTCAACCACCATCATTCATAACCATTCGCTGCCAGAGGCCGCCTCGGCGTACCATGCCTCGCCCGTGACCACAGGGGCTGTGCCCACAACATCGCCATCGGCCACTCTAGATGGGGCCGCCTATGCACCGGCCCCGGCACCGCCAACGCCTGTAAATGCAGCACCTTTTGGCGCCTTCAATTTTCCCCCCGTCGTTGTGGCGCATCTATTGTACAATCATGCTGGTGGCAGCCAGCACAGTCAGAGCGGCAGTGAGACTGGTAAATAG
- Protein Sequence
- MAASAQPVPPGCSFDFDAEIVCRICLRSVAVGEEMHFIYDEAPVEQGANLVQILNECTRYTCDRFDDKMPHKMCDLCIKAARHAYRFKRDAEKSYCSLMALLGRTISSSSDVCTQTEQVALLPCEMCHDQFLNSLELRLHRNRVHKTRDSGTGTGTGTGTSTNVSASEGVAAVVQQLKCKFCPQHFPHLRQLRAHLARCHNQTERLQCPHCQSAFTRRDHMLRHIRNIHKQESDSTWPLEDEATMQSSAGDELVSAEVLLNEDENDEGDAYQCNINPISSNEEEDEVNDEAKKELWLHIKPEPCLEAEDLDLKLEKKLRRRKEKTETEERQTSTDAAAVKDEPLPSTDPAQTTLHIKEESQPAAGSVDEPEGRDEEEFIKEPSRPAGEEDLPLSDEEEEEEEDEEQYDYGDGDEESDLDDEDNDEDDGEDDDAPPGGVDKSNLDIMRDYLRKSKPIKRRRRNKQSGEPNPENRCDVCQRTFSRHCHLLRHKLSHLEKKPHSCPQCPKAFARSDHLKAHVQSLHSNKEHKCTLCEAAFARPEALERHKVSKHNGEGLEAGSELKLQLAEHTCEYCSKRFSSKTYLRKHTLLHTDFLYACKSCEETFKERQQLREHEKSHTGQRNFLCCICGDSFARNDYLRVHMRRHNGEKPYKCRYCVKAFPRATDLKVHERYHTGTKPNLCNTCGKSFHRAYNLTIHMRTHTGERPYKCDQCPKSFTQSNDLKAHIRRHTGERYKCPHCDAYFLQLYNMRNHCLSAHNKHIETKTGRLQRTGLLEDGTQSHLTTVVMPPVRYQSSSSSGQDPNQMEQQMGGPVSAMGTGIESSSTTIIHNHSLPEAASAYHASPVTTGAVPTTSPSATLDGAAYAPAPAPPTPVNAAPFGAFNFPPVVVAHLLYNHAGGSQHSQSGSETGK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00474649;
- 90% Identity
- iTF_00480997;
- 80% Identity
- -