Basic Information

Insect: Drosophila arawakana
Gene Symbol: -
Assembly: GCA_018151165.1
Location: JAECWX010000405.1:491486-510038[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.87 50 4.5 1.9 3 23 280 302 278 302 0.92

2 15 2 1.1e+02 3.3 2.5 3 21 449 467 447 471 0.91

3 15 0.0087 0.5 10.8 0.7 2 23 493 515 492 515 0.95

4 15 0.064 3.7 8.0 2.4 1 23 532 555 532 556 0.95

5 15 0.14 8.1 7.0 0.2 1 21 560 580 560 584 0.91

6 15 0.0019 0.11 12.9 0.1 2 23 638 660 638 660 0.96

7 15 0.039 2.3 8.7 0.1 1 21 665 685 665 686 0.92

8 15 0.24 14 6.2 0.9 2 23 714 735 713 735 0.93

9 15 0.00021 0.012 15.8 2.8 2 23 748 768 747 768 0.97

10 15 1.7e-05 0.00097 19.3 1.8 1 23 774 797 774 797 0.96

11 15 0.00043 0.025 14.9 0.5 1 23 834 856 834 856 0.96

12 15 0.065 3.8 8.0 0.2 1 23 863 887 863 887 0.97

13 15 0.039 2.3 8.7 4.7 1 23 892 916 892 916 0.97

14 15 0.002 0.12 12.8 0.6 1 23 921 943 921 943 0.97

15 15 0.00061 0.035 14.4 5.4 1 21 949 969 949 974 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.87	50	4.5	1.9	3	23	280	302	278	302	0.92
2	15	2	1.1e+02	3.3	2.5	3	21	449	467	447	471	0.91
3	15	0.0087	0.5	10.8	0.7	2	23	493	515	492	515	0.95
4	15	0.064	3.7	8.0	2.4	1	23	532	555	532	556	0.95
5	15	0.14	8.1	7.0	0.2	1	21	560	580	560	584	0.91
6	15	0.0019	0.11	12.9	0.1	2	23	638	660	638	660	0.96
7	15	0.039	2.3	8.7	0.1	1	21	665	685	665	686	0.92
8	15	0.24	14	6.2	0.9	2	23	714	735	713	735	0.93
9	15	0.00021	0.012	15.8	2.8	2	23	748	768	747	768	0.97
10	15	1.7e-05	0.00097	19.3	1.8	1	23	774	797	774	797	0.96
11	15	0.00043	0.025	14.9	0.5	1	23	834	856	834	856	0.96
12	15	0.065	3.8	8.0	0.2	1	23	863	887	863	887	0.97
13	15	0.039	2.3	8.7	4.7	1	23	892	916	892	916	0.97
14	15	0.002	0.12	12.8	0.6	1	23	921	943	921	943	0.97
15	15	0.00061	0.035	14.4	5.4	1	21	949	969	949	974	0.93

Sequence Information

Coding Sequence: ATGCACAACGAGTCGGACGCACTGGAGGACACACATCTGTGCATCAAGTGCAATGCGACAATTGTGGGACTTGAGAAGTACATTGAGCACCGGAAGAGAAGTTGCCTGAGCGTCGCTAGAAATCAGAACCAACAGCAAAAGCAGGAGGAGAGCTCAGCAGCATCGCGTGCAACGGATCACAGCTATGATGGCTTCCATTTTACCGAGCCGGAGGCACCAAGTAGTTATCTGCGAAAGACGACAGCCAGTCATGGAGGCAAGACATCCAAGGCGCTGAGAGAGGCCTATGATCCGACCTATGACCTGGGTGCGGATCTGTTCTTCTCATCGCTGCAACTGCAGAGTGTCTCTACAGGTGGCAAGACAGTTGCGCGTCCTGAAAGAACCAAGGAGGACTCCAACTGGCATGGAAGTACCAACTGTACAGATCCGCTGCTGAAAGCGGTGCGGGAACAGGAGGAATCCGATTTTAAGCCACTGAAATTCGTGCATTCACCTGAGGCCAGTGAAGAGGAGGAAGAAGAGGATGAACCAGATGATTTCGATGACGATGATCAGGATCATGAAGCCGATGAGGACTACGACGCACGTCGTCACTCACCTCCAACTGTGCCTGCTACACACACAGGCGGCAAGTGGAAGCCCGAGCATCGTCCACAGCTACGCCACACTCACCTCGAACGACTTTCTCCTAGTTGGGATGATCCGCCGGAGGAATCACATGATCATCCACCGGCTGAGCACACACACGGCAAATGGGTGCCAGGTAGTAAACAACTGGAGTACAGGGAGAACATTGATCTGACCAAATTACAGCAACCGCGTACAAGTTATTGGTGCAACATCTGCTGCCGTCGTCTCAAGACGCGTCCTAATTACGAACAGCATCTACGCAGTGGCTACCATCAACGCCGAGCCGATGCAGAGCGTCAACTGGAGCAGGCAAATCTGGAGACTGCCAATCTCACGCTCACCAAGGACTTTCAGCACGTGGAACAGTTAGAGTCACTTCCAACTCCACTATCTCCACCGCCGCCATCTCGTCGTCGTCGTCGCCGGAATCTGCTAAGATGTGAACTCTGTCGTCACAGCATGGCCAGGCATCTGATGGGCAAGCATCTGATTTCGCACTTTCACTACCGCCGGCTGCAACAGCAGCAGACCGAAGTCCGTCGTCAGAACTCACTTCATGCCATCTTGGATCACATGGGCAGCATTGTGAGACAGGCACCTTTTCAGTGTCTGCCCTGTAAATTCTACGCCAACACGGAGCTGGCTTTTCAGATGCATTGGCGCTCCTCCGCGCATGTGAAGCTCACCGAGCGTTTGGGTGGTGATTTCTGGTGCAGCTACTGTCAGTTCGAGTGTAGCAGCAACAAGGAGATGTGGGAACATCTGCTGCATGCCACACACAAGGAAGTGCTTTTAGCTCTCAATCGATCTGTGCCCGTTTGCATTGCCCAACGACGTCGACTGCGCTGCGAGGTTTGCAATGAGAGTTTCCTCTACAATGTGCAGCTGCGACGTCACTTTGCCACCAAGCATGTTGGTATTGTGGCAACTGGCAGTGCCTCAGATGAGTACCAGTGTCGCTTTCGCTGCAACATTTGTGGCGCTGCACAGCGATCACGTGTCGCATTGCAGCGGCATGAGAAGCACAAGCATCACTTAGCGAAGTACTACTGTGCGCTCTGTGATCTGCAGTTTGATTCAGCGCAAGAGGCACGCCGTCATCGTAGTCTCGTGCAGCACGCGCGACGTCAAACGAAGCGCAAGTTTGTGGCACAACCAGAACGCGACATAGAGCACATGTTGCGTGAGGTCCTGGAGGAGGAGTCGGAGGTGGTATCTAAGGCGGAAGAGGAGGAAGAGGATGAGCCAGTGTTGGCTAAGAAGCATTGCCTAGCCCGAGAGTGCCCCAGCTGCCAGCTGAGCTTTGAGACGCCTCAGGCTCTAATCGAGCATCGTCGGCAAGTGCATCCTATGGACAATCATGCCTGTCTCAGCTGCGGCGAAAGTTTCCAGTCCGCCCAAGCTCTGGGACGCCATACACGCAGCTGTCAACCCATCGCCACCAGTACTAGATCCACAACGCTTCCCGTCTCCCCTACCGATGCAACTGCAGCCTCCAAATCCTGGCGCTGTGATCAATGCGATTTCAGTTCGATATACGAATCCGATTTACTATATCATCACATCTTTCACTCACGTGACACGGCCATTGGCAAGAACGAGCTACTTCAGTGTCCTCGTTGTCCCAAACAGTTCCGAAAGCATTCTCTGCGTGCTCATCTGCGTAATCACACAGACGAACGCATCTTCGAGTGCCAAGAGTGTCAGGCAAAGTTTGTACGTAGACACAATCTCAAAAATCACATGACAATCATACATGCAGCAAACAGAATCGAAACAACAGCAACTGCTGTCACCGCAACGCCAGCAACAACAATTGCTGTGAAGGATACTCCCAAAAAGCCAAAGAAACAGTCTACAAAGAAATTTGAGTGCGGCACCTGCGGTAAAGTTCTGACAAAAAAATTCTCCCTGCAACAACACGAACTTTTGCACACAACTACCGAGCGGCGCTTTCGCTGTCAGTTGGAGAACTGTCACTATGCGGGAATCAATGCGGAAGCTCTAAAGATTCACCTGCTCTCCCACGCCGAGGGCAGTCACAAATGTTCTCAGCCTAACTGCAAATATGTGGGCAAAAGTGAGCAGCATCTGAAGAGACACCTCAAATCGCATGTGAGCGAAACATTTGCCTGCGATCAGTGCGACTTCAGGGCCCGCATCAAAGGTCAACTTAGGCGTCATATGCTACGTCACACAGGAGAAAAGGCTCACAAGTGTCCCCACTGCGACTACCAATGCAGCACTTTTGATAATCTGCGCAAACACATCATCAAAACTGGCAAGCATCCCGGCAAGTTCATCTACGAGTGCGCCCACTGTGCAGCAACTGATCAACAAACTGCTAGCATGTTCAAGTCCAACAGCTTCAAAGAGTATCAACTGCATTTAAAAACACACAAGACTCTACATGAGTAG
Protein Sequence: MHNESDALEDTHLCIKCNATIVGLEKYIEHRKRSCLSVARNQNQQQKQEESSAASRATDHSYDGFHFTEPEAPSSYLRKTTASHGGKTSKALREAYDPTYDLGADLFFSSLQLQSVSTGGKTVARPERTKEDSNWHGSTNCTDPLLKAVREQEESDFKPLKFVHSPEASEEEEEEDEPDDFDDDDQDHEADEDYDARRHSPPTVPATHTGGKWKPEHRPQLRHTHLERLSPSWDDPPEESHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPRTSYWCNICCRRLKTRPNYEQHLRSGYHQRRADAERQLEQANLETANLTLTKDFQHVEQLESLPTPLSPPPPSRRRRRRNLLRCELCRHSMARHLMGKHLISHFHYRRLQQQQTEVRRQNSLHAILDHMGSIVRQAPFQCLPCKFYANTELAFQMHWRSSAHVKLTERLGGDFWCSYCQFECSSNKEMWEHLLHATHKEVLLALNRSVPVCIAQRRRLRCEVCNESFLYNVQLRRHFATKHVGIVATGSASDEYQCRFRCNICGAAQRSRVALQRHEKHKHHLAKYYCALCDLQFDSAQEARRHRSLVQHARRQTKRKFVAQPERDIEHMLREVLEEESEVVSKAEEEEEDEPVLAKKHCLARECPSCQLSFETPQALIEHRRQVHPMDNHACLSCGESFQSAQALGRHTRSCQPIATSTRSTTLPVSPTDATAASKSWRCDQCDFSSIYESDLLYHHIFHSRDTAIGKNELLQCPRCPKQFRKHSLRAHLRNHTDERIFECQECQAKFVRRHNLKNHMTIIHAANRIETTATAVTATPATTIAVKDTPKKPKKQSTKKFECGTCGKVLTKKFSLQQHELLHTTTERRFRCQLENCHYAGINAEALKIHLLSHAEGSHKCSQPNCKYVGKSEQHLKRHLKSHVSETFACDQCDFRARIKGQLRRHMLRHTGEKAHKCPHCDYQCSTFDNLRKHIIKTGKHPGKFIYECAHCAATDQQTASMFKSNSFKEYQLHLKTHKTLHE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00471141; iTF_00523270; iTF_00534215; iTF_00575984; iTF_00519549;
90% Identity: iTF_00471141;
80% Identity: -