Basic Information

Insect: Drosophila innubila
Gene Symbol: zag-1
Assembly: GCA_004354385.1
Location: NW:23728931-23779468[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.72 41 4.5 1.9 3 23 280 302 278 302 0.92

2 14 4.3 2.4e+02 2.1 2.1 3 21 447 465 445 469 0.91

3 14 0.0046 0.26 11.4 0.3 2 23 491 513 490 513 0.96

4 14 0.32 18 5.6 3.1 1 23 530 553 530 554 0.95

5 14 0.013 0.7 10.0 0.3 2 23 625 647 625 647 0.96

6 14 0.29 16 5.7 0.2 1 21 652 672 652 673 0.92

7 14 6.7 3.8e+02 1.5 0.6 2 20 697 715 696 718 0.86

8 14 0.00018 0.01 15.9 2.8 2 23 731 751 730 751 0.97

9 14 6.2e-06 0.00035 20.4 3.9 1 23 757 780 757 780 0.97

10 14 7.9e-05 0.0044 17.0 0.8 1 23 818 840 818 840 0.97

11 14 0.39 22 5.3 1.5 1 23 847 871 847 871 0.97

12 14 0.55 31 4.9 6.9 1 23 876 900 876 900 0.95

13 14 0.0016 0.088 12.9 0.6 1 23 905 927 905 927 0.97

14 14 0.0028 0.16 12.1 6.0 1 21 933 953 933 958 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.72	41	4.5	1.9	3	23	280	302	278	302	0.92
2	14	4.3	2.4e+02	2.1	2.1	3	21	447	465	445	469	0.91
3	14	0.0046	0.26	11.4	0.3	2	23	491	513	490	513	0.96
4	14	0.32	18	5.6	3.1	1	23	530	553	530	554	0.95
5	14	0.013	0.7	10.0	0.3	2	23	625	647	625	647	0.96
6	14	0.29	16	5.7	0.2	1	21	652	672	652	673	0.92
7	14	6.7	3.8e+02	1.5	0.6	2	20	697	715	696	718	0.86
8	14	0.00018	0.01	15.9	2.8	2	23	731	751	730	751	0.97
9	14	6.2e-06	0.00035	20.4	3.9	1	23	757	780	757	780	0.97
10	14	7.9e-05	0.0044	17.0	0.8	1	23	818	840	818	840	0.97
11	14	0.39	22	5.3	1.5	1	23	847	871	847	871	0.97
12	14	0.55	31	4.9	6.9	1	23	876	900	876	900	0.95
13	14	0.0016	0.088	12.9	0.6	1	23	905	927	905	927	0.97
14	14	0.0028	0.16	12.1	6.0	1	21	933	953	933	958	0.93

Sequence Information

Coding Sequence: ATGCAAAACGAGTCGGATGAACTGGAGGACACGCATCTGTGCATCAAGTGCAATGCGACGATTGTGGGACTGGAAAAATACATAGAACACCGCAAGAGGAGTTGCCTGAGCATTGCCAGAAGTCAGACGCAGCAGGAAAAACAGGTGGTGGCCAGAACGGCATCGGGAGCCACGGATCACAGCTATGATGGCTTTCACTTTGCGGAACCGGAGGCACCGAGCAGTTATCTGCGCAAGACGACGGCCAGTCATGGAGGGAAGACATCCAAGTCCTTGACGGAGGCCTATGATCCGACCTATGAACTGGGTGCCGATGTGTTCTTCTCCTCACTGCAACTGCAGAGTGTCTCCACGGGCGGCAAGACGAGTGCACGTCCCGAAAGGGCCAAGGAGGAGTCGAGTTGGCATGCCAGCAGCAGGTGCACAGATCCTCTGCTGAAAGCGGTGCGGGAACAGGAGGAATCTGACTTTAAGCCACTGAAATTCGTGCATTCCCCTGAGGCCagcgaggaggaggaggaggaggatgagcCAGATGAtttcgatgatgatgatcaggATCACGATGCGGACGAGGACTACGATGCACGTCGTCACTCGCCACCAGCTGTGCCGGCAACCCACACGGGCGGCAAGTGGAAGCCCGAGCATCGTCCACAGTTGCGTCACACGCATCTCGAACGCATCTCGCCCAGCTGGGATGATCCCCCAGAGGAGTCACATGACCATCCGCCAGCGGAGCACACACATGGCAAATGGGTGCCGGGCAGTAAACAGCTGGAGTACCGCGAAAACATCGACTTGACCAAGCTGCAACAACCGGGTGCAAGTTATTGGTGCAACATCTGCTGTCGTCGCCTCAAGACGCGTCCCAACTACGAGCAGCATCTGCGCAGTGGTTACCATCACCGCCGGGCGGATGCAGAGCGTCAGTTGGAGCAGGCCAATCTTGAAGGCGCCAATCTCACACTTGCCAAGGACTTCGAGCCAGTGCAGCATGTGCAGCATGTGGAGCACGTGGAGCAGCTGCAACCTCGTCGGCGTCGCCGTCGCGCCAATCTGCTGAGATGTGAGCTCTGCCGACACAGCATGGCCAGATATCTCATGGGCAAGCATCTCATCTCCCACTTTCACTATCGACgcctgcagcagcaacagacgcAGCTGCGCCGCCAGAGCTCCCTGCATGCCATCCTCGAGCACATGGGCAGCATTGTGAGGCAGGCGCCTTAGTGCCTCCCCTGTCAGTTCTATGCCAACACTGAGCAGGCTTTTCAGGTCCATTGGCGCTCCGCCTCGCATGTGGAGCTTACCGAGCGACTGGGCGGCGAATTCTGGTGCAGCTACTGTCAGTTCGAGTGTGGCAGCAACGAGCAGATGTGGCAGCATCTGTTGCATGCCACGCACCAGGAAGTGCTCCTCGCACTCAATCGCTCTGTGCCCGTTTGTATTGCACAACGTCGCCGGCTGCGTTGCGAGGTGTGCAACGAAAGTTTCCTCTACAATTTGCAGCTGCGTCGTCACTTAGCCACAGAGCATGCCGGATTGGTTGCCACAGGCAGCGCCTCGGATGAGTATCAGTGCCGCTTCCGTTGCAGCACTTGTGGCGCCGCACAGCGGTCACGTGTGGCACTGCAGCGACACGAGAAGCACAAACATCACCTGGCCAGATATTACTGTGCTCCGTGTGCCCTGGAGTTCGAGACGCCGCAAGAAGCGCGTCGGCATCGCAGCCTCGTGCAACATGCGCGACGTCTGCCGAGACGCAAGTTCGTTGCACAGCCGGAGCGTGACATTGAGCATATGCTGCGCGAGGTACTGGAGGATCAGGAGGATCAGCCCTCAGCAGCCAAGAAACGTTGCCTGGTCAGACAATGCGCCAGTTGCAAGCTTAGCTTTGAGACGCCTCAGGCGCTGGTCGAGCATCGCCGTCAGTCGCATCCCATGGACAATCATGCCTGTCTCAGCTGCGGCAGCAGCTTTCAGTCCGCCCAGGCGCTTGGTCGCCACACACGCAGCTGTCAACCCATCGCCTCCACATCGACATCTAAATCCACAGCCGACTCCAACTTAGAATCCAAATCCTGGCGCTGTGATCAGTGTGATTTCAACTCTCAATACGAGTCGGATTTGCTTTATCATGGCTTCTTCCATTCCCGTGATTCCTCCATCGGCAAGAACGAGCTTCTCCAATGTCCGCGCTGTCCCAAACAATTTCGCAAACATTCTCTTCGTGCTCATCTTCGCAATCACACGAATGAGCGCATCTTCGAGTGCAACGAGTGTCATGTCAAGTTTGCCAGGCGACACAATCTCAAGAATCACATGGCCACCATGCATGCAACAAGAAGCGCAGCAACAAACAAGTccaccgcaacaacaacaactacagcaacaacaactgcgaaGGTGACGCCCAAGAAATCAAACGGAGATAATCCCCGTAAGAAATTTCAATGCGACATTTGCGGCAAAATTCTTACCAAAAAATTCTCCTTGAAACAACATGAAATGCTTCACACTGAGGTGGTACGTCGTTTTCGCTGTCATTTTGAGGACTGTCACTATGCAGGCCTTACTCCGGAAGCTCTCAAGACCCACCTGCTCTCCCATGCCGAGGGCAGTCACAAGTGTTTACACGAAAACTGCAAGTACGTGGGCAAAAGTGAGCAGCACTTAAAGAGACACCTCAAATCACATGTGAGCGAAAAATTTGCCTGCGATCAGTGCGATTTCAGGGCCCGCATCAAGGGTCAGCTGAAGCGTCACATGCTTCGACACACGGGGGAAAAGTCTCACAAGTGCCCCCACTGCAACTTTCAGTGTAGCACTTTTGACAACCTGCGAAAACACATCATCAAAACGGGCAAGCATCCCGGCAAGTTCATCTACGAGTGTGCCTCCTGTACCGACCGACAGACAGCCAGCATCTTCAAGACCAATAGCTTCAAAGAGTATCAGCTGCATTTGAACACACATAAAACACATTCATCTGAAGTCATTtga
Protein Sequence: MQNESDELEDTHLCIKCNATIVGLEKYIEHRKRSCLSIARSQTQQEKQVVARTASGATDHSYDGFHFAEPEAPSSYLRKTTASHGGKTSKSLTEAYDPTYELGADVFFSSLQLQSVSTGGKTSARPERAKEESSWHASSRCTDPLLKAVREQEESDFKPLKFVHSPEASEEEEEEDEPDDFDDDDQDHDADEDYDARRHSPPAVPATHTGGKWKPEHRPQLRHTHLERISPSWDDPPEESHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPGASYWCNICCRRLKTRPNYEQHLRSGYHHRRADAERQLEQANLEGANLTLAKDFEPVQHVQHVEHVEQLQPRRRRRRANLLRCELCRHSMARYLMGKHLISHFHYRRLQQQQTQLRRQSSLHAILEHMGSIVRQAP*CLPCQFYANTEQAFQVHWRSASHVELTERLGGEFWCSYCQFECGSNEQMWQHLLHATHQEVLLALNRSVPVCIAQRRRLRCEVCNESFLYNLQLRRHLATEHAGLVATGSASDEYQCRFRCSTCGAAQRSRVALQRHEKHKHHLARYYCAPCALEFETPQEARRHRSLVQHARRLPRRKFVAQPERDIEHMLREVLEDQEDQPSAAKKRCLVRQCASCKLSFETPQALVEHRRQSHPMDNHACLSCGSSFQSAQALGRHTRSCQPIASTSTSKSTADSNLESKSWRCDQCDFNSQYESDLLYHGFFHSRDSSIGKNELLQCPRCPKQFRKHSLRAHLRNHTNERIFECNECHVKFARRHNLKNHMATMHATRSAATNKSTATTTTTATTTAKVTPKKSNGDNPRKKFQCDICGKILTKKFSLKQHEMLHTEVVRRFRCHFEDCHYAGLTPEALKTHLLSHAEGSHKCLHENCKYVGKSEQHLKRHLKSHVSEKFACDQCDFRARIKGQLKRHMLRHTGEKSHKCPHCNFQCSTFDNLRKHIIKTGKHPGKFIYECASCTDRQTASIFKTNSFKEYQLHLNTHKTHSSEVI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00479003;
90% Identity: iTF_00575984;
80% Identity: -