Basic Information

Insect: Drosophila acutilabella
Gene Symbol: ZNF131
Assembly: GCA_035046005.1
Location: JAWNOK010000068.1:2763088-2781010[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.83 65 4.5 1.9 3 23 280 302 278 302 0.92

2 15 0.73 57 4.7 2.4 3 22 449 468 447 471 0.91

3 15 0.043 3.3 8.6 0.5 2 23 493 515 492 515 0.94

4 15 0.061 4.8 8.1 2.4 1 23 532 555 532 556 0.95

5 15 0.049 3.8 8.4 0.1 1 21 560 580 560 584 0.91

6 15 0.00026 0.021 15.5 0.1 2 23 632 654 632 654 0.98

7 15 0.49 38 5.2 0.1 1 21 659 679 659 680 0.92

8 15 0.27 21 6.0 0.6 2 23 705 726 704 726 0.92

9 15 0.00012 0.0093 16.6 3.1 2 23 739 759 738 759 0.97

10 15 2.4e-06 0.00019 21.9 0.6 1 23 765 788 765 788 0.96

11 15 0.00041 0.032 14.9 0.7 1 23 823 845 823 845 0.96

12 15 0.32 25 5.8 0.2 1 23 852 876 852 876 0.94

13 15 0.038 2.9 8.7 4.7 1 23 881 905 881 905 0.97

14 15 0.0019 0.15 12.8 0.6 1 23 910 932 910 932 0.97

15 15 0.0017 0.13 13.0 5.6 1 21 938 958 938 963 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.83	65	4.5	1.9	3	23	280	302	278	302	0.92
2	15	0.73	57	4.7	2.4	3	22	449	468	447	471	0.91
3	15	0.043	3.3	8.6	0.5	2	23	493	515	492	515	0.94
4	15	0.061	4.8	8.1	2.4	1	23	532	555	532	556	0.95
5	15	0.049	3.8	8.4	0.1	1	21	560	580	560	584	0.91
6	15	0.00026	0.021	15.5	0.1	2	23	632	654	632	654	0.98
7	15	0.49	38	5.2	0.1	1	21	659	679	659	680	0.92
8	15	0.27	21	6.0	0.6	2	23	705	726	704	726	0.92
9	15	0.00012	0.0093	16.6	3.1	2	23	739	759	738	759	0.97
10	15	2.4e-06	0.00019	21.9	0.6	1	23	765	788	765	788	0.96
11	15	0.00041	0.032	14.9	0.7	1	23	823	845	823	845	0.96
12	15	0.32	25	5.8	0.2	1	23	852	876	852	876	0.94
13	15	0.038	2.9	8.7	4.7	1	23	881	905	881	905	0.97
14	15	0.0019	0.15	12.8	0.6	1	23	910	932	910	932	0.97
15	15	0.0017	0.13	13.0	5.6	1	21	938	958	938	963	0.93

Sequence Information

Coding Sequence: ATGCACAACGAGTCCGACGAACTGGAGGACACACATCTGTGCATCAAGTGCAATGCGACAATTGTGGGGCTTGATAAGTACATTGAGCACCGGAAGAGCAGTTGTCTGAACATTGCCAGAAATCAGaaccaacagcaaaaacaggaGGAAAGCTCAACAGCATCGCGAGCAACGGATCATAGTTATGATGGCTTCCATTTCACCGAGCCGGAGGCACCAAGTAGTTATCTGCGCAAGACGGCGGCCAGTCATGGAGGCAAGACATCCAAGGCGCTGAGGGAAGCCTATGATCCGACCTATGAATTGGGTGCGGATTTGTTCTTCTCATCGCTGCAACTGCAGAGTGTTTCCACTGGTGGCAAGACGGGTGCACGTCCTGAACGGACCAAGGAGGACTCCAACTGGCATGGAAGTACCAACTGTACAGATCCGCTGCTGAAAGCGGTGCGTGAACAGGAGGAGTCAGATTTTAAGCCTCTAAAATTCGTCCACTCCCCTGAGGCCAGTGAAGAGGAGGAAGAAGAGGATGAACCAGATGATTTCGATGACGATGATCAGGATCATGATGCCGATGAGGATTACGATGCACGTCGTCATTCGCCACCAACGGTgcctgccacacacacaggtgGCAAATGGAAGCCCGAGCATCGTCCACAGCTACGTCACACTCACCTCGAACGACTTTCTCCTAGCTGGGATGATCCGCCGGAGGAATCACATGATCATCCACCAGCGGAGCACACACACGGCAAATGGGTGCCGGGTAGTAAACAACTGGAGTACAGGGAAAACATTGATCTGACCAAGTTACAGCAACCGGGTACAAGTTATTGGTGCAACATCTGCTGTCGTCGCCTCAAGACGCGTCCCAACTACGAGCAGCATCTGCGCAGTGGCTATCATCAACGCAGAGCCGAAGCAGAGTGTCAATTGGAGCAGGCCAACCTCGAGACTGCCAATCTCACTCTTACCAAGGACTTTCAGCACGTGGAACAGTTAGAGTCACTTCCTACTCCACTTTCTCCACCGCCTCCACCTCGTCGGCGTCGTCGCCGCAATCTGCTGAGATGTGAACTCTGTCGTCACAGCATGGCTAGGCATCTGATCGGCAAGCATCTTATCTCGCATTTTCATTACCGCCGcctccaacagcagcagagccaaGTGCGTCGTCAGAACTCACTTCATGCCATCCTGGACCACATGGGCAGCATTGTGAGACAGGCACCTTTCCAGTGTCTGCCCTGTAAATTCTATGCCAACACGGAGCAGGCTTTTCAGCTGCATTGGCGCTCCTCCTCGCATGTGAAGCTCACTGAGCGTTTGGGTGGTGATTTCTGGTGCAGCTACTGTCAGTTCGAGTGTAGCAGCAATGAGGAGATGTGGCAACATCTGCAGCATGCCACACACAAGGAAGTGCTCTTGGCTTTGAATAGATCGGTGCCCGTTTGCATTGCCcagcgacgtcgactgcgctgCGAGCTGTGCAATGAAAGTTTCCTCTACAATCTACAGCTGCGCCGTCACTTTGCCACTGCGCATGTGGGTAGTGTGCCAACCGGCAGTGCCTCGGATGAGTATCAGTGTCGCTTTCGCTGCAACATTTGCGGTGCTGCTCAGCGATCACGTGTCGCATTGCAACGGCATGAGAAGCACAAGCATCACTTGGCGAGGTACTACTGTGCGCTCTGTGATCTGGAGTTTGAGACACCGCAAGAGGCACGTCGTCATCGCAGTCTAGTGCAGCACGCGCGACGCCAGCCAAAGCGCAAGTTTGTGGAACAGCCAGAACGCGACATAGAGCACATGTTGCGTGAGGTGCTGGCGGAGGAGCCGGGGGAGTTATCAAAGGCGGCAGAAGAGTCGCCTAAGAAGCTTTGCCTAACCCGACAGTGCCCCAGCTGCCAGCTGAGCTTTGAGACGCCACAGGCACTGATCGAGCATCGTCGGACAGTGCATCCCATGGACAATCATGCCTGTCTCAGCTGTGGCGGCAGTTTTCAGTCCGCCCAAGCTCTGGGACGCCATACACGCAGCTGTCAACCCATTGCCTCCAGTTCCAGCGCCACAACGCTGCCCGTTTCCTCCGCTAATGCCAGCAAATCCTGGCGTTGTGATCAATGCGATTTCAGTTCGATTTACGAATCGGATTTACTTTATCATCGCTTTTTTCACTCACGTGACTCGGCCATTGGCAAGAACGAGCTCCTTCAGTGTCCGCGTTGTCCCAAAAAGTTCCGTAAGCATTCTCTGCGTGCTCATCTGCGCAATCACACGGACGAACGCATCTTCGAGTGCCCAGAGTGTCAGGCGAAGTTTGTTCGTCGACACAATCTTAAGAATCACATGGCAATCATACATGCAGCAAacagaacaacagcagctattGTCACCGCAACACCTTTGCCAACAGTGGCTGTGCAGAATACTaccaaaaagccaaagaatCAGTCAACAAAGAAATTTGAGTGCGGCACCTGCGGTAAAGTTCTGACCAAAAAATTCTCCCTGAAACAACATGAACTTTTGCACACAACTGCCGAGCGGAGCTTTTGCTGTCAGTTGGAGAACTGTCAGTATGCGGGAATCACGGCGGAAGCTCTCAAAATTCATCTGCTCTCCCATTCCGAGGGCAGTCACAAGTGTTCTCAGCCAAACTGTAAATATGTGGGAAAAAGTGAGCAGCATCTGAAGAGACACCTCAAATCGCATAAGAGCGAAACATTCGCCTGCGATCAGTGCGATTTCAGGGCCCGCATCAAAGGTCAACTGAGGCGTCATATGCTACGTCACACGGGAGAAAAGGCTCACAAGTGTCCCCACTGTGACTTCCAATGCAGCACTTTTGATAATCTGCGCAAACACATTATCAAAACTGGCAAACATCCCGGCAAGTTCATCTACGAGTGCGACTACTGTGCAGCAACCGATCAGCAGTTCAAGTCCAACAGCTTCAAGGAGTATCAACTACATttgaaaacacacaaaaaagacTCTTCATAA
Protein Sequence: MHNESDELEDTHLCIKCNATIVGLDKYIEHRKSSCLNIARNQNQQQKQEESSTASRATDHSYDGFHFTEPEAPSSYLRKTAASHGGKTSKALREAYDPTYELGADLFFSSLQLQSVSTGGKTGARPERTKEDSNWHGSTNCTDPLLKAVREQEESDFKPLKFVHSPEASEEEEEEDEPDDFDDDDQDHDADEDYDARRHSPPTVPATHTGGKWKPEHRPQLRHTHLERLSPSWDDPPEESHDHPPAEHTHGKWVPGSKQLEYRENIDLTKLQQPGTSYWCNICCRRLKTRPNYEQHLRSGYHQRRAEAECQLEQANLETANLTLTKDFQHVEQLESLPTPLSPPPPPRRRRRRNLLRCELCRHSMARHLIGKHLISHFHYRRLQQQQSQVRRQNSLHAILDHMGSIVRQAPFQCLPCKFYANTEQAFQLHWRSSSHVKLTERLGGDFWCSYCQFECSSNEEMWQHLQHATHKEVLLALNRSVPVCIAQRRRLRCELCNESFLYNLQLRRHFATAHVGSVPTGSASDEYQCRFRCNICGAAQRSRVALQRHEKHKHHLARYYCALCDLEFETPQEARRHRSLVQHARRQPKRKFVEQPERDIEHMLREVLAEEPGELSKAAEESPKKLCLTRQCPSCQLSFETPQALIEHRRTVHPMDNHACLSCGGSFQSAQALGRHTRSCQPIASSSSATTLPVSSANASKSWRCDQCDFSSIYESDLLYHRFFHSRDSAIGKNELLQCPRCPKKFRKHSLRAHLRNHTDERIFECPECQAKFVRRHNLKNHMAIIHAANRTTAAIVTATPLPTVAVQNTTKKPKNQSTKKFECGTCGKVLTKKFSLKQHELLHTTAERSFCCQLENCQYAGITAEALKIHLLSHSEGSHKCSQPNCKYVGKSEQHLKRHLKSHKSETFACDQCDFRARIKGQLRRHMLRHTGEKAHKCPHCDFQCSTFDNLRKHIIKTGKHPGKFIYECDYCAATDQQFKSNSFKEYQLHLKTHKKDSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00479003;
90% Identity: iTF_00569324; iTF_00479003;
80% Identity: -