Danc010227.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila anceps
Gene Symbol
-
Assembly
GCA_035045945.1
Location
JAWNON010000186.1:1467964-1470489[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.085 6 7.6 4.0 1 23 276 298 276 298 0.97
2 11 1.4e-05 0.00096 19.5 0.5 1 23 304 326 304 326 0.99
3 11 0.00022 0.015 15.7 2.5 1 23 332 355 332 355 0.97
4 11 0.37 26 5.6 3.8 1 20 361 380 361 383 0.95
5 11 0.009 0.63 10.6 1.7 1 23 389 411 389 411 0.97
6 11 4.2e-05 0.0029 18.0 1.2 1 23 417 439 417 439 0.98
7 11 0.00014 0.0098 16.3 1.2 1 23 447 470 447 470 0.96
8 11 0.003 0.21 12.1 0.4 2 23 477 498 476 498 0.96
9 11 0.0019 0.13 12.8 1.2 1 23 504 526 504 526 0.98
10 11 3.4e-05 0.0024 18.2 1.2 1 23 532 555 532 555 0.96
11 11 9.5e-06 0.00067 20.0 3.4 1 23 569 591 569 591 0.97

Sequence Information

Coding Sequence
ATGTCAAAACGCACGCGCGACACCGAATCGGAGGATTTGCAAACGTATCTAAGAAATTTTCACAAAGAAATTGAGGATGGAAGTGTTGATGACAAAGAAGTCAAGGCAGATGTCGCCATGGATGATGATGCTGAAGACGATGAACAGGAAGAGAACCcggacgatgatgatgacgacaaatattttatagatgaCGAAGGTAACTGCTACATTAAAACCACTCCAAGGAAACAAGAACAGctcaaaaagaaattgaagcaacaaacaacatcgAAGGCGTCAGTCACAGAAGAAGCTGCAATCCGCAGCACTACGCGTGCGGCCAGCAGTAAAACGTCCAAAGCAATCAATCTACGTCCTGCGAAATCGAaaccagttgcagctgcaccGAGGACTCCCAAAGCAATTAATATACGACCCGCACCACCAAAAAGAACGCCAGTTAAGACAACAACTTCCACGCCAGTTAGCACACCTAGAGCATATTTACGTTCTTCAGCGAGATCTTCCAAATCTGAGCCAGAGTCGCCGCCGAAGACTAAAATAGTAATAGAGAAGATGGTGGAGTTTGAAGAACTCGTAGATGATCCGAATGTCGGTGATGTTTCCATAGACGAATCAGAGCTAACTGCCGTTGCAAATGATGCGAATACTACTAGCCTAACCGAAGATCTTAATGCGAGCAAAGAACATTCGGACAATGAGGTGTATGAGTTTGATGACAATGCTGCAAATATATCCGCTAGGTCGGATGTAGATTTCGTACTGACGGGAAATCAGTACAAGCTAAAGCCAGCGGCAACTAACTCAGCTGCATCGCAGAAGTTTGCTTGCTCCCACTGCAGCTATACAACCAATAAGAAATTCCTAATCTCACGACACGTTCGCTCCCATGATTCAGAACTGTCATTCAAGTGCTCGATCTGTGAGCGTGGCTTCAAGTCGAACATGGGACTGGTCAATcacttaaacacacacatgggcAATAAGCCGCACAAGTGCAAGCTGTGCGAGAGCGCTTTCACAACCAACGGAGAGCTTATACGCCATACACGTTACAAGCACACCAAGGAGAAGCCGCACAAGTGCACGGAGTGCAGCTATGCCAGCGTTGAACTGACAAAGCTGCGCCGCCACATGACTTGCCATACGGGCGAGCGTCCGTATCAGTGTCCTCACTGTACATATGCCTCACAGGATATGTTTAAGCTAAAGCGTCATCTGGTCATACACACGGGCGAAAAGAAGTATCAATGCGACATATGCAAGTCCCGCTTCACACAATCAAATTCACTCAAGGCACACAAACTTATTCACAGTGTGGTGGACAAACCAGTGTTTCAGTGCACCCTGTGTCCCACCACATGCGGCCGCAAGGCTGACCTGCGCACTCATATGGCCAATATGCACACCTCGGATAAGCCACTCATATGCAAGCGCTGCGGCCAGGAGCTGCCTGATCGCTATCAGTATAAGCTGCACATCAAATCACACGAAGGCGAGAAATGCTATCGTTGCAGCCTATGCAGCTATGCTTCAGTATCTCAGCGACATTTGGATTCGCATATGCTTATACACACTGATACGAAGCCGTTTAAATGCGACATGTGCTCCCAGGCGTTCCGTCAGCGTCAACTGCTGCGCCGTCATGTGAACCTGATGCACAATGAGGACTACAAGCCACCGGAGCCGCGTGAAAAGGTTCACTCCTGTCCCAGCTGTCTGCGTGTCTTCACACACAAGGGTAACCTGATGCGTCACATGGAAACCCACGACGATTCGCTAAATGCCCGCGACGAGAAGCTGAAGTTAAAACTTGGACGTAGCGTGCGTCTCCAGCCAGATGGTAGCATTGTGACTTTGGTTAATGGCTCCGACATTGAGGCACTTGACAAGACCGATACCATTTCCATTGACATCGATGACCAGTTCGAAATCACTGAATTGGAGGAGattgttgaagaagaagaagggcCTAGGGAAGTGATTGAGGAAACGTTTACTGCACCCACCTTGAGGACAagaaaagccaacaaaactGTTGTAAGAAATCGCGAGCAGAGCTCGTCCAATAAGCCAATCATTATCAATCGACAACTAAAAGCTCCGCGTGTGCACCGCGAACTAACTACTCAAGCCGGCACATTCCGCATCAAGGAAGAGCCGGATGCAAACGAATTTACAGTCGAACTTGAAGGTGAAGATGAACAGTTCATGGTCGTCCAACTGGTCAACGATGATAGCGAAGTAGTTGTCAAGCGTGAGTCCAAGATCAATGCCAATAACTGTTTTGGCTTCGAGGATGACGCCAATGTTGAATACGAAGAATATGTGGAACCTGTAGCTGAGGTGGATGCTACATCGCAGCAGTTTCTACAGCTAATGGACATGATTGAGCAGGATACATAG
Protein Sequence
MSKRTRDTESEDLQTYLRNFHKEIEDGSVDDKEVKADVAMDDDAEDDEQEENPDDDDDDKYFIDDEGNCYIKTTPRKQEQLKKKLKQQTTSKASVTEEAAIRSTTRAASSKTSKAINLRPAKSKPVAAAPRTPKAINIRPAPPKRTPVKTTTSTPVSTPRAYLRSSARSSKSEPESPPKTKIVIEKMVEFEELVDDPNVGDVSIDESELTAVANDANTTSLTEDLNASKEHSDNEVYEFDDNAANISARSDVDFVLTGNQYKLKPAATNSAASQKFACSHCSYTTNKKFLISRHVRSHDSELSFKCSICERGFKSNMGLVNHLNTHMGNKPHKCKLCESAFTTNGELIRHTRYKHTKEKPHKCTECSYASVELTKLRRHMTCHTGERPYQCPHCTYASQDMFKLKRHLVIHTGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCTLCPTTCGRKADLRTHMANMHTSDKPLICKRCGQELPDRYQYKLHIKSHEGEKCYRCSLCSYASVSQRHLDSHMLIHTDTKPFKCDMCSQAFRQRQLLRRHVNLMHNEDYKPPEPREKVHSCPSCLRVFTHKGNLMRHMETHDDSLNARDEKLKLKLGRSVRLQPDGSIVTLVNGSDIEALDKTDTISIDIDDQFEITELEEIVEEEEGPREVIEETFTAPTLRTRKANKTVVRNREQSSSNKPIIINRQLKAPRVHRELTTQAGTFRIKEEPDANEFTVELEGEDEQFMVVQLVNDDSEVVVKRESKINANNCFGFEDDANVEYEEYVEPVAEVDATSQQFLQLMDMIEQDT