Damb011945.1
Basic Information
- Insect
- Drosophila ambigua
- Gene Symbol
- Aef1
- Assembly
- GCA_018150905.1
- Location
- JAECWS010000002.1:16315648-16316696[+]
Transcription Factor Domain
- TF Family
- zf-GAGA
- Domain
- zf-GAGA domain
- PFAM
- PF09237
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.0056 43 4.1 0.1 21 46 194 219 189 221 0.87 2 4 1.6e-05 0.12 12.2 0.0 21 52 222 253 218 254 0.89 3 4 0.012 94 3.0 0.1 21 48 250 277 248 281 0.86 4 4 5.6e-05 0.42 10.5 0.1 21 47 278 304 276 311 0.88
Sequence Information
- Coding Sequence
- ATGATGCATATCAAGAGTTTGCCCCATGCTCATGCCCATGCTGCTGCCACGGCGATGAGCAGCAACTGTGACATTGTTATTGTGGCCTCTCAGCCGCAGACGACGATTGCCAACAACAACAACAATGATACGGTCACACAGGCCACTCATCCCGGTCATGTGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGGACCCCCCTCAGCGCCACCAGCTCCAGCGGAACTCGCCGCCTTACCCTTCCAAATGCATCTGAATGGGATTTCGGCCGAGGCGCATAGTGCCGCTCAGGCTGCAGCCATGGCGGCTGCTCAGGCCGCAGCAGCTCAAGCAGCGGCGGCGGATCAACATCAGCCACCGCCAGCGCCACCACCGCATCTGGTACATCTGTCCACGCACAGCCCGACCATGTCGAATGATCACTATTTGGCCAATGGCCATGGCGAGCACCAGGGTGAGGGGGCTGGCAGTAATGGAAACTCTGGCGGTGGCGGAGGCGGTGGCGCGAGAGACCAGGAAAAGCCGTTCCACTGCACCGTGTGCGATCGACGCTTCCGGCAGCTGAGCACACTGACCAACCATGTCAAGATCCACACTGGCGAGAAGCCCTACAAATGCAACGTTTGTGATAAGACCTTCCGTCAATCGTCCACGCTGACGAACCATCTGAAGATCCATACGGGGGAAAAGCCCTACAACTGCAACTTCTGTCCCAAGCATTTCCGTCAGCTGAGCACTCTGGCGAATCATGTCAAGATCCACACGGGTGAAAAGCCGTTCGAGTGCGTCATATGCAAAAAGCAATTCCGGCAGTCCAGCACGCTCAACAACCACATAAAGATCCACGTCATGGACAAGGTCTACGTTCCTGTCAAGATCAAAACGGAGGAGGAGGAGGGGTGA
- Protein Sequence
- MMHIKSLPHAHAHAAATAMSSNCDIVIVASQPQTTIANNNNNDTVTQATHPGHVXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGPPSAPPAPAELAALPFQMHLNGISAEAHSAAQAAAMAAAQAAAAQAAAADQHQPPPAPPPHLVHLSTHSPTMSNDHYLANGHGEHQGEGAGSNGNSGGGGGGGARDQEKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPYNCNFCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEEEG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00539316;
- 90% Identity
- iTF_00474726;
- 80% Identity
- iTF_00474726;