Dald006674.1
Basic Information
- Insect
- Drosophila aldrichi
- Gene Symbol
- -
- Assembly
- GCA_035045965.1
- Location
- JAWNOM010000253.1:291060-294852[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.00086 0.064 13.8 1.2 1 23 208 231 208 231 0.97 2 12 1.5e-05 0.0011 19.3 2.0 1 23 236 259 236 259 0.96 3 12 0.0003 0.022 15.2 4.6 1 23 264 286 264 286 0.98 4 12 4.9 3.6e+02 2.0 4.5 2 23 293 316 292 316 0.89 5 12 0.00045 0.034 14.7 1.0 3 23 326 347 325 347 0.95 6 12 0.0035 0.26 11.9 0.1 1 23 353 376 353 376 0.95 7 12 0.075 5.5 7.7 0.3 5 23 392 411 387 411 0.90 8 12 2.8e-05 0.0021 18.5 0.4 1 23 441 463 441 463 0.98 9 12 1.4e-05 0.001 19.4 5.3 1 23 469 491 469 491 0.96 10 12 8.4e-06 0.00062 20.1 0.1 2 23 498 519 498 519 0.97 11 12 0.0011 0.084 13.4 0.9 1 23 526 548 526 548 0.99 12 12 0.00033 0.025 15.1 3.9 1 23 554 577 554 577 0.98
Sequence Information
- Coding Sequence
- ATGGAAACGTGTCGCACCTGTGCAAGGTGCGATTTCGAAAATGGCAACAACTATTGGCTGGATATGTTTCATCCAACGCGCTGGCAGAGTGAAATGGCACAAATTCGCACAGAGTTTGTCAACTGGAAGTTACAGaTCTCTCCAAACGATGGACTCCCTCAAAAAATTTGTAGCGATTGCTTTACAAAGTTCTGTTCCGTTTACACGTTTCGCATGGCTTGCCAGGACGCACAATTAAAGCTTTcgaatatttttgataaaatCGATGCTAACTTACTGTATGATAGAAATGAAGAAAGCATTGAAGTTGATGCTGATGGTTCAGAAGCTACAACGAAAATATGCACAGTAgtagaaacagcaacaacaacgacaacaacagagaACACTGCCATTAATGCGGCCAAATCGCCCGCGCCCATTGAAATCTTTGTGGAAACCATTAGCATTAATGAAAGCGAATCCTTGCAGCcagaaaataaagaagttGACTTAGGCTCAGATTGTAATTCATTGAACATAAGCTATGCTTGTAAGTTCTGTTATAAGCCGCAAGAAAGCTACGAGCTACAGCACTTGTTACTAGAGCACATTAGCGTCTGCCACGATCCAGATCAACCCTATAACTGCCCGGAGTGCACTGAATGTTTTCAAGACACAGCATCGCGTACCGTCCACATGAAGAGCGTTCATGTGGTCAAGCACTATGCCTGTGAAGTTTGCGGCAAAAAGTATGGAGACCGCCATAATCTCGAGCATCACATTGAGAAGTATCACTCGGACACGGACTTCGAGTGCAGCATGTGCGAGAAGCGATTTTTTACGCGCAAAAGCCTGCACTACCACATGAACTGGCACAAGCCGGAGCGCCAGCTCCGATGTCGTCACAACGGCTGTGACCGGCTGTTCATCAATCAACGACATCTCATATGTCACGAGGCCACCCACACAAAGGGCTCCCGTAAGAGCGAGTACTGTGGCTTTTGTGGTAAAGCATTCATACATGTAAAAACTCTTCGTTGGCATATCTATCGACAGCATGGCGGAGAGAAGCCTTTCAAATGCGCCATCTGCACTGAGGTGTTTGCCTCCTATGTGGAGAAGCGCATTCATATGCTTGAGCTGCACACGGAAAATCTGACGCATCAGGAGCGTAGCGAGTGTATGTTTCAGTCCTGTCGCCAGGAGTTCGATACGGAGCAGGAGCTCATCCAACATATGACCACGGAGCATGCTCAGCGTGAAACTTCCTCAGCTCCGATCATTGCGAACAATAAGCGAGTGATCCAATGCAAAAGGGAACGACAATATACGGGTCTCTTCCAGTGCGGCAGCTGCACGCAACGTTTCAACATGAAATCCGCCTTGGAGCGTCACATGGCTGTCCACTCAACGGATCGGCTGCATGCCTGTTCGCACTGCTCCAAGCGCTATAAGCGTGCTCAGGATCTGAAGTGGCATATGAAGACccatgcaaatgaaaagccaAATGTGTGCGATGTATGCGGCAAGGCTTTTGCCTTGAAATATGTCCTAACTCAGCATATGCGCAGTCATGAGGttCTTGAGAAGAATTTCAAGTGTGAGACCTGTGGACGGGCGTATCTGTTTGAAAAGTCATTACGGTTGCATCAACGTGTACACACAGGCAATACCTACTATAAATGCGATCTGTGCCAAGAGCGATTTGTCACTCAcatcaaatttaaaaCTCACATGAAGAAGGCACATGATGGCGACCAGTTGCACTCTAAGGATACGCTGGATGATTTGATCAATATTGTGATTAACTAA
- Protein Sequence
- METCRTCARCDFENGNNYWLDMFHPTRWQSEMAQIRTEFVNWKLQISPNDGLPQKICSDCFTKFCSVYTFRMACQDAQLKLSNIFDKIDANLLYDRNEESIEVDADGSEATTKICTVVETATTTTTTENTAINAAKSPAPIEIFVETISINESESLQPENKEVDLGSDCNSLNISYACKFCYKPQESYELQHLLLEHISVCHDPDQPYNCPECTECFQDTASRTVHMKSVHVVKHYACEVCGKKYGDRHNLEHHIEKYHSDTDFECSMCEKRFFTRKSLHYHMNWHKPERQLRCRHNGCDRLFINQRHLICHEATHTKGSRKSEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCAICTEVFASYVEKRIHMLELHTENLTHQERSECMFQSCRQEFDTEQELIQHMTTEHAQRETSSAPIIANNKRVIQCKRERQYTGLFQCGSCTQRFNMKSALERHMAVHSTDRLHACSHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKAFALKYVLTQHMRSHEVLEKNFKCETCGRAYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKAHDGDQLHSKDTLDDLINIVIN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00502704;
- 90% Identity
- iTF_00573493;
- 80% Identity
- -