Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.97 1.2e+03 1.1 0.2 18 45 11 38 8 45 0.84

2 9 1.8 2.3e+03 0.2 0.1 25 48 46 68 37 73 0.72

3 9 0.45 5.6e+02 2.2 0.1 21 43 70 92 66 98 0.87

4 9 0.12 1.5e+02 4.0 0.2 21 44 98 121 92 125 0.88

5 9 5.3e-05 0.067 14.8 0.0 20 47 182 209 175 214 0.87

6 9 1.1 1.4e+03 1.0 0.0 21 43 211 233 209 241 0.85

7 9 0.067 84 4.8 0.1 18 46 239 267 232 273 0.84

8 9 0.0067 8.4 8.0 0.3 21 44 298 321 293 325 0.91

9 9 0.0067 8.5 8.0 0.2 20 43 325 348 323 356 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.97	1.2e+03	1.1	0.2	18	45	11	38	8	45	0.84
2	9	1.8	2.3e+03	0.2	0.1	25	48	46	68	37	73	0.72
3	9	0.45	5.6e+02	2.2	0.1	21	43	70	92	66	98	0.87
4	9	0.12	1.5e+02	4.0	0.2	21	44	98	121	92	125	0.88
5	9	5.3e-05	0.067	14.8	0.0	20	47	182	209	175	214	0.87
6	9	1.1	1.4e+03	1.0	0.0	21	43	211	233	209	241	0.85
7	9	0.067	84	4.8	0.1	18	46	239	267	232	273	0.84
8	9	0.0067	8.4	8.0	0.3	21	44	298	321	293	325	0.91
9	9	0.0067	8.5	8.0	0.2	20	43	325	348	323	356	0.88

Coding Sequence: ATGCGCGGACATCTGAAGCTGCACATGTTAAGGCACAGCAACGAGCAACTGCTCAGGTGTACTCTTTGCAATTTCAAGTGCAGGGCAGCCAAAAAATTGGAAGCGCACGTGTCAAAGCACGGCAGTGCGAAGTGGTTCAGTTGCAATCTCTGCGAATACAAATCCCAATTTACCGTAGATTTAAGGCGACACATGTTGAAGCACaacgacgagaaaccgttcaaaTGTGACCTTTGCGGTTACAGCTGTCGAAGTGCGGGGAGATTGAGGGAGCATAGGTTAACACACACCGTTGAGAAACCAGTCGGTTGTAAACTTTGCGATTATACGTGCCGAAGGCGTGAggatttgaaacagcacatgttTATACACACCGACCCCGAAAAGTGGTTGAGCTGTGacgtttgcgattataagtgtcCACGTTCCAGCACTATGAACCAtcacaaattaacacacactGGCGAGATGCGGTTCAGTTGTAGCCATTGCGAATACAAATGCCTACAGCGATTCCAACTGAAGCGGCACGTGTTAACACACAGcagcgagaagccgttcacttgCGTAATTTGCGATCGTAAAGTGAAAGAACTCGGAAATTTGAAGCGCCACATGTTgatacacaccggcgaaaagccgttcagctgcgatctttgcgattacaagtgtcgaTTCGCCACGTATTTAAAGAAACATAAATTGACACATTCTAGTGACGGCGCCGAGAAGCCGTTCGCTTGTAACAGTTGTAGTTACAAAAGCCTGACTCTCCGGAATTTAACTCGGCACATGGCAGtgcataccggcgagaagcggTTCAgctgtgacctttgcgattataaatcgCGAAGAAATGGAGATCTGAAAGACCATAAGTTAATACATACTGGTGAAAAACCGTTTGCTTGTGGcgtttgcgattacaagtgccggCACCGTTCAAATTTGAGACAGCACATGTTAACTCACCAGAGCCAGAAATCGTTTACCTGTGGAATCTGCGATTTCACAGCCCGACGACACTCAAGCTTGAAAAGACATGACATGACCCACCGACAGAAAACTTCGTTGTAA
Protein Sequence: MRGHLKLHMLRHSNEQLLRCTLCNFKCRAAKKLEAHVSKHGSAKWFSCNLCEYKSQFTVDLRRHMLKHNDEKPFKCDLCGYSCRSAGRLREHRLTHTVEKPVGCKLCDYTCRRREDLKQHMFIHTDPEKWLSCDVCDYKCPRSSTMNHHKLTHTGEMRFSCSHCEYKCLQRFQLKRHVLTHSSEKPFTCVICDRKVKELGNLKRHMLIHTGEKPFSCDLCDYKCRFATYLKKHKLTHSSDGAEKPFACNSCSYKSLTLRNLTRHMAVHTGEKRFSCDLCDYKSRRNGDLKDHKLIHTGEKPFACGVCDYKCRHRSNLRQHMLTHQSQKSFTCGICDFTARRHSSLKRHDMTHRQKTSL

Sequence clustering based on sequence similarity using MMseqs2