Basic Information

Gene Symbol
-
Assembly
GCA_958336345.1
Location
OY284475.1:3486826-3488724[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.00018 0.017 17.0 2.0 1 23 48 70 48 70 0.98
2 21 0.0011 0.1 14.5 3.8 2 23 77 98 76 98 0.96
3 21 0.013 1.2 11.2 4.6 2 23 105 126 104 126 0.96
4 21 0.95 88 5.3 1.7 3 23 134 155 132 155 0.94
5 21 0.28 26 7.0 0.9 2 23 162 183 161 183 0.95
6 21 0.23 22 7.2 1.7 2 23 190 211 189 211 0.96
7 21 0.031 2.9 9.9 1.1 1 23 217 239 217 239 0.97
8 21 0.0008 0.074 15.0 1.0 1 23 245 267 245 267 0.95
9 21 0.0048 0.44 12.5 3.6 1 23 273 295 273 295 0.97
10 21 0.00039 0.036 15.9 0.6 1 23 301 323 301 323 0.97
11 21 0.0016 0.14 14.0 5.7 1 23 329 351 329 351 0.97
12 21 0.14 13 7.9 7.2 1 23 357 379 357 379 0.97
13 21 1.7 1.6e+02 4.5 2.4 2 23 386 407 385 407 0.95
14 21 0.0017 0.16 13.9 2.5 1 23 413 435 413 435 0.97
15 21 0.013 1.2 11.1 5.0 1 23 441 463 441 463 0.97
16 21 0.0022 0.2 13.6 4.1 1 23 469 491 469 491 0.98
17 21 0.87 81 5.4 8.7 5 23 500 518 497 518 0.95
18 21 0.016 1.5 10.9 7.1 1 23 524 546 524 546 0.97
19 21 0.37 34 6.6 0.8 3 23 554 574 552 574 0.97
20 21 1.1e-05 0.00097 20.9 1.2 1 23 580 602 580 602 0.97
21 21 0.0023 0.22 13.5 3.6 1 23 608 630 608 630 0.97

Sequence Information

Coding Sequence
ATGGAAGTTGCACATATCCTTCCACATGTCCATCATGTCAGCTGCGTACCGCACAACCAATTCGTTAAAATCCGTTATTACAGTCAGTTTCGTTTCAGGTGCCAACGAGCTTCCAAATCGAGAATTCCGAGGAAGAAGACATTCGAATGTCGTCTATGCGGTTCTAATTTCAAAGCTCAAGGACATTTAAAAAAGCACATGCTGAGTCACACCGGCGACAAGCTGCTCAGGTGCGTCGTTTGCAATTACGAATGTCGACGTCCCTCCCATTTACTGCAGCACATGTACAAACACACCGACGGGAAGTCGCTCAAGTGTGACTTCTGCGATTACGAATGCAAACGGCTGCAGCATTTGAAGCAGCACGTGTCCATCCACaacgacgagaagccgttcggttgtagcttttgcgattataaatcgCACGGAAACGAACTTTTAAAACGACACGTTATGCTAAGACACACCCGAAAGAAGTCGTTGAACTGCGGCGTCTGCGGTTACAAAAGTCGAGGCAAAAATGAAATGAGGCAACATAAGTACAAGCACACGGTCGAGAAGCCATTgcgttgtgacctttgcgattacgaATGCCGACAGGGCCTATCCTTGAGAGTGCACAAGTTGAAACACGCGGGCGAGTTGCCGTTTAGCTGCGACTTATGCGATTACAAATGCGGATTGGCCGGGCAACTGAAACAGCATaagttaatacacaccgacgagaagccttTCGCTTGcgatctctgcgattacaagtgccgacAGGCCGCCAACTTGAGACAGCACAGTTTAATACACagcggcgagaagccgttcgcttgcgacctttgcgattataaatgccgacagctccAACATTTGAAAGAGCACCTGTCAATCCACAGCGATGTGAAGCCGTTCGCttgcgacctttgcgattacaagtcgCAACGAAGCGAACTTTTGAAACGACACATATTAACGCACACCGAGGAGAAATCGTTCAGCTGTGGCCTCTGCGGTTACAAGTGCCGATTTAAAAGCGACCTGAAGCGACACAGGTACAAACACACGGGGGAAAAGCCGTTCTGCTGCGATCTCTGCGATTACCAGTGCCGACAGAGCAGGTCTTTGAAGCTGCACAAGTTGAAACACGCGGACGAGCTGCCGCTTAACTGCGATCTATGCGATTACAAGTGCGGACTGGTCAGACAgttgaagcagcacaagttaaaacacaccgatgagaagccgttcgcttgcgatctttgcgactaTAGGTGCCGACAGGTCGGGAacttgaagcagcacaagtCAACGCACatcggcgagaagccgttcgcttgtgatctttgcgattacaagtgcgaGCGACTCCAACATTTGAAACAGCATTTATTCACCCACACGAgtgagaagccgtttagttgtagtctttgtgacTATAAGTGTCAACGAAATGAATCTTTGAAGCGACACGTGTTGAAGCACGACCGGGAGAATTCGTTCAAGTGCCACTGCGGTTACGCGTGTCGATTTAAGAGCGATCTGAAGCGGCACAAGCACAAGCACGCGGTCGAGAAGCAGTTCTGCTGCGAGCTTTGCGATTACACGTGCCGACAGAGCAGGTCCTTGAAACTGCACAGGTTGAAGCACTCGGGCGAGTTGCCGTTTGGCTGCGATCTCTGCGATTACAGGTGCGGGCTAGCCAGGCAATTGAAAGTGCACGCTTTgaaacacaccgacgagaagcccttcgcttgcgatctttgcgattataagttcCGAAAGGCCGGTAACTTGAAGCGACACAAGTTAACGCACAGCGGCGAGAAACCGTTTGCGTGCGACCTTTGCGATTGCAAGTACCGAAAACGCCAAAGTTTGATACGGCATAGGTTAACGCACACTCAGTAG
Protein Sequence
MEVAHILPHVHHVSCVPHNQFVKIRYYSQFRFRCQRASKSRIPRKKTFECRLCGSNFKAQGHLKKHMLSHTGDKLLRCVVCNYECRRPSHLLQHMYKHTDGKSLKCDFCDYECKRLQHLKQHVSIHNDEKPFGCSFCDYKSHGNELLKRHVMLRHTRKKSLNCGVCGYKSRGKNEMRQHKYKHTVEKPLRCDLCDYECRQGLSLRVHKLKHAGELPFSCDLCDYKCGLAGQLKQHKLIHTDEKPFACDLCDYKCRQAANLRQHSLIHSGEKPFACDLCDYKCRQLQHLKEHLSIHSDVKPFACDLCDYKSQRSELLKRHILTHTEEKSFSCGLCGYKCRFKSDLKRHRYKHTGEKPFCCDLCDYQCRQSRSLKLHKLKHADELPLNCDLCDYKCGLVRQLKQHKLKHTDEKPFACDLCDYRCRQVGNLKQHKSTHIGEKPFACDLCDYKCERLQHLKQHLFTHTSEKPFSCSLCDYKCQRNESLKRHVLKHDRENSFKCHCGYACRFKSDLKRHKHKHAVEKQFCCELCDYTCRQSRSLKLHRLKHSGELPFGCDLCDYRCGLARQLKVHALKHTDEKPFACDLCDYKFRKAGNLKRHKLTHSGEKPFACDLCDCKYRKRQSLIRHRLTHTQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00465325;
90% Identity
iTF_00465325;
80% Identity
iTF_00467117;