Dang022415.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ditula angustiorana
Gene Symbol
-
Assembly
GCA_963691745.1
Location
OY829493.1:8301094-8320427[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 6.6e-16 3.2e-12 46.6 0.0 7 70 199 260 195 265 0.87

Sequence Information

Coding Sequence
ATGTCCGAGGAAATGGCGGTTAGTGATAACCCAACTGGGGAAGAAAGTGTAGTTAACGGGGGAGAGGCGTCTGCAGCGAGTGCCGAGGACGCGGCGCCAGCGGCGCCCGAGCCGCCGAGCCAGCCCGCGAGCGAGGAGCCCGAGGACATCACACCAGATGCCGAACCTGCACCAAATGAAGAACCTGTAGCTGATGTTGAAGTTAAAGTAGAACCAATAGATGAAGGTGATAAGAGGGGCACCAAGCGCAGAGCCTCCGCCGCCTTCAGTGATGTTGCCGATGAGGATTTCAAGGGCTTCGCTAAGATGGAACTAGATGATTCCACTCTAGACTATAAACGAGTTCTAGAAAACCTTGAGGCTGAGGTGACGGAAGCCAGCAAGACAGTGGTGCCTCTGCAAACTGTGATGGGGACGCCTTTGGGACCAGTAAGGGCTAGCAAGCGAGCCAGGCAAGACACTGaTGGTTCGAGACCCTCGTCAGCGCTGTCCTCAAGATCAGATGGTGATGGAGCCATTTCTTCAACTGAgGTGAGCAGCTCGTCCCCggcggtgcgcgggcggcgcgccacGACGGAGATGTCATCCCCGCTGCTTCGCGTGCCGCTCGAGCGCGGCTGGAAGCGCGAGCTCGTGTTCCGCGCCGCGCTCGACCAGCACTCGCGCAGGAACGCCGACATCTACTACTACACCCCGCAGGGCAAGAAGCTGCGCTCCACTAGAGAGGTATCAGAACACCTCTCTGGCACTGGACTTACAATAGAGAACTTTTCATTCTTCAAGGAACCACTGGGTGTGGACGACCCTGATAAAGAAATTATTCGAGATGCGAAGATGATGCGGCGGGTGGAGTCTCCAGTGGCGCAGGCGCCGCCCCCGACGGAGGGCAAGCGCACGCCGAAGCCCAAGCAGCCCAAGGGCGCCAGCCCCGAGCCGCAGACTCCCAAATCAGCTCCAACCAAAATTAAGGTGAAGTCGATAGGTTCGCGGCTGAGCAACAGCGCGGCGCCCACGCCGCCAGCCAAGCCCAAGAAGGCTCCGGCCGCGGACAACAACAACAGCGCCGCCTGGAAGAAGAACAGaacggcgcccgcgccggccgcgccgcccgcgccgccgccgccgctgctcagccgcccgcccgccgcgccgcccgccgccggaCCAGTGCAGCGCGACGAGCCGGCGCGGCCGCAACTGGTGCAGCCGTGCTCGATGACGTGCGGGCGCGGCGTGCCGACGCTGGCCTGCGCCGCCTGCCTGTGTCTCTACCACCCCGCCTGCGCCGGGCACACCACGGCGCCGCACACGTTCTTCTGCAAGAATTGCCGTAAATCGAGCACGCCGCCGCCGGAGCCGCCGCCGCTGACGCACAAGTCGGGCATGACCCCGGCCGCGGCGGTGCCgctgccgcgccgcgccgcgcccgcgccgcagccgGTGCCCGTACCTGTACCTGTGCCGGTGCCGgtcgcgcgcccgcgccccgaCAAGCGCGTGCTGCTCAGGATGAAGGTGGCCGGCGGCGGGCCGGACGGCGAGCGCGTGTGGGCggtggcggcgccggcgccgacgcGCGCGCTGCTGCTGCGCCCGGCGCTGCCGCAGTCGCTGGCCGTGCTCAACGGCCGGCGCTTCATCGTCGTGCCGCGCGCGCTCGTGCAGCCCGAGCCTGAGAGTAAGCCAGTCCTGCGCGGGCGCGTGGCGAACGGCGCGGCGTCTCCTCCCGGCGCCCCGGGCGCCccgggcgccggcgccgcgggtGCCGGTGGCGCCGCCgcgtcgccgcgccgccgcgcccgcgccaaGCCCGACGACACCGACCACTTCACCGCCTTCTACAACAAGGCGCAGGAGCGGAAATATAACGTCGTCGTGCAGATATTCCAGTACCTGGGCATGCGCGAGCTGGCGCACTGCGCGCGCGTCTGCCGGCTGTGGCGCGAGCTGGCGGCCACGCCCGCGCTGTGGCGGCACGTGCGCATGAAGAACTCTCATGTGAGCGACTGGGGTGGGCTGGCGGCGGCGCTGCGGCGGCACGGCACGCGGCGGCTCGACCTGCGCAAAATGCTGCTGCCGCAGAACGACGCCGCCTTCTGGGACCAGTTCGCCGACCACGTGCACCAGCTCGCCGACCTCGAGAGGATAGAGATGTGCCGCTGCCCGGCGAGCGCGGTGGAGGCGGTGTGCCGCGGCGTGCGCGGGCTGCGCTCGCTGTCGGCGCTGGCCATCCGCTCGGCGCTGCTGGACCCCGCGCCGCTGGCCGCGCTGCCGCTGCTGCACGAGCTGCGCCTCAAGAGCATGGCCGGCCTGTCGCTCACGCGCGACCTGCAGCCGCTCGCCGCGCTCACCGGCCTCACGCATCTCTCCCTCACCTCCATCAAGGAGCTGGGTTGGTGCGCGTGCGACGTGGTGGGGCAGCTGCCGCAGCTGGAGTCCCTGGAGCTGGGCGAGTGCAGCTTCCGCGCAGAGTTCGCGCTCGTGCTGGCCAAGCTGGCGCGGCTGCGGCGCCTGCGCCTCGAGCGCGGCACCGCGCagtgcgccgcgcccgcgctgctgcGCGCGCTCGCGCAGCTGCCGCTGCTCGCCAGCCTCGAGCTCGTCAACTTCGACGTCAAGGTCGGATTTGACGACGCGCTGGCGGAGTGCAAGAACATACAGAGGCTGCTCATCATCCCGACCTACGTGTCGCAGTCCGCCACGACCAACCAACAGGTACTGAGCGGCGTTCTTCGGCTAAAGGACACGCTGACGCACCTGATGTGGGGCGTGACGATCGAACTGCTGCGGGTCACCGAGCTGTTCATCGACCAGTGCGAGCAgggcgccgagcgccgccgcgacGTCGGCGAGTGCATCCCGGTGCTCAAGCCCGTGCCCGGCTGCCGCCTGCCCGCGCCCGAGCCGGAGCGCCAGCCCGCGCACCACCACACGCCGCCTCAGGTGGAGATCCTCCCGCTGCCGACGCTGCAACGGCTGCTGTCTGCGCAGCTGCCCAACACCAAACTGAAGTTGCTGCGCATCCCGTTCCACGCCACCTGGCGCCAGTCGCTCGCCGACTTCCAGTag
Protein Sequence
MSEEMAVSDNPTGEESVVNGGEASAASAEDAAPAAPEPPSQPASEEPEDITPDAEPAPNEEPVADVEVKVEPIDEGDKRGTKRRASAAFSDVADEDFKGFAKMELDDSTLDYKRVLENLEAEVTEASKTVVPLQTVMGTPLGPVRASKRARQDTDGSRPSSALSSRSDGDGAISSTEVSSSSPAVRGRRATTEMSSPLLRVPLERGWKRELVFRAALDQHSRRNADIYYYTPQGKKLRSTREVSEHLSGTGLTIENFSFFKEPLGVDDPDKEIIRDAKMMRRVESPVAQAPPPTEGKRTPKPKQPKGASPEPQTPKSAPTKIKVKSIGSRLSNSAAPTPPAKPKKAPAADNNNSAAWKKNRTAPAPAAPPAPPPPLLSRPPAAPPAAGPVQRDEPARPQLVQPCSMTCGRGVPTLACAACLCLYHPACAGHTTAPHTFFCKNCRKSSTPPPEPPPLTHKSGMTPAAAVPLPRRAAPAPQPVPVPVPVPVPVARPRPDKRVLLRMKVAGGGPDGERVWAVAAPAPTRALLLRPALPQSLAVLNGRRFIVVPRALVQPEPESKPVLRGRVANGAASPPGAPGAPGAGAAGAGGAAASPRRRARAKPDDTDHFTAFYNKAQERKYNVVVQIFQYLGMRELAHCARVCRLWRELAATPALWRHVRMKNSHVSDWGGLAAALRRHGTRRLDLRKMLLPQNDAAFWDQFADHVHQLADLERIEMCRCPASAVEAVCRGVRGLRSLSALAIRSALLDPAPLAALPLLHELRLKSMAGLSLTRDLQPLAALTGLTHLSLTSIKELGWCACDVVGQLPQLESLELGECSFRAEFALVLAKLARLRRLRLERGTAQCAAPALLRALAQLPLLASLELVNFDVKVGFDDALAECKNIQRLLIIPTYVSQSATTNQQVLSGVLRLKDTLTHLMWGVTIELLRVTELFIDQCEQGAERRRDVGECIPVLKPVPGCRLPAPEPERQPAHHHTPPQVEILPLPTLQRLLSAQLPNTKLKLLRIPFHATWRQSLADFQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01134808;
90% Identity
-
80% Identity
-