Dros006059.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Diplolepis rosae
Gene Symbol
LZTR1
Assembly
GCA_030998225.1
Location
JAPYXD010000179.1:828902-839731[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 3.9e-13 3.5e-10 41.9 0.0 2 108 351 486 350 488 0.87
2 4 1.9 1.6e+03 1.1 0.1 76 108 486 518 481 520 0.85
3 4 1.6e-19 1.4e-16 62.5 0.0 9 96 580 667 573 682 0.84
4 4 1.8 1.6e+03 1.1 0.0 76 99 681 704 671 711 0.82

Sequence Information

Coding Sequence
ATGGATAGTGTAGCCACAGCTGAGTGCCTGACGTTGGATTTTGGTCCTTTCGAAACTGTTCATCGCTGGCAGCGAATGCCGGAATGTGCAGAATTCGTTGGAGCTAGACGTAGTAAACACACCGTCGTTGCTTATAAAGATGCACTATATGTTTTTGGTGGAGATGATGGTAAACGAATGTTAAATGATTTGCTTCGTTTTGACGTAAAGGAGAAGTCATGGGGTAGAGCTCTTGCAAATGGGGTACCACCTGCGCCACGGTACCATCATTCTGCAGTCGTACATGATTCATCTATGTTCGTTTTTGGTGGATATACTGGAGACATACACTCAAATTCAAATCTTACAAATAAAAATGACTTATttgagtacaaatttcaaacgGGACAATGGACAGAATGGAAATTCATCGGAAAaactccAGTTGCAAGATCTGCTCATGGCGCAGCGGTTTACGACAATAAATTGTGGATTTTTGCTGGATACGATGGTAACGCTCGCCTTAACGACATGTGGACAATTTCTTTATCGCCTGGAGATCTTAGAGTTTGGGAGGAAGTGGTACAATCTGGAGATTGCCCACCAACTTGCTGCAATTTTCCAGTGGCTGTTGCTCGTGAATCCATGTTTGTATTTAGTGGCCAGAGTGGGGCAAAAATCACCAACAGTCTTTTCCAGTTTCATTTTCGGGATAAGAGATGGACTAGAATTTCGACAGAGCATATTTTAAGAGGTGCGCCACCTCCACCGGCCCGTCGTTATGGTCACACAATGGTCAGCTTCGATCGTCATCTTTACGTGTTTGCGGGAACTGCTGATTCTACCTTACCAAACGATCTTCATTGCTACGATCTTGATACGCAGACATGGAATATTATTTTTCCGTCTACTGATAGTCAGATCCCATCAGGTCGGCTATTTCATGCAGCAGCTGTGATTGGAGAGGCGATGTTTATTTTCGGTGGAACTGTCGACAACAACGTTCGATCTGGGGAAACGTATCGCTTCCAATTTTCCTCTTACCCAAAGTGCACCTTACACGACGATTTTGGAAGACTTTTAAACAATCGTCTTTTCTGTGACGTTGAGTTCATTGTTGGAGAAAGTGAGACCAAAATCCCAGGGCATATCGCAATCGTGGCAGCGAGATCACAGTTTCTTCGAGCTCGAATTAAACAAGCTCGTGAACGACTAGATAAACACTTAGAAGATATAATTGGTTCCGTCGAAACACCAATTAAAAATTTCCCTCTGTTAGAGGTAAAACTAATTGATGCAGTACCTGAGGCTTTCGAGATGGTGTTGAATTACATCTACACAGATCGTATCGATCCTACTAAGCGAATTGAAGATCCTTTAAGCAACCGAATAGTTCTTCTCATGATGGATGTTTATAGACTCGCCGTACAATTCAATATGAAACGTCTGGAACAGCTCTGCGTTCATTATCTTGAAGCCACTATAAGTCATGCTAATGTCTTAGAAGCTTTGCACAATGCAGCTCACCTAAAACTCTactttataaaagaattttgtttgagTTTTGTTGTAAAGGAAAGTAACTATAATCAGATCGTTATGAGTCAGGAGTTCGAGACTTTAGATCAACCTTTGATGGTTGAGATTATCAGAAGGCGGCAAATGCCACAGAcgaagaatttttctaaacatTATGAACTAGGAACAGGAACGACTTTAGAACAAGACCTGGAGGCATTTTTAAAGACTGTTGGACGTGAATTTTGTGACATTACACTGATTCTGGATGGAGTACCGATTCCAGCACATAAAGCAGTACTTGCAGCGAGATGTAGCTATTTTGAGGCTATGTTTCGATCATTTATGCCTGAAAACAATACTGTCAATaTCCAGATCGGAGAAATGATACCATCTTCCGAATCTTTTGATTCTCTCTTAAGGTATATTTACTATGCCGATGTCTCTATGCCACCAGAAGACTCTCTATATCTTTTCACTGCACCTATTTTCTACGGATTCACAAACAATCGACTGCAGGCGTTTTGTAAACAGAACTTGGAGATGAATGTCACGTTTGAAAATGTAATACAAATTTTGGAGGCAGCAGACAGAATGCAGGCCGTTGACATGAAAAAATATGCTTTGAATCTCATTGTGCTTAATTTTAGTAAAGTTTCGCGTCTTCCGAGATTAAAACAATTGAATCGGGATCTCTTGCTGGATATTATAGAGGCTCTCGCTGATGAACGGAGCGAGGCGCGAACTTGTCAGGATATCTGGTCCAACGACTGA
Protein Sequence
MDSVATAECLTLDFGPFETVHRWQRMPECAEFVGARRSKHTVVAYKDALYVFGGDDGKRMLNDLLRFDVKEKSWGRALANGVPPAPRYHHSAVVHDSSMFVFGGYTGDIHSNSNLTNKNDLFEYKFQTGQWTEWKFIGKTPVARSAHGAAVYDNKLWIFAGYDGNARLNDMWTISLSPGDLRVWEEVVQSGDCPPTCCNFPVAVARESMFVFSGQSGAKITNSLFQFHFRDKRWTRISTEHILRGAPPPPARRYGHTMVSFDRHLYVFAGTADSTLPNDLHCYDLDTQTWNIIFPSTDSQIPSGRLFHAAAVIGEAMFIFGGTVDNNVRSGETYRFQFSSYPKCTLHDDFGRLLNNRLFCDVEFIVGESETKIPGHIAIVAARSQFLRARIKQARERLDKHLEDIIGSVETPIKNFPLLEVKLIDAVPEAFEMVLNYIYTDRIDPTKRIEDPLSNRIVLLMMDVYRLAVQFNMKRLEQLCVHYLEATISHANVLEALHNAAHLKLYFIKEFCLSFVVKESNYNQIVMSQEFETLDQPLMVEIIRRRQMPQTKNFSKHYELGTGTTLEQDLEAFLKTVGREFCDITLILDGVPIPAHKAVLAARCSYFEAMFRSFMPENNTVNIQIGEMIPSSESFDSLLRYIYYADVSMPPEDSLYLFTAPIFYGFTNNRLQAFCKQNLEMNVTFENVIQILEAADRMQAVDMKKYALNLIVLNFSKVSRLPRLKQLNRDLLLDIIEALADERSEARTCQDIWSND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00087267;
90% Identity
iTF_01392110;
80% Identity
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