Basic Information

Insect: Dicycla oo
Gene Symbol: IKZF1_1
Assembly: GCA_948252095.1
Location: OX411712.1:11578241-11589024[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 3 3.7e+02 3.0 0.9 1 23 54 77 54 77 0.94

2 20 0.083 10 7.9 4.1 1 23 84 107 84 107 0.97

3 20 4.8 5.9e+02 2.3 4.0 1 23 193 215 193 215 0.96

4 20 0.0017 0.2 13.2 1.0 2 23 221 242 220 242 0.97

5 20 1.5 1.8e+02 3.9 1.6 1 23 248 270 248 271 0.94

6 20 0.2 24 6.7 3.4 2 22 504 524 503 524 0.95

7 20 0.083 10 7.9 2.6 1 23 621 643 621 643 0.95

8 20 3 3.7e+02 3.0 0.3 2 23 780 801 779 801 0.95

9 20 0.0011 0.13 13.8 0.5 2 23 881 902 880 902 0.96

10 20 0.13 15 7.3 0.3 1 23 910 932 910 932 0.97

11 20 4.8 5.9e+02 2.3 2.6 1 23 968 990 968 990 0.93

12 20 0.00023 0.028 15.9 4.0 1 23 998 1020 998 1020 0.99

13 20 0.042 5.1 8.8 1.8 1 23 1099 1121 1099 1121 0.99

14 20 0.12 15 7.4 0.2 2 19 1206 1223 1205 1227 0.93

15 20 0.0021 0.26 12.9 1.0 1 23 1292 1314 1292 1314 0.96

16 20 0.0065 0.79 11.4 0.4 1 23 1320 1342 1320 1342 0.96

17 20 0.0065 0.79 11.4 2.6 1 23 1432 1454 1432 1454 0.97

18 20 0.00016 0.02 16.4 1.4 1 23 1460 1482 1460 1482 0.99

19 20 0.32 39 6.0 2.9 1 23 1574 1596 1574 1596 0.96

20 20 0.0091 1.1 10.9 5.8 1 23 1607 1629 1607 1629 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	3	3.7e+02	3.0	0.9	1	23	54	77	54	77	0.94
2	20	0.083	10	7.9	4.1	1	23	84	107	84	107	0.97
3	20	4.8	5.9e+02	2.3	4.0	1	23	193	215	193	215	0.96
4	20	0.0017	0.2	13.2	1.0	2	23	221	242	220	242	0.97
5	20	1.5	1.8e+02	3.9	1.6	1	23	248	270	248	271	0.94
6	20	0.2	24	6.7	3.4	2	22	504	524	503	524	0.95
7	20	0.083	10	7.9	2.6	1	23	621	643	621	643	0.95
8	20	3	3.7e+02	3.0	0.3	2	23	780	801	779	801	0.95
9	20	0.0011	0.13	13.8	0.5	2	23	881	902	880	902	0.96
10	20	0.13	15	7.3	0.3	1	23	910	932	910	932	0.97
11	20	4.8	5.9e+02	2.3	2.6	1	23	968	990	968	990	0.93
12	20	0.00023	0.028	15.9	4.0	1	23	998	1020	998	1020	0.99
13	20	0.042	5.1	8.8	1.8	1	23	1099	1121	1099	1121	0.99
14	20	0.12	15	7.4	0.2	2	19	1206	1223	1205	1227	0.93
15	20	0.0021	0.26	12.9	1.0	1	23	1292	1314	1292	1314	0.96
16	20	0.0065	0.79	11.4	0.4	1	23	1320	1342	1320	1342	0.96
17	20	0.0065	0.79	11.4	2.6	1	23	1432	1454	1432	1454	0.97
18	20	0.00016	0.02	16.4	1.4	1	23	1460	1482	1460	1482	0.99
19	20	0.32	39	6.0	2.9	1	23	1574	1596	1574	1596	0.96
20	20	0.0091	1.1	10.9	5.8	1	23	1607	1629	1607	1629	0.98

Sequence Information

Coding Sequence: ATGCTACAGCAGATGTCCTCGCCGCCGAGCGCACAAGTCGGCGAGGTCGCCACTATCGTGCGCCACCTTGAAGGCCGCGTCTGCGGCGACGTGTCTTCGGAGGCTTCCTCGGACGCCGCCGAAGATTTTGAATTACCACAGTGCAAGATAAGGAGGAATTATAATTGCACCAAGTGCACGTTCTATACGCAGAACCCGCGCGCTTATCTCGTCCACACGCGTGACGCTCACTTCGTTAGACTCAAGATTTACGATTGTCCACACTGTGTGTACGCTTCGAGGCATCATCAGAAACTTATAAGACACGTCAAAATGGTTCACGGAGGATCAAAGCCGACTTCTGCGGCTAGTAAAGTGGATGTAGAGCTATCACCTCCCTCTAACGATAACATGGAGCTAGCAGAGCGCATGGAAGACATGCTTGAGGAAGTCGAGGACTGCGAGGATATGATGATGGAAGTAGATGATGACTCCATGGACCAACCTGATGACATCGACGGCGACTGCGACAGAAGTGTTGAATACGCATCGCCCTCTTATCGGAGGGCACATCTGTCAAAAGCTAAGGGCAAATTCTTCTCATGCGATAAGTGCAACTATGTCACGCACATAAGAGCTAGATTCACAAAGCACGTCAAGTATCATTCGATGCCTATGATCAAGTGTACAATGTGTGATTTTCGAACGCCATACAAGTGGAATTTGGACCGTCACATGAAGAACCACGGTGGAAGTGGGAGTTTCTATTGTTCGATGTGCAACTTCACGGCGGACATCAAGCAGAGTCTGACGGTGCACGAAATGAATCATCATACACCGCCAGCGGGCCAATCGCTGTCGAGTCGCCGCCGCAACCGGGTGGGCGCCAGCGACACGGTTATCGCGGAGTTCGACGCAGCGAGCACGTTGCTCCCCAAGGAGGAAGAAGGGAGCGGCGACTCGCGGTCCTCACACTCGGTCTCGGACATGGGTCTCCAATATGCAGATAGAGAACTAGTCAGTTGCAAAAGTGATTCCAATGACGGTACAGCGTCTGACGCAATCACCAGAAAGGAGACTTCGCAAGATGGATACAACCAGCTTTCACCAACCCACAGCGCAGACGAGAAGCAACAAAAACAAAGCAGAAAGATTCCCCGACCAATACCACAACTCATACCGTTAAACTCTTCAACACCCAACCAAAAACAAACATGCTCTGGAGAACCGCCACAGAAAAAGTTTAAGGAATCTTTACCCATCGAAATTGATGAAGTGTCTGCTGAAAATACTTTTCTACCAGCAAATCCATTAATAAAAGAGACTGCAGCTCGAAAGAAAAATGAGTCGTTCTTCGACAGATTAAAAGAAAGACTGCTTACAGAAACAGGCGAAGAAGGTTCACTAATATGCAAGATCTGTGGATTTGAAAGTAAATGCCTATCAGAACATTCTGTCCACGAGAAAAATTGTTCCCCACAAACTAACCGGATCAATGCAAACACATCGCTTAAAAGTTTAAGTTCCACTCGATGTCAGAATTGCAGACACAGATGTAAATCTAGCGCTGACTTGTACATCCACATGCAAACTTGTGGCAAGAGCGAAAAGATCGACGATGAGAACACGATCAAAAATGAAAATAGTAATGATGAAGTCATTCCAATCCATGAAAAAGAGACTGAACCGCATCCAATGGAAAACGTCGTTTTCGTATGGAACAACATTAATCATGACCCTAACAAGTTTGATATACCTTTAGACATAAATATAAATGATGATTCCACTCTACCAGAAATACATCGAAGTTTTGACGCTGAGATTGTTGATGATAATGAAAGCATGAATTTGTCGCCGAGTCAAGCTATTGGAAGGAAGGTATTTAAATGTCCACATTGTCCATTTTTCTCCACAACAGCGTCCAGATTTCACGTTCATATCGTGGGCCACTTAAACAAGAAACCATTTGAGTGTTCCCTCTGCAAATATAAATCTAATTGGAGATGGGATATAACTAAACACATTAAATTGAAATCTGCGAGGGACCCTGAGCATAACGAAGCAAAAGTACTTATGACTGATGAAACAGGAAGAAGAAATTATAGCAAGTACAACAAATTCTTAGCAATGCCTGTTTTAAATGAAAATGGCGAAAATGAGTTTCACTACCTGGATCCTAATACTGCAGTCGATAGCACGATGGAAATGGATGAATCATTTAATGATGTATCAGACGTTACGAATGTACAATTTGAAATGCAACCGCTTAACTTACAGACTCAACACAGTGAAGATAATTACAACTATATTGATAACAGAGGTCTAAATGATATGAAGAAACCCAAGAAAACATTATGGAAATGTAAAAGATGTAATTACAAAGATCCCTCAAGAGAAGCTCTTTTAGAGCATGTTCGTGAACACTCCAGATCGGATGGCATCCATGATGAATTAAACAAACCGCCTATTAAGAAACCTGAAAATAATACTCCCGACCCAGCAGACCTTGCGTATCGTTGTGGCCACTGTAACCAATTGTCTAACTGGAAACATGTCATACAGCGCCATTGCCGATTAAAACACGATGGAGTGATCAAAGTGATAACTACAGTTAAACCAAAACCTGACCCACCAATGAACATCAATGAAATCAACATTGACACTTGCAACAAATGCCCGTACAGAACGAGTGACAAGAAACTACTCATTGCTCATTTACAACAGCATCAGCCCTCGCCGAATTCTATTTTCAAGTGCTACTTCTGCCCGTTCTTCGTAAAGGATGAGCCAGAATTAATCCAACATCTACTCCTGCATGGTATCACTGACCCAGAAGATTACATCGCAAAGGCAATGGGAACTAAATCCCCAGGAACAGAACCGCAAGCACCTGTTACTACGACATTAAACTCCACCAAGCGTCACAAATGCATAGAATGTCCATACGAAACAAATAGTAAGTCACAATTCATGTACCACGAACAATTTCATCGACTCCCGGCTGATACGCCATATAAATGTCCTGAATGCAACTACAGCGTATCTAAGAGACACCTGCTGCACCAGCATCTGCGAGTACACGGAATCAAAAGAATTGAAACTGAGGCTGAATTAGAAGCAGCACAAAACAAGCTATCTAAAATGGACTTCCATATTAATCTTGATGAAATACCATATGTTTGGGTTTCGGCCAAGAATGAGTTTCATAAAATGTTCAAGTGCAGATATTGTTCATACGTTAATGCCGTAAAAAGCAAAATACCAAATCATGAAAAAATTCATTGCATCGTATTCGAAAACAATGATACAACTGTCTACAAGTGTTTGGAATGCAAATTCACATGTGATAACGCCGGCAGGCTAGCCGAGCATTCCAGAACTCACGGGGAAATATATGGTCGCATTTATTGTCCCGTTGAACATGATGTACCCGATGATGAACAAATCACTAAGTTGAGAAAGGTTATAGAAATTGAAAAGTCAGCAAATCCAGAAAGTTTCTCTAGAGATGAAGGCGCTACGAACGAATTAAGAGAAATAAAATTATTATATTTTTGTCAAAAATGCCCAGCAAGATTTCTTGAAGACGGTGAACTCGACGTTCATGAAAAAAGTCACAATGTAACATTGCCGAATAAATGTAAAATTTGTGACTTTTCAGTCACCCAAGAAAATGAATTAGCGGCACATGACACCGTGCACACAGATGAATATCACACAAAAACTAAGATGCTTAAATTTGTTCACCACTCACATCCTTTGCACAAACAACCCGTGCTAGAGTTTGCTCTCTGTAAAAATACTTCAGAAATTACGTGGCGAGCCACTGGGCCAAGTAAGGCTGAACATATCGAAAGTCCTATGAAAAAAGATACAAAACACGGGCCAAAACAATATTACTGCAAACAATGTCCAGCTAAGTTCTTCAAAAGTTCCGCGCTTACCTATCACATGGGGTTACATGGAGGTGAGGGCGAGTATAAGTGCAAGAAGTGTAATTATGCCGTGAAAAACGTTGGAAATCTAGGCAAACATGAATTACTTCATGAAAATGAGAACAAGGCTACAACTTGTGACTATGAATCTGGTGAAGATTTGGATTATAAAAATATTCCTTTGTCGGGCACAGATTTGTTCCAGAGAAAGACTGAGGCTCAGAAGAGAGTATTAACTGATAAAGATAAGTTAGTTAAGCCGAACGATCATTTTCCGCCTGTCCTACAAGCCGATCCCCAATTCGGTTATTTAATGCATGGTAATCCTGAATTTATATATCCCACGTACCTGAAAAATGGACGTCAAAAAGAAAAGCGATACAAATGCCATAAGTGCCCCTCAGCTTTTGAGAAAAGGGAACAATATAAAATTCATTTGTCACTGCACGGCTCCAAGCAAAGATATAAATGTGAGTTATGTGATTATTCAGTAAAATATTACGCTAATTACGTTCAACATATGCGAAAACATCAGATGAATGATGAAGCTCAAGCTGAAAGAAAGAAAGATAATAATGATTTTACAGAATCTGAACATCAAGAAGACGTTAAGCAAGAGGACAGCAGTGATAACATTAAACTTGCAATAAAAACTATGCCAAAAGGAGCTGCTAAGAGCGACTTCCAACAATTCTCAATTAGCGACCAGCAAACGCTCAGACTGCTGCAGAGGAGACGGTCAATGAATAATTCTGGAAAGGACCACATCACTTCTGAAACTTCGCCGATAAAAGAGCGCAAAATGCACATGTGTCTGTTATGTCCCTATACTAACCAACGTCAAGATTCTTTAACCAATCATTACAGAAGGCACGGTGACACCGATGTTCTGAACGGCGGAAGTCATAAATGTACCCATTGCGACCTAGTGGTTGTTCAGTCGCATTTCCTTCGGGAACATCTGAAGACACACTTCAACTACCACAAAACTCTTATTCCCGAATGTTTTGTGGCTAACGAAGCTGTCAGTTTTACCATAACCAAGTTGGATGAAGACAGTGAATCAGTTGATCTCAAATTAGACATGCAGAACAAGAGTTTTGCATGTAATGATGACAAAATATTTGTGAAAATTAAAACTGGAGAGTTATTGGTGGAATAA
Protein Sequence: MLQQMSSPPSAQVGEVATIVRHLEGRVCGDVSSEASSDAAEDFELPQCKIRRNYNCTKCTFYTQNPRAYLVHTRDAHFVRLKIYDCPHCVYASRHHQKLIRHVKMVHGGSKPTSAASKVDVELSPPSNDNMELAERMEDMLEEVEDCEDMMMEVDDDSMDQPDDIDGDCDRSVEYASPSYRRAHLSKAKGKFFSCDKCNYVTHIRARFTKHVKYHSMPMIKCTMCDFRTPYKWNLDRHMKNHGGSGSFYCSMCNFTADIKQSLTVHEMNHHTPPAGQSLSSRRRNRVGASDTVIAEFDAASTLLPKEEEGSGDSRSSHSVSDMGLQYADRELVSCKSDSNDGTASDAITRKETSQDGYNQLSPTHSADEKQQKQSRKIPRPIPQLIPLNSSTPNQKQTCSGEPPQKKFKESLPIEIDEVSAENTFLPANPLIKETAARKKNESFFDRLKERLLTETGEEGSLICKICGFESKCLSEHSVHEKNCSPQTNRINANTSLKSLSSTRCQNCRHRCKSSADLYIHMQTCGKSEKIDDENTIKNENSNDEVIPIHEKETEPHPMENVVFVWNNINHDPNKFDIPLDININDDSTLPEIHRSFDAEIVDDNESMNLSPSQAIGRKVFKCPHCPFFSTTASRFHVHIVGHLNKKPFECSLCKYKSNWRWDITKHIKLKSARDPEHNEAKVLMTDETGRRNYSKYNKFLAMPVLNENGENEFHYLDPNTAVDSTMEMDESFNDVSDVTNVQFEMQPLNLQTQHSEDNYNYIDNRGLNDMKKPKKTLWKCKRCNYKDPSREALLEHVREHSRSDGIHDELNKPPIKKPENNTPDPADLAYRCGHCNQLSNWKHVIQRHCRLKHDGVIKVITTVKPKPDPPMNINEINIDTCNKCPYRTSDKKLLIAHLQQHQPSPNSIFKCYFCPFFVKDEPELIQHLLLHGITDPEDYIAKAMGTKSPGTEPQAPVTTTLNSTKRHKCIECPYETNSKSQFMYHEQFHRLPADTPYKCPECNYSVSKRHLLHQHLRVHGIKRIETEAELEAAQNKLSKMDFHINLDEIPYVWVSAKNEFHKMFKCRYCSYVNAVKSKIPNHEKIHCIVFENNDTTVYKCLECKFTCDNAGRLAEHSRTHGEIYGRIYCPVEHDVPDDEQITKLRKVIEIEKSANPESFSRDEGATNELREIKLLYFCQKCPARFLEDGELDVHEKSHNVTLPNKCKICDFSVTQENELAAHDTVHTDEYHTKTKMLKFVHHSHPLHKQPVLEFALCKNTSEITWRATGPSKAEHIESPMKKDTKHGPKQYYCKQCPAKFFKSSALTYHMGLHGGEGEYKCKKCNYAVKNVGNLGKHELLHENENKATTCDYESGEDLDYKNIPLSGTDLFQRKTEAQKRVLTDKDKLVKPNDHFPPVLQADPQFGYLMHGNPEFIYPTYLKNGRQKEKRYKCHKCPSAFEKREQYKIHLSLHGSKQRYKCELCDYSVKYYANYVQHMRKHQMNDEAQAERKKDNNDFTESEHQEDVKQEDSSDNIKLAIKTMPKGAAKSDFQQFSISDQQTLRLLQRRRSMNNSGKDHITSETSPIKERKMHMCLLCPYTNQRQDSLTNHYRRHGDTDVLNGGSHKCTHCDLVVVQSHFLREHLKTHFNYHKTLIPECFVANEAVSFTITKLDEDSESVDLKLDMQNKSFACNDDKIFVKIKTGELLVE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01231174;
90% Identity: iTF_00726922;
80% Identity: -