Doo005936.1
Basic Information
- Insect
- Dicycla oo
- Gene Symbol
- egg
- Assembly
- GCA_948252095.1
- Location
- OX411738.1:10670322-10742636[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 2.9 1.9e+04 -3.6 0.1 28 38 1936 1965 1925 1966 0.60 2 2 4.7e-13 3e-09 37.4 0.0 4 73 1997 2059 1994 2063 0.88
Sequence Information
- Coding Sequence
- ATGAGTGATTTAGAAGAAAAAAGCAGTTATGATGAGGAAAGTACGCAAATAAATCCAGACGAAGGTAGCAAAAGCCCTAAAATAATAGCTGAGGTGAGGGTATCTTTAGATTCCTATAAAAATACAGAAAATTGTGGCGGAATACCTGAAAATATGCCTCTGGCAAAAGCTAAAGAAGGGTCTGGAGATGATAAAAGACTCATGTTAGAAGATAACTCAAAACTTCATAAAATAGAAGTAGAGTTGGCAGATATGTCAAAAGAATTCATAAATACTGATGCAGGAAAAGGTACTGGTGACTATACAGCCAACGCAAAGGTCAGTGATATAGATGATATAAATATTGAGGATGTAAGCACTGAAATTGATGAAAAAATATCGACTACCTATGTTACTGCTGAGAAAGATGAAAGCAATAACACTTTTCTTGACAAATGTGATAAAATTGAATCTGAGAAGGCTGATGATCTTGACGAAATTGAAGATGAAGATATGGAACTAACTCTAAGATGGGACGATGATGAATCCAGCAATCAAGTTATGGGTGAAGTTATTGCAAATGCAGATGTTAAGAATGGTGATAATCTATCCAAAGACCAACTTTTGGAAGAACCTTCAGATGTTTTAACTAAAGATATGACTGAAATGCCTTCTGATGGGAATCCCAAAGTTTCGGAAGCCAATCTTGATAGTGATGTGTTAAAAGTAAACAGTGAAGAAAATAGTCTTACAAGAGTCAATGATTCCAATGAAATAGAAACTACTAAAGAATCTGAAATTAGTCCAAAACTGGACATTCCTACAGATAAGGCTGAAGATGAAAAAAGCTTGGACGATGAGGTTTTAGAGGAAAATGACTTAAGTACTGAAGCAATAAATAGCCCAGAAATGGTGTTTTCGGCAGAAGAAAGTATGGATCAAGGTGACATCAATGTTTTTACTGAAGCAATAAATAGCCCAGAAATGGACTTTTCCGCGGAAGAAAGTATAGATCGAGATGACATCGATGTTTTAGAAGAGAAATTACTGAAAGAATCTGAAATTGTCACTGAAACAGCGGTAATAGCTCAGCCAAAGGACATTATTGAAGAGAAAAGTATGGATGAACCAATAAAAGAGACAGAATCTGCAAAAAACAATCTTCTAAAGGAGGTTACTACTAATGAACAGACAAAAAAAGATCCAGTTATTGAAGAAGATCAACTTTTAGCTGAATCTGAAAGTAATACTAAAATAGACTCTTCAAAATTGAAGTTGAAATCTTTAACAGATGTCATCTCAAACAAAGATAATTATGATATTATGTCTGAAGAAAATCTTTTAGAAGAACCTGATTCTAAGGATGAAACTTCTTTGATTATTTCTGAGAAAGACATTGAACATCCTAAAATTGTTCCTGCAAAACAAGTCCCTATGAATAAAGAAGATAATGATGATGTTCTGCTAGAAGAAAAACTACTAGAAGAAACGGAAACAGCTGGAGTGATTCCCGAAAGTGATATAACAATGGATGTTGATGATGAGGAAGAAGGACAGTTACTGAAAGATGATGAATTTCAAGAAGATAGCTCTACTCTTATGGATGTTGACAATAAGGATGCATCTATTGGAGATCAAACTAATATAGCAGATAAGATTATAGATCAAACAATGAATGAAGTAGCAAAAAAATATATAGCTCTCCCAATAGATGACCAAACTTATACTAAAAAGTCAGTTAAATATACTACAAAAACAGTAGGTATTATTAAAGATACACCAAACGAAGACGAAGCTAAAATCGATGACAAAATTGTAGATCAAGCTATATTTGAAAAAGAGACTATTGATCAATTCATTCTTGAATGTAATACAAATGAACAGCGTATTAAGAGTCCTGTGCAAACAGATGCACTCACTGTTTCTAAAACTCCTAACATTCTTGTTGAAGATCTAAAGAAACCTATCCCAGAGAAAACTACTCTTGAAAAAGAAACTAAACATAAAACTGACCCAGATAAACCTAATGAAAATATAAACATTCAATTAATTTTTGAATGTAATACAAATGAACAGCCTATTAAGAGTCCTGTGCAAACAGATGCACTCACTGTTTCTAATACTCCTAACATTCTTGTTGAAGATCTAAAGAAACCTATCCCAGAGAAAACTACTCTTGAAAAAGAAACTAAAAATAAAACTGACCCAGATAAACTTAGTGAAAATATATACAAAGATACAGATTTAGATGGACCTGAAAGAAGTAAAGGAACTATCAATCCAGACACTAGCTTAGTTAAAAACAAAGAGGATGATGAAATTTCTCCTAACAACTCGTCAATATTTCTAGAAGATTCGTGTCCTATCATAACTGACCATGGTTTACATAAACCAGATGTAATGTTAGAAATACCTACACAAGAGTTAATTGACATGGATGAAACAGATTTGTCTATGAATTTAGACCATTCGGAAGGGATTGACGGTCTTGATGATTTTGACAAAAATGTTGAAGACGACATAATACATGAGAAAACAATTGATGAAACTGTCATTGATGATGTCATAGTAAGTGATAAAGTTGTCACTGTTGATGCTACTGTCAGTGAGAAATCAGTAGCTAAAACTAAAGCTGACAATGACACAATAAAAGAGAAACCATTTGATGAAAAAGCCTTAGTTACTGAAATAACAGCTGTTGATAAAATCATTGCTGATGACGACATAATGAAAGAGAAATCAGTAGATCAAGAAGCCATAGTGACTGAATCTACAGTAAGTGAAGTAAAAACAGATAATAATACTGTGCAAATTGACAAGAAAATTGAAGATACTGTTGTTCAGTCAACGGTTGAAGAAATCATGGAAATAATGTTTGCGGATAATGAGCCGGAAGTTGCTAAAGAAGTTATGGAGTGTATTGCATCCACAAGCCAAGTGCAAGTGCCCACTGAACTTCCATCGGCATCTATAACCCGTATGACTCCAGACACGTTGGATGAGGTTCCAGAGATAGATGATAGCCTGGGACTGTTGGCCGAGTCTGCGGGGCGGATGATGGAGGACGATGAGGAGCCTGATGATGATTTTGATGGTGATGATTTTGATAATGATGAAAGCAGCAACCAAATCTCAGCCGAACAGTCCGAGGATTCGAACTCAGCGGCCGTAGAGTCTGAACCAGTAAGAGACCAAGAAGACAAGGAGTTGGAGACTCCAGACCCTAAGGATGATGAGTTCCCGTTCATGGCGTGTGACAGTAACAGTGCCTCTCAGGATAAGGCGGAGAAGATGGATGTGGAAGAGTATGGGACTGTGGAATTACAGGCGGAAACAATGACGGAGATGAATGAAGAGGCAAAGTCGGCTGTTGATGCGTTGTTGAACGTTGATAACCCCCCCAATGAACAAGTTGAGGACCAACAAGAAACTGCAGATCAGATGGACGTAGAGACGGTGAAACTGTCAGATACATCTGATAATGAAATTGACGTTGAACCTACTAAGGTTCAACAGGCTGTGGCAGAACCAAGCAAAGAGAGTGAAGAACAAAACCAAAAGTTCTCACCATCTAAATCGCCAAACAAGAGCGTGCAATCACCAAGCAAGTTGAGCCAGTCGCCCTGTAAGCAATCCCCGAGCAAGATGATGAATTTGGCTATCACCACCCAAGAAGCTAGCTCGGTTGTTAACATTGTGGATTTGGAGGAAAGCAGCTCTTCTGAAGATGACATACAAGAAGTACAAAAGGAAATTGAACCAGAGACAACAGAGGACGCGAAATCTCCTTCCCCGGAATCAGATGTTACCAACGTTAACATACCAACGGGCATAGACATTATGTGTACTTCCGGCGGAAACACGTCAGAGATAACGACTAAAGACAACCTCTCCCAGGTTGTCATCAGTGGCGTGCCTAAGCCGCCGCCGCATAAGCCTGCCAGATTGAATACTAGTGAAGTTACGATCAAAACTGCTAGTAACACTGAACCATTGATTATACCTGAAACTAAGATTAATGAACAGACTCCAACACAGTCTAAACAAAAACTGAGTCTAGAAATATTTAGTCTAGATTCTGACGACGATGAAAGTGCAGCTAAAGAAAAATCATCTCCAACTTCCCCCGACAAAATGACAGCCTTGGTAGAACTAGAAAAAGCTCGAGAAACATCCAAATGTATCAACTATTTTTGCAAAAGTGACAACAAAGTGCCTTTCAAGCTGGCGGAGGCGTCAGTGGTCGCGTACTATGACGCGGGCAGGAAGCGTCGCTCCATGGTGTGCCAGCCATGCGCCGATGTTGTCGCTACTAGGAATAAGAATCTAATTCAAGGCATAAAAGACCTAACTCCGCTGTTAGACCTGGATATGGGCAAGTTATCACAAGACCTGGTGGAGATATCTGACTCGGAGTCTGAAGATGAAGAAATGAGTCCTGAAGAACCAAAGGAGAGTATCGGAGAGAAAGGAGCTAAATTCATAGAAGACAATCTAGCCAAGTATTTGAACGATACATGGAAGAAATACGAAATGGACGTGCGGCTCACAGAGACAAAGATCATGTTAGATGATGAGATTGAAAAACTCGAACAGGACAGCATACTAATAGACGCAATGCTAAACGAATGTCAGGTAGCGACAGACAAGCTTCGCTGTGAGTTATACGCGACGTTCGAGTGTCGACGACAACAACAACCCGCCCTAGTTATATATGACATCCCTGAGTCTAAAACTCGTCAAGCCAAGCGTCGTTTGTCGTCAACCAGTGAGACGCCTGCCAAACGTCCCGCCATACCTCTTGGATACGCACCTTTAGATGCCAGCGATAATAAGGAAAAAGCAGCAATCCCAGGACCAGAAACTAAACTAGACGATGACAAAGACATATCAGTAGTGAAACTCTCAGCGGAAGCCGCTCCAGCCGACCTGCCTCCCCCTGGCGAGATCTCCCGTCCCCCTCTGCGCCTGGGCATGCCGGTCTACGCCATGAAGAACGCCTTCGGACCCTGGCTTAAAGGCAAGGTGGTGGAGATACAGCCCAGGAATACGAGTGGGGGCAACCCATTCTCTCTGTGTCTTGTGAAATTCGACCATAAAGTCAAGACCAATGGGAAAGTATTGCAAGCAAGGTGCATCGCGTATTCTGAGCCCGCGGATGTTAGAATGACTATTGGTACTCGCCTAATAGCCCTGTTCAAGGATTCGAATAAGCGGGAATCTTACTACTCGGGAGTTGTCGCGGAAATACCCAATCCAGTCAATAATTATAGATACCTAGTATTCTTCGACGACGGTTATGCTCAGTATGTGCAACATCAATTTACTCGCCTGGTCTGCGAAAGTTCCCCCTTAGTATGGGAGGAAGTACATCCGTTCTCGCGAGAATTCGTCCGCGAGTACCTGATGGCATATCCAGAGAGACCCATGGTTAGACTGCATGAGGGGCAGCATCTGAAGACTGAGTGGAACGGAAAATGGTGGTCATCCCGTGTGACCCGCGTGGACGCATCTCTCGCGCAAGTGATGTTCGTGGGCGACGGGAGGCGCGAGTGGATATACCGCGGCTCCACGCGACTCGCTCCCTTGTACCTCGAGCTGCGCGCCGCTGAACGACACCGACCCAGACCCATGCCGAGGAGCAAGGCGCAGCCTAGGTTCAATATGCCGTACGTGGAGTACACTCGGTCGGATGAGCAGGAATCGAGCAAGCCAGTGGATGCGCAGGCGCCGCAACAACAGCAACAACAGCAGCAGCAGCAGCAGCAACAGATACAAAATGAGGAGATACGTCGCCAACGCTCCGTGGCCAAGAAGTCTACCTCAGCACCTCCTCAAGTGCTCCCGCCGTCACAACAGGTCATGCCCCCCACCCACATGGATCCGGTCACCAGCAGAGTTGTGTACTACACACCAAAGAACGCGGTGAAACCATTGAAGATGGTTCCACACAGGTGCGGTCCGAGATGCAAGAGAAGTGACGTATTGTCACTAAAAGAGTTGAGGACTTACAATCCATTGGCAAAACCACTGCTCAGTGGATGGGAAAGACAAATAGTACGCTTCAAAGGCCACAAAGAAGTGATGTACCGCGCACCCTGCGGCCGCCGCTTACGAAACATGCGCGAGTTACATAACTACTTACGTTCCATTGACAGCGACTTGCCTGTAGATCTGTTTGATTTCCACTACTCCACGCATTGTCTAGCGGAGTTCGTGCTCAACAAGTGCCTCGTGGGGAAAAAGGACCTCTCCCACGGCAAAGAGAACGTCCCAGTACCCTGCGTGAACTACTACGACGACTCCTTACCGGAGTTCTGTTCGTACAATACCGAACGCACTCCCACCGCAGGCGTGCCGCTCAACCTGGAGCCCGAGTTCCTGTGCGGCTGCGACTGTACCGACGACTGTCAGGATAAATCAAAATGCGCTTGTTGGAAAATGACTCTAGAAGGCGCTCGCACCATCGGGCTACGAGGACCTAATTTGGGCTATGTGTACAAACGATTGCCTGAACCGTTACCTTCTGGGATATACGAGTGCAATTCTAGGTGTAAATGCAAGCACACATGTCTAAACCGTGTAGCGCAACATCCACTACAATTAAAATTACAGGTATTTAAAACACCGAACCGTGGTTGGGGTATCCGGGCTCTGAACGACGTGCCAAAAGGCTCCTTCCTATGCGTGTACGCTGGTAACCTGCTCACAGATGCTACGGCTAACTTGGATGGTTTGAACGAGGGCGACGAATATTTAGCAGAATTAGATTACATAGAAGTTGTGGAACAGATGAAAGAGGGATATGAAGAGGACACTCCTGAGGCTGATAAGAAATTAGACAAGAAAGAAGCTAAGGATGGTGACGACAGCGACGAGGAGGAACAGTCATCCTCCGAGGATGAGGACAAGGCTGATAAGAATGACAAGCAAGACGATGACTTCAGACCGGGATACATTGGACTAGGCGTTACGCAGTTCAGCAAACGACTCCGTATACGCGAGAAAGCAAAGAAAGATAAAGAAAAAGCGGCGACTGATGAGAAAGAAAAGGAAAAAGATACGACTAAAGAATCGAATGCTGAAGACGATTGTATTACTATTAGTGATGATGAAGAAGTACGAGAACCTTCAAGATTCATGGCGCAAACGAACATGGGAGCTAGCGAATATATTTCTAAATACAAGTCTGTCCGCACGTTGTTCGGTAAGGACGAGGCATGCTATATCATGGACGCTAAGGTTCAAGGCAACATTGGCAGATATCTCAATCATTCCTGCTGCCCGAATGTGTTCGTACAAAACGTGTTCGTGGACACGCACGACCCTCGCTTCCCTTGGGTGGCGTTCTTCGCGCTATCACATATCAAAGCAGGTACAGAGCTCACTTGGAACTACAACTATGACGTGGGTTCCGTTCCCGGGAAGATACTTTACTGTTACTGTGGAGCTCCTAACTGTAGGGGACGGCTGTTGTAA
- Protein Sequence
- MSDLEEKSSYDEESTQINPDEGSKSPKIIAEVRVSLDSYKNTENCGGIPENMPLAKAKEGSGDDKRLMLEDNSKLHKIEVELADMSKEFINTDAGKGTGDYTANAKVSDIDDINIEDVSTEIDEKISTTYVTAEKDESNNTFLDKCDKIESEKADDLDEIEDEDMELTLRWDDDESSNQVMGEVIANADVKNGDNLSKDQLLEEPSDVLTKDMTEMPSDGNPKVSEANLDSDVLKVNSEENSLTRVNDSNEIETTKESEISPKLDIPTDKAEDEKSLDDEVLEENDLSTEAINSPEMVFSAEESMDQGDINVFTEAINSPEMDFSAEESIDRDDIDVLEEKLLKESEIVTETAVIAQPKDIIEEKSMDEPIKETESAKNNLLKEVTTNEQTKKDPVIEEDQLLAESESNTKIDSSKLKLKSLTDVISNKDNYDIMSEENLLEEPDSKDETSLIISEKDIEHPKIVPAKQVPMNKEDNDDVLLEEKLLEETETAGVIPESDITMDVDDEEEGQLLKDDEFQEDSSTLMDVDNKDASIGDQTNIADKIIDQTMNEVAKKYIALPIDDQTYTKKSVKYTTKTVGIIKDTPNEDEAKIDDKIVDQAIFEKETIDQFILECNTNEQRIKSPVQTDALTVSKTPNILVEDLKKPIPEKTTLEKETKHKTDPDKPNENINIQLIFECNTNEQPIKSPVQTDALTVSNTPNILVEDLKKPIPEKTTLEKETKNKTDPDKLSENIYKDTDLDGPERSKGTINPDTSLVKNKEDDEISPNNSSIFLEDSCPIITDHGLHKPDVMLEIPTQELIDMDETDLSMNLDHSEGIDGLDDFDKNVEDDIIHEKTIDETVIDDVIVSDKVVTVDATVSEKSVAKTKADNDTIKEKPFDEKALVTEITAVDKIIADDDIMKEKSVDQEAIVTESTVSEVKTDNNTVQIDKKIEDTVVQSTVEEIMEIMFADNEPEVAKEVMECIASTSQVQVPTELPSASITRMTPDTLDEVPEIDDSLGLLAESAGRMMEDDEEPDDDFDGDDFDNDESSNQISAEQSEDSNSAAVESEPVRDQEDKELETPDPKDDEFPFMACDSNSASQDKAEKMDVEEYGTVELQAETMTEMNEEAKSAVDALLNVDNPPNEQVEDQQETADQMDVETVKLSDTSDNEIDVEPTKVQQAVAEPSKESEEQNQKFSPSKSPNKSVQSPSKLSQSPCKQSPSKMMNLAITTQEASSVVNIVDLEESSSSEDDIQEVQKEIEPETTEDAKSPSPESDVTNVNIPTGIDIMCTSGGNTSEITTKDNLSQVVISGVPKPPPHKPARLNTSEVTIKTASNTEPLIIPETKINEQTPTQSKQKLSLEIFSLDSDDDESAAKEKSSPTSPDKMTALVELEKARETSKCINYFCKSDNKVPFKLAEASVVAYYDAGRKRRSMVCQPCADVVATRNKNLIQGIKDLTPLLDLDMGKLSQDLVEISDSESEDEEMSPEEPKESIGEKGAKFIEDNLAKYLNDTWKKYEMDVRLTETKIMLDDEIEKLEQDSILIDAMLNECQVATDKLRCELYATFECRRQQQPALVIYDIPESKTRQAKRRLSSTSETPAKRPAIPLGYAPLDASDNKEKAAIPGPETKLDDDKDISVVKLSAEAAPADLPPPGEISRPPLRLGMPVYAMKNAFGPWLKGKVVEIQPRNTSGGNPFSLCLVKFDHKVKTNGKVLQARCIAYSEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVQHQFTRLVCESSPLVWEEVHPFSREFVREYLMAYPERPMVRLHEGQHLKTEWNGKWWSSRVTRVDASLAQVMFVGDGRREWIYRGSTRLAPLYLELRAAERHRPRPMPRSKAQPRFNMPYVEYTRSDEQESSKPVDAQAPQQQQQQQQQQQQQIQNEEIRRQRSVAKKSTSAPPQVLPPSQQVMPPTHMDPVTSRVVYYTPKNAVKPLKMVPHRCGPRCKRSDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKEVMYRAPCGRRLRNMRELHNYLRSIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLEPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLRGPNLGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDTPEADKKLDKKEAKDGDDSDEEEQSSSEDEDKADKNDKQDDDFRPGYIGLGVTQFSKRLRIREKAKKDKEKAATDEKEKEKDTTKESNAEDDCITISDDEEVREPSRFMAQTNMGASEYISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKILYCYCGAPNCRGRLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00375248; iTF_00374144;
- 90% Identity
- -
- 80% Identity
- -