Cpyr001238.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cosmia pyralina
Gene Symbol
egg
Assembly
GCA_946251865.1
Location
CAMIUE010000035.1:199715-263421[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2.3 2.2e+04 -3.5 0.1 28 38 1844 1873 1833 1874 0.60
2 2 1.5e-12 1.5e-08 35.5 0.0 4 73 1905 1967 1902 1971 0.87

Sequence Information

Coding Sequence
ATGCCTCGGTCAGCAGATAAAGAACCATCTGGAGATGACAAAGGACGCATGTTACAAGATAACTCGGAACTTGATAAAATAGAAGCAGAGTTGACTGATATGCCAAAAGAATTCATAAATATTGATGCAGGCAAAGGTGACTATACAGCCAAAGCAAAGGTCAGTGGTATAGATGATAGAAAAATTGAGGATGTTAACACTGAAATTGATGCAAAACTATCGACAACCAATGTTACTGCTGAGAAAGATGGAAGCAATGACATTTTCCTCGacatatgtgataaaattgaaTCAGAGATGGCTGATGATCTTGACGAAACTGAAGATGAAGATATGGAACTAACTTTGAGATGGGATGATGATGACGCCAGCAATCAAGCTATGGGTGATGGTATTGGAAACACAGATGCTAAGAATGATGATATTATGTCCAAAAATCAACTTTTAGAAGAACATTTAGATGTTTTAACTAAAGATATGACTGAAATGCCTTCTGATGGGAACCCCAAAGTCTCTGTAGCCAATCTTGATAGTGAAGTGTTTAAAGTCAACAGTGAAGAAAATAGTCTTACAAGAGACAGTAATTCCAAAGAAATAGAAACTACTAAAGAATCTGAAATTAGTCCAAAACTGGACATTCCTACAGATATGGCTGATGATGAAAAAAGATTGGAAGATGAGCTTTTAGAGGAAAACGACATAAATACTGAAGCAATAAATAGCCCAGAAATGGACTTTTCTGCGGAAGAAAGTATGGATAGAGATGACATCAATGTTTTAGAAGAGAAATTACTGGAAGAACCTGAAATTGTCACTGAAGCAGCAGTAATAGCTCGAGCAACGGAGATTCTTGAAAAGAAAAGTATGGATGAACCAATAAAAGAGACAGAATCTGCAAAAAACAATCTTCTAAAGGTGGTTACTACTGATGAACAGACAAAAGAAGATCCAATTATTGGAGATCAACTTTTAGCTGAATCTGAAAGTAATACTTCAACATTAAAGTTGAAATCTTTAACAGATGTCTTCTTAAACAAAGATAATGATGATATTACGTCAGAAGAAAATCTTTTAAAAGAACCTGATTCTAAAGGTGAAAGTTCTTTGATTATTTCTGAGAAAGACATTGAATGTTCTAAAATTGTTCCTGAAAAACAAGTCCCTATGGATAAAGAAGATACTGATGATGTTCTGCTAGAAGAAAAACTATTAGAAGAAACGGAAACAGCTGAAGTAATTCCTAAAAGTGATATAACAATGGATGTTGATGATGAGGAAGAAGTTGAGTTACTGAAAGATGATGAATGTCAAGAAGATAGCTCTACTCCTATGGATGTTGACAATACTGATACATCTATTGGAGATCAAACTAATATAGAAGATAAGATTATAGATCAAACAATGAATCAATCTGAAGTAGCAAAAATAAATGTAGCTCTCCCAATAGATGACCAAACTTATATTGAAACAGTAGATGAAACAACTGATGAAATTAAAGTTTTGGATCAATCTGGTCATCAAAGCAAAATAATTGGGAATGTTATTGATCAGCCAATTAAAGATACATCAAAAATAGTAAGTTTTATTAAAGATACACCTAATGAAAATGAAGATAAAATCGATGAGAAAATTGTAGAGCAAGTTATATCTGAAAAAGAGACTATTGATAAATTAATTCAAGAATCTAATTCAAAAGAACAGCCAATTAAAATTCCTGTGCAAATAGATGCACTCACTATTTCTAATACTCCTAACATTCTTGTAAAAGATCTAAAGAAACCTATCCCAGAGAAAACTACTCttgaaaaagaaattaaaaataaaacagatccAGAAAAACCTagtgaaaatataaacaaagaTACAGATTTAGACGAAGCTGAAAAAAGTAAAGAAACTATCAATCCAGATACTAGCTTAGATAAAAACAAAGAGGCTGATGAAATTTCACCGAACAACTCGTCAATATTTCTAGAAGATTCATGTCctatcaaaactgatcatggttTACATAAACCAGATGTGATGTTAGAAATACCTACACAAGAATTAATTGACATGGATGATACAGATTTCTCTATGAATTTAGACCATTCTGAAGTGATTGACAGTCTTGATGATATTGACAAAAATGTTGATGACGACATAgtacatgataaaacaaatgaagaaacTGTCATTGATGATGTCATAGTAAGTGATAAAGTTGTCACTGATGACGCTACTGGCGGTGAGAAATCAGTAGCTAAAACTAAAGCTGATGACGACACAATAAAAGAGAGACCAGCAGATCAAAAAGCCTTAGTTACTGAAACAACAACTGTTGATAAAATCATTGCTGATGATGACATAGTGAAAGAGAAATCAGTGGATCAAGAAGCCATAGTAACTGAATCTACAGTAAGTGAAGTCCAAACAGAAAGTAATATTGTGGAAAGTGATAAGAAAGTTGAAGATACTGTTGTTCAATCTACAGTTGAAGAAAACATGGAAATAATGTTTGCGGATGACGAGCCAGAAGTTGCCAAAGAAGTTGCAGAGTGCATTGCATCCACAAGCCAACTGCAAATGCCCACCGAACATCCACCAACATCCATAACCCGTATGACTCCAGATACATTGGATGAGGTTCCAGAGATAGATGATAGTCTGGGACTGTTGGCTGAGTCTGCGGGTCGGATGATGGAAGATGATGAGGAGcctgatgatgattttgatggTGATGATTTTGATAATGATGAAAGCAGCAACCAAATATCAGCCGAACAGTCCGAGGACTCGAACTCAGCAGCCGTAGAGTCTGAACCAGTAAGAGAAGAAGACAAGGACTTGGATACTCCAGACCCTAAGGATGAAGAGTTCCCGTTCATGATGTGTGACAGTAGTACCTCTCAGGATAAGGCCGAGAAGATGGTTGTGGAAGAGTATGGGACTGTGGAATTACAAGCGGAAACAATAACTGAGATGAATGAAGAGGCAAAATCGGCAGTTGATGCTTTGTTGAACGCTGATAACCCCGCCAATGAACAAGCtgagAATCAACAAGAAACCACAGATCAGATGGACATAGAGACGGTGAAACTGTCAGATACGTCTGACAATGAAATTGACGTTGAACCAACTAAGGTTCAACAGGCAGTGCCTGAATCAAGCAAAGAGAGTGAAGaacaaaaacaaaagcacTCACCAAGTAAATCGCCAAACAGGAGCGATATGTCAAGCAAGCAATCACCAAGCAAGTTGAGCCAGTCATCACCCAGTAAGCAATCCCCGAGCAAGATGAAGAATTTGGCTATCTCCACTCAAGAAGCTAGCTCGGTTGTTAATATTGTGGATTTGGAGGAGAGCAGCTCTTCTGAAGATGAGATACAAGAAGTGCAAAAGCAAACGGAACCAGAGCCAACAGAAGACGAGCCAACCGAAGACGACAAAACGCCTTCCCCGCAGTCAGATGTTACCAACGTTAACATACCAACGGGCATAGACATAATGTGTACTTCCGGCGGAAATACGTCAGAGATAATGACTAAAGATAACCTCTCTCAGGTTGTTATAAGTGGCGTACCTAAGCCGCCGCCACATAAGCCTgcCAGATTGAATACCAGTGAAGTAACGATCAAAACTGCTAGTAACACCGAACCATTGATTATACCTGAAACTAAGATTAATGAACCGACTCAAACACAGTCTAAACCAAAACTGAGTCTAGAAATATTCAGTCTAGATTCTGACGACGACGAAAGTGCAGCTAAAGAAAAAACACCTCCGACTTCCCCAGACAAAATGACAGCCTTAGTAGAAGTAGAAAAAAGTCGAGAAACATCCAAATGTATCAACTATTTTTGCACGAGCGACAATAAAGTGCCTTACAAGCAGGCGGAGCCGACAGTGGTCGCGTACTACGATGCGGGCAGGAAGAGACGCTCCATGGTGTGCCAGCCATGCGCCGATGTGGTCGCTGCTAGGACTAAGAATCTAATTCAAGGAATAAAAGATCTAACTCCACTGTTAGACCTAGATATGGGCAAGTTATCACAAGACCTGGTGGAGATATCTGATTCGGAGTCTGAAGATGAAGATATGAGTCCTGAAGAACCCAAGGAGAGTATCGGAGAGAAGGGGGCAAAATTCATAGAAGACAATTTAGCTAAGTATTTGAACGACACGTGGAAAAAATACGACATGGACGTGCGGCTCACGGAGACACAGATCATGTTAGATGATGAGATTGAAAAACTTGAACagGATAGCAAAGAAATAGACGCAATGCTAAACGAGTGTCAGGTAGTGACAGACAAGCTTCGCTGTGAGTTATACGCGACGTTCGAGTGTCGACGACAACAACAACCCTCCTTAGTTATATGCGACACGCCGGACTCTAAATATATCGGACTAGAAGAACAAGCAAATCCTCCTGCCGCTGCCGAAACAATTGAGACTCGTCAAGCCAAGCGCCGTTTGTCGTCAACCAGTGAAACGCCTGCCAAACGTCCCGCCATACCTCTTGGATACGCACCTTTAGATGCCAGCGATGCTAAGgAAAAAGCGGCAATCCCAGGACCAGATACTAAACTAGATGATGACAAAGACATATCAGTAGTGAAGCTCTCAGCGGAAGCCGCCCCAGCCGATCTGCCCCCTCCCGGCGAGATCTCCCGCCCCCCCCTGCGCCTGGGCATGCCGGTCTACGCCATGAAGAACGCCTTCGGACCTTGGCTTAAAGGCAGAGTGGTGGAGATACAGCCCAAGAATACGAGTGGGgGCAACCCATTCTCTCTGTGTCTCGTGAAATTCGATCACAAAGTCAAGACCAATGGGAAAGTATTGCAAGCAAGGTGCATCGCGTATTCTGAGCCGGCAGATGTTAGAATGACTATTGGTACTCGCCTAATAGCTCTGTTCAAGGATTCGAATAAGCGGGAATCTTATTACTCGGGTGTGGTCGCTGAAATACCCAATCCAGTCAATAATTATAGATACCTAGTATTCTTCGACGACGGTTATGCTCAATACGTGCAACATCAGTTCACCCGCCTGGTCTGCGAAAGTTCTCCGTTAGTATGGGAGGAAGTACATCCATTCTCGCGGGAATTCGTCCGCGAGTACTTGATGGCGTATCCAGAGAGACCCATGGTCAGGCTCCATGAGGGGCAGCATCTGAAGACTGAGTGGAACGGGAAATGGTGGTCATCCCGTGTGACCCGCGTGGACGCATCACTCGCGCAAGTGATGTTCGTGGGCGACGGGCGGCGCGAGTGGATCTACCGTGGCTCCACGCGACTGGCGCCCTTGTACCTCGAGCTGCGCGCCGCCGAGAGACACCGACCAAGACCCATGCCTAGGAGCAAGGCGCAGCCTAGGATCAATATGCCGTACGTGGAGTATACTCGGTCGGATGAGCAGGAAGCGAGCAAGCCAGTGGATGCGCAGGCGccgcaacaacaacaacagcagcaaGAGCAGCAGCAGCAACAGATACAAAATGAGGAGATACGTCGCCAACGCTCCGTGGCCAAGAAGTCTACCTCAGCACCTCCTCAAGTGCTCCCGCCATCACAACAGACCATGCCCCCCACACACATGGATCCTGTCACCAGCAGAGTTGTGtactACACACCGAAGAACGCGGTGAAACCATTGAAGATGGTTCCACACAGGTGCGGTCCGAGATGCAAGAGAAGTGACGTATTGTCACTAAAGGAGTTGAGGACTTACAATCCATTGGCGAAACCACTTCTCAGCGGATGGGAAAGACAAATAGTTCGCTTCAAAGGCCACAAGGAAGTGATGTACCGCGCGCCCTGCGGCCGTCGCTTACGAAACATGCGAGAATTACATAATTACTTACGATGCATAGACAGCGACTTGCCTGTGGATCTGTTTGATTTCCACTACTCTACGCATTGTCTAGCGGAGTTCGTGCTCAACAAGTGTCTCGTGGGGAAAAAGGACCTCTCCCACGGCAAAGAGAACGTCCCAGTACCCTGCGTGAACTACTATGACGACTCCTTACCGGAGTTCTGTTCGTACAACACCGAACGCACTCCCACCGCTGGCGTGCCGCTCAACCTGGAGCCCGAGTTCCTGTGCGGCTGTGACTGTACCGACGACTGTCAGGATAAATCAAAATGCGCTTGTTGGAAAATGACGCTAGAGGGCGCTCGCACCATCGGGCTACGTGGACCTAACTTGGGCTATGTGTACAAACGATTGCCTGAACCGTTACCTTCTGGGATATACGAGTGCAATTCTAGGTGTAAATGCAAGCACACATGTCTTAACCGCGTAGCGCAGCATCCATTGCAATTGAAATTACAGGTATTTAAAACTCCGAACCGCGGTTGGGGTATCCGGGCTCTGAACGACGTGCCGAAAGGCTCCTTCCTATGCGTGTACGCTGGTAATCTGCTCACAGACGCCACGGCTAACTTGGATGGTTTGAATGAGGGCGACGAATATCTAGCAGAACTTGATTACATAGAAGTTGTGGAACAGATGAAAGAGGGATATGAAGAGGACATTCCTGAGGCTGATAAGAAATTAGACAAGAAAGACGCTAACGACGATGACGACAATGACGAGGATGAGCAGTCCTCCGAGGATGAGGATAAGGCTGATAAGAATGACAAGCAAGATGATGACTTCAGACCGGGGTACATTGGACTAGACGTTACGGAGTTTAGCAAACGCCTCCGTATACGCGAGAAAGTAAAGAAAGATAAAGAAAAATCGGCGACTGATGAGAAAGAAAAGGAGAAAGATACGACTAAAGAATCTAATGCTGAAGAGGATTGTATTACTATTAGTGATGATGAAGAAGTACGAGAACCATCAAGATTCATGGCGCAAACAAACATGGGAGCTAGCGAATATATATCTAAATACAAGTCAGTTCGCACGTTATTCGGTAAGGACGAGGCGTGCTATATCATGGACGCTAAGGTTCAAGGCAACATTGGCAGATATCTCAATCATTCCTGCTGCCCGAATGTGTTCGTACAAAACGTGTTCGTGGACACCCACGACCCTCGCTTCCCTTGGGTGGCGTTCTTCGCGTTATCACACATCAAAGCAGGCACCGAGCTCACTTGGAACTACAACTATGACGTGGGTTCCGTTCCAGGAAAGATACTTTACTGTTTCTGTGGATCTCCTAACTGTAGGGGACGGCtgttgtaa
Protein Sequence
MPRSADKEPSGDDKGRMLQDNSELDKIEAELTDMPKEFINIDAGKGDYTAKAKVSGIDDRKIEDVNTEIDAKLSTTNVTAEKDGSNDIFLDICDKIESEMADDLDETEDEDMELTLRWDDDDASNQAMGDGIGNTDAKNDDIMSKNQLLEEHLDVLTKDMTEMPSDGNPKVSVANLDSEVFKVNSEENSLTRDSNSKEIETTKESEISPKLDIPTDMADDEKRLEDELLEENDINTEAINSPEMDFSAEESMDRDDINVLEEKLLEEPEIVTEAAVIARATEILEKKSMDEPIKETESAKNNLLKVVTTDEQTKEDPIIGDQLLAESESNTSTLKLKSLTDVFLNKDNDDITSEENLLKEPDSKGESSLIISEKDIECSKIVPEKQVPMDKEDTDDVLLEEKLLEETETAEVIPKSDITMDVDDEEEVELLKDDECQEDSSTPMDVDNTDTSIGDQTNIEDKIIDQTMNQSEVAKINVALPIDDQTYIETVDETTDEIKVLDQSGHQSKIIGNVIDQPIKDTSKIVSFIKDTPNENEDKIDEKIVEQVISEKETIDKLIQESNSKEQPIKIPVQIDALTISNTPNILVKDLKKPIPEKTTLEKEIKNKTDPEKPSENINKDTDLDEAEKSKETINPDTSLDKNKEADEISPNNSSIFLEDSCPIKTDHGLHKPDVMLEIPTQELIDMDDTDFSMNLDHSEVIDSLDDIDKNVDDDIVHDKTNEETVIDDVIVSDKVVTDDATGGEKSVAKTKADDDTIKERPADQKALVTETTTVDKIIADDDIVKEKSVDQEAIVTESTVSEVQTESNIVESDKKVEDTVVQSTVEENMEIMFADDEPEVAKEVAECIASTSQLQMPTEHPPTSITRMTPDTLDEVPEIDDSLGLLAESAGRMMEDDEEPDDDFDGDDFDNDESSNQISAEQSEDSNSAAVESEPVREEDKDLDTPDPKDEEFPFMMCDSSTSQDKAEKMVVEEYGTVELQAETITEMNEEAKSAVDALLNADNPANEQAENQQETTDQMDIETVKLSDTSDNEIDVEPTKVQQAVPESSKESEEQKQKHSPSKSPNRSDMSSKQSPSKLSQSSPSKQSPSKMKNLAISTQEASSVVNIVDLEESSSSEDEIQEVQKQTEPEPTEDEPTEDDKTPSPQSDVTNVNIPTGIDIMCTSGGNTSEIMTKDNLSQVVISGVPKPPPHKPARLNTSEVTIKTASNTEPLIIPETKINEPTQTQSKPKLSLEIFSLDSDDDESAAKEKTPPTSPDKMTALVEVEKSRETSKCINYFCTSDNKVPYKQAEPTVVAYYDAGRKRRSMVCQPCADVVAARTKNLIQGIKDLTPLLDLDMGKLSQDLVEISDSESEDEDMSPEEPKESIGEKGAKFIEDNLAKYLNDTWKKYDMDVRLTETQIMLDDEIEKLEQDSKEIDAMLNECQVVTDKLRCELYATFECRRQQQPSLVICDTPDSKYIGLEEQANPPAAAETIETRQAKRRLSSTSETPAKRPAIPLGYAPLDASDAKEKAAIPGPDTKLDDDKDISVVKLSAEAAPADLPPPGEISRPPLRLGMPVYAMKNAFGPWLKGRVVEIQPKNTSGGNPFSLCLVKFDHKVKTNGKVLQARCIAYSEPADVRMTIGTRLIALFKDSNKRESYYSGVVAEIPNPVNNYRYLVFFDDGYAQYVQHQFTRLVCESSPLVWEEVHPFSREFVREYLMAYPERPMVRLHEGQHLKTEWNGKWWSSRVTRVDASLAQVMFVGDGRREWIYRGSTRLAPLYLELRAAERHRPRPMPRSKAQPRINMPYVEYTRSDEQEASKPVDAQAPQQQQQQQEQQQQQIQNEEIRRQRSVAKKSTSAPPQVLPPSQQTMPPTHMDPVTSRVVYYTPKNAVKPLKMVPHRCGPRCKRSDVLSLKELRTYNPLAKPLLSGWERQIVRFKGHKEVMYRAPCGRRLRNMRELHNYLRCIDSDLPVDLFDFHYSTHCLAEFVLNKCLVGKKDLSHGKENVPVPCVNYYDDSLPEFCSYNTERTPTAGVPLNLEPEFLCGCDCTDDCQDKSKCACWKMTLEGARTIGLRGPNLGYVYKRLPEPLPSGIYECNSRCKCKHTCLNRVAQHPLQLKLQVFKTPNRGWGIRALNDVPKGSFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEEDIPEADKKLDKKDANDDDDNDEDEQSSEDEDKADKNDKQDDDFRPGYIGLDVTEFSKRLRIREKVKKDKEKSATDEKEKEKDTTKESNAEEDCITISDDEEVREPSRFMAQTNMGASEYISKYKSVRTLFGKDEACYIMDAKVQGNIGRYLNHSCCPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKILYCFCGSPNCRGRLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00449132;
90% Identity
-
80% Identity
-