Dmen036621.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Diaphora mendica
Gene Symbol
Zfy1
Assembly
GCA_949125395.1
Location
OX421328.1:23383772-23389487[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 1.4 1.9e+02 4.2 0.9 3 23 247 267 245 267 0.94
2 16 0.21 29 6.8 0.2 6 23 279 296 279 297 0.95
3 16 0.16 21 7.2 0.1 3 23 309 330 307 330 0.91
4 16 7e-06 0.00094 20.9 0.8 2 23 353 374 353 374 0.97
5 16 1.4 1.8e+02 4.3 4.6 1 23 495 517 495 517 0.97
6 16 7.1e-05 0.0096 17.7 1.4 2 23 524 546 523 546 0.92
7 16 9.1e-08 1.2e-05 26.9 0.7 1 23 552 574 552 574 0.99
8 16 1.4e-06 0.00018 23.2 4.4 1 23 580 602 580 602 0.98
9 16 0.00019 0.026 16.4 0.4 1 23 608 630 608 630 0.98
10 16 0.28 38 6.4 4.1 1 23 636 658 636 658 0.91
11 16 4.8 6.5e+02 2.5 0.8 3 23 710 729 710 729 0.86
12 16 7.2e-06 0.00097 20.9 0.1 1 23 735 758 735 758 0.96
13 16 1.4e-05 0.0019 20.0 2.4 1 23 764 786 764 786 0.98
14 16 0.00064 0.086 14.8 0.0 1 23 792 814 792 814 0.98
15 16 0.0081 1.1 11.3 0.0 2 23 820 841 819 841 0.96
16 16 0.025 3.4 9.7 0.4 6 23 851 868 850 868 0.99

Sequence Information

Coding Sequence
atgaataacagCACTGAACAAGTGTATATATTAAATTCTGCACAAAGTCATCCACTAGGTTTAGCACAAAAGCAAGTACCGACAAACGGAACCACACCAGTCAATCTTGaaaATGTGGATAATTTCTCTAATGTGTGTCGGACATGTGCCACCATCACGCAACTTGTCATCCCCATATTTACCGGGGAGGGACTGGAGCATCACTTGGCTGAAAAAATACACAAACACTTGCCCATATCGGTTTCCGAGACTGACCTCTTACCTTTAGTGATGTGCTATCAATGTGTCAGCACACTGCTAGCTTGGCATGAGTTAGTGGAGTGCTGTTTGCAGGCTGATCGAGCCCTCAAAGCTAAGATCGGCGTAGATTCCACTACTGAAACTCCAAAGATAATCCAGGCACCTAGCATCACCACAGATGAGGATTCACAAAGCAAATCATATTACGGGATGGTGAGAAATGTTCTGGTGAAATACTTTCATCAATTGTCGTTGGAAGAAAGTTTGGACACAGAGATTGTCTGCCAGATGTGCGTAGAAAAACCTGCCTTGACAACTGTGGAAAGTCTAGCGGACCATTTGAAATACGATCATAGTTCACACAGTACCGACGAGGCAACAATAAAAACGTTTATCAAAAACTATGTAACGTTTGAGGAGGTGTTGGTTTTTGACGATTACGATAGATGCGAGACCGAAAGCACAGAAATAATTAAGAAACCTTTGCCTAATATATTTTGCCCTTATTGCGCAAGTGTCTTTTCGTCAGCAACGCGTTTAGTGTGTCATCTCAACAAGCATTTCCAAGTGACTATCGAAGATGGTGTCACCTGCTGCGGTATCGAGTATAACGATAAGAAAAACTTTGTGGTACATTTACAGGAACATCATGTCGAAAGAAAGAGAGACGGTCTGGAGAAAGTTTGCAAGTGTTGTGGTCTAGAAGTAGAAGATGCGAGTGAACTCCAAGCTCATATAAATGATGCACATCAAAAGAAAGACGTGTGTAAAACAAAGACACATCAGAGTCCCAAGAACCAGAAATATATCCCAGCGGTTTGTCCGGAATGTAATAAAACGTTTGCCAATAAATACAGCATGTTTCTACATATGAAAAACCATAACGCCGAAGTACGTACGTATTCCTGCGACAAGGACGACTCCCAGTTCCTGGATGCGTCAGAAACTTCAGACCGATCAGATGATAAACCGCTTTCTACATTATCTACTAAAAACCCTGAGGATTTGTACAGCAAGTTTTATAGAGCACTCGTTAACTTTAGAAATCATTTTGTCGGAGAACATGACAATCGAGAGTCTTATCCCGATTTCACCGACTCCTCCAGTGCATCAGAAGTCGAAGAAAATAGTATAGACGGTTACGACGACCTAACCAAGTGTAACATGAGAAAAGATATAATGGATAAGGAGACCAGACTGGAACTTAATCAGGTACAAACCAAGATTAATGGAAAAGTATTCTATACGTGTAGAATCTGCAGCAAGAACCTAAGCTCGTCGCACACATACATGTTCCATAAAAGAATACATACCGGCGAGAAGCCCTGCGTGTGTCACATATGTGGAAAACAATTCCGAGCTCCGAGCGGATTAATACGGCATCTGACGGAAACGCACGAACGTCTACGAAGATACACCTGCAGTGTCTGTCCTAAAAGCTTCGCCAATTCGCAGAATTTGAAGCAACATTTGAGGATCCACACCGGCGAGAGACCGTTCGTGTGCTCGCACTGCGGCAAAAGATTCACCCAGAGCGGTTCGCTGCACGTGCATTTAAAAACGCACAGTGAACTGTTTCCGTATTACTGCGCCGAGTGCGGGGCGAAATTCCGGCTTCGATCCGGTTTAGTGAGGCACAGGCTCAAGCACACGGGCGAACGACCGCACGTGTGCGCTCTCTGCGGGAAAGGATTTAGAGAACGACACGAATTAAACTGTCACAGTCTGTCTCACTCCGACGCGAAGCCCTTCTCTTGCACGGTCTGCGGGGCGGCGGCGCTCGCGGAGGTAAAGATCGAGAAATGCGACGGCGGCGGCGCCGTAGCGACGGAAAAGAATAGACCGACGGTGGCGACCGTCGCCTCCGACTCGCGGGGAACCGTGTGGTGCGAAAAGTGCAATAAGAGCGTATCGGTGGTGTCCCGGCGGAGACACGAGCGGCTGCACGACGGCGAGAAGCGGTACAGCTGCCACGCGTGCGGGCGCGCCTTCGCCGACAGCGGGAACCTCGCGCGGCACGTGCGCGCGCTGCACGCGCGGCTGCGGCCGTTCTCGTGCTCGACGTGCTCGAAGGCGTTCTCTCGGCGCGCGCACCTGGAGGACCACGAGCGCTCGCACGGGGAGCGGCGCGAGTTCGTGTGCGAGTGGTGCGGCGCGGCGTCCAAGTCGCGCGCGGCGCTGCGCATGCACGCGCGCACGCACGGGCCGCGCGCGCTGCGCTGCGTGGGCTGCGGCGCGCTGTTCGGGCGCGCGGCCGAGCTGCGCGCGCACCGCTCCGTGCACTCGGGCGAGCGCGCGCACGCCTGCGCCTGCGGCCGCGCCTTCCGCCTGCGCGCGCAGCGAGCGCGCCACCAGCGCACGCACCGCGCCGCCCCGCCCGACCCGACCGCGCCCTAG
Protein Sequence
MNNSTEQVYILNSAQSHPLGLAQKQVPTNGTTPVNLENVDNFSNVCRTCATITQLVIPIFTGEGLEHHLAEKIHKHLPISVSETDLLPLVMCYQCVSTLLAWHELVECCLQADRALKAKIGVDSTTETPKIIQAPSITTDEDSQSKSYYGMVRNVLVKYFHQLSLEESLDTEIVCQMCVEKPALTTVESLADHLKYDHSSHSTDEATIKTFIKNYVTFEEVLVFDDYDRCETESTEIIKKPLPNIFCPYCASVFSSATRLVCHLNKHFQVTIEDGVTCCGIEYNDKKNFVVHLQEHHVERKRDGLEKVCKCCGLEVEDASELQAHINDAHQKKDVCKTKTHQSPKNQKYIPAVCPECNKTFANKYSMFLHMKNHNAEVRTYSCDKDDSQFLDASETSDRSDDKPLSTLSTKNPEDLYSKFYRALVNFRNHFVGEHDNRESYPDFTDSSSASEVEENSIDGYDDLTKCNMRKDIMDKETRLELNQVQTKINGKVFYTCRICSKNLSSSHTYMFHKRIHTGEKPCVCHICGKQFRAPSGLIRHLTETHERLRRYTCSVCPKSFANSQNLKQHLRIHTGERPFVCSHCGKRFTQSGSLHVHLKTHSELFPYYCAECGAKFRLRSGLVRHRLKHTGERPHVCALCGKGFRERHELNCHSLSHSDAKPFSCTVCGAAALAEVKIEKCDGGGAVATEKNRPTVATVASDSRGTVWCEKCNKSVSVVSRRRHERLHDGEKRYSCHACGRAFADSGNLARHVRALHARLRPFSCSTCSKAFSRRAHLEDHERSHGERREFVCEWCGAASKSRAALRMHARTHGPRALRCVGCGALFGRAAELRAHRSVHSGERAHACACGRAFRLRAQRARHQRTHRAAPPDPTAP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00157417; iTF_00823276;
90% Identity
-
80% Identity
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