Dmen013727.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Diaphora mendica
Gene Symbol
-
Assembly
GCA_949125395.1
Location
OX421314.1:27043600-27054752[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 31 5.3e-05 0.0071 18.2 1.8 1 23 203 225 203 225 0.99
2 31 0.00084 0.11 14.4 0.3 2 19 257 274 256 277 0.94
3 31 1.3e-05 0.0017 20.1 0.1 2 23 315 337 314 337 0.96
4 31 0.00031 0.042 15.7 1.5 1 23 384 407 384 407 0.97
5 31 0.0049 0.66 12.0 1.0 1 23 425 447 425 447 0.95
6 31 6.7e-05 0.009 17.8 1.5 2 23 482 504 481 504 0.96
7 31 0.0035 0.47 12.4 6.3 2 23 543 565 543 565 0.97
8 31 0.0035 0.47 12.4 0.3 1 23 615 638 615 638 0.97
9 31 0.00054 0.073 15.0 0.1 1 23 692 714 692 714 0.97
10 31 0.0083 1.1 11.2 6.2 1 23 725 747 725 747 0.98
11 31 0.0088 1.2 11.2 0.7 2 23 759 780 758 780 0.96
12 31 0.0032 0.43 12.5 1.4 1 23 790 812 790 812 0.98
13 31 0.059 7.9 8.6 6.4 1 23 841 863 841 863 0.96
14 31 0.00097 0.13 14.2 4.1 1 23 874 896 874 896 0.98
15 31 1.4e-05 0.0018 20.0 0.7 1 23 904 926 904 926 0.98
16 31 0.00054 0.073 15.0 0.6 2 23 946 968 945 968 0.97
17 31 1 1.4e+02 4.7 0.2 1 23 986 1008 986 1008 0.90
18 31 0.11 15 7.7 3.7 1 23 1015 1037 1015 1037 0.97
19 31 0.0069 0.93 11.5 1.3 2 23 1048 1070 1047 1070 0.94
20 31 0.018 2.4 10.2 0.2 2 23 1093 1114 1092 1114 0.95
21 31 3.1 4.1e+02 3.2 3.5 2 23 1157 1179 1156 1179 0.95
22 31 0.01 1.4 11.0 0.2 2 23 1195 1216 1194 1216 0.95
23 31 2.8 3.7e+02 3.3 4.8 3 23 1224 1244 1222 1244 0.96
24 31 0.014 1.9 10.5 0.8 2 23 1255 1277 1254 1277 0.95
25 31 0.012 1.6 10.8 2.4 2 23 1294 1312 1294 1312 0.96
26 31 0.68 92 5.2 1.9 2 21 1316 1335 1316 1336 0.93
27 31 3.8 5.1e+02 2.9 2.7 2 23 1359 1380 1359 1380 0.93
28 31 1.7 2.4e+02 3.9 0.6 2 23 1387 1408 1386 1408 0.93
29 31 0.0002 0.026 16.4 0.7 2 23 1419 1441 1418 1441 0.96
30 31 5.5 7.5e+02 2.4 1.3 3 23 1458 1475 1457 1475 0.78
31 31 0.53 71 5.6 3.8 2 19 1479 1496 1478 1499 0.92

Sequence Information

Coding Sequence
ATGGCCCTCAAACTTGGAAAATGCAGGCTCTGCCTCAAACTTGGGGACTTTTATTCCATCTTTACGGTGGACAATTCATTACAGCTTGCAGAGATGGCAATGGAATGCGCTCGAATAAAAATATACGATGGAGACGGACTTCCAGACAAAGTTTGTTCAGAATGCATACAGAAGCTAAGTAGTGCTTATATATTCAAACAACAATGTGAGCGAGCAGACCAGGAGTTGCGGCGAAACTATGTTCCACCACCAGGGTTCAGTATCAGTCCACCGCCACCTACCAGACAGAGTAGTGACTCTGCCTTCTCAAATCACACTGACAGCTCTAATCTTACCAAACCGTCGTCTTCCTTTGAAGAAAAAATATCACCCGCAACCAGGACGCGGAAACGTAGTGTGGAGAGCGATGGAAACGTCTCAATGGGTGGTCAATCAAGCGATTTCAGACCAACCAGCTCCAAGCGGATTGAGGAActtaaaaattctcaaaaaaagAGGCCTCGTTTGCAATCTGAAAACACTTCACAGCCAGACTCCGATTATGAGGACAATAGCGGTTCATACGTACCTGAAACTGACTCGGATGAACCACTTATAAAGAACTCATTCAAGTGCAAGTCATGTCCAAAACAGTTTACAACCCTCAGAAGTTTGGCTAACCACACTAGAATTCACACTAAAAGCAATAGTAAGACACTTGACGTTGATTCCGTTGTAGACGAACCAAAGAACAGTATCGAGGATGCTGCAGATGTCGAAGATAAGCTGAGCTGTGATAAGTGTGGAAAAACTTTCAAACTGAAAATAATGCTAAAACGTCACTCTGATGTGTGCTTGAAAACACCTGTTAAATCGCCGCAGAAGGAACTCCTCATATCCTTGGCGCCTATAGACGCCAAACCAAATGCACCACAACCAACTGTACCAGCTGTAACAACGATACCATGTGAATATTGCGTTGCTACGTTTAAAACTCAGGATAACTTAGCGAAACATATGAAAGTGGTTCACGCGGCTGTTCTGAAGAGAGAAGCCGAAGCAAACAGAAAGGTGCCGGTTCCTTGCTTGTATTGCGACCTAATGTTCGATGACTATCACCAACATAATGCTCACTTTGTCGAATGTCCAAAGTTGGATGAGTCTAAGCCATACGTGTGCCCTGTATGTGACAAATTTACATCGAGGAGAACTTCATACTACCAACATCTTAGGAACATGCACTTTGAACCTCGCGTTTCGTACGTAGAGCCGGAAATTGAAATGCACGAATACCACGAGTGTCGCGTGTGTTCGAAGAAGTTAGCGTCTAAGGAACAACTGATCAAGCACTTGTCCGCTCATGTGTCCAATATCCAGGATGATGGCACACTTGACAATGACAGGGATGATGCAGATTCTATAAAATCAGTACAAAGCAACACGTATCCAGCTGGAGGTCCGTTGAAATGTGATGTTTGTGATAAGGAATTTAAGTACAAAAAAGCTTTGTTAACACATCAACAAAGATTTCACACAGATACCCCAGTGGAAGTAAAAGTCGAACCGCCCGATAAAGCTTCCACAAGCCTTTTGAGCGAGAAACAATATCGCTCAGACTCCGAATCTAGTCAAGAAGAAGAAGACAACACGTGCGATATTTGCGAGAAACATTTCTCCTACAAACGTCTCTTGCTCCACCACAAGAGGACAAAGCACAACATGAGCTCAGGCCACAAACGCGCCAAGATCTACCTCAAGGACTGCTCCGTCCGCTGCCTCATCTGCGATCTGCAAATGAAAGTCGGCGACATAAATGAGCACAATCAAACGCACATTGCTAAGAACATGAAACCTAGAAATCTGTACACGTGCGCGGAATGCGAAGCTACCTTTAAAGCGTGCAGTGCACTCGCAACTCATATAAAACTAGTACATAGATTAAAACAGCAAGTGGAAATCAATACGGTAAATCCGTCGGATTTTTGTGAAGTCGTTGTGACAAAGTCGGAACCGCTGGACTGGATCCAGAGTCACAACGACTTTGGTGAGGTTCCGATTGAGCAGGACGGCAAGCCACTGGTAGACCTGAGTGGCTTCACGTGTCCCATCTGTGGGAAGAAGATGCCAACACTGATATCACTGAAGAGACACGTGAATTGGCACACTAACGTTGGTAAGAACTTAGAAAAGAAATACGAGTGCTTTGTTTGCAAAGAGgCTTTTAGATTCCAATGTCACTACAAGCTACACATGCGCGAGCACTACACGGACACAGCTCTGGACCCGAGACACCTCACGTGCCCCATCTGCGGACGCAAGAGCAAACACCTACGAGCCGCTCAAGCGCACATGACCTACcacaaacaaacacgctttCAGAACAAAGACTATCAATGCTCCATTTGCGAAAGAGTATTTCAGCACAGAAAAGTGTACCTCTCCCACATGGCCATACATTACAAGAGAGGGGAAAGTGTTCAAAACACTATAGTAGGTTCCGTCTTACCTAACAATGTCGACAAGAACACTTTCGACGGAACCCACACCTGCATGCACTGTGGTAAAATCTGCGACTCTGAAAATTCTCTAAAACATCATCTTATTTGGCACACATCCAAGACTTTCTTATACGGGGCTCGGCACGAGTGCACGATTTGTAAAGTCAAATTTACTAATAAGAAACGACTCGAACTTCACACGAGAACGCACTATGAAGACGACAATGGGCCCTACAAATGCAACATATGTGGTAAAGGATACACAGACGAAGGCTACTTCAAAAAACATGTCAAGGGCCACAATTTCGATCACCAATCGCATAAAAAGAGGATAGAGAAGATCAGAAAGGATAAAGTGAAGTGTCCTATATGCTCCCGGTATTACAAGGACCTTATCAAACTTATCCGGCATCTCAGACGAACGCATCCCGAGAGTAAGATGATTAAGACAGACCCAGATGCGCCCCCACAACCTTACTTTTCATGTAAACTATGCGCTAAAGTGTTCTTAGATGAGAGAAGGCTTCAAGCGCATGAAGAAGCCCATTTGAGGAAGCCAGAGTTCTTTAAATGTAAGTTCTGCGGAAAGAAGACAATATCATTGAAGAATCACAGAGTCCACATTAAGGGTCATTTGACACAGAAGTATTTAGACAACCCTCTAAAATGTCCGCACTGTGAAGAGACGTTCGGGCGAGGCTACGACCTCCACTACCACGTGCGCGACGTCCACGGCATCGAGGAGACTTGGATCGCAGACCGCACCGAGCAGCGCCTGGCCGGCCCGCTCAAGGACCTGCAGTGCTCCATCTGTATGAAGGTCCTCGCCAGCAAAGGAAACTTCGAGCGCCACCTCGACTATCATAACTCTTTAAGATGCAACTACTGTTTTGATTACTTCAGCTCCCTCAGGTTCTTAGAGGGTCATCTCACGTTTTCATGTGATAAAAAGAAACTTTTAGGCGATTCGGAGATTTATACCAAGAAAATAAAATGCAATGTGTGTTACAAACCCTTCCACGTCCAGGTCAAACTAGATTGTCATCTGCGCACGCAACACGGTATCAAAGTGAACAAGGAAGCTTCGTCAGGCAAAAAAGAAATCGTCTGTGATTATTGCTTTAAAGTGTTCGAGAATGATTATGCTCTGTCTACACACAAAATTTATCATCGCACTGTTGGATACTATGGATGCCTTTATTGCAAGCGAAAGTTTAACACGATGACTGTATATCGAAAACATAAGAATCACCATTTCGCGCAGCTGAATGTAGACGACCCGACCAAGTGCGAACATTGTGACGAGACATTCGTAGCGTTCAGAGACATGATTTATCATATGAGGGATGTCCATGGTGATGATAAAGACTGGGTGACGATGCCCAAGGAATCGATAGAGGAAACATGCAAAATCTGTAATAAAACATTCTACAATTTGCAAAGACATCTTATGTATCACGAGGAAAACAGGTGCAAAAAATGTGGCGAATATTTCTTTTCTACGGCTGATTTCGATAACCATCTGTGCTCTATAGAAAGCGACGACGAGGAGAACGCTAACGGTGTGGACAGCACCATCGAAAAACCTAAGTACGAGGAGTGCAGCTTCTGCTTTAAACCTACCACCAGGAAAAGCTCTAAAGCGATGCACGAACACATCCACAAGGGCTCGGGTTCTATATCGTGTAGGTTCTGTGTGCTCAAATTCAAAACAATGGACGCGTTTAACATCCATGCATTCTCACACCGAAGCAGAAAATATAACAAGAAGCCCATAAAGTGCAAGAAATGTGGTGAAAAATTCGTTAAGTATGGGCTTTTTATAAAGCACATGAAACTCGTGCATAAGTCGTTGAAGAAGATGCATTATAGAGCCATAGTGAAGCCGGAGCCGTGCGTGGTGTGCGGCGAACATTTCCCCAACCTGCACAACCACTACCGCGCGCACTTGCTCAACCAGTGCCAGTTGTGTCACAAATACTTCACATCCTCTAAACTGTTCTCAATGCACGAATGTGACAAAGAAGACTCCGATCCTTCTAAAGTGTTCGTTTGTGATGCAAAGTTGAACGAACTGATAAACTCGTACGTCCCTAAAGATTTGAAAGACGATGAAAAATATTATGGCAACACTGACGACGAAGAAGAGGAAGAAGATGAAGTTTTTCAGGTGTGCGGTGAAGATGAAGAGAGTCAAGACGGCAAGGACATTGATATCAAAGACATTGATAttgatgaaaataatataaccAGCCAACCGTTGTCTATCCAATCACCCATTATATCTGATGTGTTGTCACTCTACCAGAAGGAAATGAATCCTGAAGTCGTGGACGACAATATAGTGAACTTAGCCGATGATGATTCTGACGTGGACCACGTAGACCAGAATCATACAGACACTATAGTTATTGATGATGACGATTGA
Protein Sequence
MALKLGKCRLCLKLGDFYSIFTVDNSLQLAEMAMECARIKIYDGDGLPDKVCSECIQKLSSAYIFKQQCERADQELRRNYVPPPGFSISPPPPTRQSSDSAFSNHTDSSNLTKPSSSFEEKISPATRTRKRSVESDGNVSMGGQSSDFRPTSSKRIEELKNSQKKRPRLQSENTSQPDSDYEDNSGSYVPETDSDEPLIKNSFKCKSCPKQFTTLRSLANHTRIHTKSNSKTLDVDSVVDEPKNSIEDAADVEDKLSCDKCGKTFKLKIMLKRHSDVCLKTPVKSPQKELLISLAPIDAKPNAPQPTVPAVTTIPCEYCVATFKTQDNLAKHMKVVHAAVLKREAEANRKVPVPCLYCDLMFDDYHQHNAHFVECPKLDESKPYVCPVCDKFTSRRTSYYQHLRNMHFEPRVSYVEPEIEMHEYHECRVCSKKLASKEQLIKHLSAHVSNIQDDGTLDNDRDDADSIKSVQSNTYPAGGPLKCDVCDKEFKYKKALLTHQQRFHTDTPVEVKVEPPDKASTSLLSEKQYRSDSESSQEEEDNTCDICEKHFSYKRLLLHHKRTKHNMSSGHKRAKIYLKDCSVRCLICDLQMKVGDINEHNQTHIAKNMKPRNLYTCAECEATFKACSALATHIKLVHRLKQQVEINTVNPSDFCEVVVTKSEPLDWIQSHNDFGEVPIEQDGKPLVDLSGFTCPICGKKMPTLISLKRHVNWHTNVGKNLEKKYECFVCKEAFRFQCHYKLHMREHYTDTALDPRHLTCPICGRKSKHLRAAQAHMTYHKQTRFQNKDYQCSICERVFQHRKVYLSHMAIHYKRGESVQNTIVGSVLPNNVDKNTFDGTHTCMHCGKICDSENSLKHHLIWHTSKTFLYGARHECTICKVKFTNKKRLELHTRTHYEDDNGPYKCNICGKGYTDEGYFKKHVKGHNFDHQSHKKRIEKIRKDKVKCPICSRYYKDLIKLIRHLRRTHPESKMIKTDPDAPPQPYFSCKLCAKVFLDERRLQAHEEAHLRKPEFFKCKFCGKKTISLKNHRVHIKGHLTQKYLDNPLKCPHCEETFGRGYDLHYHVRDVHGIEETWIADRTEQRLAGPLKDLQCSICMKVLASKGNFERHLDYHNSLRCNYCFDYFSSLRFLEGHLTFSCDKKKLLGDSEIYTKKIKCNVCYKPFHVQVKLDCHLRTQHGIKVNKEASSGKKEIVCDYCFKVFENDYALSTHKIYHRTVGYYGCLYCKRKFNTMTVYRKHKNHHFAQLNVDDPTKCEHCDETFVAFRDMIYHMRDVHGDDKDWVTMPKESIEETCKICNKTFYNLQRHLMYHEENRCKKCGEYFFSTADFDNHLCSIESDDEENANGVDSTIEKPKYEECSFCFKPTTRKSSKAMHEHIHKGSGSISCRFCVLKFKTMDAFNIHAFSHRSRKYNKKPIKCKKCGEKFVKYGLFIKHMKLVHKSLKKMHYRAIVKPEPCVVCGEHFPNLHNHYRAHLLNQCQLCHKYFTSSKLFSMHECDKEDSDPSKVFVCDAKLNELINSYVPKDLKDDEKYYGNTDDEEEEEDEVFQVCGEDEESQDGKDIDIKDIDIDENNITSQPLSIQSPIISDVLSLYQKEMNPEVVDDNIVNLADDDSDVDHVDQNHTDTIVIDDDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01502316;
90% Identity
iTF_01360905;
80% Identity
-