Basic Information

Gene Symbol
Hivep2
Assembly
GCA_034640455.1
Location
CM067950.1:3202767-3204593[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 9.3e-06 0.00075 19.9 0.3 2 23 237 258 236 258 0.97
2 13 5.9e-05 0.0048 17.3 4.3 1 23 264 286 264 286 0.91
3 13 1.4e-05 0.0011 19.3 1.8 2 23 292 313 291 314 0.95
4 13 9.3e-06 0.00075 19.9 0.7 1 23 326 348 326 348 0.99
5 13 4.5e-07 3.6e-05 24.0 1.9 1 23 354 376 354 376 0.97
6 13 5.4e-06 0.00043 20.6 1.7 1 23 382 404 382 404 0.98
7 13 0.0026 0.21 12.2 0.4 1 23 410 432 410 432 0.99
8 13 0.00022 0.018 15.5 0.2 3 23 440 461 438 461 0.92
9 13 1.2e-05 0.00099 19.5 1.3 1 23 467 489 467 489 0.98
10 13 7.9e-05 0.0063 16.9 4.7 1 23 495 517 495 517 0.98
11 13 4.5e-06 0.00036 20.9 0.4 1 23 523 546 523 546 0.96
12 13 3.8e-05 0.003 17.9 3.4 1 23 552 574 552 574 0.97
13 13 5.9e-06 0.00047 20.5 4.6 1 23 580 602 580 602 0.98

Sequence Information

Coding Sequence
ATGAGCAATATTCGTTCAAATTTTCCACCAGAGAATGAGGCCAaggaaattaatgaagaattcTCCGATCCCCAAGAGAAGGGTCCTCCACGAACTTCCCATGTCAACGAAAAGGCGGAGGTGTACGTAATCGATTTGCGACATGATCTCGAGAATAATAAGAATAATCCATACAAATATTTCTTAGTATACATAGAAGCCTATTCCCACTATACTGTGCTGAAACCCCTGAGACTGAATAATGAAGAAGAAATTGCGGAGAACCTCctagatattttttccatcatagGATGTCCAGTCATAATCAACTACTACAATAGCAGTATTAACAAGAACTCTGAAAAACTATCAGAAGTGCTAGGAGCCTACAAAATACCCATCTTCAACGTAAAAGTGGAAGAAAACACCAACAAAGAAGGCTCGATATCTCTGGGAAACCATTTGAAGGAGCAATTGTTCGATTGGAGTAGGGAAAATCCGAACAGCCTCCTCCAAATCGGTCTCAAATCTCTCCAGATGACTACAAATAATAGAATCAACGAACTAACAAATAAATCCCCATTCCAACTATTGTTCAATCAATTGTTAGTTCTCAACACTGTCAAATATTCTCCAAACACCACCGAAACCAAGAAACTCGTGACCAATTCCAAATCTCCCCGGCCACGTCCCAATGCCAAGCAATCCCCAAAGTCCTCCTCAAGCATCCCCTGCCCCTATTGCTCTCTGAAATTCACCTTCCCAAGTGTCTTAAAACGTCACCTGCGATCTCACACAAATGAGCGCCCCTACGTCTGtgaaatttgcaataaaacgTTCAAGCAATCGGGCCACCTGAGCCAGCACTGCTTGAGCCACGCCTTCCCGACCTCCCAGTGTCCGATCTGCAGTACAAAATTCGAATCCCGGGACCAATTGAAAGCCCACTTGTCCAGACACCACAGGAATAAACGGGGAATACAGAGCAAGCCGATATTTCAGTGTGACAGTTGCAAGAAAGTCTTCACGATAAAAAGTGTCTTGGAGCGACACATCCTGACGCACACCCACGAGCGTCAGTTCGACTGCAAAATCTGTGGAAAGAGATTCAAGCAGGCAGGACACCTGAAGTCTCACACGCTGGTTCATACCGGGGAGAAGAAGTTTGTATGTTCGATATGCTCAAAACGTTTTACACTCTCCAACAGCCTCAAGAAGCACATGTACGTTCACAACGGGGAGAAACCTTATCAGTGCGATGTGTGTGGGTCCAGGTTCCTCGAGAGAAGAAATTTGAACGGTCACTTGATGACCCACACGAATGAGAGACCCTTCGGCTGTAAAATATGTGATAAACGTTACACTTTGGCGGACACATTGAGGAGACACGTCAGTGCAGCTCACGAGAATGGGAGGACTTATCAGTGTGAGATCTGTGCGAAGATGTTCAAACAATTGGCGCATCTGTCGGTTCATAAGAAAGTTCATACAGATGAACGGCCCTTTCAGTGTCACCTTTGTGATAAAAACTTTAAACATAAGAATGTGCTCAAGAGCCATCTGGCTATTCATGCTAATGTGAGACCCTTTGAGTGCGATGTCTGCAAGGCTACCTTTGTCAGGAAGACTAATCTCCAGACACATATCACGTCCGCGCACATGAATGAACGACCGTATTGTTGTAATATTTGTAACAAGAGGTTTAAACAGATTAGTCATTTGAATGGACATGTTATTGTGCATAGTAACTCTATGCCATTTCAGTGTGATTATTGTGAGAGGAGATGTAACAGACTGGATAATCTGAAGAAGCATATGAAGCTGCATGAGAAGAATAAAGGGGTATGA
Protein Sequence
MSNIRSNFPPENEAKEINEEFSDPQEKGPPRTSHVNEKAEVYVIDLRHDLENNKNNPYKYFLVYIEAYSHYTVLKPLRLNNEEEIAENLLDIFSIIGCPVIINYYNSSINKNSEKLSEVLGAYKIPIFNVKVEENTNKEGSISLGNHLKEQLFDWSRENPNSLLQIGLKSLQMTTNNRINELTNKSPFQLLFNQLLVLNTVKYSPNTTETKKLVTNSKSPRPRPNAKQSPKSSSSIPCPYCSLKFTFPSVLKRHLRSHTNERPYVCEICNKTFKQSGHLSQHCLSHAFPTSQCPICSTKFESRDQLKAHLSRHHRNKRGIQSKPIFQCDSCKKVFTIKSVLERHILTHTHERQFDCKICGKRFKQAGHLKSHTLVHTGEKKFVCSICSKRFTLSNSLKKHMYVHNGEKPYQCDVCGSRFLERRNLNGHLMTHTNERPFGCKICDKRYTLADTLRRHVSAAHENGRTYQCEICAKMFKQLAHLSVHKKVHTDERPFQCHLCDKNFKHKNVLKSHLAIHANVRPFECDVCKATFVRKTNLQTHITSAHMNERPYCCNICNKRFKQISHLNGHVIVHSNSMPFQCDYCERRCNRLDNLKKHMKLHEKNKGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

90% Identity
-
80% Identity
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