Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.00083 38 7.3 0.1 14 47 91 125 80 130 0.76

2 4 0.00045 21 8.2 0.0 21 44 127 150 123 155 0.90

3 4 0.00029 14 8.8 0.1 21 45 155 179 151 184 0.88

4 4 0.00045 21 8.2 0.1 21 45 184 208 178 215 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.00083	38	7.3	0.1	14	47	91	125	80	130	0.76
2	4	0.00045	21	8.2	0.0	21	44	127	150	123	155	0.90
3	4	0.00029	14	8.8	0.1	21	45	155	179	151	184	0.88
4	4	0.00045	21	8.2	0.1	21	45	184	208	178	215	0.87

Coding Sequence: ATGTGGGGAGAACTCCAGCAGGGAGGTCCCGGCCGAGGTGCAACAAGGGCACCAATATGGGGTGAAGCAGCCACACAGCATGTTCGTGAGCTGTGGCAGGAGTTCTTGCTGCCACTTAGCCATGCCCCTCCACCCCCTAGTGCTACACCTGTCACTACCACTGCACCCACCACCTCTCCCAGTAGCCCTACGGATTTGGACGAGCAGCAGTCTTGTGTCATGTGCCTCAAGGGCACACCTCCCCCTGCCAACAGTACACCCTCCCCTTCCAGCAGTACTTCACGTTCACATACAGGAGATCGCCCATTTAGTTGTGATGTATGTGGCAAAGGCTTCACTCAGGCAGCACATCTGACGAGGCACACCAGAGTGCATACAGGAGAGAAGCCATTTTCGTGTGGTGTGTGTGGTAAATGTTTCTCACAATCTGGAGATTTGACTCGTCATGCTCGTGTACATACCGGCGAGAAGCCATATTCGTGTTCCGTGTGCCTGAAACGATTCTCACAGTCTGGTGACCTCAGCCGACATACTAGACGGGCCCACCCTGGGGAGAATCccttttcttgtgcagtgtgcCTCAAGAGTTTCTCGCAGTCAGGAGGTCTGACACGACATACACGAGTTCATGCGACTACTCCTTCACCTACTCAGTCCTCAGGGACATCACCACAGAGTGAACAAGCAAGACAGTTCTTCCCTGACGTAATGTCGCCACCTTGA
Protein Sequence: MWGELQQGGPGRGATRAPIWGEAATQHVRELWQEFLLPLSHAPPPPSATPVTTTAPTTSPSSPTDLDEQQSCVMCLKGTPPPANSTPSPSSSTSRSHTGDRPFSCDVCGKGFTQAAHLTRHTRVHTGEKPFSCGVCGKCFSQSGDLTRHARVHTGEKPYSCSVCLKRFSQSGDLSRHTRRAHPGENPFSCAVCLKSFSQSGGLTRHTRVHATTPSPTQSSGTSPQSEQARQFFPDVMSPP

Sequence clustering based on sequence similarity using MMseqs2