Basic Information

Gene Symbol
-
Assembly
GCA_946251825.1
Location
CAMIUB010000082.1:1762715-1766564[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.00035 0.053 15.0 0.4 1 23 115 138 115 138 0.95
2 14 0.00035 0.052 15.0 0.1 3 23 145 166 144 166 0.94
3 14 8.5e-06 0.0013 20.1 2.8 2 23 177 199 176 199 0.96
4 14 0.00013 0.02 16.3 1.8 2 23 244 266 243 266 0.96
5 14 0.00039 0.059 14.9 3.5 3 23 426 446 424 446 0.96
6 14 9.1e-06 0.0014 20.0 3.5 1 23 452 474 452 474 0.98
7 14 4.4e-05 0.0065 17.9 2.4 1 23 480 502 480 503 0.96
8 14 4.6e-07 6.9e-05 24.1 1.1 2 23 516 537 516 537 0.97
9 14 0.00077 0.11 13.9 0.2 2 23 543 564 542 564 0.96
10 14 2.7e-06 0.0004 21.7 1.8 1 23 570 592 570 592 0.96
11 14 5e-05 0.0074 17.7 3.2 1 21 598 618 598 620 0.94
12 14 7.4e-07 0.00011 23.4 0.8 1 23 626 648 626 648 0.96
13 14 2e-06 0.0003 22.1 3.0 1 23 654 676 654 676 0.99
14 14 2.1e-05 0.0032 18.8 0.1 1 23 681 704 681 704 0.90

Sequence Information

Coding Sequence
ATGGATTTCGATATCGAAAAAATGTGCAGGGTTTGTCTTAAGACCAATTTGGAGTCCGTATTGTTATTCGAAGAGCCAAAGAAAATCGGTGGGGTCAGTATTTGTGACATGATTTCAGAACTTACGATTTACAAGGTCCACCGGCATGATGATTTCCCACATCTTATTTGTTATGAATGCATGGAACGAGTTGAAAGTGCTTATTCTTTCAAAAAGGATTTTGAGCAATCTCATCGTAAACTTGTTACATATTTGGATTCAATCAATAAATACCAAGCAGTTGCTGATATAAAACCCATACCCACTGAAGAAAAAAGCACCCAAACCATAGATTCCACATTGTATCCATGCGAAAAGTGTGATAAAAAATTTATCAAATATGAGCGTTTGCGGGAACACCGAGCTATTGCACACAAAGGGTCGGCCAATCTGTGTCGAATATGTAATAAAGCATTCAACCGCCTGGCAGGTTTAAAAAGTCACATAAGTGCTGCACATCCCGAAATTGGTTACCACAACTCGTCCAACCAGTGTTATGTTTGTAATAAAATGTTCACACGCAGAGATCACGTTACCCGTCACATAAGAAATGTTCACAAAATCGAAACTTCTGAAATTGCCCTTGGAATAGAAACAGCATTAATGGACAAGGATGGAGATCCTTCAATATTCGAAGAGGAAGAATGTAACGCAGATGGTGTAATAAAAGGAGAGCCCAAGTCATTTGTCGAATGTCTTGTGTGTTACAAACATTTTTCAAGTAAAAACCGACTCAATCGTCACATGATAACCATTCACCAACTAGATACTACCCACATTCTCAAGCAGGAGCAAAATAATGAAATAAACGCATTTGAAAATGAATTGGAGTTGCTCGCTGAACCCGAAGCATATAGAAACTACTCAAATGAAGATGATGGAGAAATATCAAACGATTTTGATAACGAAGGTGGTAGTGGTGGTGGTCAGGATGAAGATGATGATGACGAGGAAGAGGAAAATGGTGACAATGATGATGGTTTAGACACGGAAGAAGATGAAGCTTTTAAGAATACTGAATTTGTAGCAGCTAACAGTTTTATTAAATGTGAAGCAGAAATAACAGAATTGCAACCTCCACAACCTGAAGTGGTAAATAAAATTACAACTATTAAACAAGAAAAGGCAGAATTCAACTTAACCGAAAGCATTTACACTCCCCCCAAGCCAGAAAAACTTGCAACAAAAGAAACAACTTTTGATTGCTTCCATAAAATACAAGATGGAAAATACGGATGTAATTTGTGTGAGAAAACCTTTAAGTCTTCTTATCACGTCAAAAGACATTTCTTATCACACACCCAAGAAAAAGCATTCCAATGTACGTTGTGTGAGATGCGATTTAATAGAGCTGATCATCTAAAAAATCACATGACAAAACATAACCCAGTTAAGCCATTCCAATGTGATAGCTGCGGTGCAAGTTATGGTCGCGCAGATCACCTTAAACGACACAGAGAAATGCATCATTCAAATGATCCAAATAGTACGCCAATCAAAGGCGAAGTTTGTGAATACTGTAACAAATCTTACAGTTCTAAAGCTTATCTACAAAAGCATATGCTAAAGCACACAGAAAAATGTTGGAAATGTAAACTTTGTTCGGTTGTATTTGAAACAAGTGAAGCCCTAAAGGAGCATGGCAAATCACACAGCAAAGATAAACCATTTTTGTGCTCAGAATGTGGTTTATGTTTCCCAAGGAAAAATTATCTTATTATTCATATGCGAAGGCACAATGGTGAACGACCGTACAAATGTCAATATTGCGATAAGGGTTTTCCACGTTCCACCGACTTAAAAGCACATGAAAAATGTcatactggagagaaaacacacttttgcaacgtctgtggcaaaggttttccccgaccatacaaattgtcagtacacatgcgaattcataccggcgaaaaaccctatcagtgtatgcattgtccaaaagcttttgctcagtgcaacgacttgaaagcacatattcgaaggcacactggagaaagattcaggtgtgaaatatgtggggctggatttatacaaaaatacaatttgacccaacacaAAGCTGATGCTCATGGCATTATAAATGAGTCGCGTTTAGGTCGAGTAGCTAAAATACCTATTGCCGAACCAATTGGAGAGACTATGACCCAAGTTTTAAATGATTCTGGAGAGGATAAATTGCAAATGGGGCTTACGACAAGCCTGATGTTCCGTGGTGTGGCGCTTCATTAA
Protein Sequence
MDFDIEKMCRVCLKTNLESVLLFEEPKKIGGVSICDMISELTIYKVHRHDDFPHLICYECMERVESAYSFKKDFEQSHRKLVTYLDSINKYQAVADIKPIPTEEKSTQTIDSTLYPCEKCDKKFIKYERLREHRAIAHKGSANLCRICNKAFNRLAGLKSHISAAHPEIGYHNSSNQCYVCNKMFTRRDHVTRHIRNVHKIETSEIALGIETALMDKDGDPSIFEEEECNADGVIKGEPKSFVECLVCYKHFSSKNRLNRHMITIHQLDTTHILKQEQNNEINAFENELELLAEPEAYRNYSNEDDGEISNDFDNEGGSGGGQDEDDDDEEEENGDNDDGLDTEEDEAFKNTEFVAANSFIKCEAEITELQPPQPEVVNKITTIKQEKAEFNLTESIYTPPKPEKLATKETTFDCFHKIQDGKYGCNLCEKTFKSSYHVKRHFLSHTQEKAFQCTLCEMRFNRADHLKNHMTKHNPVKPFQCDSCGASYGRADHLKRHREMHHSNDPNSTPIKGEVCEYCNKSYSSKAYLQKHMLKHTEKCWKCKLCSVVFETSEALKEHGKSHSKDKPFLCSECGLCFPRKNYLIIHMRRHNGERPYKCQYCDKGFPRSTDLKAHEKCHTGEKTHFCNVCGKGFPRPYKLSVHMRIHTGEKPYQCMHCPKAFAQCNDLKAHIRRHTGERFRCEICGAGFIQKYNLTQHKADAHGIINESRLGRVAKIPIAEPIGETMTQVLNDSGEDKLQMGLTTSLMFRGVALH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00427485;
90% Identity
iTF_00335287; iTF_00427485;
80% Identity
-