Basic Information

Insect: Cyclargus thomasi
Gene Symbol: -
Assembly: GCA_026546445.1
Location: JAOTAV010019425.1:12535-20641[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 32 6.1e-07 4.4e-05 24.0 2.0 1 23 194 216 194 216 0.99

2 32 0.0022 0.16 12.8 0.8 2 20 268 286 267 288 0.91

3 32 0.0012 0.089 13.6 0.2 2 23 314 336 313 336 0.96

4 32 0.0012 0.085 13.7 0.5 1 23 387 409 387 409 0.97

5 32 0.031 2.2 9.2 0.4 1 23 430 452 430 452 0.98

6 32 0.00058 0.042 14.7 0.4 2 23 493 515 492 515 0.94

7 32 0.0017 0.12 13.2 4.1 2 23 569 591 569 591 0.97

8 32 0.00023 0.016 15.9 1.8 1 23 641 664 641 664 0.97

9 32 0.00067 0.048 14.5 0.5 2 23 720 741 719 741 0.96

10 32 0.0018 0.13 13.1 5.1 2 23 753 774 752 774 0.97

11 32 0.14 10 7.1 2.2 2 23 786 807 785 807 0.96

12 32 0.011 0.79 10.6 1.7 1 23 817 839 817 839 0.98

13 32 0.0017 0.12 13.2 4.5 2 23 869 890 869 890 0.96

14 32 0.00026 0.019 15.7 1.9 1 23 901 923 901 923 0.98

15 32 0.014 0.99 10.3 3.1 1 23 931 953 931 953 0.97

16 32 0.0025 0.18 12.7 0.2 2 23 973 995 972 995 0.97

17 32 3 2.1e+02 3.0 0.7 1 23 1013 1035 1013 1035 0.88

18 32 0.12 8.4 7.4 3.7 1 23 1042 1064 1042 1064 0.97

19 32 0.00059 0.043 14.6 2.7 2 23 1075 1097 1074 1097 0.95

20 32 0.021 1.5 9.8 0.1 2 23 1120 1141 1119 1141 0.95

21 32 0.13 9.4 7.2 0.4 2 20 1145 1163 1144 1164 0.93

22 32 6.1 4.4e+02 2.0 3.2 2 23 1184 1206 1183 1206 0.90

23 32 0.0021 0.15 12.9 0.3 3 23 1223 1243 1221 1243 0.95

24 32 7.6 5.4e+02 1.7 2.9 5 23 1253 1271 1250 1271 0.93

25 32 0.012 0.84 10.5 0.5 2 23 1282 1304 1281 1304 0.95

26 32 2.7 2e+02 3.1 4.9 2 23 1321 1339 1321 1339 0.86

27 32 3.1 2.2e+02 2.9 2.1 2 20 1343 1361 1343 1362 0.89

28 32 7.7 5.6e+02 1.7 1.9 2 19 1385 1402 1385 1406 0.86

29 32 0.25 18 6.3 1.1 2 23 1413 1434 1412 1434 0.93

30 32 0.0035 0.25 12.2 0.1 2 23 1445 1467 1444 1467 0.95

31 32 1.7 1.2e+02 3.7 0.4 3 23 1484 1501 1483 1502 0.77

32 32 0.068 4.9 8.1 3.8 1 21 1504 1524 1504 1525 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	32	6.1e-07	4.4e-05	24.0	2.0	1	23	194	216	194	216	0.99
2	32	0.0022	0.16	12.8	0.8	2	20	268	286	267	288	0.91
3	32	0.0012	0.089	13.6	0.2	2	23	314	336	313	336	0.96
4	32	0.0012	0.085	13.7	0.5	1	23	387	409	387	409	0.97
5	32	0.031	2.2	9.2	0.4	1	23	430	452	430	452	0.98
6	32	0.00058	0.042	14.7	0.4	2	23	493	515	492	515	0.94
7	32	0.0017	0.12	13.2	4.1	2	23	569	591	569	591	0.97
8	32	0.00023	0.016	15.9	1.8	1	23	641	664	641	664	0.97
9	32	0.00067	0.048	14.5	0.5	2	23	720	741	719	741	0.96
10	32	0.0018	0.13	13.1	5.1	2	23	753	774	752	774	0.97
11	32	0.14	10	7.1	2.2	2	23	786	807	785	807	0.96
12	32	0.011	0.79	10.6	1.7	1	23	817	839	817	839	0.98
13	32	0.0017	0.12	13.2	4.5	2	23	869	890	869	890	0.96
14	32	0.00026	0.019	15.7	1.9	1	23	901	923	901	923	0.98
15	32	0.014	0.99	10.3	3.1	1	23	931	953	931	953	0.97
16	32	0.0025	0.18	12.7	0.2	2	23	973	995	972	995	0.97
17	32	3	2.1e+02	3.0	0.7	1	23	1013	1035	1013	1035	0.88
18	32	0.12	8.4	7.4	3.7	1	23	1042	1064	1042	1064	0.97
19	32	0.00059	0.043	14.6	2.7	2	23	1075	1097	1074	1097	0.95
20	32	0.021	1.5	9.8	0.1	2	23	1120	1141	1119	1141	0.95
21	32	0.13	9.4	7.2	0.4	2	20	1145	1163	1144	1164	0.93
22	32	6.1	4.4e+02	2.0	3.2	2	23	1184	1206	1183	1206	0.90
23	32	0.0021	0.15	12.9	0.3	3	23	1223	1243	1221	1243	0.95
24	32	7.6	5.4e+02	1.7	2.9	5	23	1253	1271	1250	1271	0.93
25	32	0.012	0.84	10.5	0.5	2	23	1282	1304	1281	1304	0.95
26	32	2.7	2e+02	3.1	4.9	2	23	1321	1339	1321	1339	0.86
27	32	3.1	2.2e+02	2.9	2.1	2	20	1343	1361	1343	1362	0.89
28	32	7.7	5.6e+02	1.7	1.9	2	19	1385	1402	1385	1406	0.86
29	32	0.25	18	6.3	1.1	2	23	1413	1434	1412	1434	0.93
30	32	0.0035	0.25	12.2	0.1	2	23	1445	1467	1444	1467	0.95
31	32	1.7	1.2e+02	3.7	0.4	3	23	1484	1501	1483	1502	0.77
32	32	0.068	4.9	8.1	3.8	1	21	1504	1524	1504	1525	0.95

Sequence Information

Coding Sequence: ATGGCTCTCAAGCTCGGAAAATGTAGACTTTGTCTCAAACTTGGAGATTTTTGCTCCATCTTCACCGCAGATAACAATGTTCAACTCGCTGAAATGGTTATGGAATGTGCCCGAGTAAAAATATATGAAGGAGATGGACTACCGGATAAAATATGCAATGAGTGCATACAGAAACTCAGTGGTGCTCATATCTTTAAACAGCAGTGTGAACGCTCAGACCAAGAATTACGACGAAACTATGTGCCTCCACCAGGATTTAGTATATCACCCCCTCCGCCGACTCCGACGAACAGACAAAGCAGCGATTCCGCGTTTTCTTCACTTGCTCCCGAACCATTGAAACCCTCGTCACCCGTAGAGAGCAAAGTAAAAGCAGCTTCTAGAGGTCGCAAACGAAGCGGCGACAGCATCGACGGCGCGTCAGTCAGTAGTCGCTCCCATGACTACCGCGGGGTCACCAAACGCGTCGACGAGTTGCGGACGACACACAAGAAGAAGGGAAGGTACACGTCGGATTCCGATTACGAGGACACCGGCGCCTTCTACTCCGCCGAAACCGACTCTGACGACGTGTGCGATTACAAATGCAAGGAATGTCCTAAATCTTTCAAAACCCAAAAAAGTCTGTCGGCCCATACCAAGGTGCACAGACGCAAATTCAACCAAGCAAACGTCTCTCAGGAAAATGACAGTCTCGACACGACTTACAATAGTGCCGCCGACGCGAGTTATAACGAACCGACTTCGACCTTCGAGACCTCCAAAAATTTCGACGACGCCATGGACGTGGAGGACAAGCTCTCGTGCGACAAATGCAACAAAACATTCAAATTGAAGATCATGTTGAAACGGCACTCCGAGACGTGCGGTAAAACTCCCACGAAAACGCTCCAAGTCGCCCTGGAGCCACTGGAGCTACCGACCCCCAGCAGTGCGATCACCTGCAAGATGTGCAGCGGCCTGTTCAAAACCGTCGATAATCTCGCGAAGCACATGAGAGTTGTCCACGCGGCCGCGCTACCGAGTGAGCTACAAAAGGAGAAAGTAGTCGAAGCCACCGTCTCCGTGCCGTGTGTTTTTTGTGAGCAATCGTTTGACGAATTCCTAGCCTACAAGACGCATATAGATGAATGCTCAGAAAAGAGGACCCTACAGAGCTTTGATTGCCCACTCTGTCAGCGACCATTGTCGAGAAGACATGCCTACATCGCCCATATCAAGTCCCACTTTTTCCCAACGACAAACACGAGGTTCCCCAACACACCGCTAAAACCAGAAACGCCCACCTTCAAATGTCGTTTCTGCAGCCTCACGCTACCCAGCCAAGAGTTACTGATTATTCATTTGTCTAAGCACATGGCGAATATGGACGACGACCCCAATGAAGCCGGCGACGAAGAATCGAGAGCGAGTACTGTTGAAGATTCGGCGTCCGTACATTCCGAATATAGCGGAAGTGCGCCACCTCGGAAGCTAAGTTGCCGCTACTGTGGCAAACAGTTCACATATGAAAAAGCTCTCGCTACTCACATCGTTAAAAATCACCCGCCGGGCTCGGAGGTCAAAGGCGAGCCACCGGACAAAAACAGCTCATTGCTCAGTGAGGCGAACCAGAGCTTAGATAACACAGGCATGACTGAGGGCATGAACGACACGGGGATGACGGAGTCCGAGTCCGAGGATGAGGAGGGCGAGGACGACAACACGTGTGACATCTGCGAGAAGCAGTTCTCGTATCGTCGCCTGCTGCTGCACCACAAGCGCACCAAGCACAACATAGCCTCCGGCACCAAGCGCGCCAAGATCACGCTTAAGGACTGCACGGTGCGCTGCCTCATCTGCGATATCGAGATGAAAGTGAGTGACATCAACGAGCATAATCAGACACACATATCAGTCAATATGAAACCGAGAAACCTGTACACGTGCACGCTGTGCACCATGACGTTTAAGAGCTGCAGCGGCCTGGCCAACCACATCAAGCTAGTCCACAGACTAAAGCAGCAGGTGCCTAAATTAGACGTCTCCGCCCCCAATCCGGCGGATTTTTGTGAGGTCGTTGTGACAAAGGCGGAGCCCCTGGACGACGTTCAGGGTCACAACGGCATTTCCGAGGCCGCCGCCACCGAAATACCTTTGGTGAACATGGAGGAACTGACTTGCCACATCTGCGGCAAGCAGCTGCCGACGCTCATATCGCTCAAGAGACATGTCAACTGGCACAAGAACGTCGGCAACAACATCGAGAAGCCGATGGAATGCTTTGTATGCAACGAGACATTCAGATTCCAGTGTCACTACAAGATACATATGCGCATTCACTACCACGACACCAACCTGGACCCCAAGTATCTCACCTGCTCCATCTGCAATCGCAAGAGCAAACACCTCCGCGCGGCCCAGATGCACATGAACTACCACAAGCAGACCCGATTCAAGAATAAAGACTACGAGTGTTCCATTTGCAAAAGAATCTTTCAACACCGCAAGGTATACCTCTCGCACATGGCCGTCCATTTCAAAAAGGGCGATAGTGCCACCAACACGATCGTCGGCTCCGAGCTCCCGATGAATGCGGACAAAACTGCATTCGATGGCACCAACACCTGCCACCTCTGTGGAAAGGTCTGTGACTCGGAGTCTTCACTCAAGCATCATCTTATTTGGCACAAATCTAAAACTGTCCTGTTCGGTGCAAGGCACGAGTGCGACATTTGCAGCGTAGTCTTCACTAACAAGAGACGCCTGGAACTCCACTACCGAACCCATTTCGAGGACGACAATGGACCCTTCAAGTGCCACATTTGTGGAAAAGGCTATATAGTGGAGGACTATTGCAAGAAGCACATCAAAGGACACAACTTCGATAATCAGTCGCACAAAAAGCGACTAGAAAAGTTGCGGAAGGACAAGGTAAAGTGTCCGATATGCTCGCGGTACTATCCGGACTTGGTTAGACTGATTCGACATCTGCGACGAACACATCCTGAGAGCAAAATGATAAAAGAGGACCCAGACGCTCCTCCGCCCATGTACCACTCATGTAAACTGTGCGCTAAGGTATTTTTGGACGAAAGAAGATTGCAATCTCACGAGGAAGCACATCTAAGAAAGCCCGAATTCTTTAAGTGCAAATTTTGCGGAAAGAAAACAATATCGCTCAAGAATCACAGGATTCACATAAAGGGACATCTGACCCAAAAGTATATCGACGATCCCCTGAAGTGCCCCCACTGCGACGAGACGTTCAACAGGGGGTACGACTTGCACTATCATCTTCGCGACTCCCACGACATCGTCGAAACTTGGATCGCCGAACGCGGAACCCAGACCCTGGACGGTCCTCTCAAGGAACTCCAATGTGGCGTCTGCTACAAAGTCTTGGCTAGCAAGGGCAATTACGACAGGCACATCGACTACCACAACTCCCTGCGATGCAACTACTGCTTCGAGTTCTTCAACACCTCCCGATTCCTGGAAGGGCATCTCGCCTTCAGCTGCGAGAAAAAGAAGCTCATAGGGGATACCGAGACGTATCCGAAAAAAATTAAGTGCGAAATTTGCTTCAAAGCTTTCCATCTACAAGTGAAACTGGACTGTCACCTTCGGGTCAAACACGACATCAAAGTGTTCAAGGAAAAGTCGGCCGGAAAGAGGGAAATCATCTGCGACTACTGCTTCAAAGTGTTCGAAAATGAGTACGCCCTGAGTAACCACAAACTGTATCATCGCACGATCGGTTATTACGGTTGCATATACTGCGCGAGAAAGTTTAACACGATGACTGCGTATAGGAAACACAAAAATCACCACTTCGCCCAGCTACACGTCGACGATCCGGTGAAGTGCGAGCACTGCGACGAAACGTTCGTCGCCTTCCGGGAGATGATATACCACATGCGGGACGTGCACGGCGACGAAAAAGAGTGGATCATCGAGCCCAAGCCGTCCATCGAGGAGAAGTGCCACATCTGCGAGAAAGTGTTCTTTAACCTCCACCGCCACCTAGTTTACCATGAGGAGAACAGGTGCAAGAAGTGCGGAGAGTACTTCTACTCCACACTTGACTTCGACAACCATCTGTGCCCGATCGACTCCGACGAGGAGGTCGACGAGAGCAGCGGGTTCACCGATCTGCGTCCCAAATACGAGGAGTGCGACTTCTGCTTTAAGCCTACCACCCGAAAGTACTCCAAGAAGCTGCACGACAACATGCACCGCGGGTCGGGCGCTATATCCTGCCGGTTCTGCTCCCAGAAATTCAAGACGATGGACGCATTCAACATTCACGCCTTCTCGCACAGGAGCAGGAAGTACAAGCTGAAACCGATCCGGTGCAAGATGTGCCCCGAGGCGTTCGTCAAGTACGGGCCGTTCATGAAGCACATGCGGGACGTGCACAAGTCCCTGAAGAAGATGCACTACCGTACGCGGGTGAAGGCTGAGCCGTGCGTCGTCTGCGGGCTGAGCTTCCCCAATCTGCACAACCACTACCGCGCTCACATGGCCCACAAGTGTCCCTCGTGCCGCAAGTATTTCACTTCTAGCCGCGCGTTTGCCCAGCACCAGTGCGACCAGCCCGACGCCGACCCCAGCAAGGTGTTCACGTGCGACGCTGACCTCAACCGGCTAATCAACGAGTACGAGCCCAAGGACGAGGAGGACGACGAAAAGTACTACGGCTACGACGACGACGGCGAGCCGCCGCCGGAGCCCGAGCCCGCACGCCCACCGCGTCCGCGGGGCCGCCCCGTCAAGCTGGCCAAGGCCCGCCCGAAACCGGTCGGCCGGCCGCCCGGGCCGCGGACGTACAGGAACCCGAAGCTCGTGAAGCAGATCTGGAAAGGGCTGGGCAGGTCGGTGGCGGCTGCTCGGAGCTCGCAGGATGAGGACAGCCAGAACTCCATGGACCCCGACGAGGGCCAGCTGCACGAGATGGTCCATGCGCCCATCATATCCGACGTGCTGTCGCTCTACCAGAAAAATGAGAAGAAGAAAGGTAAAAACGACGAAGACGAGGACAGTGACGTCGTCATGTTGTCCGACGACGACTCCGGGCCCAAGCGAGTCATACCCGTCGTTGTAGTCGACGACGATTGA
Protein Sequence: MALKLGKCRLCLKLGDFCSIFTADNNVQLAEMVMECARVKIYEGDGLPDKICNECIQKLSGAHIFKQQCERSDQELRRNYVPPPGFSISPPPPTPTNRQSSDSAFSSLAPEPLKPSSPVESKVKAASRGRKRSGDSIDGASVSSRSHDYRGVTKRVDELRTTHKKKGRYTSDSDYEDTGAFYSAETDSDDVCDYKCKECPKSFKTQKSLSAHTKVHRRKFNQANVSQENDSLDTTYNSAADASYNEPTSTFETSKNFDDAMDVEDKLSCDKCNKTFKLKIMLKRHSETCGKTPTKTLQVALEPLELPTPSSAITCKMCSGLFKTVDNLAKHMRVVHAAALPSELQKEKVVEATVSVPCVFCEQSFDEFLAYKTHIDECSEKRTLQSFDCPLCQRPLSRRHAYIAHIKSHFFPTTNTRFPNTPLKPETPTFKCRFCSLTLPSQELLIIHLSKHMANMDDDPNEAGDEESRASTVEDSASVHSEYSGSAPPRKLSCRYCGKQFTYEKALATHIVKNHPPGSEVKGEPPDKNSSLLSEANQSLDNTGMTEGMNDTGMTESESEDEEGEDDNTCDICEKQFSYRRLLLHHKRTKHNIASGTKRAKITLKDCTVRCLICDIEMKVSDINEHNQTHISVNMKPRNLYTCTLCTMTFKSCSGLANHIKLVHRLKQQVPKLDVSAPNPADFCEVVVTKAEPLDDVQGHNGISEAAATEIPLVNMEELTCHICGKQLPTLISLKRHVNWHKNVGNNIEKPMECFVCNETFRFQCHYKIHMRIHYHDTNLDPKYLTCSICNRKSKHLRAAQMHMNYHKQTRFKNKDYECSICKRIFQHRKVYLSHMAVHFKKGDSATNTIVGSELPMNADKTAFDGTNTCHLCGKVCDSESSLKHHLIWHKSKTVLFGARHECDICSVVFTNKRRLELHYRTHFEDDNGPFKCHICGKGYIVEDYCKKHIKGHNFDNQSHKKRLEKLRKDKVKCPICSRYYPDLVRLIRHLRRTHPESKMIKEDPDAPPPMYHSCKLCAKVFLDERRLQSHEEAHLRKPEFFKCKFCGKKTISLKNHRIHIKGHLTQKYIDDPLKCPHCDETFNRGYDLHYHLRDSHDIVETWIAERGTQTLDGPLKELQCGVCYKVLASKGNYDRHIDYHNSLRCNYCFEFFNTSRFLEGHLAFSCEKKKLIGDTETYPKKIKCEICFKAFHLQVKLDCHLRVKHDIKVFKEKSAGKREIICDYCFKVFENEYALSNHKLYHRTIGYYGCIYCARKFNTMTAYRKHKNHHFAQLHVDDPVKCEHCDETFVAFREMIYHMRDVHGDEKEWIIEPKPSIEEKCHICEKVFFNLHRHLVYHEENRCKKCGEYFYSTLDFDNHLCPIDSDEEVDESSGFTDLRPKYEECDFCFKPTTRKYSKKLHDNMHRGSGAISCRFCSQKFKTMDAFNIHAFSHRSRKYKLKPIRCKMCPEAFVKYGPFMKHMRDVHKSLKKMHYRTRVKAEPCVVCGLSFPNLHNHYRAHMAHKCPSCRKYFTSSRAFAQHQCDQPDADPSKVFTCDADLNRLINEYEPKDEEDDEKYYGYDDDGEPPPEPEPARPPRPRGRPVKLAKARPKPVGRPPGPRTYRNPKLVKQIWKGLGRSVAAARSSQDEDSQNSMDPDEGQLHEMVHAPIISDVLSLYQKNEKKKGKNDEDEDSDVVMLSDDDSGPKRVIPVVVVDDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00744973;
90% Identity: iTF_01217685;
80% Identity: -