Basic Information

Insect: Culex quinquefasciatus
Gene Symbol: PRDM5
Assembly: GCA_015732765.1
Location: NC:210476059-210479494[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 0.0027 0.076 13.3 0.3 1 23 47 69 47 69 0.93

2 22 0.00043 0.012 15.7 0.6 1 23 78 101 78 101 0.98

3 22 0.01 0.28 11.4 0.1 2 23 111 133 110 133 0.94

4 22 1.9e-05 0.00053 20.0 0.6 1 23 140 162 140 162 0.98

5 22 0.00038 0.011 15.9 0.6 1 20 167 186 167 188 0.92

6 22 0.021 0.61 10.4 0.6 2 21 195 214 194 215 0.93

7 22 0.076 2.2 8.7 0.4 1 23 290 313 290 313 0.97

8 22 0.0013 0.037 14.2 1.4 1 23 517 540 517 540 0.94

9 22 3.2e-05 0.00091 19.3 2.1 3 23 555 576 554 576 0.96

10 22 0.96 27 5.2 0.3 2 22 587 607 586 607 0.93

11 22 0.0065 0.19 12.0 1.3 1 23 621 643 621 643 0.98

12 22 0.0084 0.24 11.7 3.3 1 23 649 672 649 672 0.96

13 22 0.0087 0.25 11.6 0.3 2 23 694 716 693 716 0.93

14 22 0.0022 0.063 13.5 1.4 1 23 737 760 737 760 0.95

15 22 0.32 9.1 6.7 2.2 1 23 775 798 775 798 0.95

16 22 7.2e-05 0.0021 18.2 1.8 1 23 840 862 840 862 0.96

17 22 0.042 1.2 9.5 1.6 2 23 869 891 868 891 0.95

18 22 4e-05 0.0011 19.0 3.6 2 23 899 920 898 920 0.96

19 22 0.00031 0.0089 16.2 6.5 1 23 925 948 925 948 0.93

20 22 0.00019 0.0055 16.8 1.4 3 23 958 978 956 978 0.97

21 22 8.1e-06 0.00023 21.2 1.1 1 23 984 1008 984 1008 0.97

22 22 0.29 8.4 6.8 1.3 1 23 1014 1037 1014 1037 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	0.0027	0.076	13.3	0.3	1	23	47	69	47	69	0.93
2	22	0.00043	0.012	15.7	0.6	1	23	78	101	78	101	0.98
3	22	0.01	0.28	11.4	0.1	2	23	111	133	110	133	0.94
4	22	1.9e-05	0.00053	20.0	0.6	1	23	140	162	140	162	0.98
5	22	0.00038	0.011	15.9	0.6	1	20	167	186	167	188	0.92
6	22	0.021	0.61	10.4	0.6	2	21	195	214	194	215	0.93
7	22	0.076	2.2	8.7	0.4	1	23	290	313	290	313	0.97
8	22	0.0013	0.037	14.2	1.4	1	23	517	540	517	540	0.94
9	22	3.2e-05	0.00091	19.3	2.1	3	23	555	576	554	576	0.96
10	22	0.96	27	5.2	0.3	2	22	587	607	586	607	0.93
11	22	0.0065	0.19	12.0	1.3	1	23	621	643	621	643	0.98
12	22	0.0084	0.24	11.7	3.3	1	23	649	672	649	672	0.96
13	22	0.0087	0.25	11.6	0.3	2	23	694	716	693	716	0.93
14	22	0.0022	0.063	13.5	1.4	1	23	737	760	737	760	0.95
15	22	0.32	9.1	6.7	2.2	1	23	775	798	775	798	0.95
16	22	7.2e-05	0.0021	18.2	1.8	1	23	840	862	840	862	0.96
17	22	0.042	1.2	9.5	1.6	2	23	869	891	868	891	0.95
18	22	4e-05	0.0011	19.0	3.6	2	23	899	920	898	920	0.96
19	22	0.00031	0.0089	16.2	6.5	1	23	925	948	925	948	0.93
20	22	0.00019	0.0055	16.8	1.4	3	23	958	978	956	978	0.97
21	22	8.1e-06	0.00023	21.2	1.1	1	23	984	1008	984	1008	0.97
22	22	0.29	8.4	6.8	1.3	1	23	1014	1037	1014	1037	0.96

Sequence Information

Coding Sequence: atgaaacaaaacgCCACTGACTCAGCATTTCTGGTGCAAGAAGGGGCAGAAAACGCTGAAAAGCAGCCCGACCTCAAGCAGGACTCGGACGAGGAAGATTTTCTTCCAACGGAACCAAAACCCGCTAAAAAGCATCCCTTCCAGTGCGAAATATGCGACAAAATTCTCTCGACCAAGCAAAACCTCAAATTCCATGCGATCGTTCACGAAGATCCGACCAACCGGGAAACGTTCCGCTGCGAGATCTGCGAGGGCGTTTTCAAGTCTCGAGTCGGTTTGAAATATCACCTGAAAACGCAGCACGTCCCGGAGAATGAGCGTAAGAAGCTGCCCTGTCCGACGTGCGGACGGATTTTTAAAAGCGACGAGGGCCGGAAGATCCACATGACCATTCAGCACGGCGTCGGCGGGCCGATCTTTAGGTGCAAGGAATGCCCGATGGTATTCGCGCGGAAACCCCACCTAGATCTGCACATGGCAACTCATGGCGCGGGCCAGCACGTTTGCACGACCTGCGGGAAGTCGTACGCCAGGCTGAAGGACCTGTCCCGACACGAGACCACCTGCGGCCTCAAGGAACTATGCTGTCCGCTGTGTGGCAAGCAGCTTCGGACGGAGCAAGCCCTCGAGAATCATCGGAAAAATTGCCGATCGAGCGGTTTGAGGTGTGAAGTCGGTCATGGCGAGAGGCGGGGACGTCCGAAAAAGAGCGGATCTGGCGGCGAGGATGGCAAGGTTCGCATGAGGCGCAGCAAACATGACCGGTTTCTTGGACTGGACCATTTGGCGGATCCATCAGCGCTGGTCGAAGCAGTCGTGGAACCGGCCAGGGTTGAGCCAAAGCTGAAGGAACGCGTTTTGAAGAGATTCCAGTGCGAGCATTGTCCGCTGAAGTTGGCCGGAAAGATTGCGCTGTTGAATCACGGACGCAGACGGCACTGGGAGGCTTTCGGGCTAACGGAGCCGGCTCCCGAAAAGCGAGGACGCAAGCGGACGCATCCGGTGGGACACAAGAGGAAGAGGATTCGCCATCGGCGTAAGATCATCAACTATGTTGACCCTGAGGAATTGCCGGAAGAGGATGAGTGTGACGCAGAGAACGAGGAAGCTGATCCGGTGAAGGCGGAAGATGTTGAACTCGGAGAACCAACGATCGAAGATCCAGTTGAGAACGTGACCATTCCAGAAGACATTAAAGAAAACGTTGTGTACATTGAGGAGAAATTGCAGCCAATTCAAAATGTTGAAGAACAAACACTTGCGGCAAACGACGGCGCCATCAAGGAAGAGATCATGGAGTTTGGCGAGTACGAATTTGGTCACTTCGAGGGTGATTCGACCGAGGAAGAGGCCGCCGACTTTGAAGATGAAACGTTTGAGCACGTTGCGGCTGACCTTGGGCCCTTGATTCCGGAAGAGCCGCCCAGCGATGAAGTGGACACTCTCGATGTTGAACCAGCGAATGATCCACAAATCTGCGACGACCTCGTGATCAAACTGGAAAAGCTAGATTACACCAAGCTGGTTAATCCAAAAAGGACGTTAAAGTACCGTTGTGAAGAGTGCGATAAATCGTACCAGCTTGAGCATAACCTTAAGGCGCACAACGAAAAAGTGCACGGCATCACGGAAGAGCTTGGTGAAGGTGTTTATGCTCGACCCTGTAAGCACTGCGGAAAGAAGTTGAAATCCTGGTCAAGTCTGGTCAAACATTTGAAGGTTTTCCACGCAGAAGGTGTCGACGAATCACAGTTCGTTAAATGTCCGTCGTGTCCTGCAAAGTTTCTTAATCAGGAAGACTTGGACAAGCACGTGTGCACTAGGAGTGGTGTTTGCGAAGGGAAACCAAGGGAGCGTTCCTTCAAGTGTGATCTGTGCCGTAAAAAGTACACTTTCCTCCTTCAATTGGAAGCGCACTATTCCGTGCATCCAGAATATCAGAACTTCAAATGTGACCACTGTTCGAACGGATTCTACAACGAAAGGGAGCTGAACAAGCACAAGAAGAACGCGCACGAACATACGGTGAAGAAGATTCGCCCCTTCAAATCCAAGTACAAAAATCCGTTTCCGAGGACGGAATGCGAACAATGTGGACAAACGTTTGCCTACCGATACCGGCTAGCACTGCATCGGGTCAAGGTACACGGAAGCACGGAAACACCGGTGGCAAACAGACCAGTTCCAAAGACTACGTTTCCACGAAACTTCCCTTGTGATCAGTGCGATAAATCATACCATCTTCAGACTAATCTCACGATTCACAAAGCCAAGGTTCACGGCGTTGGAGAAGCCCCGTCAAAGGATAGGTTAGCCTTTCTGCACACCTGCAAGGTCTGTGAAAAGCAAGTCACAAATTTTGGTGTTCTGGTCTACCATATGAAGTTTAAGCACGGAATAAGCATCGATGAGTCGAAGTTCGTTCAATGCCCGTCGTGTCGAATCAAATTCATCGCCGAAAAAGAAATGGCGGAGCATCTTTGTCTCAAGGGAGTTGTTCGCGAGAGGAAACATCCCTTCAAGTGCAACTTGTGTGATAAAGCTTATGTCACAAAAACAGATCTGGAACACCACTACTCCGCTCATCCGGAATACCACAACGTCAAGTGTGAGCAATGTCCTAGAGGGTTCTACAACGACCGGGAACTCAACCTACACAAGAAACACATGCACAAACCAAAAGATGCCTACGTTGAGTGCAAGATCTGCAATAAGCTGTTCAAAAACCAACGAAACTtgaaacaccaccagcagcttcACATGGATCGCGAGTACTGTTGTGAGCATTGTGGTAAAACGTTTAAAACTTTACATTTGCTGCAATCGCACGTACAATTCATTCACTCGAATCCAAACGATCGACTGATCGCTTGCACAATTTgtgggaaaaaaatcaaaggaaaaACAAGCCTAAAACATCACATGAAAATACACAACAACGATCGACCGTTCAAATGTTCCTTTCCGTCCTGTGGCAAAACCTTCAGTACGAGGGGCGATTTGAACAAGCACGTGCAAAGTCACACAAAGAATTACAAGTACAAGTGCAAGTTCTGCGATTATGGGACTATTTCACGGAAGACAATTCTGCAGCACGAACAGCGGGAACATAATCATAACCGGTTCGCTGAAGTGAATGATTCGTGA
Protein Sequence: MKQNATDSAFLVQEGAENAEKQPDLKQDSDEEDFLPTEPKPAKKHPFQCEICDKILSTKQNLKFHAIVHEDPTNRETFRCEICEGVFKSRVGLKYHLKTQHVPENERKKLPCPTCGRIFKSDEGRKIHMTIQHGVGGPIFRCKECPMVFARKPHLDLHMATHGAGQHVCTTCGKSYARLKDLSRHETTCGLKELCCPLCGKQLRTEQALENHRKNCRSSGLRCEVGHGERRGRPKKSGSGGEDGKVRMRRSKHDRFLGLDHLADPSALVEAVVEPARVEPKLKERVLKRFQCEHCPLKLAGKIALLNHGRRRHWEAFGLTEPAPEKRGRKRTHPVGHKRKRIRHRRKIINYVDPEELPEEDECDAENEEADPVKAEDVELGEPTIEDPVENVTIPEDIKENVVYIEEKLQPIQNVEEQTLAANDGAIKEEIMEFGEYEFGHFEGDSTEEEAADFEDETFEHVAADLGPLIPEEPPSDEVDTLDVEPANDPQICDDLVIKLEKLDYTKLVNPKRTLKYRCEECDKSYQLEHNLKAHNEKVHGITEELGEGVYARPCKHCGKKLKSWSSLVKHLKVFHAEGVDESQFVKCPSCPAKFLNQEDLDKHVCTRSGVCEGKPRERSFKCDLCRKKYTFLLQLEAHYSVHPEYQNFKCDHCSNGFYNERELNKHKKNAHEHTVKKIRPFKSKYKNPFPRTECEQCGQTFAYRYRLALHRVKVHGSTETPVANRPVPKTTFPRNFPCDQCDKSYHLQTNLTIHKAKVHGVGEAPSKDRLAFLHTCKVCEKQVTNFGVLVYHMKFKHGISIDESKFVQCPSCRIKFIAEKEMAEHLCLKGVVRERKHPFKCNLCDKAYVTKTDLEHHYSAHPEYHNVKCEQCPRGFYNDRELNLHKKHMHKPKDAYVECKICNKLFKNQRNLKHHQQLHMDREYCCEHCGKTFKTLHLLQSHVQFIHSNPNDRLIACTICGKKIKGKTSLKHHMKIHNNDRPFKCSFPSCGKTFSTRGDLNKHVQSHTKNYKYKCKFCDYGTISRKTILQHEQREHNHNRFAEVNDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400816; iTF_00400817;
90% Identity: iTF_00400817;
80% Identity: -