Cpip018331.1
Basic Information
- Insect
- Culex pipiens
- Gene Symbol
- -
- Assembly
- GCA_016801865.2
- Location
- NW:7403-10725[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 23 0.068 2.1 9.5 1.7 1 23 47 69 47 69 0.93 2 23 0.0013 0.039 14.9 0.5 1 23 78 101 78 101 0.98 3 23 0.0042 0.13 13.3 0.1 2 23 111 133 110 133 0.94 4 23 3.7e-06 0.00011 22.9 0.6 1 23 140 162 140 162 0.99 5 23 0.0023 0.07 14.1 0.2 1 20 167 186 167 188 0.92 6 23 0.016 0.49 11.5 0.6 2 21 195 214 194 215 0.93 7 23 0.12 3.8 8.7 0.4 1 23 290 313 290 313 0.97 8 23 0.00033 0.01 16.8 1.8 1 23 517 540 517 540 0.94 9 23 0.0091 0.28 12.2 3.6 2 23 554 576 554 576 0.94 10 23 6.3 1.9e+02 3.3 0.1 2 21 587 606 586 607 0.88 11 23 0.0069 0.21 12.6 2.5 1 23 621 643 621 643 0.98 12 23 0.016 0.49 11.5 3.5 1 23 649 672 649 672 0.96 13 23 0.015 0.45 11.6 0.3 2 23 698 720 697 720 0.93 14 23 0.0036 0.11 13.5 1.4 1 23 741 764 741 764 0.95 15 23 0.61 19 6.5 3.0 1 23 779 802 779 802 0.95 16 23 1 31 5.8 0.2 2 21 813 832 812 833 0.94 17 23 0.00081 0.025 15.5 4.4 1 23 844 866 844 866 0.96 18 23 0.071 2.2 9.4 1.7 2 23 873 895 872 895 0.95 19 23 5.2e-05 0.0016 19.3 2.7 2 23 903 924 902 924 0.96 20 23 0.022 0.66 11.1 8.6 1 23 929 952 929 952 0.93 21 23 0.00032 0.0097 16.8 1.4 3 23 962 982 960 982 0.97 22 23 5.8e-05 0.0018 19.1 0.5 1 23 988 1012 988 1012 0.97 23 23 0.46 14 6.9 1.1 1 23 1018 1041 1018 1041 0.96
Sequence Information
- Coding Sequence
- atgaaacaaaacgCCACTGACTCAGCATTTCTGGTGCAAGAAGGGGCAGAAAACGTTGAACTGCagCCCGACCTCAAGCAGGACTCGGAAGAGGAAGATTTTCTTCCACCGGAACCGGAACCCGCTAAAAAGCACCCCTTCCAGTGCGAAATATGCGACAAAATTCTCTGCAACAAGCAAACCCTCAAATTTCATGCGCTCGTTCACGAAGATCCGACCAAACGGGAAACGTTCCGATGCGAGATCTGCGAGGGCATTTTCAAGTCTCGAGTCGCGTTGAAATATCACCTGAAAACGCAGCACGTCCCGGAAAATGAGCGCAAGAAGCTGCCCTGTCCAACGTGCGGCCGGATTTTCAAAAGCGAGGAAGGCCGGAAGATCCACATGACCATTCAGCATGGAGCCGGGGGACCGATCTTCAAGTGCAAGGAATGTCCGATGGTATTCGCGCGGAAGCCCCACCTAGAACTGCACATGGCAACTCATGGAGCGGGCCAACACGTTTGCATGACCTGCGGGAAGTCGTACGCCAGGCTGAAGGACCTGTCCCGGCACGAGGCCACCTGCGGCGTCAAGGAACTGTGCTGTCCGGTGTGTGGCAAGCAGCTTCGGACGGAGCAAGCGCTTGAGAATCACCGGAAAAAATGCCGATCGAGCGGTTTGAGGTGTGAAGTCGGTGACGGTGAGAGGCGGGAACGTCCGAAAAAGAGCGGCTCCGGCGGCGAGGATGGCAAGGTTCGCATGAGACGCAGCAAACATGACCGGTTTCTTGGACTGGACCATTTGGCGGATCCATCTTCGCTGGTCGAAGCAGTCGTGGAACCGGCCAGGGTTGAGCCAAAGCCGAAGGAACGCATTTTGAAGAGATTCCAGTGCGAGCATTGTCCGCTGAAGCTGGCCGGAAAGATAGCATTGTTGAATCACGGACGCAGACGGCACTGGGAAGCTTTCGGGCTAACGGAGCCGGCTCCCGAAAAGCGAGGACGCAAGCGGACGCATCCGGTGGGACAAAAGAGGAAGAGGATTCGCAATCGGCGTAAGATCATCAACTATGTTGACCCTGAGGAGTTGCCGGAAGAGGATGAGTGTGACGCAGAGAACGAGGAAGCTGATCCTGTGAAGGCGGGAGATGTTGAAATCGGAGAACAGACGATCGAAGATCCAGTTGGGAACGTGACCATTCCAGAAGATATTAAAGAAAACGTTGTGTACATTGAGGAGAAATTGCAGCCAattcaaaatgttgaagaaCCAACACTTGCGGCAAACGAAGGCGCCATCAAGGAAGAGATCATTGAGTTTGGCGAGTacgaatttgaacactttgaggGTGATTCGACCGAGGAGGAGGCCGCCGACGTTGAGGATGAAACGTTTGAGCACGTTGCGGCTGACCTTGGGCCCTTGATTCCGGAAGAGCCGCCCAGCGATGAAGTGGACACTCTCGACGTTGAACCGGCGAATGATCCACAAGTCTGCGACGAACTCGTGATCAAACTGGAAAAGCTAGATTACACCAAGCTGGTTAATTCGGAGGGGAGGCCAACGTACCGTTGTGAAGAGTGCGGTAAATCGTACCAGCTTAAGCATAACCTCAAGGCGCACAACGAAAAAGTGCACGGCATCACGGAAGAACCTGGTGACGGTGCTAATATTCGAACCTGTAAGCACTGCGGACAGAAGTTGAAATCCTGGCAGAGTCTTGTcaaacatttgaagtttttccaCGCAGGAAGTGTCGACGAATCGCAGTTCGTTAAATGTCCGTTGTGTCCTGCGAAGTTTCTCAATCAGGAAGACTTGGACGGGCACGTCTGCACCAAGAGAGACGTTTGCGAAAGGGAACCAAGGGAGCGTTCCTTCAAGTGTGATCTGTGCCGTAAAACGTACTCTTTCCTGCTTCATTTGGAAGCGCACTATTCCGTGCATCCAGAATGTCAGAACTTCAAATGTGACCACTGTTCGAACGGATTCTACAACGAAAGGGAGCTGAACAAGCACAAGAAGAACGTGCACGAACCGGTGGTGAAACCTGCGGTGACGAAGATTCGCCCCTTCAAATCCAAGTACAAAAATCCGTTTCCCAGGACGGAATGCGAACAATGTGGACAAACGTTTGCCTACCGATACCGGCTAGCGCTGCACCGGGTCAAGGAACACGGAAGTACGGAAATTCCAGTGGCAAACAGACCAGTTCCAAAGACGACGTTTCCAAGAAACTTCCCTTGTGACCAGTGCGATAAATCATACCATCTTCAGACTAATCTCACGATTCACAAAGCCAAGGTTCACGGCGTTGGAGAAGCCCCGTCAAAGCATAGGTTAGCCTTTTTGCACACCTGCAAGGTCTGTAAAAAGCAAGTCACAAATTTTGGTGTTCTGGTCTACCATATGAAGTTTAAGCACGGAATAAGCATCGATGAGTCGAAGTTCGTTCAATGCCCGTCGTGTCGAATCAAATTCATCACCGAAAAAGAAATGGCGGAGCATATTTGTCTCAAGGGAGTTGTTCGTGAGAGGAAACATCCCTTCAAGTGCAACTTGTGTGATAAAGCTTATGgcacaaaaaaacatttggaaCACCACTACTCCGCTCATCCGGAATACCACAACGTCAAGTGTGACCAATGTCCTAGAGGGTTCTACAACGACCGGGAACTCAACCTACACAAGAAACACATGCACAAACCAAAAGATGCCTACGTTGAGTGCGAGATCTGCAATAAGCTGTTCAAAAACCAACGAAACTtgaaacaccaccagcagcttcACATGGATCGCGAGTACTGTTGTGAGCATTGTGGTAAAACGTGTAAAACTTTACATTTGCTGCAATCGCACGTACAATTCATTCACTCGAATCCAAACGATCTACTGATCGCTTGCACAATTTgtgggaaaaaaatcaaaggaaaaACAAGCCTAAAACATCACATGAAAATACACAACAACGATCGACCGTTCAAATGTTCCTTTCCGTCCTGTGGCAAAAGCTTCATCACGAGGGGCGATTTGAACAATCACGTGCAAAGTCACACAAAGGATTACAAGTACAAGTGCAAGTTCTGCGATTATGGGACTATTTCACGGAAGACAATTGTGCAGCACGAACAGCGGGAGCATAATCATAACCAGCTCGCTGAAGTGAACGATTCGTAA
- Protein Sequence
- MKQNATDSAFLVQEGAENVELQPDLKQDSEEEDFLPPEPEPAKKHPFQCEICDKILCNKQTLKFHALVHEDPTKRETFRCEICEGIFKSRVALKYHLKTQHVPENERKKLPCPTCGRIFKSEEGRKIHMTIQHGAGGPIFKCKECPMVFARKPHLELHMATHGAGQHVCMTCGKSYARLKDLSRHEATCGVKELCCPVCGKQLRTEQALENHRKKCRSSGLRCEVGDGERRERPKKSGSGGEDGKVRMRRSKHDRFLGLDHLADPSSLVEAVVEPARVEPKPKERILKRFQCEHCPLKLAGKIALLNHGRRRHWEAFGLTEPAPEKRGRKRTHPVGQKRKRIRNRRKIINYVDPEELPEEDECDAENEEADPVKAGDVEIGEQTIEDPVGNVTIPEDIKENVVYIEEKLQPIQNVEEPTLAANEGAIKEEIIEFGEYEFEHFEGDSTEEEAADVEDETFEHVAADLGPLIPEEPPSDEVDTLDVEPANDPQVCDELVIKLEKLDYTKLVNSEGRPTYRCEECGKSYQLKHNLKAHNEKVHGITEEPGDGANIRTCKHCGQKLKSWQSLVKHLKFFHAGSVDESQFVKCPLCPAKFLNQEDLDGHVCTKRDVCEREPRERSFKCDLCRKTYSFLLHLEAHYSVHPECQNFKCDHCSNGFYNERELNKHKKNVHEPVVKPAVTKIRPFKSKYKNPFPRTECEQCGQTFAYRYRLALHRVKEHGSTEIPVANRPVPKTTFPRNFPCDQCDKSYHLQTNLTIHKAKVHGVGEAPSKHRLAFLHTCKVCKKQVTNFGVLVYHMKFKHGISIDESKFVQCPSCRIKFITEKEMAEHICLKGVVRERKHPFKCNLCDKAYGTKKHLEHHYSAHPEYHNVKCDQCPRGFYNDRELNLHKKHMHKPKDAYVECEICNKLFKNQRNLKHHQQLHMDREYCCEHCGKTCKTLHLLQSHVQFIHSNPNDLLIACTICGKKIKGKTSLKHHMKIHNNDRPFKCSFPSCGKSFITRGDLNNHVQSHTKDYKYKCKFCDYGTISRKTIVQHEQREHNHNQLAEVNDS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00401918;
- 90% Identity
- iTF_00401918;
- 80% Identity
- -