Cpip018332.1
Basic Information
- Insect
- Culex pipiens
- Gene Symbol
- -
- Assembly
- GCA_016801865.2
- Location
- NW:14738-18138[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 23 0.0045 0.14 13.2 0.3 1 23 47 69 47 69 0.93 2 23 0.0025 0.077 14.0 1.1 1 23 78 101 78 101 0.98 3 23 0.0042 0.13 13.3 0.1 2 23 111 133 110 133 0.94 4 23 2.1e-05 0.00066 20.5 0.6 1 23 140 162 140 162 0.99 5 23 0.0023 0.07 14.1 0.2 1 20 167 186 167 188 0.92 6 23 0.032 1 10.5 0.3 2 21 195 214 194 215 0.93 7 23 0.12 3.8 8.7 0.4 1 23 290 313 290 313 0.97 8 23 0.00098 0.03 15.3 1.7 1 23 515 538 515 538 0.94 9 23 6.9e-05 0.0021 18.9 2.9 2 23 552 574 552 574 0.95 10 23 6.8 2.1e+02 3.2 0.1 2 21 585 604 584 605 0.91 11 23 0.0045 0.14 13.2 1.1 1 23 619 641 619 641 0.98 12 23 0.014 0.42 11.7 3.3 1 23 647 670 647 670 0.96 13 23 0.0006 0.019 15.9 4.3 2 23 694 716 693 716 0.94 14 23 0.0051 0.16 13.0 2.1 1 23 737 760 737 760 0.95 15 23 1.9 58 4.9 3.0 1 23 777 800 777 800 0.94 16 23 3.4 1e+02 4.1 0.4 2 10 811 819 810 829 0.88 17 23 0.01 0.31 12.1 0.8 1 23 842 864 842 864 0.98 18 23 0.077 2.4 9.3 2.1 2 23 871 893 870 893 0.95 19 23 0.0049 0.15 13.1 0.5 2 23 901 922 900 922 0.96 20 23 0.00023 0.0069 17.3 1.9 1 23 927 950 927 950 0.97 21 23 0.00027 0.0084 17.0 0.7 3 23 960 980 958 980 0.97 22 23 7.7e-05 0.0024 18.8 0.6 1 23 986 1010 986 1010 0.97 23 23 1.1 32 5.7 1.1 1 23 1016 1039 1016 1039 0.94
Sequence Information
- Coding Sequence
- atgaaacaaaacgCCCCTGACTCTCCATTGCTTTTACAAGAAGGGACAGAAAACGTTGAACTGCAGCTCGACTTCAAGCAGGACTCGGAAGAGGAAGATTTTCTTCCACCGGAACCAAAACCCGCTAAAAAGCACCCCTTCCAGTGCGAAATATGCGACAAAATTCTCACGACCAAGCAAAACCTCAAATTCCATGCGATCGTTCACGAAGATCCGACCAAACGGGAAACGTTCCGATGCGAGATCTGCGAGGGCAATTTCAAGTCTCGAGTCGGGTTGAAATATCACCTGAAAACGAAGCACGTCGCGGAGAATGAGCGCGAGAAGCTGCCCTGCCCGACGTGCGGCCGGATTTTCAAAAGCGAGGAAGGCCGGAAGATCCACATGACCATTCAGCATGGAGCCGGGGGACCAATCTTCAAATGCAAGGAATGTCCGATGGTATTCGCGCGGAAGCCCCACCTCGACCTTCACATGGCGACTCATGGCGCGGGCCAGCACGTTTGCATGACCTGCGGGAAGTCGTACGCCAGGCTGAAGGACCTGTCCCGGCACGAGGCCACCTGCGGCGTCAAGGAACTGTGCTGTCCGGTGTGTGGCAAGCAGCTTCGGAGCGAGCCAGCGCTTGAGAATCACCGGAAAAAGTGCCGATCGAGCGGTTTGAGGTGTGAAGTCGGTGACGGTGAGAGGCGGGGACGTCCGAAAAAGAGCGGCTCCGGCGGCGAGGATGGCAAGGTTCGCATGAGGCGCAGCAAACATGACCGGTTTCTTGGACTGGACCATTTAGCGGATCCATCTTCGCTGGTCGAAGCAGTCGTGGAACCGGCCAGGGTTGAGCCAAAGCCGAAGGAACGCATTTTGAAGAGATTCCAGTGCGAGCATTGTCCGCTGAAGTTGGCCGGAAAGATAGCACTGTTGAATCACGGACGCAGACGGCACTGGGAGGCTTTCGGGCTAACGGAGCCGGCTCCCGAAAAGCGAGGACGCAAGCGGACGCATCCGGTGGGACACAAGAGGAAGAGGATTCGCAATCGGCGTAAGATCATCAACTATGTTGACCCTGAGGAGTTGCCGGAAGAGGATGAGTGTGACGCAGAGAACGAGGAAGCTGATCCGGTAAAGGCGGAAGATGTTGAAGTCGGAGAACCGACGATCGAAGATCCAGTTGAGAACGTGACCATTCCAGAAGATATTAAAGAAAACGTTGTGTACATTGAGGAGAAATTGCAGCCAACTCAAAATGTTGAAGAACCAACACTTGCTGCAAACGAAGGCGCCATCAAGGAAGAGATCATTGAGTTTGACGAGTACGAATTCGGTCACTTTGAGGGTGATTCGACCGACGACGATCCCGTTGAGGATGAAACGTTTGAGCACGTTGCGGCTGATCTTGGGCCCTTGATTCCGGAAGAGCCGCCCAGCGATGAAGTGGACACTCTCGACGTTGAACCGGCGAATGATCCACAAGTCTGCGACGAACTCGTGATCAAACTGGAAAAGCTAAATTACACCAAGCTGGTTAATCCGAAGGGGACGCCAACGTACCGTTGTGAAGAGTGCGGTAAATCTTACCGGCTTGAGCATTACCTTAAGGTGCACAACGAAAAAGTTCACGGCATCACGGAAGAAACTGTTGAAGGTGTTTCTTTACGCTCTTGCAAGCACTGTGGAAAGAAGTTGAAATCCTGGTATAATCTACTCAAACACATAAAGTTGTACCACGGTGAAACCTTCGAAGAATCACAGATCGTTAAATGTCCGTCGTGTCCTGTGAAGTTTCTCAATCAAGAAGACTTAGTCGGGCACGTCTGCACTAGGAGTGGCGTTTGCGAAAGGGAACCAAGGGAGCGTTCCTTCAAGTGTGATCTGTGCCGTAAAACGTACACTTTCCTCCTTCAATTGGAAGCGCACTATTCCGTGCATCCAGAATACCAGAACTTCAAATGTGACCACTGTTCGAACGGATTCTACAACGAAAGGGAGCTGAACAAGCACAAGAAGAACGCGCACGAACCGAAACCTGCGGTGACGAAGATTCGCCCCTTCAAATCCAAGTACAAAAATCCGTATCCCCGAAAGGAATGTGAACATTGTGGACAAACGTTTGCACACCAATACCATCTAGCCCAGCACCGAGTCAAGGAACATGGAAGCACGGAAACACCGGTGGCAAACAAATTAGTTCCAAAGACTACGCTTCCACGAAACTTCTCTTGTGACCAGTGCGATAAATCATACCATCTTCAGACTAATCTCACGATTCACAAGGCCAAGGTTCATGGCGTTGGAGAAGCCCCACCAAAGTATCAACCAACCAAAATCTTAAAGCATACCTGCAAACACTGTAAAAAGGAAGTGTTAACCTGGCGCGGTCTAGTCTACCATCTGAAGAACATCCACGGAGAAACCATCGACGAAACGCAGCTTGTCAAATGTCCGTTGTGTCATAAGAAATTCCTCACCGATGAGGAAATGACTGGACATTTTTGCTTCAGAAGAAACGTTCCCGAAAAGGATCGTCCCTTTAAGTGTGACCTGTGCGAAAAAGCTTACCCCCTGAAAAATCATCTGGAAGGCCACTATTCCGTCCATCCGGAATACCACAACGTCAAGTGTGACCAATGTCCGAGGGGATTCTACAACGAACGGGAATTCAACCTACACAAGAAACACATGCACAAACCAAAAGATGCCTACGTTGAGTGCAAGATCTGCAATCAGTTGTTCAAAAGCACACAATACTTGGCACGACACCAGGAACTTCACTCCGATCGTAAATACTTTTGTGAACATTGTGGCAAACCGTTTAAATCTCGATTTATGATACAATGGCACGTAAAAACCATTCACACGAATCCAAACGATCAACTGATCGCTTGCACAATTTgcgggaaaaaaatcaaaggaaaaACAAGCCTGAAATATCACATGAAAACACACAACAACGATCGACCGTACACATGTTCCTTTCCGTCCTGTGACAAAAGCTTCATCACGAGGGGCGATTTGAACAAGCACGTGCAAAGTCACACAAAGGATTATAAGTACAAGTGCAAGTTCTGCGATTATGGGACTATTTCACGGAAGACAATTGTGCTGCACGAGCAGCGGAACCATAACCACAACCGGTTCGCTGAAGTGAACGATTCGTAA
- Protein Sequence
- MKQNAPDSPLLLQEGTENVELQLDFKQDSEEEDFLPPEPKPAKKHPFQCEICDKILTTKQNLKFHAIVHEDPTKRETFRCEICEGNFKSRVGLKYHLKTKHVAENEREKLPCPTCGRIFKSEEGRKIHMTIQHGAGGPIFKCKECPMVFARKPHLDLHMATHGAGQHVCMTCGKSYARLKDLSRHEATCGVKELCCPVCGKQLRSEPALENHRKKCRSSGLRCEVGDGERRGRPKKSGSGGEDGKVRMRRSKHDRFLGLDHLADPSSLVEAVVEPARVEPKPKERILKRFQCEHCPLKLAGKIALLNHGRRRHWEAFGLTEPAPEKRGRKRTHPVGHKRKRIRNRRKIINYVDPEELPEEDECDAENEEADPVKAEDVEVGEPTIEDPVENVTIPEDIKENVVYIEEKLQPTQNVEEPTLAANEGAIKEEIIEFDEYEFGHFEGDSTDDDPVEDETFEHVAADLGPLIPEEPPSDEVDTLDVEPANDPQVCDELVIKLEKLNYTKLVNPKGTPTYRCEECGKSYRLEHYLKVHNEKVHGITEETVEGVSLRSCKHCGKKLKSWYNLLKHIKLYHGETFEESQIVKCPSCPVKFLNQEDLVGHVCTRSGVCEREPRERSFKCDLCRKTYTFLLQLEAHYSVHPEYQNFKCDHCSNGFYNERELNKHKKNAHEPKPAVTKIRPFKSKYKNPYPRKECEHCGQTFAHQYHLAQHRVKEHGSTETPVANKLVPKTTLPRNFSCDQCDKSYHLQTNLTIHKAKVHGVGEAPPKYQPTKILKHTCKHCKKEVLTWRGLVYHLKNIHGETIDETQLVKCPLCHKKFLTDEEMTGHFCFRRNVPEKDRPFKCDLCEKAYPLKNHLEGHYSVHPEYHNVKCDQCPRGFYNEREFNLHKKHMHKPKDAYVECKICNQLFKSTQYLARHQELHSDRKYFCEHCGKPFKSRFMIQWHVKTIHTNPNDQLIACTICGKKIKGKTSLKYHMKTHNNDRPYTCSFPSCDKSFITRGDLNKHVQSHTKDYKYKCKFCDYGTISRKTIVLHEQRNHNHNRFAEVNDS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00401918;
- 90% Identity
- -
- 80% Identity
- -