Cqui014283.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Culex quinquefasciatus
Gene Symbol
ftz-f1
Assembly
GCA_015732765.1
Location
NC:186405862-186677769[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 4 0.13 9.3e+02 -1.3 5.2 50 183 41 176 3 204 0.57
2 4 5.8e-17 4.3e-13 49.2 4.4 1 36 297 331 297 347 0.82
3 4 0.35 2.6e+03 -2.8 0.1 112 156 374 413 351 425 0.53
4 4 1.2e-76 8.6e-73 245.8 0.0 117 408 468 760 454 761 0.91

Sequence Information

Coding Sequence
ATGCACGAAGAAGCGTCCTCAACTGCGGCCAGTTCCTCCACGGCaccgtcatcatcgtcgtcctCGTCCAAGAACATCATCTACGGTTCCGCTCCCTTCCACGGCAATCTCCTAATCACCACCTCCCAACTTCCCGACCCCAACTCCTCGTCCCTGTACGAGCTGATCCACCAACCGGCCGCCCCCATGAACCACCATCACAACCTGCACCACCACAATCCCATGACCTCCAAGCTCGTCCTGTCCAACAACTCCCTCATCTCCACCACGACCGCCCCGAACCCACTCGTCGAAGACGAGTTCAACGTCGTGGCCAGTTCCGCCGACCTGCACGAACTGGCGGCCGCCGCCAATCTGGACGACTCCACCAGCGATGCGGTGGCGGCCGCGGCCGCCCTCATCGACCTgcatccgtcgtcgtcgtcctcgtcggCGGCGGTGATTCCGGAGCTGGCCACGGCCACCAGCAGCTCGGGCAGTGGGTGCAGTTCGCTGGAGGAAGCGGTCGGACCGCTCGAACCTATTGAGATCAAGATTCCGGGTTCGGGGGTGGCGGCGGCTGCAGCGACCTCCGCCGACGATGGGTCCTCGTATGCGGAAGGGTCGTCCGATGGTGGCTACCACGAGAACATCTCCCAGACGCAGTCCAACTATCTAGCGGCGATCCCCCCGTCAGaACTGTGCCCCGTGTGCGGTGACAAAGTTTCAGGCTACCACTACGGACTGCTGACGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGTACCGTCCAGAACAAGAAGGTGTACACGTGCGTCGCCGAGCGGCAGTGCCACATCGACAAGACGCAGCGCAAGCGGTGCCCGTACTGCCGCTTCCAGAAGTGTCTCGAGGTCGGCATGAAGCTAGAAGCGGTCCGCGCCGACCGGATGCGCGGCGGCCGGAACAAGTTCGGCCCCATGTACAAGCGCGACCGGGCGCGGAAGCTTCAAATCATGCGCCAGCGGCAGCTCGCCATCCAGGCACTTCGGGGGTCGATAGGTGGCGGCGTCGGCATCGGCCAGCTCGGCACGGCAGCAGACGGATCGtcaccggcggcggcggcggcagcggcCGCGGCAGGTCTCCAGGGTCTCGACTACCACCAGTCGCCGTACTCGAGTATGCACATCAAGCAGGAAATCCAAATACCGCAGGTGTCCTCGTTGACGTCCTCGCCGGACAGTTCGCCGAGTCCGATCGCGATCGCGCTTGGCCAGGTCAACCCGCAGACGACGATCTCGTTGAGCAGTGGCGTCGGTGGCAACGGGAGCAGCGGCGGAGGTGGCAGCAGTGGCGGCGTCGGCGGTGGAGGAGGAACGGGCGGCGGTGCGGGCAATGGTGGGGCAGGTTCCGGCGGTGCGGGCACCAACGGCGGCTCCAACTCGACGTCCGCCGCCATCCAGAGCCAACTGTCCGAGTCGAAGCTATGGATGAGCGCCAACTCGACGACCGCCTCACCACACTCGCTAAGTCCCAAAACGTTCAGCTTCGACAGCGGCACCAACCCCACCAGCACCGCCGACAACCCAGCGGACACGTTAAGGGTCTCGCCGATGATACGCGACTTTGTGCAGTCCATCGACGGGGACGACCGGGAGTGGACGGCGTCCCTGTTTTCGCTGTTGCAGAACCAGTCGTACAACCAGTGCGAGGTCGACCTGTTCGAGCTGATGTGCAAGGTGCTGGACCAGAATCTGTTCTCGCAGGTCGACTGGGCGCGGAACACGATATTCTTCAAGGATTTGAAGGTGGACGACCAGATGAAGCTGCTGCAGAACAGCTGGTCGGACATGCTGGTGCTCGACCACATCCACCAGCGGTTGCACAACGCGCTGCCGGACGACACGACGCTCCACAACGGGCAAAAGTTTGATCTCTTAGGGTTAGGGCTGCTGGGCGTCCCGAGCTTGGCCGAGCACTTCAACGAGCTGCAGAACAAGCTGCAGGAGCTCAAGTTCGACGTCGGCGACTACATCTGCATGAAGTTCCTGCTGCTGCTCAACCCCGGCAAGGGTGcagATGTTCGGGGGATCACCAACCGAAAGACGGTCATCGAAGGCTATGAAAACGTGCAAGCGGCGCTGCTGGATTACACCCTCACCTGTTATCCGTCGGTGCCCGACAAGTTCGCCAAGTTGCTCAGTATTATTCCGGAGATTCACGTGATCGCGTCCCGGGGCGAGGAGCACCTGTACATCAAGCACTGCGCCGGCAGCGCCCCCAGCCAGACGCTGCTGATGGAGATGCTGCACGCCAAGCGGAAATGA
Protein Sequence
MHEEASSTAASSSTAPSSSSSSSKNIIYGSAPFHGNLLITTSQLPDPNSSSLYELIHQPAAPMNHHHNLHHHNPMTSKLVLSNNSLISTTTAPNPLVEDEFNVVASSADLHELAAAANLDDSTSDAVAAAAALIDLHPSSSSSSAAVIPELATATSSSGSGCSSLEEAVGPLEPIEIKIPGSGVAAAAATSADDGSSYAEGSSDGGYHENISQTQSNYLAAIPPSELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERQCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQIMRQRQLAIQALRGSIGGGVGIGQLGTAADGSSPAAAAAAAAAGLQGLDYHQSPYSSMHIKQEIQIPQVSSLTSSPDSSPSPIAIALGQVNPQTTISLSSGVGGNGSSGGGGSSGGVGGGGGTGGGAGNGGAGSGGAGTNGGSNSTSAAIQSQLSESKLWMSANSTTASPHSLSPKTFSFDSGTNPTSTADNPADTLRVSPMIRDFVQSIDGDDREWTASLFSLLQNQSYNQCEVDLFELMCKVLDQNLFSQVDWARNTIFFKDLKVDDQMKLLQNSWSDMLVLDHIHQRLHNALPDDTTLHNGQKFDLLGLGLLGVPSLAEHFNELQNKLQELKFDVGDYICMKFLLLLNPGKGADVRGITNRKTVIEGYENVQAALLDYTLTCYPSVPDKFAKLLSIIPEIHVIASRGEEHLYIKHCAGSAPSQTLLMEMLHAKRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00400678; iTF_00401809; iTF_00400604;
90% Identity
iTF_00400604;
80% Identity
iTF_00401809;