Basic Information

Insect: Culex pipiens
Gene Symbol: ftz-f1
Assembly: GCA_016801865.2
Location: NC:15175051-15452952[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.22 5.7e+02 0.2 4.7 77 160 7 90 1 165 0.78

2 4 1.8e-15 4.7e-12 46.6 7.5 1 40 294 332 294 401 0.82

3 4 1.9 4.8e+03 -2.9 0.1 114 153 372 407 348 421 0.53

4 4 6.5e-76 1.7e-72 245.6 0.0 118 408 466 757 451 758 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.22	5.7e+02	0.2	4.7	77	160	7	90	1	165	0.78
2	4	1.8e-15	4.7e-12	46.6	7.5	1	40	294	332	294	401	0.82
3	4	1.9	4.8e+03	-2.9	0.1	114	153	372	407	348	421	0.53
4	4	6.5e-76	1.7e-72	245.6	0.0	118	408	466	757	451	758	0.91

Sequence Information

Coding Sequence: ATGCACGAAGAAGCGTCCTCAACTGCGGCCAGTTCCTCCACGACACCGTCATCGTCCTCGTCCAAGAACATCATCTACGGCTCCGCTCCCTTCCACGGCAATCTCCTAATCACCACCTCCCAACTTCCCGACCCCAACTCCTCGTCCCTGTACGAGCTGATCCACCAACCAGCCGCCCCCATGAACCACCATCACAACCTCCACCACCACAACCCAATGACGACCTCCAAGCTCATCCTGTCCAACAACTCCCTCATTTCCACCACGACCGCCCCGAACCCGCTCGTCGAAGACGAGTTCAACGTCGTGGCCAGTTCCGCCGACCTGCACGAGCTGGCGGCCGCCGCCAATCTGGACGACTCTACCAGCGATGCGGTGGCGGCCGCGGCCGCCCTCATCGACCTGCATCCGTCGTCCTCGTCGGCGGCGGCGGTGATTCCGGAGCTGGCCACGGCCACCAGCAGCTCCGGCAGTGGGTGCAGTTCGCTGGAGGAAGCGGTCGGGCCGCTCGAGCCGATTGAGATTAAGATTCCGGGTTCCGGAGCGGTGGCGGCAGCGACCTCCGCGGACGATGGGTCCTCGTATGCGGAAGGGTCGTCCGATGGTGGCTACCACGAGAACATCTCCCAGACGCAGTCCAACTATCTAGCGGCGATCCCCCCGTCAGaaCTGTGCCCCGTGTGCGGTGACAAAGTTTCAGGCTACCACTACGGACTGCTGACGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGTACCGTCCAGAACAAGAAGGTGTACACGTGCGTCGCCGAGCGGCAGTGCCACATCGACAAGACGCAGCGCAAGCGGTGCCCGTACTGCCGCTTCCAGAAGTGTCTCGAGGTCGGCATGAAGCTAGAAGCGGTCCGCGCCGACCGGATGCGCGGCGGCCGGAACAAGTTCGGCCCCATGTACAAGCGCGACCGGGCGCGGAAGCTTCAAATCATGCGCCAGCGGCAGCTCGCCATCCAGGCACTTCGGGGGTCGATAGGCGGCGGCGTCGGCATCGGCCAGCTCGGCACGGCAGCGGACGGATCGtcaccggcggcggcggcggcagcggcCGCGGCAGGTCTCCAGGGTCTCGACTACCACCAGTCGCCGTACTCGAGTATGCACATCAAGCAGGAAATCCAAATACCGCAGGTGTCCTCGTTGACGTCATCGCCGGACAGTTCGCCGAGTCCGATTGCGATCGCGCTTGGCCAGGTCAACCCGCAGACGACGATCTCGTTGAGCAGTGGCGTCGGTGGCAACGGAAGCAGCGGCGGAGGTGGCAGCAGTGGCGGCGTCGGCGGCGGAGGAGGAACGGGCGGCGGTGCGGGCAATGGTGGGGCAGGTTCCGGCGGTGCGGGCACCAACGGCGGCTCCAACTCGACGTCCACCGCCATCCAGAGCCAACTGTCCGAGTCGAAGCTATGGATGAGCGCCAACTCGACGACCGCCTCACCACACTCGCTAAGTCCCAAAACGTTCAGCTTCGACAGCGGCACCAACCCCACCAGCACCGCCGACAACCCAGCGGACACGTTAAGGGTCTCGCCGATGATACGCGACTTTGTGCAGTCCATCGACGGGGACGACCGGGAGTGGACGGCGTCCCTGTTTTCGCTGCTGCAGAACCAGTCGTACAACCAGTGCGAGGTCGACCTGTTCGAGCTGATGTGCAAGGTGCTGGACCAGAATCTGTTCTCGCAGGTCGACTGGGCGCGGAACACGATATTCTTCAAGGATTTGAAGGTGGACGACCAGATGAAGCTGCTGCAGAACAGCTGGTCGGACATGCTGGTGCTCGACCACATCCACCAGCGGTTGCACAACGCGCTGCCGGACGACACGACGCTCCACAACGGGCAAAAGTTTGATCTCTTAGGGTTAGGGCTGCTGGGCGTCCCGAGCTTGGCCGAGCACTTCAACGAGCTGCAGAACAAGCTGCAGGAGCTCAAGTTCGACGTCGGCGACTACATCTGCATGAAGTTCCTGCTGCTGCTCAACCCCGGCAAGGGTGcGGATGTTCGGGGGATCACCAACCGAAAGACGGTCATCGAAGGCTATGAAAACGTGCAAGCGGCGCTGCTGGATTACACCCTCACCTGTTATCCGTCGGTGCCCGACAAGTTCGCCAAGTTGCTCAGTATTATTCCGGAGATCCACGTGATCGCGTCCCGGGGCGAGGAGCACCTGTACATCAAGCACTGCGCCGGCAGCGCCCCCAGCCAGACGCTGCTGATGGAGATGCTGCACGCCAAGCGGAAATGA
Protein Sequence: MHEEASSTAASSSTTPSSSSSKNIIYGSAPFHGNLLITTSQLPDPNSSSLYELIHQPAAPMNHHHNLHHHNPMTTSKLILSNNSLISTTTAPNPLVEDEFNVVASSADLHELAAAANLDDSTSDAVAAAAALIDLHPSSSSAAAVIPELATATSSSGSGCSSLEEAVGPLEPIEIKIPGSGAVAAATSADDGSSYAEGSSDGGYHENISQTQSNYLAAIPPSELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERQCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQIMRQRQLAIQALRGSIGGGVGIGQLGTAADGSSPAAAAAAAAAGLQGLDYHQSPYSSMHIKQEIQIPQVSSLTSSPDSSPSPIAIALGQVNPQTTISLSSGVGGNGSSGGGGSSGGVGGGGGTGGGAGNGGAGSGGAGTNGGSNSTSTAIQSQLSESKLWMSANSTTASPHSLSPKTFSFDSGTNPTSTADNPADTLRVSPMIRDFVQSIDGDDREWTASLFSLLQNQSYNQCEVDLFELMCKVLDQNLFSQVDWARNTIFFKDLKVDDQMKLLQNSWSDMLVLDHIHQRLHNALPDDTTLHNGQKFDLLGLGLLGVPSLAEHFNELQNKLQELKFDVGDYICMKFLLLLNPGKGADVRGITNRKTVIEGYENVQAALLDYTLTCYPSVPDKFAKLLSIIPEIHVIASRGEEHLYIKHCAGSAPSQTLLMEMLHAKRK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401742;
90% Identity: iTF_00400678; iTF_00401809; iTF_00401742;
80% Identity: iTF_00400678;