Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:137711227-137714082[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.032 0.97 10.5 0.2 3 23 196 217 194 217 0.90

2 16 0.001 0.032 15.2 4.0 1 23 220 242 220 242 0.97

3 16 0.0095 0.29 12.2 0.2 1 23 258 281 258 281 0.91

4 16 0.0033 0.1 13.6 0.6 1 23 291 313 291 313 0.98

5 16 3.8 1.2e+02 4.0 0.3 6 20 321 335 319 337 0.91

6 16 0.0017 0.052 14.5 0.7 2 23 347 369 347 369 0.94

7 16 0.11 3.2 8.9 0.0 2 21 374 393 373 394 0.94

8 16 0.41 12 7.0 0.2 2 23 411 433 411 433 0.95

9 16 0.0075 0.23 12.5 0.6 2 23 439 460 438 460 0.96

10 16 1.3e-05 0.0004 21.2 0.4 1 23 465 487 465 487 0.99

11 16 1.5e-05 0.00045 21.0 2.6 2 23 492 513 491 513 0.97

12 16 0.0029 0.09 13.8 0.0 1 23 519 541 519 541 0.97

13 16 0.0001 0.0032 18.3 2.1 1 23 547 570 547 570 0.97

14 16 0.0001 0.0032 18.3 2.2 1 23 576 598 576 598 0.98

15 16 0.0047 0.15 13.1 0.0 1 23 604 627 604 627 0.96

16 16 0.0024 0.075 14.0 0.3 1 23 633 655 633 655 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.032	0.97	10.5	0.2	3	23	196	217	194	217	0.90
2	16	0.001	0.032	15.2	4.0	1	23	220	242	220	242	0.97
3	16	0.0095	0.29	12.2	0.2	1	23	258	281	258	281	0.91
4	16	0.0033	0.1	13.6	0.6	1	23	291	313	291	313	0.98
5	16	3.8	1.2e+02	4.0	0.3	6	20	321	335	319	337	0.91
6	16	0.0017	0.052	14.5	0.7	2	23	347	369	347	369	0.94
7	16	0.11	3.2	8.9	0.0	2	21	374	393	373	394	0.94
8	16	0.41	12	7.0	0.2	2	23	411	433	411	433	0.95
9	16	0.0075	0.23	12.5	0.6	2	23	439	460	438	460	0.96
10	16	1.3e-05	0.0004	21.2	0.4	1	23	465	487	465	487	0.99
11	16	1.5e-05	0.00045	21.0	2.6	2	23	492	513	491	513	0.97
12	16	0.0029	0.09	13.8	0.0	1	23	519	541	519	541	0.97
13	16	0.0001	0.0032	18.3	2.1	1	23	547	570	547	570	0.97
14	16	0.0001	0.0032	18.3	2.2	1	23	576	598	576	598	0.98
15	16	0.0047	0.15	13.1	0.0	1	23	604	627	604	627	0.96
16	16	0.0024	0.075	14.0	0.3	1	23	633	655	633	655	0.96

Sequence Information

Coding Sequence: ATGCAGTTCGACCTGGTCCGGGACACCACCAAGCTATGTCGGGTGTGCTTGATGGATAGCGATGGACATCGCACCGACCTGTACGAAGTATCCGACCAGCTTAGCTTGCACGAAATGCTGAAAGCCATCTGCGCCACCGTATTTGATAAATCCGATGCTGAGTATCCACCCGGGATGCCTACGACGGTTTGCGCCGACTGCCGGAATGCTGTTCTCGCGGCTTTCAAGCTGCACCAGACGTGCATCGATAATGAGCGTCGGCTGGTGGAGCTGCTGGCGCTAAAGTGGGAGCTTCAAGATCTGGAGATCGAAGAGGAATTCGGAGATCCACTGAAATCCACCAACAAAGAATTGTTGAGCGTTGAAGTGGAAAATCATGCTAAGACCGAAGGAGAAACGCATCTTCTCGAGGAGGAGCAACCAAAAGACGAGATGGAAGATTCACTTTCTGCTGGTGAACATGGAAATACGATAAAGGTTGAAGAATTAGATTTGATGGACGTAGACGACAACGAAAACGGTGATATTCCTGAAACTGGTGAGATCGTGGAACGTTCCTCCGGAGAAGATACGAACAAGACCACCTGTATCATCTGCTCGAAATCGTTTGGTAATGTTGTCATGCTGAGAAAACACATGGCCCTGGAGCATCAGTTGCACATGTGCGAGTTTTGTCCGAAATCTTTCAGAATTCGCGCAAGTTTTACTCGTCATCGGAGGCAACACTTGAAGAAGCATCCGGAGAGAGGCTCGAGCGGATCGCGGAAGGTGTATTCTTGTCAATATTGCGAAGAAACGTTCAAAGTGGGCATGCAACTTATGAGACACAAAGCAGCTGTCCATCGAAATGTAAAAGATCCGAATCAACCTTTTACGTGCAGATTATGCGCGGAATCGTACGCAACAGCAACGGAGCTGATGACCCACAAAAAAACGCATGAAAACCCAGTTAACTGTTCATGTGGACGTAGATTTAAAAATGACATGAGATTACAAGCTCATACCGCGTCCGGAACATGCTCAGGAGATAACGATAGAAGGTGTAACATATGTAATAAAGTCTTCAAATCAGTCGACTTCATGCTTAGACATCGCAACGCGGTGCATTCCGAGTCCGTCGTATGTCCCGAGTGTGGTCAGACGATGGCTAACCTTGCCAGCATGAAAGTGCATTTGCGGATTGGATACTGTTCCGCGCAACCTCCGACGAAGTCTGTGATAGCTGCCAGAACCTGTAAGATTTGTGGCGAAGAACAGAAAAACCGCTACGCTGTAAAAGGTCACATGATACGAGCACATCCGGACCGTATGCTTCGCTGTGGTATGTGCAGTATGGAATTTAGAACTCAAAGATATCTTGATTTGCACATACAATACCACGAAACCAAAACGttcaaatgtaaaatttgtgACGAAACCGTGAACTCAAAAGATGCTCTTGTAAAGCACCGACGAATCCACAGAGACCCCATCACGTGCTCagtttgtgacaaaaagttcgCATCCAAACATACTCTTACTACCCACATGGAGCGACACATAGGCATCAAACCGTTCGCCTGTGACGTTTGTCCGATGCGGTTTATTACGAAAGTAGAGATCCAAGGTCACATGGCAACGCACACCAAGCAACAGGACCATGTTTGTGATCTTTGCGGATCTcggttcacaaaaaaatattcgttgAAAGTACATATCAAGCGAGTTCACGAGGGTGTTCGGCCCTTCTCGTGTTCGCAGTGCAGTTTAAAGTTTACCACAGCGGATCGACTACAGCGCCACATGTACACCCATACAGGGGAAAAACCGTACACGTGTGAACTTTGCCCGCAGGCTTACGCCCAGACCAACGATCTGGTCAAGCACGTGGCCCGCGCCCACGGCGATGGCAATCCGTACCTTTGCGACCTGTGCGACGAGGGGTTCAAGCTTATGACGGACCTGCGCCAGCACTATCGGGTGCACGTGCAATCGACTGAAGGTGGCACCGAAAAGATGGAGGAGGTACGCTTCACCAGTGTAGCGATACTGAAGCGGGTTTTCGCTAAAGCTAAACAACGGATGTGA
Protein Sequence: MQFDLVRDTTKLCRVCLMDSDGHRTDLYEVSDQLSLHEMLKAICATVFDKSDAEYPPGMPTTVCADCRNAVLAAFKLHQTCIDNERRLVELLALKWELQDLEIEEEFGDPLKSTNKELLSVEVENHAKTEGETHLLEEEQPKDEMEDSLSAGEHGNTIKVEELDLMDVDDNENGDIPETGEIVERSSGEDTNKTTCIICSKSFGNVVMLRKHMALEHQLHMCEFCPKSFRIRASFTRHRRQHLKKHPERGSSGSRKVYSCQYCEETFKVGMQLMRHKAAVHRNVKDPNQPFTCRLCAESYATATELMTHKKTHENPVNCSCGRRFKNDMRLQAHTASGTCSGDNDRRCNICNKVFKSVDFMLRHRNAVHSESVVCPECGQTMANLASMKVHLRIGYCSAQPPTKSVIAARTCKICGEEQKNRYAVKGHMIRAHPDRMLRCGMCSMEFRTQRYLDLHIQYHETKTFKCKICDETVNSKDALVKHRRIHRDPITCSVCDKKFASKHTLTTHMERHIGIKPFACDVCPMRFITKVEIQGHMATHTKQQDHVCDLCGSRFTKKYSLKVHIKRVHEGVRPFSCSQCSLKFTTADRLQRHMYTHTGEKPYTCELCPQAYAQTNDLVKHVARAHGDGNPYLCDLCDEGFKLMTDLRQHYRVHVQSTEGGTEKMEEVRFTSVAILKRVFAKAKQRM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400824; iTF_00401929;
90% Identity: -
80% Identity: -