Cpra009341.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cryptocheilus praepositus
Gene Symbol
HMG20A
Assembly
GCA_033815515.1
Location
JAWWQZ010000204.1:578638-579571[+]

Transcription Factor Domain

TF Family
HMG
Domain
HMG_box domain
PFAM
PF00505
TF Group
Other Alpha-Helix Group
Description
High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 7.3e-18 6.1e-15 55.9 2.4 1 69 122 193 122 193 0.93

Sequence Information

Coding Sequence
atGTCAGATGAATCGGAATACGACGTAGAACCGGAGGAATTTGACATCTACAAAAGGAAATATCAACTGTTACTGGACAGATGTGAAATTTTGCAGCAGGAAAACGAGAGACTAGTATACCGTATCCAAAGGGTCAGGAAGCTTCTCAAACGCACGAGGAAGGAGAAAAAGTTTTTAATAGACAGATTAGATCAGCACGGTGATCGTTGGCGTGAGGCACCGATGGGTGTGCTGGAAGAAAACAGCGTCTTTCAAGCTACTCCTAAGCAGGAAAAGGGATCGAAAGCAGCAGCGCACAATTCCAAAGAAGAGAAACCAAAAAAAGGCACAAAGAGGAAAGGCACAAAAGCAGACCCCAATGCTCCGAAAAGGCCTGCCAATCCATTCTTCCAGTTTTGCCAAGAACAGAGACCTCGCGTAATGGAGCGGCTGGCTGGTGAGCCGGAACCGAGCAAGCAGGAACTTACAAGGCAACTTGCAACAACATGGAAGTCCCTCAGTTCTGAGGACAAAAAAGTGTACTATGATATGTATGAGCGCTCCAAAGAGAAGTACGTGGCTGAAATGcagatttataataaaaaaactgaaGACGCGCCCAATCAAATGTCTCTAAATATAGCATAG
Protein Sequence
MSDESEYDVEPEEFDIYKRKYQLLLDRCEILQQENERLVYRIQRVRKLLKRTRKEKKFLIDRLDQHGDRWREAPMGVLEENSVFQATPKQEKGSKAAAHNSKEEKPKKGTKRKGTKADPNAPKRPANPFFQFCQEQRPRVMERLAGEPEPSKQELTRQLATTWKSLSSEDKKVYYDMYERSKEKYVAEMQIYNKKTEDAPNQMSLNIA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01122412;
90% Identity
iTF_01255528; iTF_00293698; iTF_01475428; iTF_00253543; iTF_01473159; iTF_01474664; iTF_01130793; iTF_01473900; iTF_00298287; iTF_00252048; iTF_00770352; iTF_00294452; iTF_00296756; iTF_01198646; iTF_00292248; iTF_00295224; iTF_00295992; iTF_01199385; iTF_00291514; iTF_00297530; iTF_00292923; iTF_00773788; iTF_01395102; iTF_00306242; iTF_00625475; iTF_00754628; iTF_00964455; iTF_00961802; iTF_00962488; iTF_00963167; iTF_00963831; iTF_01070343; iTF_00117988; iTF_01067590; iTF_01266856; iTF_01269774; iTF_01270479; iTF_01267540; iTF_01271189; iTF_01268247; iTF_01269024; iTF_00230668; iTF_00221889; iTF_00982946; iTF_01419618; iTF_00214371; iTF_00225891; iTF_00087140; iTF_00228644; iTF_00760964; iTF_00763204; iTF_00983588; iTF_01424356; iTF_00215686; iTF_00222502; iTF_00227942; iTF_00864614; iTF_00087975; iTF_00232583; iTF_01066919; iTF_00633608; iTF_00085353; iTF_00862537; iTF_00860362; iTF_00862538; iTF_00865290; iTF_01065547; iTF_00223852; iTF_00141805; iTF_00142445; iTF_00220557; iTF_00226573; iTF_00733934; iTF_00863246; iTF_01069646; iTF_01420911; iTF_00219088; iTF_00084529; iTF_00086257; iTF_00140561; iTF_00216369; iTF_00224529; iTF_00229329; iTF_01417681; iTF_00684146; iTF_00360883; iTF_01068276; iTF_00024597; iTF_00214997; iTF_00230006; iTF_00233206; iTF_00227255; iTF_00141208; iTF_00221240; iTF_00863928; iTF_00866680; iTF_01418328; iTF_00217049; iTF_00231961; iTF_00861113; iTF_01068953; iTF_01169145; iTF_00218394; iTF_00861850; iTF_01066234; iTF_01071003; iTF_00982268; iTF_00762525; iTF_00865981; iTF_01418973; iTF_00675998; iTF_01420254; iTF_00088799; iTF_00217727; iTF_00223167; iTF_00225215; iTF_00360191; iTF_01539583; iTF_00219776; iTF_00231296; iTF_00303008; iTF_00684768; iTF_01454065; iTF_01232978; iTF_01233633; iTF_01234324; iTF_01235005; iTF_01232383; iTF_01513451; iTF_01512162; iTF_01512811; iTF_01514131; iTF_01514803; iTF_01089976; iTF_01498201; iTF_00391270; iTF_00252795; iTF_00255059; iTF_01120188; iTF_00254301; iTF_00183262; iTF_00183921; iTF_01123040; iTF_01122412;
80% Identity
iTF_01255528;