Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.37 6.9e+02 0.8 0.0 16 45 91 120 82 125 0.78

2 6 0.00034 0.62 10.5 0.0 22 52 153 183 147 184 0.87

3 6 0.19 3.6e+02 1.7 0.0 23 43 182 202 178 206 0.88

4 6 0.025 46 4.5 0.1 22 46 209 233 204 239 0.89

5 6 0.0038 7.1 7.1 0.0 22 52 237 267 232 268 0.88

6 6 0.032 59 4.2 0.0 22 47 265 290 262 296 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.37	6.9e+02	0.8	0.0	16	45	91	120	82	125	0.78
2	6	0.00034	0.62	10.5	0.0	22	52	153	183	147	184	0.87
3	6	0.19	3.6e+02	1.7	0.0	23	43	182	202	178	206	0.88
4	6	0.025	46	4.5	0.1	22	46	209	233	204	239	0.89
5	6	0.0038	7.1	7.1	0.0	22	52	237	267	232	268	0.88
6	6	0.032	59	4.2	0.0	22	47	265	290	262	296	0.86

Coding Sequence: ATGAGCGACACCTGCGATTGGTGCTCGCGGGGGGCACCAGTGAAAACGATCGACGAGAGGTTGTGGCGCTTTTGGGGAGTGATCAGCGGCGAAAGACCGCTCGACGAATCCTTGAGGAAGATCTGCGGGGAGTGTACGTCGCGCCACGAGGACTTCTCGACGTTCATCGACAGGTGCAAGAGCAACGAGTCGCTCGTGGAGAACTTTCTCGCCCCCTTCGACATCGAGTACCATCCCTTGATCAAATCGGAGCGTCCGACAGACGAGAGTACCGCAGCGTCCGTATCGAACGTCGcattcaagtgctcgctttgcgtcgagaccttcgccgatctcgccgtcctgaagcgccacctacgagcccacacgatcgatgaggccccgaggtgccggctctgcgacaagacgttccgtcggtactattacctcgagagccacatgcgaatccacaccggcgacaggccgttcaagtgtccccactgcgacaagactttcacgcagtccggtaacatgaagagccacttacgtgtccacacgggcggtaagccgttcaagtgtccgaagtgcgataagacattcgctcggtatggcaacctgagggaccactcgatcgtccacacgggcgaagcgccgtacaggtgttctcagtgcgacaagacgttcgcccagtcgagtaagttgaagagccatctgcgcgtccacacgggcgacaggccgttcgagtgtccgcactgtgacaagaagttcacgcagcacggcaacctgaagagccacgttcgcctccacacgggcgacaagccgttcaagtgtccgaagtgtgataagggcttcgcccaatcgagtccgttgaagggccacatgcacgtccacggcgtcgtggaacctttcgagtgtaccgtctgcgGATTCCTATCCTCGTAG
Protein Sequence: MSDTCDWCSRGAPVKTIDERLWRFWGVISGERPLDESLRKICGECTSRHEDFSTFIDRCKSNESLVENFLAPFDIEYHPLIKSERPTDESTAASVSNVAFKCSLCVETFADLAVLKRHLRAHTIDEAPRCRLCDKTFRRYYYLESHMRIHTGDRPFKCPHCDKTFTQSGNMKSHLRVHTGGKPFKCPKCDKTFARYGNLRDHSIVHTGEAPYRCSQCDKTFAQSSKLKSHLRVHTGDRPFECPHCDKKFTQHGNLKSHVRLHTGDKPFKCPKCDKGFAQSSPLKGHMHVHGVVEPFECTVCGFLSS

Sequence clustering based on sequence similarity using MMseqs2