Basic Information

Insect: Cosmia trapezina
Gene Symbol: -
Assembly: GCA_905163495.1
Location: LR991040.1:18095496-18131123[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 3.9e-15 3e-11 44.3 0.0 7 70 699 760 695 765 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	3.9e-15	3e-11	44.3	0.0	7	70	699	760	695	765	0.89

Sequence Information

Coding Sequence: ATGTCGGAGGAAATGGCGGTGTCTGATAACACAACTGGGGACGAAGCTAAAGTTAGCAACGATGAGGCGACGACGCCGACTGTGGCGGAGCCCGAGGAGGTGGCGGTGGAGACGCCAATCGAGCCTGTAGTTCCTCCGGTCGTGCAGCCCCCAGCTTTGGCGGAAGAAGATCCAGGCCCAGAAATAGAACCAAAGATCGAAAACAAACCAGAAGTGAAAGTAGAACCAGAATCTGAAAACATAGATGTACCAATAGAGACCCCAGAATTTGACGTAGAAATTAAGAAGGAGGACGAAGAAGATGTGAAATTTGAAATTGAGACAGTTGAGCATAATATTGAGGAAGACATTAAGAGAGGAATCAAGCGGAGAGCTTCGTCCGCATTCAGTGATGTTGATGATGAGGAGTTTAAAGGCTTTGATGAAATCAAACTTGAGGTTAAGGCTGAGGACTACAGTCGTATATTGGAGCGACTGGAGGCGGAGGTGACAGCAGCCAGCAAGGACCTGGTGCCACTGAGGACCGTGATGGCTACGCCCCCCGCACCCGGCAGAGCCTCCAAACGACCGCGTAAAGACACTGACGGATCCAGGCCATCATCAGCTTTATCTTCAAGATCTGACGGCGACGGCGCTACTGATgtGCCTCCTGAGAAAATGAaacttaaaaaacaaaagaggACTAACCTCAAATATACCAAAGAAGCACTGGCTCAAGCTGTTCAGGCAGTCAGAACAAAAAGGAAAGGCATTAGAAAAGCTTGCCGGCAGTATGGCGTTCCTCCCACAGTCCAGGACCGACCCTCAGGTAGGGCTAAGGAACAAGCTCGGAGAGTAGGACCAGAGCCCATACTAGGCATTGATGGTGAACAAAAAGTAGTGGAATGGATCAAAGAATTAGCCAAGTGTGGGTTTTCTCCTAGTTTGTTCCCAGAAGGGTGCCCTAGAAAACAATGGTACTTAGGTTTTCTTAGGAGGCATCCGGAGATCAGCATAGCGCCTAAAGGAATTAACAAAGACAGCGAAGTGGCAACAGAAAGCTTAAAAAAGAAATGGTTTAAAGATCTTGAAGCTTTTTTGACTGAAAGAAGAATGACGGACATTATGAAAGATCCTGACAGAATATTCAATGCTGGTGAGACTAGATTTTCATTAACTCCAAAATCAGGTAAACTCCTCACCCCGGAAGGCTACGAAAATGTTAACATGTATAAAAgaggaaatgaaaaaaaaacacttacggTTTTAATAATGATGTCTGCATCGGGTACGGTTTGCCCTCCGCTTTTGGTGTTTCCGTGCAGTAGACCCTCAAAACCGATTTTAGACAATGTACCAGGTGATTGGCTCGTAGGAAGATCTGATTCAGGTAGGATGGGATTAAGTGTATTTTACGAATACTTTACTAACGGCTTTAATAACTGGTTAGTGGAAAATAAAGTCAAAAAACCAGTAATTGTTTTTGTAGATGGGcataaatcaaataataatatgtcaaTGCCTTTAAGTAAATTTTGTGAAGGTAATGGTATCATTTTATATGCTTTACCACCAAATACAACTCATCAAATCATGCAACCAGCTGAGGTTAGTGTGTTAAGATATTTAAAACAAGACTGGAAAAATACCCTTAAAAACTGGCAAGCCAAACCCGAAAACCTTAAAAAAACTGTGACGAAGAAAAACTTTAGCAAAGTGTTAAAAGATATCCTGGATACAGATATGACACAAACTATAAGGAACGGATTTAGAAATTGTGGGCTATTCCCGTTTGGTGGAAATGCAGTGGATTTCACGAAATGCGTAGTGAACATTCGAGAAAGAAGGCAGGAGAGGTCACTATCCTGCGCTGTGTTCACAAAACGAGACTTTTCATCTGCaataaaagtgatttttttaataaaggacAATTTGGTAAAGAATGGGATTGATCCAGATACGGTTTGCAATGAAATAGAGTTGGCAAAATCAACCTTCAACAAACATCGTCTGATAATTGAAGGTTCGATCCAGAAAAATAATAGCGCCAGTGCAACCTCATCGCCCGCACAACGAGGCGGTCGCCGAGCTACCATTGAGATGTCCTCTCCCTTACTGCGAGTACCTTTGGAACGTGGCTGGAAGAGAGAGCTCGTGTACCGCGCGGCGCTCGATGCTCATTCGAGGCGTAATGCCGATATCTATTACTATACGCCGTATGGGAAGAAGCTGCGCTCTACTAGAGAAGTCTCAGAACATCTTTCCGGTACGGGATTGACTGTAGATCACTTTTCCTTCTTCAAAGAACCGCTCGGAGTCGACGACCctgaaaaagaaataataagAGACGCAAAACTAATGCGTCGCGTGGACTCCCCGGTTGCGGCGACCGTTCAACCCGTTCAGGTGGAAGGCAAAAGGACACCTAAGCCAAAAGTGCCCAAGGGAGCTAGTCCTGAACCTGTGCCTCCGGCCACCGCTGCAGCTGCGAACAAGTCACCACCAGCTAAGATAAAGGTGAAATCAGTGGGTTCCCGACTAAGCAACAGCGCACCGCCAGCAGCGCCCACGCCACCCGCCAAACAACAAAAGAAACCACCGTCGCAACCGCCCCAACAACAACAGCCACCTCAGCCACAACAACTACCACCGCCAACAACCGTCAGCAACACAGACAACAATAACTCTGCCGCGTGGAAGAAACCGAGGCCTCCGCCCCCCACGCCGCCGCCGCTGCAGGGCCGCCCGCCCGTCGAGGCGGCGCCCGAGCCCCCCAACATAAGCTTCGCCGCTCAAAGCCCGGAGGCTCCCCGCTCGGCCGCGGTACAGCCGTGCTCGATGTCGTGCGGGCGCGGCGCCGTGCCGTCGCTGTCGTGCGCGGCGTGCCTGTGTCTGTACCATCCCGTCTGTGCGGGCTATATGCACGCCGCGCCGCCTGACCCGTTCTTTTGCAAGAACTGCCGCAAAACATCATCCCCGCCGATCGAGCCGCCGCCCCTCACTCACAAGTCCGGTATAACGACCACCAGCATACCGGTCCCGGTGCCCATTCCCGTGCCGGTCCCGGTGCTCGCGCCGGTACCGAGACGCGTTCCAGTGCCGGTACCGGTTCCCGTGCCGGCTAAAGTGCCGAGGGATAAGCGGGTGCTCCTGAGGATGAAGGTAGCAGGCGGCACCCCAGACGGCGAACGCGTATGGGCCGTCGCAGGCACGCCTCCTGTGTTACCTGCCGCCCCGGCCCCCGCGCCCATACCGGCCCCCTTACCGGTACCAATACCGGTACCAGTGCCAGTCCCAGTACCCGCTGCCGTAGCCGCACGAGGCAGGGCCCCGCGCCCCGCCCTGCCGCAGGGACTGGCCATACTGAATGGAAGACGCTTCGTGGTCGTGCCAAGGAATATGGTGCATGCTGGTGCTGGACATGCTGCTAAATGA
Protein Sequence: MSEEMAVSDNTTGDEAKVSNDEATTPTVAEPEEVAVETPIEPVVPPVVQPPALAEEDPGPEIEPKIENKPEVKVEPESENIDVPIETPEFDVEIKKEDEEDVKFEIETVEHNIEEDIKRGIKRRASSAFSDVDDEEFKGFDEIKLEVKAEDYSRILERLEAEVTAASKDLVPLRTVMATPPAPGRASKRPRKDTDGSRPSSALSSRSDGDGATDVPPEKMKLKKQKRTNLKYTKEALAQAVQAVRTKRKGIRKACRQYGVPPTVQDRPSGRAKEQARRVGPEPILGIDGEQKVVEWIKELAKCGFSPSLFPEGCPRKQWYLGFLRRHPEISIAPKGINKDSEVATESLKKKWFKDLEAFLTERRMTDIMKDPDRIFNAGETRFSLTPKSGKLLTPEGYENVNMYKRGNEKKTLTVLIMMSASGTVCPPLLVFPCSRPSKPILDNVPGDWLVGRSDSGRMGLSVFYEYFTNGFNNWLVENKVKKPVIVFVDGHKSNNNMSMPLSKFCEGNGIILYALPPNTTHQIMQPAEVSVLRYLKQDWKNTLKNWQAKPENLKKTVTKKNFSKVLKDILDTDMTQTIRNGFRNCGLFPFGGNAVDFTKCVVNIRERRQERSLSCAVFTKRDFSSAIKVIFLIKDNLVKNGIDPDTVCNEIELAKSTFNKHRLIIEGSIQKNNSASATSSPAQRGGRRATIEMSSPLLRVPLERGWKRELVYRAALDAHSRRNADIYYYTPYGKKLRSTREVSEHLSGTGLTVDHFSFFKEPLGVDDPEKEIIRDAKLMRRVDSPVAATVQPVQVEGKRTPKPKVPKGASPEPVPPATAAAANKSPPAKIKVKSVGSRLSNSAPPAAPTPPAKQQKKPPSQPPQQQQPPQPQQLPPPTTVSNTDNNNSAAWKKPRPPPPTPPPLQGRPPVEAAPEPPNISFAAQSPEAPRSAAVQPCSMSCGRGAVPSLSCAACLCLYHPVCAGYMHAAPPDPFFCKNCRKTSSPPIEPPPLTHKSGITTTSIPVPVPIPVPVPVLAPVPRRVPVPVPVPVPAKVPRDKRVLLRMKVAGGTPDGERVWAVAGTPPVLPAAPAPAPIPAPLPVPIPVPVPVPVPAAVAARGRAPRPALPQGLAILNGRRFVVVPRNMVHAGAGHAAK*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00375144; iTF_00036747; iTF_01441118; iTF_01440930;
90% Identity: iTF_00375144;
80% Identity: iTF_00375144;