Basic Information

Gene Symbol
-
Assembly
GCA_946251865.1
Location
CAMIUE010000591.1:393834-398512[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.0002 0.023 16.5 0.1 2 23 184 205 183 205 0.97
2 11 5e-05 0.0059 18.4 0.7 1 23 212 234 212 234 0.98
3 11 0.82 97 5.1 2.4 1 22 239 260 239 261 0.86
4 11 0.00048 0.056 15.3 2.2 1 23 267 288 267 288 0.99
5 11 0.29 35 6.5 0.1 2 23 294 315 293 315 0.95
6 11 0.028 3.3 9.7 4.4 1 23 320 342 320 342 0.98
7 11 0.00024 0.029 16.2 1.0 2 23 349 370 348 370 0.97
8 11 1e-05 0.0012 20.5 0.5 1 23 376 398 376 398 0.98
9 11 0.0002 0.023 16.5 1.8 1 23 404 426 404 426 0.98
10 11 0.0039 0.46 12.4 0.1 1 23 432 455 432 455 0.94
11 11 0.0048 0.57 12.1 3.1 2 19 462 479 461 485 0.92

Sequence Information

Coding Sequence
ATGGCGAGCCGAATACTATTTGAAGATGAAATTGATGaccaaaatctaaataaaactaacaaacCCAAACTGAATGAAGAAATGACAATAAAAGAAGAAGATCCAGCAGATGACGGTATCTGCAGTCCAGATCCTAGTCAAGGAAAAGAACACCAGGAGTTTACAGAAACTAATTCTGAAACAGTTAATACTACGGAGcctagtaataaaaatattgaaatagaaaatgtaatctttctcggcagtcgggtaaaaacaagtTATGAAGTTCCAATTGAGCAAGAGGGCAATATTGCTCAAGGTGAGGGTAATGTTATCATAGTTGGAGGGGGTAAAGttaagagaaaaaataaaagtgagCTGGAGTTGCTTGGTATAGATATAAAGGAGAATTATGAAGATTTAGACGCTGAATATGATGTGTTTGGAGatgaaagtaaaatatttagaaaGTATAAATTGAGGAAAACTGAGCAACCtATCTCATATAAGGAGCCAGAGGACATCAAACCCAAGCGCCGCATCAGTACAGATGATGAAACGGATTTGACATGTCCCGTTTGCTATCAAGAGTTTGAAAACAAGATGGCGTTACTGAACCACCTCCGAATCCATAACAAAACTGTACACGAATACACCTGCTCATTATGCTCCAAGAAATTCGAGAAAAATGCAGACTTAATTGCCCACAGAGAAAAACATAGCTCAGAGTCTTTTCTCTGTCAGGAATGCAAACTAGCATTTTCAAACTACTGCGATTATTTACTACACAACTATGAGCATTTGAGCCAACCCCATTTCAAATGCCAAGAATGTGGACTACGCTATCGAAAATCAGTCTATAAAAAACACATTATGACTCATTTTAAAAATCTACTGTCCTGCGACTTATGCTCTTTCGTTGCCAACGGCGAATACAAGTTACGGGCTCATATAAATCAGCATAAATACGTGGGATTTGTCTGCGTAGAGTGTGGAAAAGTGTGCAAATGCAAAAAAGATTATGAATATCATATGAGCATGCATACTGGGGTTAAGAGGATCCAGTGTCTTTACTGCGGAGCATGTTTTCGCAACCTTAGCGCGAGGCAAGTGCACACTAGAATACACACAGGTGAAAAACCTTTTACTTGTGACATATGTGGGCTCAAAGTTAGGCAATGGACAGATTTGAAACGACATAAAGAGACTCATAGCACGGAGAAAAAGTACGCCTGCGATTTGTGTGGAAAGAAATACTTGCACAAATATTATCTTGTGATTCATATGCGGTCTCATACAAATAAGTATTTGTATGAGTGTCCAGAGTGTGATGCTAAGTTTGTCGGTGTGGCTGGGTTGAAGACTCATACGATGTTTAAGCATATGAGTGAGCGCCCTATTGAGTGTACGCTTTgtgataaaaagtttattaataataatcagtATCGGAAACATTGTAGGGCAAAGTATCATTTAAGAAATGTGTATGGGAATAATACTGATAAAAAGAAGAAAGATGAATAA
Protein Sequence
MASRILFEDEIDDQNLNKTNKPKLNEEMTIKEEDPADDGICSPDPSQGKEHQEFTETNSETVNTTEPSNKNIEIENVIFLGSRVKTSYEVPIEQEGNIAQGEGNVIIVGGGKVKRKNKSELELLGIDIKENYEDLDAEYDVFGDESKIFRKYKLRKTEQPISYKEPEDIKPKRRISTDDETDLTCPVCYQEFENKMALLNHLRIHNKTVHEYTCSLCSKKFEKNADLIAHREKHSSESFLCQECKLAFSNYCDYLLHNYEHLSQPHFKCQECGLRYRKSVYKKHIMTHFKNLLSCDLCSFVANGEYKLRAHINQHKYVGFVCVECGKVCKCKKDYEYHMSMHTGVKRIQCLYCGACFRNLSARQVHTRIHTGEKPFTCDICGLKVRQWTDLKRHKETHSTEKKYACDLCGKKYLHKYYLVIHMRSHTNKYLYECPECDAKFVGVAGLKTHTMFKHMSERPIECTLCDKKFINNNQYRKHCRAKYHLRNVYGNNTDKKKKDE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00623438;
90% Identity
iTF_00374823; iTF_00375916;
80% Identity
iTF_00374823;