Basic Information

Insect: Coenonympha glycerion
Gene Symbol: NR2E3
Assembly: GCA_963855885.1
Location: OY979631.1:11837374-11841630[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.94 5.3e+03 -2.9 0.1 60 86 92 117 48 143 0.31

2 8 1.6e-17 8.9e-14 52.3 0.1 217 326 156 257 150 263 0.90

3 8 1.2e-06 0.0067 16.5 0.0 289 326 269 306 261 313 0.92

4 8 2.6e-06 0.015 15.4 0.0 289 326 318 355 309 365 0.92

5 8 1.4e-06 0.0081 16.3 0.0 290 326 368 404 360 414 0.92

6 8 1.6e-06 0.0092 16.1 0.0 290 326 417 453 410 456 0.92

7 8 2.5e-06 0.014 15.4 0.0 289 326 465 502 456 514 0.92

8 8 5.5e-18 3.1e-14 53.8 0.0 290 404 515 657 505 659 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.94	5.3e+03	-2.9	0.1	60	86	92	117	48	143	0.31
2	8	1.6e-17	8.9e-14	52.3	0.1	217	326	156	257	150	263	0.90
3	8	1.2e-06	0.0067	16.5	0.0	289	326	269	306	261	313	0.92
4	8	2.6e-06	0.015	15.4	0.0	289	326	318	355	309	365	0.92
5	8	1.4e-06	0.0081	16.3	0.0	290	326	368	404	360	414	0.92
6	8	1.6e-06	0.0092	16.1	0.0	290	326	417	453	410	456	0.92
7	8	2.5e-06	0.014	15.4	0.0	289	326	465	502	456	514	0.92
8	8	5.5e-18	3.1e-14	53.8	0.0	290	404	515	657	505	659	0.97

Sequence Information

Coding Sequence: ATGGTATGTACTGGGAGCAACGACGAACTTTATGATGGCGCTGTCCCCGGCGCGCTACCCGCTGCTGTCGCCGCACtacgcgccgctgccgccgccgcagccgccgcaacAGCCGCAGCCAGACTCCTCGCACGACCACCACGACGGCGGCCACGCGCACTCCGACAGCGATGGTATGTACTGGGAGCAACGACGAACTTTATGATGGCGCTGTCCCCGGCGCGCTACCCGCTGCTGTCGCCGCACtacgcgccgctgccgccgccgcagccgccgcaacAGCCGCAGCCAGACTCCTCGCACGACCACCACGACGGCGGCCACGCGCACTCCGACAGCGATGATGACAGTATTGACGTGACCAATGAAGAGGATTCCACATCGTATTCCCCTCCAGCCGTATCCAGCTATTCCCAAAGTTGTATACCATATGGGCCACTTGGCGTAGAAAGTGCGGCGGAAACGGCGGCGCGCTTGCTATTCATGGCGGTCAAATGGGCCAAAAACTTACCTTCCTTCGCCAGCCTTGCCTTTCGGGATCAAGTGATTCTCTTAGAAGAAGCGTGGTCGGAACTGTTTCTGCTGAACGCGATTCAGTGGTGCGCGCCGCTGGACGCCGCGTGCGCCGCGCTCTTCGGCACCGAGCAGACCGACCAAGagaaTGGCACGTCGTCGGTGCTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCTATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCGCGTCGTCGGTGCTGAGCAGGCTCCGCTCTGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGTATGAAGGCTATCGCGCTGTTCAAGTGCGGTAAATATCCACTATCCATCAACATTGTAGAGAATGGCGCGTCGTCGGTGCTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGCATGAAGGCTATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGACTGGCGCGTCGTCGGTGCTGAGCAGGCTCCGCTCTGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGTATGAAGGCTATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGACTGGCGCGTCGTCGGTGCTGAGCAGGCTCCGCTCTGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGTATGAAGGCTATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGAATGGCGCGTCGTCGGTGCTGCGCAGGCTCCGCTCCGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGTATGAAGGCTATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGACTGGAGCATCGTCGGTGCTGAGCAGGCTCCGCTCTGTGGTGTCGCGCTACCGCAGCGTGCTGGTGGATCCCGCGGAGTTCGCCTGTATGAAGGCTATCGCGCTGTTCAAGTGCGGTAACTATCCACTATCCATCAACATTGTAGAGACTGGCGCGTCGTCGTTGCTGCGCAGGCTCCGCTCCGTCGTGTTATCGCAGCAAACCCGAGGCCTAAAGGACCCGCTGCAGATCGAGAACCTGCAGGACCAGGCGCAGGTGATGCTGATGACGCACGCGCGCGCGGCGCACGGTGCGGCGCCCGCGCGCTTCGGccgcctgctgctgctgctgcctcTGCTGCGCCTCGTGTCGCCGCAGCAGCTGGAGCGCGAGTTCTTCTCCAAGACCATCGGCCACACGCCCATGGAGAAGGTCTTGGCTGACATGTACAAGAACTGA
Protein Sequence: MVCTGSNDELYDGAVPGALPAAVAALRAAAAAAAAATAAARLLARPPRRRPRALRQRWYVLGATTNFMMALSPARYPLLSPHYAPLPPPQPPQQPQPDSSHDHHDGGHAHSDSDDDSIDVTNEEDSTSYSPPAVSSYSQSCIPYGPLGVESAAETAARLLFMAVKWAKNLPSFASLAFRDQVILLEEAWSELFLLNAIQWCAPLDAACAALFGTEQTDQENGTSSVLRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGASSVLSRLRSVVSRYRSVLVDPAEFACMKAIALFKCGKYPLSINIVENGASSVLRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVETGASSVLSRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVETGASSVLSRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVENGASSVLRRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVETGASSVLSRLRSVVSRYRSVLVDPAEFACMKAIALFKCGNYPLSINIVETGASSLLRRLRSVVLSQQTRGLKDPLQIENLQDQAQVMLMTHARAAHGAAPARFGRLLLLLPLLRLVSPQQLEREFFSKTIGHTPMEKVLADMYKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00354137; iTF_00354141; iTF_00354270;
90% Identity: iTF_00354137; iTF_00354141; iTF_00354270;
80% Identity: iTF_00354137; iTF_00354141; iTF_00354270;