Ccae004385.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Chrysops caecutiens
Gene Symbol
RHOBTB1
Assembly
GCA_963971475.1
Location
OZ020567.1:24840689-24844300[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 5e-08 2.7e-05 25.7 0.0 3 45 256 302 254 331 0.78
2 3 5.8e-07 0.00031 22.2 0.0 49 101 391 442 372 449 0.86
3 3 1.3e-18 7.3e-16 59.7 0.0 6 103 474 570 470 577 0.92

Sequence Information

Coding Sequence
ATGGATAATGAACAACCGCACCAAGAGTTGGTGAAATGTGTACTTGTTGGTGATACAGCAGTTGGAAAAACAAGGCTTATTTGCGCCAGAGCATGTAACAAACATGTCTCATTATCTCAACTTTTATCTACTCATGTACCAACAGTGTGGGCCATTGATCAATACAGAATATACAAAGATGTATTAGAAAGATCATGGGAAGTTGTCGACGGAGTAAATGTATCATTAAGGCTATGGGATACATTTGGGGACCATGAGAAAGATAGACGTTTTGCTTATGGAAGATCGGACGTAGTGCTACTTTGTTTCTCAATAGCAAGTCCTATATCCTTAAGAAATTGTAAAGCTATGTGGTATCCTGAAATTCGAAGATTTTGTCCCGATACACCTGTTATATTAGTAGGGTGTAAAAACGATTTAAGATATATGTATCGCGATGAAACATACTTATCATATTTTGGCGATCGGAGTCCATTTGTTAGAGCGGCTATAAAAAGTGATTTAGTAATGCCGGATGAAGCTAGAGCTGTTGCCAAAGAACTAGGGGTGGCTTATTATGAGACGAGTGTCTTCACTTACTTTGGAGTgaatgaagtttttgaaaatgcaaTTAGGGCTGCCCTTATTGCTAGGAGACAACAAAGGTTTTGGATGACAAACCTTAAAAAAGTACAAAGACCACTTCTTCAAGCACCATTTAGACCACCAAAACCTCCGCCACCAGAAGTTACGGTGGTAACAGGAACTCATAAAAAGGATATGTTCAATATGTTGAAATCACAGTGTTACACGGATTTGATTTTAATCATAGGATCGGCAAGATTTGCCGTGCACAAATTCATGCTTGCTGCCGGATCAAATACTTTTTATCGTTTACTAACCACTGAATTATCTGATATGGGTGGTAGAAGTAGCAGTGAATCGAGTATGGTAAGTTCCACATTTGGAGAAACTACAGCTGCCGATTTTAATGATGATACAGAGTATTTAATACGAAATGAATCGAAACCTTCAAGaATGTGGGAACAGCTCAAACGCCGATCCAGCTATCAAGCCCTTCCACTCGTAGAATCAAAAAAGCCAACAGATTTGTGTAAAGATCTCCATCATccgatttttcaaaatatacgtgTTGTTCAGgCTGATACAGGTCGTGGATTACATACAACTCAAACAATTGTAACTCTAACCAAAATTATCACTCCACAAGCTATGAATCAatgtttaaagtttatttacaCTGGCACAATTGAGAAGGAATTTCATAATTTACAGGAAATAAAGCAAGCTGCTGACTTCCTTGAACTTCCACAATTAACGCTCTTACTTTCAAAAACACAAGCGAGCTTATCCAAAAACGAAGAACCTGCTCAACATTATTCAGCTTGGATTAAAGATAatcttgaaaaatattgtatcAACAATGGATTCTTTGGCGATGTAACCTTCGAATTAGATGATGGACACATGAAATCTCATAGGGCCGTTCTAGTTGCTCGATGTGATGTTATGAGAGCTATGCTAAATGGTGATTTTAGAGAAGCACATTCAAGTGTGATTGTGTTTCCTGGTGTAACAGTGTACACATTCCATAAACTTCTCTGTTATTTATATACAGATGAAATACCACCAATATCAGCTGATAAATGTCTGAATTTATTAGAGTTAGCCAATAGATTATGTTTACCTAGGTTATTAAATCTTGTAGAATGCCGTGTCATAGAAGATTTAACAAGTATATCtcaaaaagaaacaaatgaaactgTAGAACATTGTTTAAAATTACTTGAACCAGTTAAGTTACACAATGCACATCAACTTGCTGAATGGTGTATGTCATACTTATGTGTTAATTACAACATCATTTGCAAATTTGCATTGAAAAGTTTAAAGGCACTACATCAAGATAATCAAGAATATTTAAGAGAACATCGTTGGCCCCCAGTATGGTACTTGAAAGACTACGACTATTATCAGCGATGcattaatgaaatgaaaaaggaaCTGAAGGAAGGAAGAGGTGAATCTTCAAGCGATGATGAAGGATGCCTTTGTTTCTCAGGAGTATTTTCTTGGCTAGTAGGCAAATCTCGGAGGATTGAATCAACAAATTTGACCAGAGCCAATGAAACCAGTGAACAGTCAAATGCGGATGCACATATGTTCAACACATCCGGGCACTGGAGATCACTGCGATTTATTGTGATCTTGCCCgtattgatttgttttatttgtacaattttgagcattcttattttgtttcagATATACACATAA
Protein Sequence
MDNEQPHQELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSLRLWDTFGDHEKDRRFAYGRSDVVLLCFSIASPISLRNCKAMWYPEIRRFCPDTPVILVGCKNDLRYMYRDETYLSYFGDRSPFVRAAIKSDLVMPDEARAVAKELGVAYYETSVFTYFGVNEVFENAIRAALIARRQQRFWMTNLKKVQRPLLQAPFRPPKPPPPEVTVVTGTHKKDMFNMLKSQCYTDLILIIGSARFAVHKFMLAAGSNTFYRLLTTELSDMGGRSSSESSMVSSTFGETTAADFNDDTEYLIRNESKPSRMWEQLKRRSSYQALPLVESKKPTDLCKDLHHPIFQNIRVVQADTGRGLHTTQTIVTLTKIITPQAMNQCLKFIYTGTIEKEFHNLQEIKQAADFLELPQLTLLLSKTQASLSKNEEPAQHYSAWIKDNLEKYCINNGFFGDVTFELDDGHMKSHRAVLVARCDVMRAMLNGDFREAHSSVIVFPGVTVYTFHKLLCYLYTDEIPPISADKCLNLLELANRLCLPRLLNLVECRVIEDLTSISQKETNETVEHCLKLLEPVKLHNAHQLAEWCMSYLCVNYNIICKFALKSLKALHQDNQEYLREHRWPPVWYLKDYDYYQRCINEMKKELKEGRGESSSDDEGCLCFSGVFSWLVGKSRRIESTNLTRANETSEQSNADAHMFNTSGHWRSLRFIVILPVLICFICTILSILILFQIYT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01300978;
90% Identity
iTF_00176500;
80% Identity
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