Basic Information

Insect: Chrysolina haemoptera
Gene Symbol: topi
Assembly: GCA_958298965.1
Location: OY282590.1:5537226-5543083[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0033 0.51 12.6 2.1 2 21 98 117 97 118 0.94

2 13 4.5e-06 0.00069 21.6 1.1 1 23 141 163 141 163 0.97

3 13 0.014 2.1 10.7 2.0 3 23 171 191 170 191 0.95

4 13 0.018 2.7 10.3 0.2 2 20 210 228 209 230 0.88

5 13 0.00064 0.099 14.8 1.1 2 23 281 302 280 302 0.97

6 13 0.0036 0.55 12.5 3.4 2 22 345 365 344 368 0.88

7 13 0.0011 0.17 14.1 0.4 1 23 498 521 498 521 0.97

8 13 0.0051 0.78 12.0 0.3 1 23 525 547 525 547 0.97

9 13 1.1e-06 0.00016 23.6 2.4 1 23 553 575 553 575 0.98

10 13 0.031 4.7 9.6 0.2 1 23 581 606 581 606 0.96

11 13 0.1 16 7.9 2.9 1 23 612 634 612 634 0.86

12 13 6.6e-06 0.001 21.1 0.3 1 23 640 662 640 662 0.98

13 13 4.4e-06 0.00067 21.7 2.2 1 23 668 691 668 691 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0033	0.51	12.6	2.1	2	21	98	117	97	118	0.94
2	13	4.5e-06	0.00069	21.6	1.1	1	23	141	163	141	163	0.97
3	13	0.014	2.1	10.7	2.0	3	23	171	191	170	191	0.95
4	13	0.018	2.7	10.3	0.2	2	20	210	228	209	230	0.88
5	13	0.00064	0.099	14.8	1.1	2	23	281	302	280	302	0.97
6	13	0.0036	0.55	12.5	3.4	2	22	345	365	344	368	0.88
7	13	0.0011	0.17	14.1	0.4	1	23	498	521	498	521	0.97
8	13	0.0051	0.78	12.0	0.3	1	23	525	547	525	547	0.97
9	13	1.1e-06	0.00016	23.6	2.4	1	23	553	575	553	575	0.98
10	13	0.031	4.7	9.6	0.2	1	23	581	606	581	606	0.96
11	13	0.1	16	7.9	2.9	1	23	612	634	612	634	0.86
12	13	6.6e-06	0.001	21.1	0.3	1	23	640	662	640	662	0.98
13	13	4.4e-06	0.00067	21.7	2.2	1	23	668	691	668	691	0.98

Sequence Information

Coding Sequence: ATGAACAATCTCGATAAAATCGTGATCAAAGTGCACAAGATCGCAGAAAATGGAACGGTGATTTATTCATCGAGATTTGAAATGGATCCAAATACAAAAGAACCCATTTCAAGTACTTACCTGTCGCCAGAAAAAGTGAGTTTCATTCTATCTTCTGAAAATAAACTGACTCTCAATTACCAGCGCTTTGAAATTGAAGAGGAACACCTGAAATGCCTCAAATTGGATGAAAGCGAAGATAGTGTGCTACCGGTGTCAGGAAAACTGATTCTGAGTATTCCCACAATGATAAGATGCCAGAATTGCGAAACCAACTTCCCTACAAAATATCAGTATCAAAGGCACCAGTGCGAGTTCAACGCAGACAAAGTTGTCTTCAAAACGGACTTTGAACACTTGGACAAAGGCGTTCGCGTGAAATATGTTTGCACCAATTGCGACAAACAGTTCGTAAGCAAAAGCAATCTTGACCGCCATCGAGTAAGCCATGAAAACACTCAGGAAAATATCTGCGAACATTGCAATAAACAATTCGTGAGCGAAAATAGACTAAGGATTCACAAAGAGAACCACTGCAAAAAGGCCGGTGACATTTCTAAGTTCTACAGAAGTGATGTAACGGTGtggaaatgtaaaaaatgccaTGAAGTTTTTTCTTCCCCTGTAACGGCGAATTACCACGTATCAATTTGTTCCGAAATCGTCGAACATGACTCTGACGAACACGCAGAACTAGCTGCAGAAGAAGAAGATAACGTTGCCTCGAATTCAAACGACGAAAACGACAAGGACGGCTTTGCCGACGAAAACATCGAAAAAATGTTGACGGAAATTTTGTTGCAATGCGAGTTTTGCAATAGGACTTATGCCGAGAAGAACTTGCTGTTAATGCACCAAAGAAAGCACACCACGTTGAAAAACTACGAATGTGTGAACTGTTGTCAAGTATTCGACTCGTACGCTACAGCCGCGCAACACTGGATGAGAAAATGCTCCGACTACGTAAGTCTTTTTTACCTTCCAAAGCTCACTTATTGCGAATATTGCGATAGAACCTTCAAATCCCACGAGCTCTTGTACACGCACAAGATAAAAAAGAAGCATTACACTTCCAAGTTGCATAAGGTGGACGTTGACGCATCATCCGTGACAGAGGAAAAAGATACCGGCCACAAAGAAAAATGCCTCGACAACAAGGAAATCTTGAACAAGCTCATAGAAGACGTCCTGAAAACTCTCGATGTTCCTGTTAACAAAATTGCCATCACCCAAAATTCGATCGTTGAGGAAAACGAAGGGAAAAACGTTGATGATGAGGGGAACGCTATGATGGAGATCAGCGAAATTAAAACTGAAAACGAAGAAACCGGATGCACCGAAAGCAATAACGAAGTAGCGGAGAAGAAGAAAAGAGGTAGAAGACGCAAATGGCCCAGGAACCAATGTGCCggtctgaaaaaaatatgttccgaaGTTAATCATGGGTTCAAGTACCAGTGTGAACGCTGCGTCAAAGTTTTTGATAAGACTGGAGATCTGGAGACGCACCGTGAGAAAGAGCACGCTTCTAGTTATTCCTGCGAAGAATGCGGACAGgTTCTGCACAGTGCCAAGTCCTTGCTGATTCATAGTCGCGCTCACAAGAGTCTGAAACCATACGTTTGTGAAACTTGTGGTCGTAGCTATTCTCAAACTTCCCATCTTTGGCAACATATGCGATTCCACCAAGGAATAAAACCCTTCGCTTGTCCACATGAAGGATGCGAAGCCAGATACACCATCCGACCGGATCTGAAAGACCACATCAGAAAAGTCCACACGAGAGAGCGTCCCTTCAAGTGTAACGTTTGCGACAAGTGTTTCCTGACGGGCTCTGTTTACTACCAGCATCGGTTGATACATACCAATGACAGACGATACGCCTGCGATCTTTGTCCGAAGAGATTCTTCCGAGCTGACGCTTTGAACAACCACAGGAGGATCCATACCGATGAAAGGCCGTATCCGTGCCATGTTTGCGGAAGAGAGTTTAGGCAGAAAGGCGATCGTAACAAACATTTACGAACGCAACACCCGGATAGCTTCCTGGTTTGA
Protein Sequence: MNNLDKIVIKVHKIAENGTVIYSSRFEMDPNTKEPISSTYLSPEKVSFILSSENKLTLNYQRFEIEEEHLKCLKLDESEDSVLPVSGKLILSIPTMIRCQNCETNFPTKYQYQRHQCEFNADKVVFKTDFEHLDKGVRVKYVCTNCDKQFVSKSNLDRHRVSHENTQENICEHCNKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCKKCHEVFSSPVTANYHVSICSEIVEHDSDEHAELAAEEEDNVASNSNDENDKDGFADENIEKMLTEILLQCEFCNRTYAEKNLLLMHQRKHTTLKNYECVNCCQVFDSYATAAQHWMRKCSDYVSLFYLPKLTYCEYCDRTFKSHELLYTHKIKKKHYTSKLHKVDVDASSVTEEKDTGHKEKCLDNKEILNKLIEDVLKTLDVPVNKIAITQNSIVEENEGKNVDDEGNAMMEISEIKTENEETGCTESNNEVAEKKKRGRRRKWPRNQCAGLKKICSEVNHGFKYQCERCVKVFDKTGDLETHREKEHASSYSCEECGQVLHSAKSLLIHSRAHKSLKPYVCETCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCNVCDKCFLTGSVYYQHRLIHTNDRRYACDLCPKRFFRADALNNHRRIHTDERPYPCHVCGREFRQKGDRNKHLRTQHPDSFLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00328527; iTF_00756003;
90% Identity: iTF_00328527;
80% Identity: -