Basic Information

Insect: Gonioctena quinquepunctata
Gene Symbol: topi
Assembly: GCA_018342105.1
Location: JAFIRS010002473.1:9946-24636[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0027 0.31 12.6 2.1 2 21 101 120 100 121 0.94

2 14 7.7e-07 8.8e-05 23.8 1.6 1 23 146 168 146 168 0.98

3 14 0.0086 0.99 11.0 2.0 2 23 175 196 175 196 0.95

4 14 0.039 4.5 9.0 0.3 2 20 215 233 214 235 0.85

5 14 0.00053 0.061 14.8 1.1 2 23 288 309 287 309 0.97

6 14 4.1 4.8e+02 2.6 0.0 1 12 315 326 315 335 0.86

7 14 0.003 0.34 12.5 3.4 2 22 352 372 351 375 0.88

8 14 0.00031 0.036 15.6 0.3 1 23 503 526 503 526 0.97

9 14 0.0056 0.65 11.6 0.3 1 23 530 552 530 552 0.97

10 14 8.8e-07 0.0001 23.6 2.4 1 23 558 580 558 580 0.98

11 14 0.025 2.9 9.6 0.2 1 23 586 611 586 611 0.96

12 14 0.086 9.9 7.9 2.9 1 23 617 639 617 639 0.86

13 14 5.5e-06 0.00063 21.1 0.3 1 23 645 667 645 667 0.98

14 14 3.6e-06 0.00042 21.7 2.2 1 23 673 696 673 696 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0027	0.31	12.6	2.1	2	21	101	120	100	121	0.94
2	14	7.7e-07	8.8e-05	23.8	1.6	1	23	146	168	146	168	0.98
3	14	0.0086	0.99	11.0	2.0	2	23	175	196	175	196	0.95
4	14	0.039	4.5	9.0	0.3	2	20	215	233	214	235	0.85
5	14	0.00053	0.061	14.8	1.1	2	23	288	309	287	309	0.97
6	14	4.1	4.8e+02	2.6	0.0	1	12	315	326	315	335	0.86
7	14	0.003	0.34	12.5	3.4	2	22	352	372	351	375	0.88
8	14	0.00031	0.036	15.6	0.3	1	23	503	526	503	526	0.97
9	14	0.0056	0.65	11.6	0.3	1	23	530	552	530	552	0.97
10	14	8.8e-07	0.0001	23.6	2.4	1	23	558	580	558	580	0.98
11	14	0.025	2.9	9.6	0.2	1	23	586	611	586	611	0.96
12	14	0.086	9.9	7.9	2.9	1	23	617	639	617	639	0.86
13	14	5.5e-06	0.00063	21.1	0.3	1	23	645	667	645	667	0.98
14	14	3.6e-06	0.00042	21.7	2.2	1	23	673	696	673	696	0.98

Sequence Information

Coding Sequence: ATGAACAATCTTGATAAAATCGTGATAAAAGTGCATGAAATCTCAGAAAACGGGATAGTGATTTCCTCTGCAAGATTCGAAATGGACTCAGGTGCGAAGGAATCAGTTATGACCACTTACCTGCCCCCCGAAAATGTGAGTTTCGCATTGTCGTCTGAAAATACATTAAACCTGAATTATAGAAGATTTGAAGTTGACGAGAACGACGAGGAAATTTTGAAATGCTTGAAAGTGGATGAAGTCGATGAAAATATTTTACCGGTTTCTGGAAAACTCGTTCTCAATATTCCTACGATGATAAGGTGCCAAAATTGTGAAACCAACTTTCCCACTAAATATCAGTACCAAAGACATCAGTGCGAATTCAATGCAGAAAAAGTCGTATTCAAACCTGATGTAGATTCCGACAATTTGGACAAAAGCGTTCGCGTTAAATATATTTGCCAGTTTTGCGATAAACAGTTCGTCAGCAAAAGCAATCTGGAACGTCATCAGTCTAGCCATGAAAATAATAAGGAAAACGTTTGCGAGCATTGCAATAAACAATTCGTAAGTGAAAACCGACTTAGGATACACAAGGAGAATCACTGCAAAAAAGCCGGTGATATTTCGAAATTTTATAGAAGCGACGTTACAGTGTGGAAATGCAAAAAGTGCCACGAAGTTTTTTCTTCTCTGGTAACGGCAAATTACCACGTTTCAATCTGTACCGAAATCGTAGAAATTGTCGACTCTGACGAACACAAAGAACTTGATCTCCAAGAGGAGCTGATCAAAGTCGCATCGAATCTCTGCGAAAATGATAAAGAGAACCTAGCGGGTTTTGACAACATCGAGAAAATGCTGACTGAAATTTTGTTACAGTGCGAATTCTGCAATAGAACTTACGCTGAGAAAAATTTACTCTTGATGCACCAAAGAAAGCATACCACCTCGAGAAATTACGAATGCGTGAATTGTTCCCAGGTTTTCGATTCTTTCGCTGTGGCTGCTCAACACTGGTTGCGGAAATGCTCCGAATACGTCAGTCTCTTCTATCTACCCAAGCTGACGTATTGCGAATATTGCGATAGGACTTTCAAGTCTCACGAGCTGTTATACACCCATAAAATCAAGAAGAAGCATTACACTTCGAAACTACACGAAGTGAATGCTGATGCGGAATCTGAGCAAGTCAAAGAAGACATCGGTCCCAGCGAAAAATGCCCGGATAATAAGGAAATCTTGAACAAGCTCATAGAAGATGTACTGAAAACGCTGGATGTTCCTGTTAACAAGATTTCTCTTACGCATAACCCCGGTTCCGAGGAGAATGCAAAGAAAAACTTGGACGTTGAAGGGAATCCCATGATGGACATTGCAGAAATAAAGACCGAGAGTGATGAAACGGAATTCAACCAAAACGAAGCCGCGGAGAAGAAGAAAAGGGGTAGGAGACGTAAGTGGTCGAAGAATCAGTGCCcacgtttaaaaaaattctgcTCCACAGTCGAAGGGGGCTTCAAGTATCAATGCGAACGGTGCGTCAAGGTTTTTGATAACACGGGAGATCTGGAGACACATCGGGAGAAGGAACACGCTTCCCGGTTTTCTTGCGAAGAATGTGGACaggtTCTACATAGCGCCAAGTCTCTATTAATCCATAGTCGAGCTCACAAGAGCCTGAAACCTTATGTGTGCGAAACCTGCGGACGCAGCTATTCTCAAACTTCTCACCTTTGGCAACATATGCGATTTCATCAAGGAATAAAACCGTTCGCCTGTCCCCACGAAGGGTGCGAAGCTAGATACACCATCAGACCCGATCTGAAGGACCACATCAGAAAAGTCCACACGAGAGAACGCCCTTTCAAGTGCAACGTTTGCGACAAGTGTTTTTTGACTGGATCCGTTTACTATCAGCACAGGTTGATACACACCAACGACCGAAGATACGCTTGTGACCTATGCCCGAAACGATTCTTCAGAGCCGATGCTCTGAATAACCACAGGAGGATCCACACGGACGAGCGTCCGTATCCCTGTCACGTTTGTGGCAGAGAGTTCCGACAAAAAGGCGATCGCAACAAACATTTGAGAACGCAACACCCAGATAGCTTCCTTGTTTGA
Protein Sequence: MNNLDKIVIKVHEISENGIVISSARFEMDSGAKESVMTTYLPPENVSFALSSENTLNLNYRRFEVDENDEEILKCLKVDEVDENILPVSGKLVLNIPTMIRCQNCETNFPTKYQYQRHQCEFNAEKVVFKPDVDSDNLDKSVRVKYICQFCDKQFVSKSNLERHQSSHENNKENVCEHCNKQFVSENRLRIHKENHCKKAGDISKFYRSDVTVWKCKKCHEVFSSLVTANYHVSICTEIVEIVDSDEHKELDLQEELIKVASNLCENDKENLAGFDNIEKMLTEILLQCEFCNRTYAEKNLLLMHQRKHTTSRNYECVNCSQVFDSFAVAAQHWLRKCSEYVSLFYLPKLTYCEYCDRTFKSHELLYTHKIKKKHYTSKLHEVNADAESEQVKEDIGPSEKCPDNKEILNKLIEDVLKTLDVPVNKISLTHNPGSEENAKKNLDVEGNPMMDIAEIKTESDETEFNQNEAAEKKKRGRRRKWSKNQCPRLKKFCSTVEGGFKYQCERCVKVFDNTGDLETHREKEHASRFSCEECGQVLHSAKSLLIHSRAHKSLKPYVCETCGRSYSQTSHLWQHMRFHQGIKPFACPHEGCEARYTIRPDLKDHIRKVHTRERPFKCNVCDKCFLTGSVYYQHRLIHTNDRRYACDLCPKRFFRADALNNHRRIHTDERPYPCHVCGREFRQKGDRNKHLRTQHPDSFLV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00329937;
90% Identity: -
80% Identity: -