Basic Information

Insect: Chironomus tentans
Gene Symbol: -
Assembly: GCA_963573255.1
Location: OY754304.1:9397634-9399696[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.05 2.6 8.9 1.0 2 23 22 44 21 44 0.94

2 18 0.0065 0.34 11.6 0.1 7 23 57 73 51 73 0.86

3 18 0.064 3.4 8.5 0.5 2 23 79 100 78 100 0.96

4 18 1.5e-06 8.1e-05 23.0 0.8 1 23 104 126 104 126 0.98

5 18 0.014 0.74 10.6 4.1 2 23 133 155 132 155 0.95

6 18 0.00046 0.024 15.3 1.6 1 23 163 185 163 185 0.95

7 18 0.0016 0.087 13.5 3.8 2 23 192 213 191 213 0.97

8 18 0.0038 0.2 12.4 1.1 1 21 218 238 218 239 0.96

9 18 0.004 0.21 12.3 0.5 1 23 334 357 334 357 0.96

10 18 0.0026 0.14 12.9 1.0 1 23 362 385 362 385 0.92

11 18 0.0071 0.38 11.5 0.9 1 23 396 418 396 418 0.94

12 18 0.0001 0.0053 17.3 0.4 2 23 425 446 424 446 0.95

13 18 0.0014 0.072 13.8 0.5 1 23 452 475 452 475 0.94

14 18 0.47 25 5.8 1.9 2 23 483 504 482 504 0.93

15 18 0.00052 0.028 15.1 4.3 1 23 513 536 513 536 0.91

16 18 0.00031 0.017 15.8 0.5 1 23 545 567 545 567 0.91

17 18 0.024 1.3 9.9 1.6 6 23 577 594 574 594 0.93

18 18 0.00045 0.024 15.3 1.3 1 23 600 622 600 623 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.05	2.6	8.9	1.0	2	23	22	44	21	44	0.94
2	18	0.0065	0.34	11.6	0.1	7	23	57	73	51	73	0.86
3	18	0.064	3.4	8.5	0.5	2	23	79	100	78	100	0.96
4	18	1.5e-06	8.1e-05	23.0	0.8	1	23	104	126	104	126	0.98
5	18	0.014	0.74	10.6	4.1	2	23	133	155	132	155	0.95
6	18	0.00046	0.024	15.3	1.6	1	23	163	185	163	185	0.95
7	18	0.0016	0.087	13.5	3.8	2	23	192	213	191	213	0.97
8	18	0.0038	0.2	12.4	1.1	1	21	218	238	218	239	0.96
9	18	0.004	0.21	12.3	0.5	1	23	334	357	334	357	0.96
10	18	0.0026	0.14	12.9	1.0	1	23	362	385	362	385	0.92
11	18	0.0071	0.38	11.5	0.9	1	23	396	418	396	418	0.94
12	18	0.0001	0.0053	17.3	0.4	2	23	425	446	424	446	0.95
13	18	0.0014	0.072	13.8	0.5	1	23	452	475	452	475	0.94
14	18	0.47	25	5.8	1.9	2	23	483	504	482	504	0.93
15	18	0.00052	0.028	15.1	4.3	1	23	513	536	513	536	0.91
16	18	0.00031	0.017	15.8	0.5	1	23	545	567	545	567	0.91
17	18	0.024	1.3	9.9	1.6	6	23	577	594	574	594	0.93
18	18	0.00045	0.024	15.3	1.3	1	23	600	622	600	623	0.96

Sequence Information

Coding Sequence: ATGAAAACGACAAAAGATACTCACAAACATGAAGGCAAGACAGGAAAATCTAAGAAAAGCCTTCAATGTGAAATttgtaaatcaattttaaaatcagaatattatttgaagaaaCACAAGGAAAGCAGACATCCTGAGCATCCACGGAACTACATCTGTGACTATGACGGAAAAGTGtttgcaaacaaaaattatttaaggatTCATATGGAAAGGCATCAACAAGAGATTCTGACATGCAATATATGCATGAAAGCGTACAATTCAAAGATCATTTTGAAGAGACACTTGCTCAGTCATCTTGAAAAGTATCCATGTAAGGAATGTGGAGCTACATTTAGTCACAAAACACTCCTCAACAATCACATATCAATCCATACGAAGGAATTTACAATCAAGTGTAAATACTGTACTAGAATGTTCAAAAATACAACATCCAGAaacaatcatcatcaaattgcACATAAAAATAAGGAGGAACTGCATTTTAAATGCAACAAGTGCAACGTATTCTTCGAGACAAAAGAGGACTTGAGAATCCATagctttattcattttaatggcGAAATAAAGACTTGCTTTCATTGTGATCAGATCTTTAAAACGACGagattattaaatattcatctaCAGAAACATTCgaataagaaatttcaatgcGAGTCATGCCtggaaaatttcacatttaaaagtGGCTTAACGAAGCACAAAAGATTAAATAGATGTAAAGGTCCACCAACGACTTTTGATGATGATCAGATGACAGAAGaggaaatcaataaaattgccAAGGAACAGCTAGAGTCCATATCATATAGTCGACAGAAAGAAGTACCTGAACCAGATTTGATTATTGACGATAAAAACGATGAAGATGTGCCTGAACGAGAAGTTGAAAGTTCGATAGAAAGTGATCATGAGGAACAGACTACGACAAATGTGCAGGAAGAAGAAGCACCACCATTAACAGTGAAACGATTTGGAAGAGCACATAAAACTTATATCTGTGATAATTGTGGCGATTCCATTAAATACAGAAAGAATTTAGAATTGCACATGAAGAATAATCATCTAAGGAAGAACTATAAATGCTCAAGCTGTTCGGAAGtctttaaaagtaaaataagcTATAAAGCCCATTCTCTGCAAGCGCACGGAATTAAACAAAGAATAGctgtcgaaattttcaaatgtaatGTCTGCGACAAGAAGTTTGACATAAAAAGCATCTATGAAGCACATAAATTGTCACATGATGATCTCCGTCCACAAGTCTGTAAAATATGTAATGCATCATTCAAAAGTATTGGAAACCTTAAAAGACATAATCTCATCCATATTGACgagagaaattatttatgtgaTGCATGCTCAAAATcctttaaaagtgaaaatgcaCTAAAGATTCACAAGAATTCTGTTCATGCTTCAGTGAAGGTTTACGTGAGCTGTCCACACTGTAAGATTATTCTACAAGAAAAGAACTTGAAGATTCACATCCATAATCAGCATACAGAAGAAGGTCAAAAGAAGCCATTTACATGCAGTGTCTGTAGCaagacatttaaaaatgaatttctccTCAAAAGACATTTCGAGCATCTCCATTTCAGTTCCAATCGAGGAATTATCTACAATTGTGAGCAGTGTGGACTGCCTTTTAATAGACAAAGAGATTTAAGGATACATTCATTTGAGCACTTTGAAGGAACAATTCATACTTGTTTTTGTGgtaaaaagtttaagaacAAACGACTACTTTTAATTCATTCGACTGTCCACGCTTCCGATACTAAGTTTCAATGCAATTTATGTGATGCTATTTTCAAGACGTCTGGTGGACGAAGAAAGCACATAGcaaaacatcataaaacagCATTAAATGTTGAGGATTTAGTGATAAAGTATGATGAAGTCACGGAGCATGTTTCtacattttaa
Protein Sequence: MKTTKDTHKHEGKTGKSKKSLQCEICKSILKSEYYLKKHKESRHPEHPRNYICDYDGKVFANKNYLRIHMERHQQEILTCNICMKAYNSKIILKRHLLSHLEKYPCKECGATFSHKTLLNNHISIHTKEFTIKCKYCTRMFKNTTSRNNHHQIAHKNKEELHFKCNKCNVFFETKEDLRIHSFIHFNGEIKTCFHCDQIFKTTRLLNIHLQKHSNKKFQCESCLENFTFKSGLTKHKRLNRCKGPPTTFDDDQMTEEEINKIAKEQLESISYSRQKEVPEPDLIIDDKNDEDVPEREVESSIESDHEEQTTTNVQEEEAPPLTVKRFGRAHKTYICDNCGDSIKYRKNLELHMKNNHLRKNYKCSSCSEVFKSKISYKAHSLQAHGIKQRIAVEIFKCNVCDKKFDIKSIYEAHKLSHDDLRPQVCKICNASFKSIGNLKRHNLIHIDERNYLCDACSKSFKSENALKIHKNSVHASVKVYVSCPHCKIILQEKNLKIHIHNQHTEEGQKKPFTCSVCSKTFKNEFLLKRHFEHLHFSSNRGIIYNCEQCGLPFNRQRDLRIHSFEHFEGTIHTCFCGKKFKNKRLLLIHSTVHASDTKFQCNLCDAIFKTSGGRRKHIAKHHKTALNVEDLVIKYDEVTEHVSTF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00321249; iTF_00319916;
90% Identity: iTF_00321249;
80% Identity: iTF_00321249;