Basic Information

Insect: Cerastis leucographa
Gene Symbol: Zfa
Assembly: GCA_963082945.1
Location: OY720384.1:15480358-15488882[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 23 0.011 1.2 10.9 1.6 3 23 582 603 581 603 0.96

2 23 0.23 26 6.7 0.3 1 22 990 1011 990 1011 0.95

3 23 8.4 9.5e+02 1.8 0.4 1 22 1053 1074 1053 1076 0.82

4 23 0.018 2.1 10.2 4.8 2 22 1086 1106 1085 1106 0.93

5 23 0.072 8.1 8.3 0.0 3 23 1115 1136 1113 1136 0.89

6 23 0.02 2.2 10.1 0.2 3 23 1157 1178 1155 1178 0.96

7 23 0.0037 0.42 12.4 2.5 1 23 1184 1207 1184 1207 0.95

8 23 0.14 16 7.4 0.0 1 23 1233 1256 1233 1256 0.90

9 23 0.0062 0.7 11.7 3.5 1 23 1261 1283 1261 1283 0.97

10 23 0.0097 1.1 11.1 0.2 1 23 1289 1312 1289 1312 0.95

11 23 0.0045 0.51 12.1 0.8 1 23 1325 1347 1325 1347 0.97

12 23 0.0002 0.023 16.4 1.8 1 23 1397 1420 1397 1420 0.97

13 23 0.00019 0.022 16.4 0.9 1 23 1480 1503 1480 1503 0.96

14 23 0.0027 0.3 12.8 2.1 2 23 1530 1552 1529 1552 0.95

15 23 0.044 5 9.0 0.1 2 23 1558 1580 1557 1580 0.94

16 23 0.011 1.3 10.9 0.2 1 21 1624 1644 1624 1645 0.95

17 23 0.00047 0.053 15.2 1.0 1 23 1655 1677 1655 1677 0.93

18 23 0.00013 0.014 17.0 0.3 2 23 1770 1792 1770 1792 0.93

19 23 4.4e-07 5e-05 24.7 1.4 3 23 1799 1819 1798 1819 0.98

20 23 0.025 2.8 9.8 0.3 1 23 1837 1859 1837 1860 0.95

21 23 0.21 23 6.9 0.0 1 23 1883 1905 1883 1905 0.97

22 23 0.031 3.5 9.5 0.6 1 23 1911 1934 1911 1934 0.95

23 23 0.00029 0.032 15.9 0.4 1 23 1942 1965 1942 1965 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	23	0.011	1.2	10.9	1.6	3	23	582	603	581	603	0.96
2	23	0.23	26	6.7	0.3	1	22	990	1011	990	1011	0.95
3	23	8.4	9.5e+02	1.8	0.4	1	22	1053	1074	1053	1076	0.82
4	23	0.018	2.1	10.2	4.8	2	22	1086	1106	1085	1106	0.93
5	23	0.072	8.1	8.3	0.0	3	23	1115	1136	1113	1136	0.89
6	23	0.02	2.2	10.1	0.2	3	23	1157	1178	1155	1178	0.96
7	23	0.0037	0.42	12.4	2.5	1	23	1184	1207	1184	1207	0.95
8	23	0.14	16	7.4	0.0	1	23	1233	1256	1233	1256	0.90
9	23	0.0062	0.7	11.7	3.5	1	23	1261	1283	1261	1283	0.97
10	23	0.0097	1.1	11.1	0.2	1	23	1289	1312	1289	1312	0.95
11	23	0.0045	0.51	12.1	0.8	1	23	1325	1347	1325	1347	0.97
12	23	0.0002	0.023	16.4	1.8	1	23	1397	1420	1397	1420	0.97
13	23	0.00019	0.022	16.4	0.9	1	23	1480	1503	1480	1503	0.96
14	23	0.0027	0.3	12.8	2.1	2	23	1530	1552	1529	1552	0.95
15	23	0.044	5	9.0	0.1	2	23	1558	1580	1557	1580	0.94
16	23	0.011	1.3	10.9	0.2	1	21	1624	1644	1624	1645	0.95
17	23	0.00047	0.053	15.2	1.0	1	23	1655	1677	1655	1677	0.93
18	23	0.00013	0.014	17.0	0.3	2	23	1770	1792	1770	1792	0.93
19	23	4.4e-07	5e-05	24.7	1.4	3	23	1799	1819	1798	1819	0.98
20	23	0.025	2.8	9.8	0.3	1	23	1837	1859	1837	1860	0.95
21	23	0.21	23	6.9	0.0	1	23	1883	1905	1883	1905	0.97
22	23	0.031	3.5	9.5	0.6	1	23	1911	1934	1911	1934	0.95
23	23	0.00029	0.032	15.9	0.4	1	23	1942	1965	1942	1965	0.96

Sequence Information

Coding Sequence: ATGAATGTGAACTATGATCGTGTTTGTAGACTGTGCTTGTCATCTCGAGGCGAATTACTGCCGATTTTTCCTACCACCAGTTCGGATGACTCGGAACCTCCCGTCCTCGCTCTGAAAATCAAGGATTGTGTGTCCGTACAGataaaCGAAAATGACGAACTGCCTACCAATGTCTGCAGGAAATGCATGGACAATGTCAATAACTggcatgtttttaaaaatgtatgtgaAAGGACACAAAACAAACTACTGTCTCTAAAAGATGGCAACCAACTAGAAGAGgtcaaaataaaaagtgaACCATTGTCTGATGAGGCTTATGATGATGGAGTGGTCATTGATGGCTCATATCCTGTCATTGAGAATGCTGGCTATTCAAACAAAGTGCAACCTGAAGGTCCCCCAATCTTGGCTTCATTGGGGCTCACACCAAGAAGTGATAAGAAATGTGTGGATCCACGAATGGATTGGCACCGGGTCCATGCAATTTTGGACATGGTTCAAGACAATGAGGTGATTGACTCTCTGCAGACAAGAGAAGAGTGTGATGTTTTGCAGCATTCTGACCATGACTCAGACACTGAAGCCGAACTCCAAACAGAAATTGATGATGGTTATGTTAATAGCAAAAGCGGATACatatgcaaaaataaacaagttaTGTCAAAAATTCCAAAACTATCGACTTCTGTAAATAATGCCAGAGTGAAAGAAGCTTTCAAACTCAGGAAACGTAAATCAGAAGTTCGTAAACATTGTTCACAACCTAAAAATGCGTGGCAGTTGTTATTCACTGATGACCTACTAGAGTTGATCGTTGCTTCCACTAATGGCAATATTGTGACAAATGGGAAAAGTTTCACGGAGTCAACGAGCGTCAGCGAAATTAAAACGCTTATCGGTATTCTGTATCTGCACGGCATAATGCGGCCGACACATCAGAATTGTAGTGACCTTTGGAACAGTGAATGTGGTGTTCCTTGCGTCAGAAAAATCATGAAATACGAAAGGTTCAAGTTCCTGCTTCAAAACATGAGCTTCGATAAAGACGACGACAACAGCATTATACAGTTTGACATAATGAAGCGTATGCGCAAAGTATTCGAAATCTTCGCCATGAATTGCAGAACATCTCACGAGATCGAGAATGTCGCAGTTATTGATGAGATCATCGTGCCAGTTTACGGACCTTGCCCATTTCGATACGAAATTGATAAGAAGCCGCTGAAGCGAGGCTTAAAGATGGTATTGCTAGTTGATTCATCAACATTCTATATGAGCAATTTAGACGTCATCACTGATCGTTACTTCGGCGCCGAAGAGATAACAAAAAAGTTGGTTCAGCATTTAGCTGGAACTGGCAGATCTATTGTTATGGACAGTTGGTTCACTTCTTCCTCATTGATGAATATCCTTAAAAATGAGTACCAGTTATATTCTATTGCAGCCTTGAACCCAAACAGTGATATGATTCCGCCACTATTCCTATCTCAGTACAGGAAATGTCGGACATTCATGTCTGGATTTATTGATCATGAAGTATCATTGACATCGTATGTCAATACTGAGGGGAAATCCGGTGCAGAGAGTGAAAACAATGAAGAAGACGAGGAAGAAATGAATGAGCCCGTACAAAATTTCCCAAAAATGCCTCATATGCCCGAGGTGTCCATCACGGTCATGAGGCCTACTGGTGAGACCCTGCACGCTCGCCAAGGTATTCACCAACTCGCTTCCAAACTGTGCCTCGTCTGCGGCCGCTCCTACAGGTACTCTCACAACGCACGCAGACATGAACTTACCTCTCACAGCTTCGACAGatatacaaacaaaattacTCCTAAAAAAACCCTCAATCATCTACAACCCAAACTGAGACCGAACCCATTCAACCCCAAAGCACGGATGATGCCGAATCCTATTAGTCATAAGATGCAGTTCATGAACAAGAACATGCCAACAAAAATAATGCCCATAAACAAAGTTATAACGCCACAGAAACCCATTCCAATAAAGACGTCGTCAAAGACACAAAATAATTTGCCTTATCCTCTACGCATTAAAGCactcaaagatttacaaattaaGAAAAAGGAGCCTCAGATTCTGAAGACTTTGTTAACCTCCAAACCTGAAGTTCTGGTCTCAGAGCCAGAAATTCTAAATTCTGGGCCTGAAAGTCCAGAAACATTGATATCTGAGCCTGAAATTGCATCTTTTCAAGTTGAAGCTATCCTCACGGAACCAGATGCCGATGCATACGATGATCAACAGCAAGGCGACGAAGAGGTCGATGAAGAAATGCAGAACAATCAAATTCAGAACTATGACACTGTTGATATGGACTCTGAGAATGAAATAGAGATTGCTCGTCAGCAAAGCATTGAGCATGATGGCGAGGAAAATGCTGATGGAGAAGAGATTATGGACCATGATGACGACAATAACATGGAAGGCGGTCAGAGCGATAACGAGAAAGATGCCAATGACGATACAGCTGATTGTCAAGAGaacatggaagaagaagatagtgTTGATATTAAACCTGAAGATCAAATGAAGGACGATGATGGCCTAGAAGAGGGAGAACACGAAGAAGTAGAAATTAATCATAACGAAAACGAGGAAGAAGACGATGATGACCTGCCAATGTCTCTAGCGCCTGTCGTCGAAATAAGTGAGGGATTGCAAGGCGACTCGATCAACAGCGAAGTCATTGAGGAAGACGAGGACGAAACTGTCGACGAAACTGTCGACCCCAATGACACCATTGTAGAGGAAGAACCGGTTAAAGAACTTGACCCTGACAAAACATATGTTACGAAAACCCAAAGAGACTTCATCCAAAAATACCGCGATATCATTCAGCAAATCAACACGAAGCGTTGTTTATGTTGTGATCGAGAACATCCGCGCAGAAAAGCTGTTATACAACACTTACAGAAAAACGGACACAAGGTACCAAAACACACATGCTACAATTGTGTCATCACGTTCGGACATATTGGCGCACTGCTCAGCCATATGAGGTCGAACTCTTGCACCAATTTGTGGaaaattatttacaatgaaaatgGAATTACTGACGACTTGGTTCTCGAAGATGAGCCGAAAGAGGTGAAGGTTGCTTACAAAGATATTTTCAATGCCAGGTCATACGCTTGCAAACTCTGCCCAGCTAAATTCCAACTCAAACAGTTTATAATGAAACATGTTTTGGATACCCATGAGGATGGACAGTCAAGGGTGCCACTCTGTTGTGTCCACTGCCGTTCTAGATTCAAAGATAAGAGTTTACTAAAGAAACACATTCGTAAAGGTGATTGTACAGTTTATATTGCTTGCGATTTGTGCCCAGAAACATTCAAGAACATGCAAGACTTCAACGACCATGCGCTAGCCATCCACGCTGGCAGTTTCGATCAGTCGGATAATCCGAGCAAATGTGTTGACGGTCGACCGACAGACTGTCCTCTGTGTGGAAAGAAAAACAGCAGCTATCCGAATTTAGTGAAACATTTGAAAATTATACATGCGGAGGAAAAACCTCACTACTGCCAGCATTGCGACGCGAAATACGAACAAGCTACTGATCTAAACAAACACATTTACATGGAGCATTCTGACAGAACACTAGGCATGCCTCCTGCAGAACCGGATATGTCTATAGTGAAGGAGGAAGCAGAGGAGTACCACTACTCGTGTACGGAATGTAATGCTATATTCGAAACTGTTGATGCGTGGACTGATCACCAAGTCGCTGAACACAACCAGGTGGCCCACCACTGTGACCAGTGTGATAAGAAATTCCTTCGTCCTTCAGAGCTTGCAGAGCACAAGAATACTCATTTGAGGGTTAAGTTTTATCCTTGCAGTGTATGTCCCAACTCTTACAGCACTCCACAGAAACTGTCTGAGCATGTGCAACAGTCACATCCAGGAATTGGCGCTGCCGCGGCGGCCGAGACGGAATTCTTCTGCGACATCTGTATCAGAGCATTCAAGAGTCGCCAAGCTTACTCAAATCATATGCGTATTCacgctaaagtacctactaCAAACAGGAAACCGACTCCAATCAAAGAGGGATTCGCGCCTCAAATCATCGGGAAACCCATCAAGCAGTATCCAATGGTTCAACCAGGTTTTGTATCATTTAAACCTAATTACAACATCCCTAACGCTCCATATTCTTGTGACATTTGTGGTAAAGGATTcatgcataagaaaaatatatGGAAACACAAGAAAGTGTTGCATGCTGATATTTTAGTCGATAGACATGATAGTGAAGAGAACACTATGCAAGCGTCTACGGAAGAGGAGGAATTCAATCCTGATGAGAACGGTGCCATTCTCTCGACGCCACAATTTGATAGTTTTAACTTTACGAACTTCCCGAACAATGCTCAACAATCAACACCAGAAGCAATGCCATATTCGTGTGAATTATGTGGCAAACGGTTCCCGCTTAGGACCAGTTTATGGAAACACAAGCGCGCAAAACACGGAATTGTAAACCCTAGCACTAGCGGTAACAACGAAACATCCACGCCGTCCGCTAGCGGGGAAAGCAGTAGTCGATCTAGCTGCACTATATGCAGAATCACATTTTCAGATAAGAAATCTTACTATCGCCATAGAAAGAATGTCCACAAATCTACCGTTCAAATGTGCAAAATATGTGGCAAACCGCTAAGTTCAACTTTGGAATTATATGAGCACTTGAAAGCTGCCCACGCAAGGGAATTACTGGGTTATAATGCTAACCAAGGCTCCAGTAAATCACAAGATATGTCACAAGAGATGGAACCGGATTATGAGAATGATCAAGAGTCCATCGACCCCAGCGTTGATTACCAAGCGCGGTACCCGTGCGATACTTGTGGCAAACAATTTGTTGGTTTGCTAGCTTTGCAAAACCACCAGTGCATCAATCAGATAGCTTCACAGCCACAGACTTTTGACTGCGAGATTTGTCACAAGAGTTACACTTCAATATCTGCGCTAAAAAGCCATCGTGGGTGGCATTTACGTTCGCCCGATGGAAAAGCAGCCGCCAACAATTCTGGCCTGTGGATGCCTCAGCACAAAGTTACTAGCAAGGTAAGCAAACATGAGGTCGTGGACGCGTCACAACTGGCTAAGGTCACACATACCCCCACTCCCCCTCCTGTCTCTGCTACCGCGGCGAAAAGAAGACTACCACCAGAGGTTGAAGTGACAGTCGTAAATCCGAACAAAAAACTACGCTCAGACGACTCGGTCGACTTGGATATGCAAAGTTCTGGTACCATCGAGGATAGGTACTGTACGATTTGCGATAAGGAATTTACAAAACGAGCGGCGTACCAGCGCCACATGGACGAGGTACATCAACCGAACTCTGTGTTTTGCCCGGTCTGTGATAAGAGTTTTACAAGGAAGTCCACATTGCTCATTCACATGAAGAAACATTACGAGAGCGGTGAGGGCAGTTCCTCTGCTACAGGTCAAGGAGACGATGATTACTCCTGTGATTTGTGTGGAGCTCAGTATGACAATGATCAGGCATTGAGGGCGCACCGAGCGCGGCACCACGGAGAAGATGAAGAGTCGGCTGAAGAGAGTGACGACGGAAATATTCCTATTGCTCCTCCCGGTGAATTCACATGTGCGCAATGTGGCGATGGCGTCGCTACTCCCAGGGACCTCATCGCCCATCGCACAATGCACGCTACTCCCACCAAATTCTTCTGTAACATATGCAAAGTGTACTTCGCTCGGGCGCTCGACCTCTCGTCGCACACTCGGGCGCGACACGCTGACAACGAAAAGGTATTCTTCCCGTGTGCCATGTGTGACAGGTTTTACATGAACAAGAAGAGCTTACAGCGGCACATTGAGATGGCTCACTGA
Protein Sequence: MNVNYDRVCRLCLSSRGELLPIFPTTSSDDSEPPVLALKIKDCVSVQINENDELPTNVCRKCMDNVNNWHVFKNVCERTQNKLLSLKDGNQLEEVKIKSEPLSDEAYDDGVVIDGSYPVIENAGYSNKVQPEGPPILASLGLTPRSDKKCVDPRMDWHRVHAILDMVQDNEVIDSLQTREECDVLQHSDHDSDTEAELQTEIDDGYVNSKSGYICKNKQVMSKIPKLSTSVNNARVKEAFKLRKRKSEVRKHCSQPKNAWQLLFTDDLLELIVASTNGNIVTNGKSFTESTSVSEIKTLIGILYLHGIMRPTHQNCSDLWNSECGVPCVRKIMKYERFKFLLQNMSFDKDDDNSIIQFDIMKRMRKVFEIFAMNCRTSHEIENVAVIDEIIVPVYGPCPFRYEIDKKPLKRGLKMVLLVDSSTFYMSNLDVITDRYFGAEEITKKLVQHLAGTGRSIVMDSWFTSSSLMNILKNEYQLYSIAALNPNSDMIPPLFLSQYRKCRTFMSGFIDHEVSLTSYVNTEGKSGAESENNEEDEEEMNEPVQNFPKMPHMPEVSITVMRPTGETLHARQGIHQLASKLCLVCGRSYRYSHNARRHELTSHSFDRYTNKITPKKTLNHLQPKLRPNPFNPKARMMPNPISHKMQFMNKNMPTKIMPINKVITPQKPIPIKTSSKTQNNLPYPLRIKALKDLQIKKKEPQILKTLLTSKPEVLVSEPEILNSGPESPETLISEPEIASFQVEAILTEPDADAYDDQQQGDEEVDEEMQNNQIQNYDTVDMDSENEIEIARQQSIEHDGEENADGEEIMDHDDDNNMEGGQSDNEKDANDDTADCQENMEEEDSVDIKPEDQMKDDDGLEEGEHEEVEINHNENEEEDDDDLPMSLAPVVEISEGLQGDSINSEVIEEDEDETVDETVDPNDTIVEEEPVKELDPDKTYVTKTQRDFIQKYRDIIQQINTKRCLCCDREHPRRKAVIQHLQKNGHKVPKHTCYNCVITFGHIGALLSHMRSNSCTNLWKIIYNENGITDDLVLEDEPKEVKVAYKDIFNARSYACKLCPAKFQLKQFIMKHVLDTHEDGQSRVPLCCVHCRSRFKDKSLLKKHIRKGDCTVYIACDLCPETFKNMQDFNDHALAIHAGSFDQSDNPSKCVDGRPTDCPLCGKKNSSYPNLVKHLKIIHAEEKPHYCQHCDAKYEQATDLNKHIYMEHSDRTLGMPPAEPDMSIVKEEAEEYHYSCTECNAIFETVDAWTDHQVAEHNQVAHHCDQCDKKFLRPSELAEHKNTHLRVKFYPCSVCPNSYSTPQKLSEHVQQSHPGIGAAAAAETEFFCDICIRAFKSRQAYSNHMRIHAKVPTTNRKPTPIKEGFAPQIIGKPIKQYPMVQPGFVSFKPNYNIPNAPYSCDICGKGFMHKKNIWKHKKVLHADILVDRHDSEENTMQASTEEEEFNPDENGAILSTPQFDSFNFTNFPNNAQQSTPEAMPYSCELCGKRFPLRTSLWKHKRAKHGIVNPSTSGNNETSTPSASGESSSRSSCTICRITFSDKKSYYRHRKNVHKSTVQMCKICGKPLSSTLELYEHLKAAHARELLGYNANQGSSKSQDMSQEMEPDYENDQESIDPSVDYQARYPCDTCGKQFVGLLALQNHQCINQIASQPQTFDCEICHKSYTSISALKSHRGWHLRSPDGKAAANNSGLWMPQHKVTSKVSKHEVVDASQLAKVTHTPTPPPVSATAAKRRLPPEVEVTVVNPNKKLRSDDSVDLDMQSSGTIEDRYCTICDKEFTKRAAYQRHMDEVHQPNSVFCPVCDKSFTRKSTLLIHMKKHYESGEGSSSATGQGDDDYSCDLCGAQYDNDQALRAHRARHHGEDEESAEESDDGNIPIAPPGEFTCAQCGDGVATPRDLIAHRTMHATPTKFFCNICKVYFARALDLSSHTRARHADNEKVFFPCAMCDRFYMNKKSLQRHIEMAH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00017541;
90% Identity: iTF_00758469;
80% Identity: -