Basic Information

Gene Symbol
-
Assembly
GCA_963564715.1
Location
OY751353.1:1144016-1145758[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 15 0.00033 0.038 15.8 3.2 1 23 9 31 9 31 0.96
2 15 0.0063 0.74 11.7 0.1 2 23 59 81 58 81 0.91
3 15 0.0069 0.81 11.6 2.0 1 23 101 124 101 124 0.96
4 15 5.3e-05 0.0062 18.3 0.4 1 23 129 152 129 152 0.96
5 15 0.001 0.12 14.2 0.8 1 23 157 180 157 180 0.97
6 15 0.00059 0.069 15.0 0.5 2 23 183 205 183 205 0.95
7 15 0.0033 0.38 12.6 1.0 2 21 213 232 212 233 0.94
8 15 0.0015 0.17 13.7 2.0 1 23 285 308 285 308 0.95
9 15 4.1 4.8e+02 2.9 0.0 2 23 381 404 380 404 0.86
10 15 9.8e-06 0.0012 20.6 0.2 3 23 411 432 410 432 0.94
11 15 0.0032 0.38 12.7 2.9 2 23 437 459 436 459 0.94
12 15 0.00029 0.034 15.9 5.1 1 23 464 487 464 487 0.96
13 15 2.1e-05 0.0024 19.6 4.8 1 23 491 514 491 514 0.97
14 15 0.00014 0.016 16.9 0.3 2 23 521 542 520 542 0.96
15 15 1.3e-05 0.0015 20.2 1.4 1 23 548 570 548 570 0.97

Sequence Information

Coding Sequence
ATGCCATTCAAATGGCGAGGCAAATATCTTTGCTTCTATTGCGGCAAGAACTACACCGAATACTCAGAGTTTAAAAAGCATACGAAATCTCACGGTATATGCAACACTAAAGATTACTCGTTAAAATTAATCAAAGGAAATAATATCGAAATTAAAATCGATGTTTCTGAAATTTCTTGTGATATTTGTAACGAATCTTTCAATCGATATGAGGAAATAATCGATCATTTGATTGGCAAGCATAAAttagaatacaataaaaatattgatattccaTTCCAAAAGTACCGACTAGCTGATTTTAAGTGCCTACATTGCGAGGAGCAGTTTTCTTACTTCGGATATTTAGTAAATCACGTGAATAACATGCATCCACAGAATTGCTTTATTTGTAACGATTGTGGGGGACGATTCAATAAGAAGAGAGATTTAGCGATTCACATAAGGAACTATCATCGCGTGGGAGGCTATCCGTGTACCATGTGCTTGCAGAGTTTTGATACTCTGCAGGCCATGCGGAGACATCAAAACAGTACGCATTTTAGACAGTGCAAGAGTTGCGGTTCTAGATTCGCGTCTCTCTCGCTTTTGCAAAAACATTTACAAGCAGAGCATCGCCACGATGAAGGTAACATGAAGTGCAGCTACTGCTCTAAAGAGTTCCATTCCTCCATAGGTCTAAGGCAGCATATAAGCAAATGCAAAGTGAAAATAATTTCTCAAGCCATACCTGAGTCTTTTTCTGAAGATAGCATTGAGCCTAGAAAGAAGCAAAACATACTACAGATTCGTCAAAATATACAATGTGTGTTAAACATGTCCACGGCTATTCCCTTCAAATTTTTTTCCAAATATTCTTGCTTTTATTGCTCGAAGAAGTTcttcgattttgatgaattacGTGAACATACGACTGTTGAACATCCCGTTTGTGATTTGAAACAGAAATGTATGAAAAAGTGCAAAGGCGAAAGGATTACCGTTAAAATTGATATTGCGGCTTTGGCTTGTAAAGTCTGTTGTCTTCCAATGCCCGATTTGGAATCTTTGATAAACCATTTAATAGCTGTGCATAAAGCGAATTATGATAAGTCTATCACTGGATGCCTCGAACCGTTTAAGATCATTAAAGATAATATGCCTTGTCCAATATGTCCGGATAAAATCTTTAGATACTTTGGAATCTTGTTACGTCATGTGAACGCAGAGCACAGTAACAATAATAGGATTTGTGATTTCTGTGGCAGAAGCTTCCGTAACGCGGCCAATTTGAACGTTCATATAACGTACTCTCACACTGGTTCTTGTGAATGTGATGTCTGCGGCGTCAAATATAAAAACCAGTGGTGTCTAGCCAGGCATAGGGCTAAAACACATAACGCGAAAGACCACAAATGTCCCAAATGCCCTGAGACTTTCAATTCGCAATACCATAAGCAGAAGCATTTGATTAAAATGCACAATATTGGTCACAAATGTGATTATTGCGATAAAATGTTCACAAGAAACTCGTTCATGAAAGACCACGTAAGACGGACGCATTTGAAAGAGAAAAATGTtccttgttctatttgcaacgAGAAGTTCTTCGATAATTACCTTTTAAGGATGCATATGGTTAAGCATGAGGGAGATAGAAAATTCTGCTGCACTGTATGCGGCAAGGCCTTTTTGAGAAGGAGTAATTTGGCTTCCCACATGGAGATGCATAAAAAGTATGGACATGTGCAGTTACAAATTTGA
Protein Sequence
MPFKWRGKYLCFYCGKNYTEYSEFKKHTKSHGICNTKDYSLKLIKGNNIEIKIDVSEISCDICNESFNRYEEIIDHLIGKHKLEYNKNIDIPFQKYRLADFKCLHCEEQFSYFGYLVNHVNNMHPQNCFICNDCGGRFNKKRDLAIHIRNYHRVGGYPCTMCLQSFDTLQAMRRHQNSTHFRQCKSCGSRFASLSLLQKHLQAEHRHDEGNMKCSYCSKEFHSSIGLRQHISKCKVKIISQAIPESFSEDSIEPRKKQNILQIRQNIQCVLNMSTAIPFKFFSKYSCFYCSKKFFDFDELREHTTVEHPVCDLKQKCMKKCKGERITVKIDIAALACKVCCLPMPDLESLINHLIAVHKANYDKSITGCLEPFKIIKDNMPCPICPDKIFRYFGILLRHVNAEHSNNNRICDFCGRSFRNAANLNVHITYSHTGSCECDVCGVKYKNQWCLARHRAKTHNAKDHKCPKCPETFNSQYHKQKHLIKMHNIGHKCDYCDKMFTRNSFMKDHVRRTHLKEKNVPCSICNEKFFDNYLLRMHMVKHEGDRKFCCTVCGKAFLRRSNLASHMEMHKKYGHVQLQI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00869876;
90% Identity
iTF_00636748;
80% Identity
iTF_00282645;