Basic Information

Insect: Camponotus fellah
Gene Symbol: slp2
Assembly: GCA_030586385.1
Location: JAPIVC010000941.1:1334624-1335862[+]

Transcription Factor Domain

TF Family: Fork_head
Domain: Fork_head domain
PFAM: PF00250
TF Group: Helix-turn-helix
Description: The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 5.6e-43 1.7e-39 135.3 0.1 1 87 103 188 103 189 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	5.6e-43	1.7e-39	135.3	0.1	1	87	103	188	103	189	0.97

Sequence Information

Coding Sequence: ATGGTGAATATGGAGAGTTCAGGCGAGCAGCACACCGTGACAGCTTCGCCGCCGCCACGGGCTGCCCTGAAGAGCAACTTCAGTATCCGCAGCATCTTACCCGAGGCTTGCGGCGGGACCCCCGCGCCGTCGGTCAGCCATTCGGATTCTTCCGATGCCGGTCACGTTGACGATAGCGACAGCGACCTCGATGTTACCGGTAATGGCATGGAAACGCCGCCCTTGGATTGCTCTACGAATGCAACGTCCGTCAGCCCGACGAGCCAAAAAGACTCCAAGGAGCAGCCGGAGGACAAGAAGAAGGCGGAGAAACCACCGTACAGTTATAACGCGTTAATCATGATGGCCATTCGGCAGAGCCCCGATAAACGGCTTACCTTGAACGGCATCTACGAATACATAATGCGTCACTTTCCCTATTACGAGAATAACAAGCAGGGCTGGCAGAATTCCATTCGACATAATTTGTCGCTCAACAAATGTTTCGTCAAAGTGCCTCGTCATTACGACGATCCGGGCAAGGGGAACTATTGGATGCTGGATCCGAGTTCCGAGGATGTGTTCATCGGGGGTACCACAGGGAAACTTCGACGCAGGACTACGGCAGCCTCCAGGTCTCGGCTAGCAGCCTTCAAGAGGAGCGTAGTGCTCGGCGGACTTTACCCACATTATCCGCCACCAGGATGGCCAGCATCGCTCTACACCTTACCGTGTCTCCATCGCGCCGTTTCGTATCCCGTGACCACTTCTTATACAACTCCGGCCGGATATCCGGCCAGTCTGTTGCCTGGAGCGGCAACCACATCGGCTACAGGCTTGCCTTGTAAGCCGCAGCCTCTTCCAGCGACGGCGGCACCTCCGGCGGCTCACGGAGCGTTCTCCGTGGAAAGGCTACTGCAGGCACCTACGAGTTATCCTCCCGGTATCGCGACATCCGGAATCCCGCCACCAGGGCATCCTTATCAGGACTTTTATACGACTTTAAGATCTATCGCGGCGCATCAGCAACATCAGGCAGCGGTGTTCAATCAGCAACCTAGGTATCATCTCAGTCAAGCGCCAGTTTTAAGCCAGCCTGCCTCTAGCACGGCTTCGCCCGGAAGTAGTCCGGAGCCGATGGATCCGCATTCGCCACCGGTTACCATCTGTAACTCTGTCCAGCCGCCGAGACCGCTTCCTCACAATCCGCCGCAGCTTCTTCTAAAGCCCATCACGGTCCTCACAGGCCGACAAAGCTGA
Protein Sequence: MVNMESSGEQHTVTASPPPRAALKSNFSIRSILPEACGGTPAPSVSHSDSSDAGHVDDSDSDLDVTGNGMETPPLDCSTNATSVSPTSQKDSKEQPEDKKKAEKPPYSYNALIMMAIRQSPDKRLTLNGIYEYIMRHFPYYENNKQGWQNSIRHNLSLNKCFVKVPRHYDDPGKGNYWMLDPSSEDVFIGGTTGKLRRRTTAASRSRLAAFKRSVVLGGLYPHYPPPGWPASLYTLPCLHRAVSYPVTTSYTTPAGYPASLLPGAATTSATGLPCKPQPLPATAAPPAAHGAFSVERLLQAPTSYPPGIATSGIPPPGHPYQDFYTTLRSIAAHQQHQAAVFNQQPRYHLSQAPVLSQPASSTASPGSSPEPMDPHSPPVTICNSVQPPRPLPHNPPQLLLKPITVLTGRQS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00633434;
90% Identity: iTF_00264815; iTF_00109636; iTF_01245029; iTF_00280460; iTF_00729100; iTF_00730541; iTF_00279776; iTF_00867201; iTF_01254604; iTF_00868575; iTF_00867946; iTF_00729874; iTF_01077280;
80% Identity: -