Basic Information

Insect: Bruchidius siliquastri
Gene Symbol: Hr39
Assembly: GCA_949316355.1
Location: OX438531.1:39921772-39928314[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 2 2e+04 -6.9 7.0 71 146 195 267 44 319 0.59

2 4 6.8e-09 6.8e-05 22.6 0.0 1 30 444 473 444 510 0.84

3 4 0.036 3.6e+02 0.5 0.0 86 119 500 531 470 545 0.64

4 4 8.9e-73 9e-69 233.0 0.0 202 408 571 772 491 772 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	2	2e+04	-6.9	7.0	71	146	195	267	44	319	0.59
2	4	6.8e-09	6.8e-05	22.6	0.0	1	30	444	473	444	510	0.84
3	4	0.036	3.6e+02	0.5	0.0	86	119	500	531	470	545	0.64
4	4	8.9e-73	9e-69	233.0	0.0	202	408	571	772	491	772	0.87

Sequence Information

Coding Sequence: ATGATCCCTGAGGCACTTAGTGAGCGGCGCGCCAAACCGTCCGGCCCCGGGCCGTGTCATGCCCGCGCGGCCAGCCGCGACCGGCGCGAGCTGATAGTCGTCACCGTGGACGGTGGAGGAGGCATGGCGGCGGAGATGTCCGCACAGGCGACGGCCGCGTCCGTCGCGACGCCCGCCACCGCCCCCGGCACCGTCGCCCCCAACCACCATCATCCCCATCACGTCTCCGTGACGGCCGTCAACGTCGACGAGCCGCCCCAGCGGGCGCGCAGTGCGCCGCATCCAGCCGCATCCCATCTCATGCACAATGGCACCCCAGACATATTAGACAGCTCCGATGCAGAAGTAGCCAGGATAGACTTCCACTCTGTGAACATGCGGTCGAAAAAGAAAAGTGACGACCTGCCCAGGCCGATGAGTTGGGAAGGAGAACTCTCCGATGGTGAGAGGGATGTAATGTGCGTGGACGAAGAGAATTCGGAGCCGGTGCCTGAGAATCTGTCACTGCCGCAATCGAAACAGTCCGTTTCCGATCCTAAAGAGAGCCCCGTCCTTCTGATCAAACAGCCTCCCATCGGTAACTATTCGTTGCACAGCACGCCCAGCAATTCTCCCGTACTTAGCCAACGACACCCCATCACAGGTGTGTCAATCATCAGTCACAAGGATCTTATGCACAAGTCCCTGAACGGTGGCGGCGGCGTGCCGCCCACCCCCAGCCCCGATTCGGCCGTCCATTCGGCGTACAGCGTGTTCAGCTCGCCGACGCACAGTCCGCTGCAGCAGCGCCATCTGGCGCTGACACCCAGCCTTAGCCGAAACAACAGCGACGCCTCGCGGTCCAGCTGCTGCAGCTTCGGCAGCGTTTCCGCCGTCTCCGTGTCGCCGACACAGCAATTCTCACCCACGCACAGCCCCATACAGGGTCGTCATATACACAACATTCACAGTAGTCCTCTGCATCACAACATTCTGTATCGTAGTCTTCAAGAGGATCCTACTATTCAATACTCAGCCGATCAAGAAACACTAGATGAACCACTTGAAGATAAAGCTGGACTCTTACACAGTTCCTTGCCTGCACAACCTGGCATTTCTAGGCAACAGTTGATAAACAGTCCGTGTCCAATATGCGGCGATAAAATTTCTGGATTCCATTACGGAATATTCAGTTGCGAGTCATGTAAAGGATTTTTCAAGAGGACTGTTCAAAACAGGAAGAATTATTTATGCCTTAGAGGAGCGCAGTGTCCTGTTACGGTGGCGACGCGGAAGAAATGTCCTGCTTGCCGATTCGATAAGTGTCTTCAATGTGGGATGAAGCTAGAAGCGATTCGCGAGGACCGCACTCGGGGCGGCCGATCCACCTACCAATGCTCGTATTCGCTGCCGCCGTCACTGGCCGGACAGCAACAGCACCACGGCGATTCCCGGTTAACTCCCGACGGGCAGCCAGTGATCAAGACGGAGCCGCAAGATGGCGCCGCATCCTCCGCAGCCGGCTCCAGGAGGGTATCGCCCGGGTCCAAGGGTGTCCCGCCGTTATTGCAAGAGATAATGGACGTGGAGCACTTGTGGCACTACAGCGAATCGGAGTTGAGCAAGTTGAACAGCGAGGGGAGGTTGAGCAGGGAAGGCGGGGGCAGCGGGGCGGGCGGCGTGCATAACCTGTCGACACACCCTCTGCTCGCTGGCACCGCGCTCGCTGGCTCAACCGACACCAACCCGGACTTCGTCGCGAACCTGTGCAATATCGCAGATCATCGACTCTACAAGATCGTCAAGTGGTGCAAGAGTTTGccacttttcaaaaatatatcgATCGACGATCAAATTTGCCTGTTGATCAACTCTTGGTGCGAATTGTTGCTGTTTTCCTGTTGTTTCCGTTCCATGTCGACGCCCGGTGAGATTCGCGTGTCTTTAGGAAAAAGCATCAGCTTGGCGCAAGCCCGAGAAATGGGCGTCCAAGCGTGCATCGAACGAATGCTCAATTTCACCGAGCAGTTGAGGCGGCTCAGAGTGGATAGGTACGAGTATATCGCGATGAAGGTTATACTGCTACTCACCTCAGATACGTCCGAACTTCGTGATGCGGAAAAGGTGCGAGTGTCACAGGAAAAAGCTTTGAAAGCACTCCAAGATTACACTTTATCTCATTATCCAGACAGTCCATCAAAATTTGGCGAACTGTTGCTTCGCATTCCAGAACTGCAGAGAACTTGCCAGGTTGGAAAAGAAATGCTGACCATCAAATCGAAGGATGGCGACGGACCCAGCTTCAACCTCTTGATGGAACTCCTCAGAGGGGATCACTGA
Protein Sequence: MIPEALSERRAKPSGPGPCHARAASRDRRELIVVTVDGGGGMAAEMSAQATAASVATPATAPGTVAPNHHHPHHVSVTAVNVDEPPQRARSAPHPAASHLMHNGTPDILDSSDAEVARIDFHSVNMRSKKKSDDLPRPMSWEGELSDGERDVMCVDEENSEPVPENLSLPQSKQSVSDPKESPVLLIKQPPIGNYSLHSTPSNSPVLSQRHPITGVSIISHKDLMHKSLNGGGGVPPTPSPDSAVHSAYSVFSSPTHSPLQQRHLALTPSLSRNNSDASRSSCCSFGSVSAVSVSPTQQFSPTHSPIQGRHIHNIHSSPLHHNILYRSLQEDPTIQYSADQETLDEPLEDKAGLLHSSLPAQPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYLCLRGAQCPVTVATRKKCPACRFDKCLQCGMKLEAIREDRTRGGRSTYQCSYSLPPSLAGQQQHHGDSRLTPDGQPVIKTEPQDGAASSAAGSRRVSPGSKGVPPLLQEIMDVEHLWHYSESELSKLNSEGRLSREGGGSGAGGVHNLSTHPLLAGTALAGSTDTNPDFVANLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSISLAQAREMGVQACIERMLNFTEQLRRLRVDRYEYIAMKVILLLTSDTSELRDAEKVRVSQEKALKALQDYTLSHYPDSPSKFGELLLRIPELQRTCQVGKEMLTIKSKDGDGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00260641;
90% Identity: iTF_00260641;
80% Identity: iTF_00249000;