Basic Information

Gene Symbol
Trl
Assembly
GCA_964007535.1
Location
OZ023328.1:41774487-41776580[+]

Transcription Factor Domain

TF Family
zf-GAGA
Domain
zf-GAGA domain
PFAM
PF09237
TF Group
Zinc-Coordinating Group
Description
Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 1.4e-17 1.8e-13 51.5 0.1 20 50 12 42 6 44 0.93
2 3 0.98 1.3e+04 -2.5 0.7 13 24 54 65 51 70 0.70
3 3 3 3.9e+04 -5.6 6.0 10 26 85 102 77 106 0.64

Sequence Information

Coding Sequence
ATGGAATgttatcaagACTCGAAGCTGTCCAACAATTCCGATCAACCCGTCACCTGTCCGATTTGTAATATTACCCTGCGTCAGTCTCGAAACCTACGGCGCCATCTTGAACTCCTCCATTTTGGGGCTGGCCAATCAAAACTCAAAATCAAGTCGTCTCGAAAGAAACGTTCGCGGAAGGAATCGACGACAACAGTCACCTCTCAGCCTTCTCCGTCTCACTCTGTACCTTCTCAATCGTGTACACCTCAACCGTCGACTCCTCAACCATCGACTTCCCAGTCTTCTACACCTCAGCCGTCTACCTCTCACTCCTCTACTCCTCAACCGTCTATCTCTCACTCTGGACTCTCTCATACGGTACCTGCTTTCCCTCAGCATGCTCCACCAATTTCAGGATACCAGAATCATCCAAATTCAGCATTACCAGAATTTCCCGGTCTCTCTAACCTCACACCTTTGGTCCCCATGTCTGTGAATCATCTGTCACATGGTATGATGGGACACCCACAGATGTCATCACAGTACAGAGGGCTACCGCCTATGGTTGCGCCGCACGACGGACTGTACAGACACCACACTGAGCCATATGAGCACTTCAGCCAGACAAGTAGATATCGAGTTCCATAA
Protein Sequence
MECYQDSKLSNNSDQPVTCPICNITLRQSRNLRRHLELLHFGAGQSKLKIKSSRKKRSRKESTTTVTSQPSPSHSVPSQSCTPQPSTPQPSTSQSSTPQPSTSHSSTPQPSISHSGLSHTVPAFPQHAPPISGYQNHPNSALPEFPGLSNLTPLVPMSVNHLSHGMMGHPQMSSQYRGLPPMVAPHDGLYRHHTEPYEHFSQTSRYRVP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00242815;
90% Identity
iTF_00242815;
80% Identity
-