Basic Information

Insect: Brachynemurus nebulosus
Gene Symbol: -
Assembly: GCA_035578155.1
Location: JAPWDM010000001.1:50225735-50227512[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 3e-07 1.6e-05 26.4 5.2 1 23 191 213 191 213 0.98

2 12 1e-05 0.00057 21.6 0.1 1 23 219 241 219 241 0.98

3 12 7.2e-05 0.0039 18.9 3.7 2 23 261 282 260 282 0.96

4 12 1.4e-05 0.00076 21.2 0.7 2 23 291 312 290 312 0.97

5 12 0.00023 0.013 17.3 0.3 1 23 318 340 318 340 0.97

6 12 2e-07 1.1e-05 27.0 1.1 1 23 346 368 346 368 0.98

7 12 8.8e-05 0.0048 18.7 0.7 1 23 374 396 374 396 0.94

8 12 0.00054 0.03 16.2 0.4 3 23 404 424 402 424 0.96

9 12 2.5e-06 0.00014 23.5 2.8 1 23 430 452 430 452 0.98

10 12 0.00033 0.018 16.9 1.8 1 23 458 480 458 480 0.99

11 12 7.2e-06 0.00039 22.1 0.9 1 23 486 508 486 508 0.98

12 12 2.5e-06 0.00014 23.5 0.3 1 23 514 536 514 536 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	3e-07	1.6e-05	26.4	5.2	1	23	191	213	191	213	0.98
2	12	1e-05	0.00057	21.6	0.1	1	23	219	241	219	241	0.98
3	12	7.2e-05	0.0039	18.9	3.7	2	23	261	282	260	282	0.96
4	12	1.4e-05	0.00076	21.2	0.7	2	23	291	312	290	312	0.97
5	12	0.00023	0.013	17.3	0.3	1	23	318	340	318	340	0.97
6	12	2e-07	1.1e-05	27.0	1.1	1	23	346	368	346	368	0.98
7	12	8.8e-05	0.0048	18.7	0.7	1	23	374	396	374	396	0.94
8	12	0.00054	0.03	16.2	0.4	3	23	404	424	402	424	0.96
9	12	2.5e-06	0.00014	23.5	2.8	1	23	430	452	430	452	0.98
10	12	0.00033	0.018	16.9	1.8	1	23	458	480	458	480	0.99
11	12	7.2e-06	0.00039	22.1	0.9	1	23	486	508	486	508	0.98
12	12	2.5e-06	0.00014	23.5	0.3	1	23	514	536	514	536	0.98

Sequence Information

Coding Sequence: ATGGAGGATAAACCAGAAATTGCGTTAGATAAAATTTGTAGAGCTTGTATGGCTGAAAATGTTGAAATGCGATCAATTTTTGTCCCAGATGAAAATTTAGATACAAACATACATTTGTCGGAAATGATAATGGCGTATGCTGCCGTTCAGATTACACTTGGTGATGGTTTACCTGAACAAATATGTTTGGATTGTGCTAGTCAAGTTAGCAAGACATATTCGTTTAAACAGCAGTGTGAGAGATCGGATGCTGCTCTGCGTGAAAAACTTGGTTTAGAAAAGCTTGTGCTACCGAAAGAAGAAGTTGTACACTCACTAAATCCGACGTCAGTATTTGATTCGGAAGAAATTGTTATAAAACcagaaattaaagaaattaacgGCGATGACGATGATGATGATTATCCTGAAATGCATGCTGAAATCACTGCGGCCCCAATCGGATCAGAAGACGAATTACTTGGTGATGAAGATATGCAAAATGCTATGAACAATATTAAACAGGAGGTTGAAAATGAGAAAGAAGCTTTGGAAAAATTCAACGATATATCTTATGATATTAGAAAAATTCATACATGTCCGATTTGTAAGAAGTCATTTAATCGTAACAGTCATTTAAGTCGCCACTTAAGAGTGCACACTGCTGAAAAACCGTACGTTTGTTCTATTTGTAGTAAAGGTTTTGTTCGGGAAGATCTTTTAATTAGACATCAAATTGTGCACAATGCCCGGTTAAATCTAAAACAGGAAGATGATTTAATGGAGACAGACATCAAATTGAATTGTTCGTTCTGCGATAAAGTTTTCCATAAAAAAGAAAGTCTCTCCTCTCATATGCGTACCCACACGAGCATCGTTCGGAAAATTTTAACCTGTGAAGTGTGTCTGAAAAAATTCTCCAAACCTAGCCAGTTGACGCGGCACGTTAAAATCCATGCATCAATTAAACCACACATTTGCCAATTATGTGAGAAAGGCTTTGCACGTGGGGAACAGTTGATAAATCATATGAACGTACATTCTGGCGTCAAACCTCACGTTTGTGAAATTTGCGATAAAGGCTTCAACcaaataagtaatttaaaagatCATATGCGCACCCACaacggtgaaaaaccatttttgtGTTCAACTTGCGGAAAAGGGTTCAATCAATTGGGTAATTTACGTCAACACACAGTTCGACATAGTGGTATCAAAGCTCATTTGTGTAACACATGTGGCAACGCATTTGCCAGCAAAGGAGAACTAGGTGCCCATTTACGTAAACATACCGGCGTTCGACCGTACGTTTGCAACATTTGTAATCACGGTTTCACCACATCCAGCTCGTTGACCAAACACAAACGAATTCATAGTGGGGAGAAACCATATGAATGTGATGTGTGCCATATGAAGTTTTCACGTAGTGGCATATTGGCACGTCACAAACGTACAcataccggtgaaaaaccatacgttTGCACTTTTTGTACCAAAGCATTTTCCCAAAGTAATGATCTTAGTTCCCATTTGCGTATTCATACCGGTGAGAAACCGTACATATGTGATGTTTGTGGTCAAGCATTTCGTCAAAGTTCGGCGCTTAAGacgcataaaaaaatacatatggATAGAAGTGCGTTAGTTGAGAATAGAGCGGCGGTGGCAACGTTAGCACTAGTTCAGTCAGCGTTTCTCAATAGTTTACAGACaattaaatag
Protein Sequence: MEDKPEIALDKICRACMAENVEMRSIFVPDENLDTNIHLSEMIMAYAAVQITLGDGLPEQICLDCASQVSKTYSFKQQCERSDAALREKLGLEKLVLPKEEVVHSLNPTSVFDSEEIVIKPEIKEINGDDDDDDYPEMHAEITAAPIGSEDELLGDEDMQNAMNNIKQEVENEKEALEKFNDISYDIRKIHTCPICKKSFNRNSHLSRHLRVHTAEKPYVCSICSKGFVREDLLIRHQIVHNARLNLKQEDDLMETDIKLNCSFCDKVFHKKESLSSHMRTHTSIVRKILTCEVCLKKFSKPSQLTRHVKIHASIKPHICQLCEKGFARGEQLINHMNVHSGVKPHVCEICDKGFNQISNLKDHMRTHNGEKPFLCSTCGKGFNQLGNLRQHTVRHSGIKAHLCNTCGNAFASKGELGAHLRKHTGVRPYVCNICNHGFTTSSSLTKHKRIHSGEKPYECDVCHMKFSRSGILARHKRTHTGEKPYVCTFCTKAFSQSNDLSSHLRIHTGEKPYICDVCGQAFRQSSALKTHKKIHMDRSALVENRAAVATLALVQSAFLNSLQTIK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01061553;
90% Identity: iTF_00240329;
80% Identity: iTF_00240329;