Basic Information

Insect: Bombus sibiricus
Gene Symbol: Hr39
Assembly: GCA_014737505.1
Location: JACXIM010000107.1:105627-133273[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3 2.3e+04 -5.8 5.7 124 151 42 69 22 100 0.47

2 5 1 7.8e+03 -3.7 7.3 72 163 308 401 280 420 0.48

3 5 3 2.3e+04 -8.0 13.8 69 160 420 526 395 543 0.51

4 5 1.6e-07 0.0013 18.6 0.1 1 19 609 627 609 632 0.95

5 5 2.6e-71 2e-67 228.8 0.2 89 408 668 986 636 986 0.75

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3	2.3e+04	-5.8	5.7	124	151	42	69	22	100	0.47
2	5	1	7.8e+03	-3.7	7.3	72	163	308	401	280	420	0.48
3	5	3	2.3e+04	-8.0	13.8	69	160	420	526	395	543	0.51
4	5	1.6e-07	0.0013	18.6	0.1	1	19	609	627	609	632	0.95
5	5	2.6e-71	2e-67	228.8	0.2	89	408	668	986	636	986	0.75

Sequence Information

Coding Sequence: ATGTCGGAGCAAAACGGGCCCAGCGAGGGCCCTGGACCGGGCCCAGGGCCGGGTCCTGGTTGGTGGCCAACCTCACAGTCCTGGAAGACGAACTCCTGCACCGCTGCCTCCTCGTCTACTTGTTCAACCGTTCCAGACAACTCCGCCTCCGTCTCTGCCTCTTGCACCACCTCCACGTCCTCCCTGGCGACCACCACATCGGCCACTTCATCGACCAGCTGCTGTTCCTCCACCCCTGGCGGTGGACCGTCTTGCACGATCACCGCGGCCCGCTCCTCCGAAACGGGAAAGAACGTCTCCGTCACGACGATCAATGTACCCCCTAATCAGGACATGCACGATGGCAAGGGTATATGCAAGTATCTTGGCGGCCAGAATGGCGTGACGGTATCGGTAGTGTCAAGCTGTGGCTCCATACTGGGATGTGGAAACGCGAATGTTGTGTCTACCACGGGGATAGGCAGTAGCACCGGTACACAGAGTATTGGCATCGGAGTGAACATCCTTGAACAGAGCACGGCGGATGATGACGCGGAGGATAGCGACGTTGAGATAAGCAAAATCGACTTCCGAGGGGTGAATTTGCGTACGAAGAAGAAACGAGACGTGTCTGGTAGTCAGAGTCAAAGCGGGGAGAAAATCGGCGATGGAGAGGTCGAGGATGGGAACGGTTGTTACGATGGAAGCGATGCGTCTCAGCAACAACCGGAGAGGCCCATGTCATGGGAGGGAGAACTATCCGATCAAGAAATGTCTTCCAATACGATTACAAATCAAGATACACACGAGGACACGTCAATGGAGGGTGTTCAAGTATGTGGCGCGAGTCCCGGACCAATGGAACAAAAATTTCCCATAAAACCAGAACCAGATTTTCAGTCCAACCCAGGTTTCACATTTGGCTCTTTTCACGACACCGGATTACCTCTGAATCACGGCCAGCAAATACAACAACAGCAACAACAGCAACAACAGCGCAACATTGAGAATCTCGAACAAACACAACAAAACGATTTGCCTCTTCTCGTAGGAAAATTACTCGGTGGTTACAATAGTTCGACTCCGAATCACAGTCCAGTGTTGAATCCTAGACACCATTTAACAAAGCATAGCCACACGAGATCGCAGGTGCCGTCACCGGACTCGGCCATTCATTCCGCATACAGCGTATTCAGCTCCCCGACGCAAAGTCCTCACGCAACTCGCCACTCCCCCCTGGGCGCGGCAAGTCCAGTTCCATCTTCGTCGCTATCCTTGTCACGACACAGTTTCAACAATTCCACTTCCTCGTTGTCGCTCTCGTTGTCACACTCCCTCTCGAGAAACAATTCGGACGCCTCGAGCAGCTGCTACAGCTACGGCTCTCTCAGCCCACCCACACACTCGCCCGTCCAGCAACCGAGACATCCGCAGCATCACCAGCATCAAGTTGCTCAAGGAAGCCCACTTCATCTGCCAGCAACCGCTTCTCCCGCCATTACTCATCACTACACTTCCTCTGCACCGGGTTCTGAGCTATCTCCAGAAGGACACGTTGCTACAGACGATCAGGAAGACTGTAGAATACCCTCGGCACCGTCTGGTATATCCACAAGGCAGCAACTAATCAATACCCCGTGTCCAATTTGCGGGGATAAGATCAGTGGTTTTCATTATGGAATATTCTCGTGCGAGTCGTGCAAGGGATTTTTCAAACGCACCGTCCAGAATCGAAAGAATTATGTGTGCCTTAGAGGCGCGGGCTGTCCAGTCACCGTTGTTACCAGGAAAAAATGCCCCGCCTGCAGATTCGAAAAGTGCCTCAGTATGGGTATGAAGCTCGAGGCGATTAGGGAGGATCGCACCAGGGGTGGCAGAAGTACCTATCAGTGTACATATACTTTTCCACCAAATTTTGTCGGTAGTCCTGCAAGTAACATGCCCAGCGACAAATTAGCTACCGGAGGAAATTGTAGTCCAGCTCCAGCTGGTAACGAACATCACTATCCGGCAAGGCACCATTCGAATCACTCCCATAAGATGCAAATGGTACCGCAACTTCTACAGGATATCATGGACGTAGAGCACTTGTGGCATTACAATGATAACGATCGTATGACTGGGATTCAAAACGCAGGGACGAATCTTACTAGAAACAACGATTCAATGTTATTGAGTGTTAGAAGTAACGGAGGATCTGGAATAGAGAACGACACAGGTTCAGGTATCGAGTGTCCCTCCAATAGAACTACAGGAAACGGTAATCCTAGTAATAGAAGAGATAACAGATCATGCTCCAATGTTTCTACTGTTGCTAACGAACAACATGCTGCATCCGTTGGTAACAGTTCTCAAATCAACAATACGAATTGTAATCCAACTCAACATCCCGATTTTCTGTCCAACCTCTGCAATATCGCTGATCATCGACTCTACAAAATAGTGAAGTGGTGCAAGAGTTTGCCGTTATTTAAAAACATTTCGATCGATGATCAGATCTGTCTGTTGATTAATTCTTGGTGCGAGCTACTGCTCTTCTCATGCTGCTTTCGCAGTATGAGCACTCCCGGTGAAATTAGAGTGTCTCTCGGTAAGTCGATTACACTGGAACAAGCTAGGCAGCTTGGCTTAGCGACCTGTATCGAGAGGATGCTTGCATTTACTAACAATTTGAGAAGGCTCCGAGTAGATCAGTACGAATACGTGGCGATGAAGGTAATAGTACTGTTGACCTCTGATACAAGTGAACTGAAAGAACCTGAAAAAGTTAGAGCATCTCAGGAAAAGGCTTTACAAGCATTGCAACAATATACTATCGCAAGGTACCCAGAAATGCCTGCTAAATTTGGTGAATTATTATTGAGAATTCCAGATTTACAAAGAACATGCCAAGCAGGAAAGGAATTATTAAGTGCTAAACGTGCTGAAGGAGAAGGTAGCTCGTTTAATCTGTTGATGGAATTGTTGAGAGGAGATCACTGA
Protein Sequence: MSEQNGPSEGPGPGPGPGPGWWPTSQSWKTNSCTAASSSTCSTVPDNSASVSASCTTSTSSLATTTSATSSTSCCSSTPGGGPSCTITAARSSETGKNVSVTTINVPPNQDMHDGKGICKYLGGQNGVTVSVVSSCGSILGCGNANVVSTTGIGSSTGTQSIGIGVNILEQSTADDDAEDSDVEISKIDFRGVNLRTKKKRDVSGSQSQSGEKIGDGEVEDGNGCYDGSDASQQQPERPMSWEGELSDQEMSSNTITNQDTHEDTSMEGVQVCGASPGPMEQKFPIKPEPDFQSNPGFTFGSFHDTGLPLNHGQQIQQQQQQQQQRNIENLEQTQQNDLPLLVGKLLGGYNSSTPNHSPVLNPRHHLTKHSHTRSQVPSPDSAIHSAYSVFSSPTQSPHATRHSPLGAASPVPSSSLSLSRHSFNNSTSSLSLSLSHSLSRNNSDASSSCYSYGSLSPPTHSPVQQPRHPQHHQHQVAQGSPLHLPATASPAITHHYTSSAPGSELSPEGHVATDDQEDCRIPSAPSGISTRQQLINTPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGAGCPVTVVTRKKCPACRFEKCLSMGMKLEAIREDRTRGGRSTYQCTYTFPPNFVGSPASNMPSDKLATGGNCSPAPAGNEHHYPARHHSNHSHKMQMVPQLLQDIMDVEHLWHYNDNDRMTGIQNAGTNLTRNNDSMLLSVRSNGGSGIENDTGSGIECPSNRTTGNGNPSNRRDNRSCSNVSTVANEQHAASVGNSSQINNTNCNPTQHPDFLSNLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSMSTPGEIRVSLGKSITLEQARQLGLATCIERMLAFTNNLRRLRVDQYEYVAMKVIVLLTSDTSELKEPEKVRASQEKALQALQQYTIARYPEMPAKFGELLLRIPDLQRTCQAGKELLSAKRAEGEGSSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00733987;
90% Identity: iTF_00228733;
80% Identity: iTF_00227333;